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ONTOLOGY REPORT - ANNOTATIONS


Term:gamma-delta intraepithelial T cell differentiation
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Accession:GO:0002304 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: gamma-delta intraepithelial T lymphocyte differentiation
 related_synonym: gamma-delta intraepithelial T cell development



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CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR9 C-C motif chemokine receptor 9 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5629467|PMID:25348153) MGI
Ensembl
PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr 3:45,719,655...45,810,964
Ensembl chr 3:46,900,845...46,917,443
JBrowse link
G GPR18 G protein-coupled receptor 18 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5629467|PMID:25348153) MGI
Ensembl
PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr13:80,423,534...80,427,604
Ensembl chr13:99,562,589...99,563,584
JBrowse link
G LOC100990924 NKG2-A/NKG2-B type II integral membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:10,469,351...10,576,060
Ensembl chr12:10,720,723...10,744,046
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15355
    immune system process 2127
      leukocyte activation 928
        lymphocyte activation 751
          T cell activation 524
            T cell differentiation 299
              gamma-delta T cell differentiation 17
                gamma-delta intraepithelial T cell differentiation 3
                  CD4-positive gamma-delta intraepithelial T cell differentiation 0
                  CD8-positive, gamma-delta intraepithelial T cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 15355
    cellular process 14032
      cellular developmental process 4039
        cell differentiation 4015
          cell development 2887
            hemopoiesis 947
              leukocyte differentiation 605
                mononuclear cell differentiation 458
                  lymphocyte differentiation 403
                    T cell differentiation 299
                      gamma-delta T cell differentiation 17
                        gamma-delta intraepithelial T cell differentiation 3
                          CD4-positive gamma-delta intraepithelial T cell differentiation 0
                          CD8-positive, gamma-delta intraepithelial T cell differentiation 3
paths to the root