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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell activation involved in immune response
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Accession:GO:0002286 term browser browse the term
Definition:The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: T cell activation during immune response;   T lymphocyte activation during immune response


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T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1C CD1c molecule ISO (PMID:21167756) UniProtKB PMID:21167756 NCBI chr38:23,328,183...23,331,270 JBrowse link
G CD74 CD74 molecule IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151
JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 ISO (MGI:MGI:5544501|PMID:24310610) UniProtKB PMID:24310610 MGI:MGI:5544501 NCBI chr30:7,144,727...7,248,014
Ensembl chr30:7,144,570...7,248,000
JBrowse link
G F2RL1 F2R like trypsin receptor 1 ISS UniProtKB GO_REF:0000024 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180
JBrowse link
G IFNA5 interferon, alpha 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,726,568...40,727,131
Ensembl chr11:40,726,568...40,727,131
JBrowse link
G IFNA7 interferon, alpha 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,862,587...40,863,150
Ensembl chr11:40,862,587...40,863,150
JBrowse link
G IFNK interferon kappa IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:45,641,627...45,642,256
Ensembl chr11:45,641,627...45,642,256
JBrowse link
G LCP1 lymphocyte cytosolic protein 1 IEA Ensembl GO_REF:0000107 NCBI chr22:4,955,453...5,059,654
Ensembl chr22:4,992,347...5,059,636
JBrowse link
G LOC100685213 interferon alpha-1/2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,816,731...40,817,513 JBrowse link
G LOC100687928 interferon alpha-1/2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,749,643...40,750,398 JBrowse link
G LOC100688084 interferon alpha-1/2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,765,515...40,766,521 JBrowse link
G MDK midkine ISO (MGI:MGI:5897914|PMID:28183532) UniProt PMID:28183532 MGI:MGI:5897914 NCBI chr 9:55,100,491...55,101,081 JBrowse link
G PSEN1 presenilin 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532
JBrowse link
G PSEN2 presenilin 2 ISO (MGI:MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:MGI:3760494 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722
JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr23:16,476,498...16,512,406
Ensembl chr23:16,506,032...16,511,527
JBrowse link
G IFNG interferon gamma ISO (MGI:MGI:3829555|PMID:17277142) MGI PMID:17277142 MGI:MGI:3829555 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB27A RAB27A, member RAS oncogene family IEA Ensembl GO_REF:0000107 NCBI chr30:20,633,576...20,706,240
Ensembl chr30:20,635,400...20,690,521
JBrowse link
G STX11 syntaxin 11 ISO (MGI:MGI:5460953|PMID:23042080), (MGI:MGI:5471188|PMID:23190531) MGI PMID:23042080, PMID:23190531 MGI:MGI:5460953, MGI:MGI:5471188 NCBI chr 1:35,600,440...35,645,421
Ensembl chr 1:35,601,133...35,644,819
JBrowse link
memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSC1 TSC complex subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:51,409,307...51,459,546
Ensembl chr 9:51,425,937...51,454,677
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEACAM1 CEA cell adhesion molecule 1 ISO (PMID:18424730) UniProtKB PMID:18424730 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830
JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGL2 fibrinogen like 2 IEA Ensembl GO_REF:0000107 NCBI chr18:17,328,794...17,335,429
Ensembl chr18:17,331,780...17,335,401
JBrowse link
G IL29L interleukin 29-like ISO (PMID:19346497) UniProtKB PMID:19346497 NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017
JBrowse link
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393
JBrowse link
G LGALS3 galectin 3 ISO (MGI:MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:MGI:4355752 NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4R interleukin 4 receptor ISO (MGI:MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:MGI:3761239 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G JAK3 Janus kinase 3 ISO (MGI:MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:MGI:3719947 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805
JBrowse link
G TNFSF4 TNF superfamily member 4 ISO (MGI:MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:MGI:4942267 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 IEA Ensembl GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G IL2 interleukin 2 IEA Ensembl GO_REF:0000107 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G IL4 interleukin 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341
JBrowse link
G SMAD7 SMAD family member 7 IEA Ensembl GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749
JBrowse link
G TBX21 T-box transcription factor 21 ISO (MGI:MGI:4868293|PMID:21151104) UniProtKB PMID:21151104 MGI:MGI:4868293 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B IEA Ensembl GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A IEA Ensembl GO_REF:0000107 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOXL3 lysyl oxidase like 3 ISO (MGI:MGI:5825383|PMID:28065600) UniProtKB PMID:28065600 MGI:MGI:5825383 NCBI chr17:48,590,996...48,610,264
Ensembl chr17:48,591,768...48,610,392
JBrowse link
G TBX21 T-box transcription factor 21 IEA Ensembl GO_REF:0000107 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261
JBrowse link
G TNFSF18 TNF superfamily member 18 ISO (MGI:MGI:5551556|PMID:24107315) UniProtKB PMID:24107315 MGI:MGI:5551556 NCBI chr 7:25,983,064...25,994,605
Ensembl chr 7:25,963,719...25,992,801
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011
JBrowse link
G BCL6 BCL6 transcription repressor IEA Ensembl GO_REF:0000107 NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704
JBrowse link
G HLX H2.0 like homeobox IEA Ensembl GO_REF:0000107 NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152
JBrowse link
G LOC111089966 zinc finger protein 271 IEA Ensembl GO_REF:0000107 NCBI chr 7:54,714,912...54,727,638 JBrowse link
G SOCS5 suppressor of cytokine signaling 5 IEA Ensembl GO_REF:0000107 NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452
JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RC3H1 ring finger and CCCH-type domains 1 ISO (MGI:MGI:3580753|PMID:15917799) MGI PMID:15917799 MGI:MGI:3580753 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174
JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma IEA Ensembl GO_REF:0000107 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G LGALS9 galectin 9 ISO (PMID:20209097) UniProtKB PMID:20209097 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391
JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL23A interleukin 23 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359
JBrowse link
G LOC609365 CD46 molecule, complement regulatory protein-like ISO (PMID:12540904) UniProtKB PMID:12540904 NCBI chr 7:6,602,762...6,646,561 JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 ISO (MGI:MGI:6119963|PMID:29230018) UniProt PMID:29230018 MGI:MGI:6119963 NCBI chr24:42,538,858...42,544,200
Ensembl chr24:42,538,882...42,544,198
JBrowse link
G TNFSF4 TNF superfamily member 4 ISO (MGI:MGI:3806904|PMID:18713990) BHF-UCL PMID:18713990 MGI:MGI:3806904 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892
JBrowse link
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule IEA Ensembl GO_REF:0000107 NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868
JBrowse link
G DLA-DMB major histocompatibility complex, class II, DM beta ISO (PMID:8139689) UniProtKB PMID:8139689 NCBI chr12:2,503,325...2,508,380
Ensembl chr12:2,503,325...2,533,990
JBrowse link
G LGALS9 galectin 9 ISO (PMID:16116184) UniProtKB PMID:16116184 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391
JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011
JBrowse link
G CCL19 C-C motif chemokine ligand 19 ISO (MGI:MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:MGI:3576832 NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365
JBrowse link
G HLX H2.0 like homeobox IEA Ensembl GO_REF:0000107 NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 IEA Ensembl GO_REF:0000107 NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452
JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase IEA Ensembl GO_REF:0000107 NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927
JBrowse link
G MIR326 microRNA mir-326 ISO (MGI:MGI:4436838|PMID:19838199) MGI PMID:19838199 MGI:MGI:4436838 NCBI chr21:23,240,463...23,240,553
Ensembl chr21:23,240,463...23,240,553
JBrowse link
G NFKBID NFKB inhibitor delta IEA Ensembl GO_REF:0000107 NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
G NFKBIZ NFKB inhibitor zeta IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 IEA Ensembl GO_REF:0000107 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059
JBrowse link
G NXPE3 neurexophilin and PC-esterase domain family member 3 IEA Ensembl GO_REF:0000107 NCBI chr33:8,073,254...8,120,253
Ensembl chr33:8,073,840...8,154,561
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP IEA Ensembl GO_REF:0000107 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL23A interleukin 23 subunit alpha IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359
JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 IEA Ensembl GO_REF:0000107 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL4R interleukin 4 receptor ISO (MGI:MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:MGI:3761239 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G IL6 interleukin 6 ISO (MGI:MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:MGI:2450484 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 IEA Ensembl GO_REF:0000107 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059
JBrowse link
G PRKCZ protein kinase C zeta IEA Ensembl GO_REF:0000107 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664
JBrowse link
G RARA retinoic acid receptor alpha IEA Ensembl GO_REF:0000107 NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459
JBrowse link
G TNFSF4 TNF superfamily member 4 ISO (MGI:MGI:4943387|PMID:18354165) BHF-UCL PMID:18354165 MGI:MGI:4943387 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892
JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYB MYB proto-oncogene, transcription factor IEA Ensembl GO_REF:0000107 NCBI chr 1:27,908,309...27,991,984
Ensembl chr 1:27,908,364...27,991,969
JBrowse link
G SHB SH2 domain containing adaptor protein B IEA Ensembl GO_REF:0000107 NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325
JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor IEA Ensembl GO_REF:0000107 NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704
JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27 interleukin 27 IEA Ensembl GO_REF:0000107 NCBI chr 6:18,243,988...18,248,369
Ensembl chr 6:18,244,040...18,247,635
JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 NOT ISO (MGI:MGI:3820359|PMID:19050256) UniProtKB PMID:19050256 MGI:MGI:3820359 NCBI chr25:40,506,385...40,509,903
Ensembl chr25:40,506,753...40,509,709
JBrowse link
G CCR6 C-C motif chemokine receptor 6 NOT ISO (MGI:MGI:3820359|PMID:19050256) UniProtKB PMID:19050256 MGI:MGI:3820359 NCBI chr 1:54,932,798...54,960,646
Ensembl chr 1:54,932,690...54,959,740
JBrowse link
G MIR301A microRNA mir-301a ISO (MGI:MGI:5426073|PMID:22517757) MGI PMID:22517757 MGI:MGI:5426073 NCBI chr 9:33,724,572...33,724,655
Ensembl chr 9:33,724,571...33,724,655
JBrowse link
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein IEA Ensembl GO_REF:0000107 NCBI chr 2:7,151,443...7,250,412
Ensembl chr 2:7,151,443...7,212,200
JBrowse link
G FGL2 fibrinogen like 2 IEA Ensembl GO_REF:0000107 NCBI chr18:17,328,794...17,335,429
Ensembl chr18:17,331,780...17,335,401
JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEA Ensembl GO_REF:0000107 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914
JBrowse link
G ITGAL integrin subunit alpha L IEA Ensembl GO_REF:0000107 NCBI chr 6:17,605,611...17,645,134
Ensembl chr 6:17,605,760...17,644,986
JBrowse link
T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc fragment of IgE receptor Ig IEA Ensembl GO_REF:0000107 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940
JBrowse link
G LOC611536 C-type lectin domain family 4 member D ISO (MGI:MGI:5525050|PMID:23602766) MGI PMID:23602766 MGI:MGI:5525050 NCBI chr27:37,520,289...37,559,920
Ensembl chr27:37,551,064...37,558,847
JBrowse link
G LOC611538 C-type lectin domain family 4 member E IEA Ensembl GO_REF:0000107 NCBI chr27:37,561,445...37,568,652
Ensembl chr27:37,563,038...37,568,463
JBrowse link
G SEMA4A semaphorin 4A ISO (MGI:MGI:3574161|PMID:15780988) UniProtKB PMID:15780988 MGI:MGI:3574161 NCBI chr 7:41,670,814...41,695,349
Ensembl chr 7:41,672,120...41,692,460
JBrowse link
T cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule ISO RGD PMID:20500684 RGD:4892204 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G RPS6 ribosomal protein S6 IEA Ensembl GO_REF:0000107 NCBI chr11:39,161,422...39,165,148
Ensembl chr11:39,161,422...39,165,148
JBrowse link
G SLC11A1 solute carrier family 11 member 1 IEA Ensembl GO_REF:0000107 NCBI chr37:25,039,203...25,047,461
Ensembl chr37:25,038,360...25,047,282
JBrowse link
G TNFSF18 TNF superfamily member 18 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:25,983,064...25,994,605
Ensembl chr 7:25,963,719...25,992,801
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 IEA Ensembl GO_REF:0000107 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397
JBrowse link
G GPR183 G protein-coupled receptor 183 IEA Ensembl GO_REF:0000107 NCBI chr22:49,332,665...49,347,721
Ensembl chr22:49,333,188...49,347,593
JBrowse link
G IL21 interleukin 21 ISS UniProt GO_REF:0000024 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266
JBrowse link
G IL6 interleukin 6 ISO (MGI:MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:MGI:5450752 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341
JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 IEA Ensembl GO_REF:0000107 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165
JBrowse link
G IL18R1 interleukin 18 receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 IEA Ensembl GO_REF:0000107 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit IEA Ensembl GO_REF:0000107 NCBI chr 1:110,436,677...110,466,709
Ensembl chr 1:110,436,662...110,466,809
JBrowse link
G SEMA4A semaphorin 4A IEA Ensembl GO_REF:0000107 NCBI chr 7:41,670,814...41,695,349
Ensembl chr 7:41,672,120...41,692,460
JBrowse link
G TMEM98 transmembrane protein 98 IEA Ensembl GO_REF:0000107 NCBI chr 9:40,130,421...40,144,120
Ensembl chr 9:40,128,885...40,144,181
JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4 interleukin 4 ISO (MGI:MGI:4838368|PMID:20706986) MGI PMID:20706986 MGI:MGI:4838368 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO (MGI:MGI:5788050|PMID:26410627) MGI PMID:26410627 MGI:MGI:5788050 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114
JBrowse link
G SPN sialophorin ISO (PMID:18036228) UniProtKB PMID:18036228 NCBI chr 6:17,770,303...17,774,946 JBrowse link
G STAT6 signal transducer and activator of transcription 6 IEA Ensembl GO_REF:0000107 NCBI chr10:1,232,515...1,247,011
Ensembl chr10:1,233,691...1,247,075
JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor ISO (MGI:MGI:4456325|PMID:20421391), (MGI:MGI:5004732|PMID:21572431) UniProtKB PMID:20421391, PMID:21572431 MGI:MGI:4456325, MGI:MGI:5004732 NCBI chr 8:48,537,036...48,561,154 JBrowse link
G RORA RAR related orphan receptor A IEA Ensembl GO_REF:0000107 NCBI chr30:25,315,974...26,026,708
Ensembl chr30:25,325,275...26,026,623
JBrowse link
G RORC RAR related orphan receptor C ISO (MGI:MGI:3692468|PMID:16990136), (MGI:MGI:3772713|PMID:18164222)
(MGI:MGI:3817792|PMID:18792410)
UniProtKB
MGI
PMID:16990136, PMID:18164222, PMID:18792410 MGI:MGI:3692468, MGI:MGI:3772713, MGI:MGI:3817792 NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453
JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor IEA Ensembl GO_REF:0000107 NCBI chr 8:48,537,036...48,561,154 JBrowse link
G IL6 interleukin 6 ISS
IEA
UniProtKB
InterPro
GO_REF:0000002, GO_REF:0000024 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G IL6R interleukin 6 receptor ISO (MGI:MGI:6142555|PMID:27893700) UniProt PMID:27893700 MGI:MGI:6142555 NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090
JBrowse link
G IRF4 interferon regulatory factor 4 IEA Ensembl GO_REF:0000107 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339
JBrowse link
G LY9 lymphocyte antigen 9 IEA Ensembl GO_REF:0000107 NCBI chr38:21,522,898...21,554,652
Ensembl chr38:21,523,637...21,554,579
JBrowse link
G OTUD5 OTU deubiquitinase 5 ISO (MGI:MGI:5621075|PMID:25470037) MGI PMID:25470037 MGI:MGI:5621075 NCBI chr  X:42,079,396...42,109,129
Ensembl chr  X:42,081,561...42,108,612
JBrowse link
G SLAMF6 SLAM family member 6 ISO (PMID:22184727) UniProtKB PMID:22184727 NCBI chr38:21,742,228...21,769,521
Ensembl chr38:21,742,301...21,764,494
JBrowse link
G STAT3 signal transducer and activator of transcription 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor IEA Ensembl GO_REF:0000107 NCBI chr 8:48,537,036...48,561,154 JBrowse link
G BCL3 BCL3 transcription coactivator ISO (MGI:MGI:3621346|PMID:16081776) MGI PMID:16081776 MGI:MGI:3621346 NCBI chr 1:110,620,850...110,628,830
Ensembl chr 1:110,620,827...110,654,771
JBrowse link
G GATA3 GATA binding protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760
JBrowse link
G IL4 interleukin 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO (MGI:MGI:61362|PMID:8434133) MGI PMID:8434133 MGI:MGI:61362 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G IL12B interleukin 12B ISS
IEA
UniProtKB
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228
JBrowse link
G PTGER4 prostaglandin E receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358
JBrowse link
G RORC RAR related orphan receptor C ISO (MGI:MGI:2686818|PMID:14691482) UniProtKB PMID:14691482 MGI:MGI:2686818 NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    immune system process 2294
      leukocyte activation 885
        leukocyte activation involved in immune response 272
          lymphocyte activation involved in immune response 190
            T cell activation involved in immune response 104
              T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell + 9
              T cell differentiation involved in immune response + 76
              T cell proliferation involved in immune response + 5
              alpha-beta T cell activation involved in immune response + 68
              cytotoxic T cell degranulation + 3
              gamma-delta T cell activation involved in immune response + 0
Path 2
Term Annotations click to browse term
  biological_process 16187
    cellular process 15463
      cell activation 1013
        cell activation involved in immune response 276
          leukocyte activation involved in immune response 272
            lymphocyte activation involved in immune response 190
              T cell activation involved in immune response 104
                T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell + 9
                T cell differentiation involved in immune response + 76
                T cell proliferation involved in immune response + 5
                alpha-beta T cell activation involved in immune response + 68
                cytotoxic T cell degranulation + 3
                gamma-delta T cell activation involved in immune response + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.