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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell activation involved in immune response
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Accession:GO:0002286 term browser browse the term
Definition:The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: T cell activation during immune response;   T lymphocyte activation during immune response



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T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07049134.3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Cd74 CD74 molecule involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (MGI:5544501|PMID:24310610) RGD PMID:24310610 MGI:5544501 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4839888|PMID:19845798)
UniProt
RGD
PMID:19845798 GO_REF:0000024 MGI:4839888 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Ifna1 interferon, alpha 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,095,767...103,098,260 JBrowse link
G Ifna16l1 interferon, alpha 16-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,216,368...103,216,984 JBrowse link
G Ifna2 interferon alpha 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,258,617...103,259,195 JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,069,483...103,070,052
Ensembl chr 5:103,069,483...103,070,052
JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,187,852...103,188,430 JBrowse link
G Ifnb1 interferon beta 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifne interferon, epsilon involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,538,001...103,627,561
Ensembl chr 5:103,569,675...103,572,256
JBrowse link
G Ifnk interferon kappa involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 involved_in ISO (PMID:17294403) RGD PMID:17294403 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
JBrowse link
G LOC100911527 interferon alpha-12-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302
JBrowse link
G LOC100912314 interferon alpha-1-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,285,510...103,288,640 JBrowse link
G LOC100912356 interferon alpha-1-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,227,820...103,230,500 JBrowse link
G Mdk midkine involved_in ISS
ISO
GO_REF:0000024
(MGI:5897914|PMID:28183532)
UniProt
RGD
PMID:28183532 GO_REF:0000024 MGI:5897914 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (MGI:3760494|PMID:17698590) RGD PMID:17698590 MGI:3760494 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (MGI:3760494|PMID:17698590) RGD PMID:17698590 MGI:3760494 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G RGD1560539 similar to interferon alpha 8/6 precursor; IFNa8/6 (B6) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,476,362...103,477,211 JBrowse link
alpha-beta T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like acts_upstream_of_or_within ISO MGI:3701255 (MGI:3700871|PMID:16476767) RGD PMID:16476767 MGI:3700871
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in IBA
ISO
PMID:21873635
(MGI:4399030|PMID:14605368)
(PMID:17566017)
RGD PMID:14605368 PMID:17566017 PMID:21873635 MGI:4399030, RGD:13792537 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3829555|PMID:17277142) RGD PMID:17277142 MGI:3829555 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsc1 TSC complex subunit 1 acts_upstream_of_or_within ISO MGI:2656240 (MGI:5608813|PMID:25271321) RGD PMID:25271321 MGI:5608813 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO MGI:3582343 (MGI:6188369|PMID:29341118) RGD PMID:29341118 MGI:6188369 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:83,798,651...83,800,297 JBrowse link
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:26492563) RGD PMID:26492563 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Lgals3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) RGD PMID:19706535 MGI:4355752 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:96109 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3719947|PMID:16020505)
BHF-UCL
RGD
PMID:16020505 GO_REF:0000024 MGI:3719947 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) RGD PMID:9670042 MGI:4942267 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:23169781) RGD PMID:23169781 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Il2 interleukin 2 involved_in ISO RNAcentral:URS000039ED8D_10090 (MGI:5634593|PMID:25642768) RGD PMID:25642768 MGI:5634593 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3817792|PMID:18792410)
RGD PMID:18792410 PMID:21873635 MGI:3817792, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933
JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(MGI:5634593|PMID:25642768)
Ensembl
RGD
PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within ISO MGI:3530739 (MGI:5450776|PMID:23034280) RGD PMID:23034280 MGI:5450776 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(MGI:6142401|PMID:25282160)
UniProt
RGD
PMID:25282160 GO_REF:0000024 MGI:6142401 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase-like 3 involved_in ISO (MGI:5825383|PMID:28065600) RGD PMID:28065600 MGI:5825383 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) RGD PMID:24107315 MGI:5551556 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17008549)
UniProt
RGD
PMID:17008549 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:96559 (MGI:2450484|PMID:12594267) RGD PMID:12594267 MGI:2450484 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO MGI:105367|MGI:2182089 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) RGD PMID:12242343 MGI:3687909 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
JBrowse link
G Zfp35 zinc finger protein 35 acts_upstream_of_or_within ISO MGI:4398896 (MGI:4366385|PMID:19783676) RGD PMID:19783676 MGI:4366385 NCBI chr18:15,268,852...15,284,334
Ensembl chr18:15,268,814...15,285,088
JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within ISO MGI:3581675 (MGI:3580753|PMID:15917799) RGD PMID:15917799 MGI:3580753 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) RGD PMID:12540904 NCBI chr13:106,575,586...106,606,325 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6119963|PMID:29230018)
UniProt
RGD
PMID:29230018 GO_REF:0000024 MGI:6119963 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:27591323) RGD PMID:27591323 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:27591323) RGD PMID:27591323 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) RGD PMID:18713990 MGI:3806904 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:1926561|PMID:11046035)
(PMID:8766544)
UniProt
Ensembl
RGD
PMID:8766544 PMID:11046035 GO_REF:0000024 GO_REF:0000107 MGI:1926561 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G RT1-DMb RT1 class II, locus DMb involved_in ISO (PMID:8139689) RGD PMID:8139689 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17008549)
UniProt
RGD
PMID:17008549 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) RGD PMID:15845453 MGI:3576832 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO MGI:105367|MGI:2182089 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070 (MGI:2176424|PMID:11894097) RGD PMID:11894097 MGI:2176424 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) RGD PMID:12242343 MGI:3687909 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260
JBrowse link
G Mir326 microRNA 326 acts_upstream_of_or_within ISO (MGI:4436838|PMID:19838199) RGD PMID:19838199 MGI:4436838 NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:5689221 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23 subunit alpha involved_in IBA
ISO
PMID:21873635
(MGI:3851279|PMID:19501566)
RGD PMID:19501566 PMID:21873635 MGI:3851279, RGD:13792537 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IEA
ISO
GO_REF:0000107
(MGI:3608083|PMID:12829194)
Ensembl
RGD
PMID:12829194 GO_REF:0000107 MGI:3608083 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:96109 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (MGI:2450484|PMID:12594267) RGD PMID:12594267 MGI:2450484 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:5689221 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO
GO_REF:0000024
(MGI:3584076|PMID:15987782)
UniProt
RGD
PMID:15987782 GO_REF:0000024 MGI:3584076 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Rara retinoic acid receptor, alpha involved_in ISO (PMID:18416830) RGD PMID:18416830 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) RGD PMID:18354165 MGI:4943387 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myb MYB proto-oncogene, transcription factor involved_in ISO (PMID:20484083) RGD PMID:20484083 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO MGI:3721903 (MGI:5617929|PMID:24645804) RGD PMID:24645804 MGI:5617929 NCBI chr 5:59,678,066...59,785,443
Ensembl chr 5:59,678,216...59,785,538
JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (MGI:3051162|PMID:15240675) RGD PMID:15240675 MGI:3051162 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il27 interleukin 27 involved_in IBA
ISO
PMID:21873635
(PMID:12734330)
RGD PMID:12734330 PMID:21873635 RGD:13792537 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) RGD PMID:19050256 MGI:3820359 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) RGD PMID:19050256 MGI:3820359 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
JBrowse link
G Mir301a microRNA 301a acts_upstream_of_or_within ISO (MGI:5426073|PMID:22517757) RGD PMID:22517757 MGI:5426073 NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435
JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12rb2 interleukin 12 receptor subunit beta 2 NAS RGD PMID:10651948 RGD:1331512 NCBI chr 4:96,424,615...96,515,327
Ensembl chr 4:96,426,842...96,515,289
JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:15322540) RGD PMID:15322540 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:15322540) RGD PMID:15322540 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein acts_upstream_of_or_within ISO (MGI:3714085|PMID:17403904) RGD PMID:17403904 MGI:3714085 NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010
JBrowse link
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO MGI:3582343 (MGI:6188369|PMID:29341118) RGD PMID:29341118 MGI:6188369 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:2477710) RGD PMID:2477710 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Itgal integrin subunit alpha L involved_in ISO (PMID:2477710) RGD PMID:2477710 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec4d C-type lectin domain family 4, member D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5525050|PMID:23602766)
Ensembl
RGD
PMID:23602766 GO_REF:0000107 MGI:5525050 NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848
JBrowse link
G Clec4e C-type lectin domain family 4, member E involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5013826 (MGI:5525050|PMID:23602766)
Ensembl
RGD
PMID:23602766 GO_REF:0000107 MGI:5525050 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
JBrowse link
G Fcer1g Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2384004 (MGI:5525050|PMID:23602766)
RGD PMID:23602766 PMID:21873635 MGI:5525050, RGD:13792537 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Sema4a semaphorin 4A involved_in ISO (MGI:3574161|PMID:15780988) RGD PMID:15780988 MGI:3574161 NCBI chr 2:173,896,432...173,917,903
Ensembl chr 2:173,896,439...173,914,442
JBrowse link
T cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule IEP RGD PMID:20500684 RGD:4892204 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Rps6 ribosomal protein S6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2387471|MGI:98834 (MGI:3610868|PMID:16357222)
Ensembl
RGD
PMID:16357222 GO_REF:0000107 MGI:3610868 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857755 (MGI:86848|PMID:9176118)
Ensembl
RGD
PMID:9176118 GO_REF:0000107 MGI:86848 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in IBA
ISO
PMID:21873635
(MGI:2682525|PMID:14608036)
RGD PMID:14608036 PMID:21873635 MGI:2682525, RGD:13792537 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:98159 (MGI:3610868|PMID:16357222) RGD PMID:16357222 MGI:3610868 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 involved_in ISO (MGI:5607369|PMID:24859450) RGD PMID:24859450 MGI:5607369 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISS
ISO
GO_REF:0000024
(MGI:5787848|PMID:27147029)
UniProt
RGD
PMID:27147029 GO_REF:0000024 MGI:5787848 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G Il21 interleukin 21 involved_in ISS
ISO
GO_REF:0000024
(MGI:5450752|PMID:23045607)
UniProt
RGD
PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO
GO_REF:0000024
(MGI:5450752|PMID:23045607)
UniProt
RGD
PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within ISO MGI:2442789 (MGI:5486592|PMID:23583643) RGD PMID:23583643 MGI:5486592 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 acts_upstream_of_or_within ISO MGI:2685397 (MGI:5486592|PMID:23583643) RGD PMID:23583643 MGI:5486592 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933
JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cracr2a calcium release activated channel regulator 2A involved_in ISO
IBA
(PMID:29987160)
PMID:21873635
(MGI:6195365|PMID:29987160)
RGD PMID:29987160 PMID:21873635 MGI:6195365, RGD:13792537 NCBI chr 4:160,428,987...160,517,427
Ensembl chr 4:160,408,077...160,518,107
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:15944249) RGD PMID:15944249 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Il18r1 interleukin 18 receptor 1 acts_upstream_of_or_within ISO MGI:2136765 (MGI:2136797|PMID:10227969) RGD PMID:10227969 MGI:2136797 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:4834989|PMID:18579517)
Ensembl
RGD
PMID:18579517 GO_REF:0000107 MGI:4834989 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit acts_upstream_of_or_within ISO MGI:2179545 (MGI:3621346|PMID:16081776) RGD PMID:16081776 MGI:3621346 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Sema4a semaphorin 4A involved_in ISO (MGI:3574161|PMID:15780988) RGD PMID:15780988 MGI:3574161 NCBI chr 2:173,896,432...173,917,903
Ensembl chr 2:173,896,439...173,914,442
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
GO_REF:0000024
(MGI:6294180|PMID:25946230)
UniProt
RGD
PMID:25946230 GO_REF:0000024 MGI:6294180 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4 interleukin 4 acts_upstream_of_or_within ISO MGI:103034 (MGI:4838368|PMID:20706986) RGD PMID:20706986 MGI:4838368 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (MGI:5788050|PMID:26410627) RGD PMID:26410627 MGI:5788050 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Spn sialophorin involved_in ISO
ISS
(PMID:18036228)
GO_REF:0000024
RGD
UniProt
PMID:18036228 GO_REF:0000024 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:96556 (MGI:4838368|PMID:20706986) RGD PMID:20706986 MGI:4838368 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO
IEA
(MGI:1354779|PMID:10761931)
GO_REF:0000107
RGD
Ensembl
PMID:10761931 GO_REF:0000107 MGI:1354779 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:4456325|PMID:20421391), (MGI:5004732|PMID:21572431)
UniProt
RGD
PMID:20421391 PMID:21572431 GO_REF:0000024 MGI:4456325 MGI:5004732 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051
JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in ISO (MGI:5461233|PMID:23241884) RGD PMID:23241884 MGI:5461233 NCBI chr 1:242,559,365...242,601,044
Ensembl chr 1:242,559,365...242,601,447
JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (MGI:3772713|PMID:18164222) RGD PMID:18164222 MGI:3772713 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rorc RAR-related orphan receptor C involved_in
acts_upstream_of_or_within
ISO (MGI:3692468|PMID:16990136), (MGI:3772713|PMID:18164222)
(MGI:3817792|PMID:18792410)
RGD PMID:16990136 PMID:18164222 PMID:18792410 MGI:3692468 MGI:3772713 MGI:3817792 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:3851267|PMID:19578362), (MGI:5448096|PMID:22983707)
UniProt
RGD
PMID:19578362 PMID:22983707 GO_REF:0000024 MGI:3851267 MGI:5448096 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051
JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO
GO_REF:0000024
(MGI:3692468|PMID:16990136), (MGI:6142555|PMID:27893700)
UniProt
RGD
PMID:16990136 PMID:27893700 GO_REF:0000024 MGI:3692468 MGI:6142555 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6142555|PMID:27893700)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:27893700 GO_REF:0000024 GO_REF:0000107 MGI:6142555 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Irf4 interferon regulatory factor 4 involved_in ISO (MGI:5448096|PMID:22983707) RGD PMID:22983707 MGI:5448096 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
JBrowse link
G Ly9 lymphocyte antigen 9 involved_in ISO (PMID:22184727) RGD PMID:22184727 NCBI chr13:84,081,283...84,100,757
Ensembl chr13:84,079,458...84,100,823
JBrowse link
G Otud5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO MGI:2386448|MGI:5752247 (MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:5621075 NCBI chr  X:14,626,173...14,659,331
Ensembl chr  X:14,626,164...14,659,573
JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO
IBA
(PMID:22184727)
PMID:21873635
RGD PMID:22184727 PMID:21873635 RGD:13792537 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5825383|PMID:28065600)
UniProt
RGD
PMID:28065600 GO_REF:0000024 MGI:5825383 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:4456325|PMID:20421391), (MGI:5004732|PMID:21572431)
UniProt
RGD
PMID:20421391 PMID:21572431 GO_REF:0000024 MGI:4456325 MGI:5004732 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051
JBrowse link
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO MGI:2158443 (MGI:3621346|PMID:16081776) RGD PMID:16081776 MGI:3621346 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:4838368|PMID:20706986) RGD PMID:20706986 MGI:4838368 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4838368|PMID:20706986)
RGD PMID:20706986 PMID:21873635 MGI:4838368, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856466 (MGI:61362|PMID:8434133) RGD PMID:8434133 MGI:61362 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:1673147) RGD PMID:1673147 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Ptger4 prostaglandin E receptor 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4353445|PMID:19465928)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19465928 GO_REF:0000024 GO_REF:0000107 MGI:4353445 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Rorc RAR-related orphan receptor C involved_in ISO (MGI:2686818|PMID:14691482) RGD PMID:14691482 MGI:2686818 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    immune system process 2852
      leukocyte activation 1079
        leukocyte activation involved in immune response 307
          lymphocyte activation involved in immune response 210
            T cell activation involved in immune response 116
              T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell + 9
              T cell differentiation involved in immune response + 79
              T cell proliferation involved in immune response + 5
              alpha-beta T cell activation involved in immune response + 73
              cytotoxic T cell degranulation + 4
              gamma-delta T cell activation involved in immune response + 0
Path 2
Term Annotations click to browse term
  biological_process 19541
    cellular process 18407
      cell activation 1223
        cell activation involved in immune response 311
          leukocyte activation involved in immune response 307
            lymphocyte activation involved in immune response 210
              T cell activation involved in immune response 116
                T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell + 9
                T cell differentiation involved in immune response + 79
                T cell proliferation involved in immune response + 5
                alpha-beta T cell activation involved in immune response + 73
                cytotoxic T cell degranulation + 4
                gamma-delta T cell activation involved in immune response + 0
paths to the root