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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell differentiation involved in immune response
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Accession:GO:0002292 term browser browse the term
Definition:The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:related_synonym: T cell development involved in immune response;   T cell differentiation during immune response;   T-lymphocyte differentiation during immune response



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T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC4D C-type lectin domain family 4 member D acts_upstream_of_or_within ISO (MGI:5525050|PMID:23602766) MGI PMID:23602766 MGI:5525050 NCBI chr12:8,599,654...8,608,494
Ensembl chr12:8,814,680...8,823,484
JBrowse link
G CLEC4E C-type lectin domain family 4 member E acts_upstream_of_or_within ISO (MGI:5525050|PMID:23602766) MGI PMID:23602766 MGI:5525050 NCBI chr12:8,620,618...8,627,610 JBrowse link
G FCER1G Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (MGI:5525050|PMID:23602766) MGI PMID:23602766 MGI:5525050 NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810
JBrowse link
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:131,489,446...131,519,864
Ensembl chr 1:135,321,288...135,350,724
JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:27,601,829...27,608,701
Ensembl chr 3:27,925,086...27,930,274
JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:3829555|PMID:17277142) MGI PMID:17277142 MGI:3829555 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSC1 TSC complex subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5608813|PMID:25271321) MGI
Ensembl
PMID:25271321 GO_REF:0000107 MGI:5608813 NCBI chr 9:104,007,708...104,060,938
Ensembl chr 9:132,638,003...132,675,759
JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGL2 fibrinogen like 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6188369|PMID:29341118) MGI
Ensembl
PMID:29341118 GO_REF:0000107 MGI:6188369 NCBI chr 7:69,114,082...69,120,575
Ensembl chr 7:82,926,266...82,932,550
JBrowse link
G LOC100976419 interferon lambda-1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:36,394,462...36,397,363
Ensembl chr19:44,942,186...44,944,519
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G JAK3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chr19:17,299,129...17,330,700
Ensembl chr19:18,283,560...18,300,964
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G IL2 interleukin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:3817792|PMID:18792410) MGI PMID:18792410 MGI:3817792 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:93,975,164...94,031,516
Ensembl chr 9:122,313,791...122,365,102
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chr18:42,306,324...42,337,214 JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5450776|PMID:23034280) MGI
Ensembl
PMID:23034280 GO_REF:0000107 MGI:5450776 NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOXL3 lysyl oxidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,598,870...74,622,502
Ensembl chr2A:76,105,957...76,128,495
JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chr 1:148,528,535...148,662,839
Ensembl chr 1:152,251,683...152,262,668
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2450484|PMID:12594267) MGI
Ensembl
PMID:12594267 GO_REF:0000107 MGI:2450484 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) UniProt PMID:12242343 MGI:3687909 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041
JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RC3H1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3580753|PMID:15917799) MGI
Ensembl
PMID:15917799 GO_REF:0000107 MGI:3580753 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G LGALS9 galectin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959
JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617
JBrowse link
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) BHF-UCL PMID:18713990 MGI:3806904 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:3576832 NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2176424|PMID:11894097) MGI
Ensembl
PMID:11894097 GO_REF:0000107 MGI:2176424 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) UniProt PMID:12242343 MGI:3687909 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041
JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574
JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr19:32,805,772...32,817,778
Ensembl chr19:41,553,727...41,568,555
JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:98,914,957...98,948,467
Ensembl chr 3:105,616,645...105,628,300
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216
JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617
JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216
JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855
JBrowse link
G RARA retinoic acid receptor alpha involved_in ISO (PMID:18416830) BHF-UCL PMID:18416830 NCBI chr17:16,932,485...16,980,958 JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) BHF-UCL PMID:18354165 MGI:4943387 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYB MYB proto-oncogene, transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:132,952,728...132,990,560
Ensembl chr 6:137,048,812...137,086,194
JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5617929|PMID:24645804) MGI
Ensembl
PMID:24645804 GO_REF:0000107 MGI:5617929 NCBI chr 9:37,768,566...37,921,897 JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3051162|PMID:15240675) MGI
Ensembl
PMID:15240675 GO_REF:0000107 MGI:3051162 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27 interleukin 27 involved_in ISO (PMID:12734330) UniProt PMID:12734330
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr2B:115,052,768...115,056,479
Ensembl chr2B:233,862,505...233,866,225
JBrowse link
G CCR6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr 6:165,094,563...165,109,774
Ensembl chr 6:170,069,689...170,084,779
JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3817343|PMID:18776904) MGI PMID:18776904 MGI:3817343 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729
JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 involved_in ISO (MGI:5607369|PMID:24859450) UniProt PMID:24859450 MGI:5607369 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G GPR183 G protein-coupled receptor 183 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:80,461,908...80,475,046
Ensembl chr13:99,601,220...99,602,305
JBrowse link
G IL21 interleukin 21 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5486592|PMID:23583643) MGI
Ensembl
PMID:23583643 GO_REF:0000107 MGI:5486592 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5486592|PMID:23583643) MGI
Ensembl
PMID:23583643 GO_REF:0000107 MGI:5486592 NCBI chr 9:93,975,164...94,031,516
Ensembl chr 9:122,313,791...122,365,102
JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRACR2A calcium release activated channel regulator 2A involved_in ISO (PMID:29987160)
(MGI:6195365|PMID:29987160)
UniProt PMID:29987160 MGI:6195365 NCBI chr12:3,729,241...3,875,715
Ensembl chr12:3,655,031...3,737,592
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G HMGB1 high mobility group box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G IL18R1 interleukin 18 receptor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2136797|PMID:10227969) MGI
Ensembl
PMID:10227969 GO_REF:0000107 MGI:2136797 NCBI chr2A:99,419,686...99,462,650 JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3621346|PMID:16081776) MGI
Ensembl
PMID:16081776 GO_REF:0000107 MGI:3621346 NCBI chr19:41,948,559...41,987,121
Ensembl chr19:50,554,864...50,590,223
JBrowse link
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:131,489,446...131,519,864
Ensembl chr 1:135,321,288...135,350,724
JBrowse link
G TMEM98 transmembrane protein 98 involved_in ISO (MGI:6294180|PMID:25946230) UniProt PMID:25946230 MGI:6294180 NCBI chr17:23,844,747...23,858,390
Ensembl chr17:24,133,357...24,146,912
JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:4838368|PMID:20706986) MGI PMID:20706986 MGI:4838368 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G SPN sialophorin involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,035,243...30,036,445 JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,075,768...56,100,749
Ensembl chr14:74,919,115...74,943,652
JBrowse link
G ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,276,454...96,323,287
Ensembl chr10:99,768,566...99,813,568
JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,461,553...40,200,118
Ensembl chr15:57,771,735...57,980,460
JBrowse link
G RORC RAR related orphan receptor C acts_upstream_of_or_within
involved_in
ISO (MGI:3817792|PMID:18792410)
(MGI:3692468|PMID:16990136), (MGI:3772713|PMID:18164222)
MGI
GO_Central
PMID:16990136 PMID:18164222 PMID:18792410 MGI:3692468 MGI:3772713 MGI:3817792 NCBI chr 1:127,164,725...127,190,479
Ensembl chr 1:130,808,705...130,834,490
JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,075,768...56,100,749
Ensembl chr14:74,919,115...74,943,652
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:3692468|PMID:16990136)
(MGI:6142555|PMID:27893700)
UniProt PMID:16990136 PMID:27893700 MGI:3692468 MGI:6142555 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089
JBrowse link
G IRF4 interferon regulatory factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:206,282...226,487
Ensembl chr 6:342,718...356,654
JBrowse link
G LY9 lymphocyte antigen 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:136,151,608...136,185,365
Ensembl chr 1:140,075,646...140,107,784
JBrowse link
G OTUD5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO (MGI:5621075|PMID:25470037) MGI PMID:25470037 MGI:5621075 NCBI chr  X:41,219,536...41,256,219 JBrowse link
G SLAMF6 SLAM family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:135,838,862...135,878,207
Ensembl chr 1:139,761,121...139,799,348
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,075,768...56,100,749
Ensembl chr14:74,919,115...74,943,652
JBrowse link
G BCL3 BCL3 transcription coactivator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3621346|PMID:16081776) MGI
Ensembl
PMID:16081776 GO_REF:0000107 MGI:3621346 NCBI chr19:41,696,162...41,708,485
Ensembl chr19:50,304,171...50,313,005
JBrowse link
G BCL6 BCL6 transcription repressor acts_upstream_of
involved_in
ISO
IEA
(MGI:2450484|PMID:12594267) MGI
Ensembl
PMID:12594267 GO_REF:0000107 MGI:2450484 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:4838368|PMID:20706986) MGI PMID:20706986 MGI:4838368 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:4838368|PMID:20706986) MGI PMID:20706986 MGI:4838368 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL6 interleukin 6 acts_upstream_of ISO (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chr 7:23,415,922...23,420,767 JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (MGI:61362|PMID:8434133) MGI PMID:8434133 MGI:61362 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756
JBrowse link
G IL12B interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:154,706,467...154,722,231
Ensembl chr 5:161,325,303...161,335,381
JBrowse link
G PTGER4 prostaglandin E receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148
JBrowse link
G RORC RAR related orphan receptor C involved_in ISO (MGI:2686818|PMID:14691482) UniProt PMID:14691482 MGI:2686818 NCBI chr 1:127,164,725...127,190,479
Ensembl chr 1:130,808,705...130,834,490
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15327
    immune system process 2279
      leukocyte activation 911
        lymphocyte activation 739
          lymphocyte differentiation 392
            T cell differentiation 290
              T cell differentiation involved in immune response 73
                alpha-beta T cell differentiation involved in immune response + 65
                gamma-delta T cell differentiation involved in immune response 0
                memory T cell differentiation + 9
Path 2
Term Annotations click to browse term
  biological_process 15327
    developmental process 6162
      anatomical structure development 5753
        multicellular organism development 4942
          system development 4511
            immune system development 1036
              hematopoietic or lymphoid organ development 972
                hemopoiesis 924
                  leukocyte differentiation 583
                    mononuclear cell differentiation 447
                      lymphocyte differentiation 392
                        T cell differentiation 290
                          T cell differentiation involved in immune response 73
                            alpha-beta T cell differentiation involved in immune response + 65
                            gamma-delta T cell differentiation involved in immune response 0
                            memory T cell differentiation + 9
paths to the root