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ONTOLOGY REPORT - ANNOTATIONS


Term:lymphocyte activation involved in immune response
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Accession:GO:0002285 term browser browse the term
Definition:A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: lymphocyte activation during immune response


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B cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnb1 interferon beta 1 involved_in ISO (PMID:12932356) UniProt PMID:12932356 NCBI chrNW_004936652:2,736,270...2,736,833 JBrowse link
B cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1927957|PMID:11120811)
(MGI:82358|PMID:8806812)
(MGI:76334|PMID:7671324)
MGI
Ensembl
PMID:7671324 PMID:8806812 PMID:11120811 GO_REF:0000107 MGI:1927957 MGI:76334 MGI:82358 NCBI chrNW_004936487:17,690,206...17,819,619 JBrowse link
G Cd180 CD180 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1860539|PMID:10880523) MGI
Ensembl
PMID:10880523 GO_REF:0000107 MGI:1860539 NCBI chrNW_004936480:2,105,179...2,119,137 JBrowse link
G Cd19 CD19 molecule involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936501:11,793,903...11,807,410 JBrowse link
G Gapt GRB2 binding adaptor protein, transmembrane acts_upstream_of_or_within ISO (MGI:3804359|PMID:18559951) MGI PMID:18559951 MGI:3804359 NCBI chrNW_004936480:9,644,447...9,644,920 JBrowse link
G Plcl2 phospholipase C like 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2677607|PMID:14517301) MGI
Ensembl
PMID:14517301 GO_REF:0000107 MGI:2677607 NCBI chrNW_004936473:9,628,612...9,801,713 JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1860539|PMID:10880523) MGI
Ensembl
PMID:10880523 GO_REF:0000107 MGI:1860539 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:18,825,969...18,833,179 JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3829555|PMID:17277142) MGI PMID:17277142 MGI:3829555 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3653524|PMID:11266473) MGI
Ensembl
PMID:11266473 GO_REF:0000107 MGI:3653524 NCBI chrNW_004936471:16,738,204...16,815,561 JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf8 interferon regulatory factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936641:2,608,109...2,622,446 JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2679743|PMID:12928432) MGI
Ensembl
PMID:12928432 GO_REF:0000107 MGI:2679743 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:1,852,759...1,870,647 JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (MGI:3619310|PMID:14607964) MGI PMID:14607964 MGI:3619310 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G Cdh17 cadherin 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936544:7,156,213...7,208,392 JBrowse link
G Il21 interleukin 21 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chrNW_004936662:1,689,879...1,696,883 JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Irf8 interferon regulatory factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936641:2,608,109...2,622,446 JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5547463|PMID:23997217) MGI
Ensembl
PMID:23997217 GO_REF:0000107 MGI:5547463 NCBI chrNW_004936606:3,144,616...3,158,825 JBrowse link
G Pou2af1 POU class 2 homeobox associating factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936612:3,032,015...3,055,015 JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:1,852,759...1,870,647 JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761960|PMID:17713479) MGI
Ensembl
PMID:17713479 GO_REF:0000107 MGI:3761960 NCBI chrNW_004936870:25,039...34,601 JBrowse link
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of
involved_in
ISO
IEA
(MGI:5763555|PMID:25404367) MGI
Ensembl
PMID:25404367 GO_REF:0000107 MGI:5763555 NCBI chrNW_004936538:2,815,370...2,877,084 JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:4,607,716...4,631,237 JBrowse link
G Cd40lg CD40 ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936513:10,607,617...10,620,403 JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3052883|PMID:15280420) MGI
Ensembl
PMID:15280420 GO_REF:0000107 MGI:3052883 NCBI chrNW_004936706:1,854,938...1,867,521 JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (MGI:3028407|PMID:14716311) MGI PMID:14716311 MGI:3028407 NCBI chrNW_004936526:8,570,488...8,627,004 JBrowse link
G Exosc3 exosome component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:5,580,855...5,586,170 JBrowse link
G Exosc6 exosome component 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:23,295,441...23,297,321 JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761960|PMID:17713479) MGI
Ensembl
PMID:17713479 GO_REF:0000107 MGI:3761960 NCBI chrNW_004936472:3,861,833...3,867,943 JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2662086|PMID:12743174) MGI
Ensembl
PMID:12743174 GO_REF:0000107 MGI:2662086 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2662086|PMID:12743174)
(MGI:1342394|PMID:10430621)
MGI
Ensembl
PMID:10430621 PMID:12743174 GO_REF:0000107 MGI:1342394 MGI:2662086 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3641510|PMID:16618598)
(MGI:3723381|PMID:17015724)
MGI
Ensembl
PMID:16618598 PMID:17015724 GO_REF:0000107 MGI:3641510 MGI:3723381 NCBI chrNW_004936508:4,708,661...4,728,671 JBrowse link
G Nbn nibrin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936544:3,773,828...3,812,673 JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chrNW_004936784:1,073,236...1,094,575 JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chrNW_004936476:22,074,146...22,121,286 JBrowse link
G Sanbr SANT and BTB domain regulator of CSR involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936491:6,578,538...6,629,610 JBrowse link
G Swap70 switching B cell complex subunit SWAP70 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1270060|PMID:9642267) MGI
Ensembl
PMID:9642267 GO_REF:0000107 MGI:1270060 NCBI chrNW_004936528:8,441,839...8,511,374 JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3723381|PMID:17015724) MGI
Ensembl
PMID:17015724 GO_REF:0000107 MGI:3723381 NCBI chrNW_004936769:911,296...922,770 JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (MGI:3761960|PMID:17713479) MGI PMID:17713479 MGI:3761960 NCBI chrNW_004936469:2,248,367...2,495,215 JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:16,669,297...16,689,451 JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of
involved_in
ISO
IEA
(MGI:1345885|PMID:10490661) MGI
Ensembl
PMID:10490661 GO_REF:0000107 MGI:1345885 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of
involved_in
ISO
IEA
(MGI:3695768|PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 MGI:3695768 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of
involved_in
ISO
IEA
(MGI:1345885|PMID:10490661) MGI
Ensembl
PMID:10490661 GO_REF:0000107 MGI:1345885 NCBI chrNW_004936646:1,297,530...1,312,508 JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chrNW_004936506:1,678,069...1,687,632 JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3 transcription coactivator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:85481|PMID:9009202) MGI
Ensembl
PMID:9009202 GO_REF:0000107 MGI:85481 NCBI chrNW_004936706:1,410,848...1,427,822 JBrowse link
G Cdh17 cadherin 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936544:7,156,213...7,208,392 JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004937098:212,704...220,589 JBrowse link
G Dock10 dedicator of cytokinesis 10 involved_in ISO (MGI:5818419|PMID:25729399) UniProt PMID:25729399 MGI:5818419 NCBI chrNW_004936569:6,274,747...6,462,265 JBrowse link
G Dock11 dedicator of cytokinesis 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:11,148,877...11,334,381 JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936823:283,207...290,970 JBrowse link
G LOC101965998 notch receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936872:454,273...539,544 JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:3,547,345...3,561,940 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936675:216,970...325,670 JBrowse link
mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr183 G protein-coupled receptor 183 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:11,196,567...11,198,890 JBrowse link
G Rag2 recombination activating 2 ISO RGD PMID:30206106 RGD:38508903 NCBI chrNW_004936533:1,801,207...1,807,431 JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:15,860,669...15,934,500 JBrowse link
memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsc1 TSC complex subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5608813|PMID:25271321) MGI
Ensembl
PMID:25271321 GO_REF:0000107 MGI:5608813 NCBI chrNW_004936487:19,331,183...19,386,841 JBrowse link
natural killer cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776)
(MGI:3773416|PMID:15905190)
UniProt PMID:11714776 PMID:15905190 MGI:3773416 NCBI chrNW_004936903:146,108...162,410 JBrowse link
G Il12b interleukin 12B ISO RGD PMID:14960310 RGD:1600048 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:12,338,542...12,344,236 JBrowse link
G LOC101955076 low affinity immunoglobulin gamma Fc region receptor III-A involved_in ISO (PMID:25786175), (PMID:28652325) UniProt PMID:25786175 PMID:28652325 NCBI chrNW_004937131:42,523...49,533 JBrowse link
G Nkg7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608), (MGI:6810811|PMID:33911019) UniProt PMID:32839608 PMID:33911019 MGI:6506882 MGI:6810811 NCBI chrNW_004937378:42,083...43,068 JBrowse link
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3653524|PMID:11266473) MGI
Ensembl
PMID:11266473 GO_REF:0000107 MGI:3653524 NCBI chrNW_004936471:16,738,204...16,815,561 JBrowse link
G Unc13d unc-13 homolog D acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3703574|PMID:17420270) MGI
Ensembl
PMID:17420270 GO_REF:0000107 MGI:3703574 NCBI chrNW_004936594:1,008,215...1,023,023 JBrowse link
G Vamp2 vesicle associated membrane protein 2 NOT|involved_in ISO (PMID:18042464) UniProt PMID:18042464 NCBI chrNW_004936595:1,385,692...1,389,484 JBrowse link
G Vamp7 vesicle associated membrane protein 7 involved_in ISO (PMID:18042464) UniProt PMID:18042464 NCBI chrNW_004936958:345,055...393,384 JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101954488 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:11,683,330...11,734,423 JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly(ADP-ribose) polymerase family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:3,291,282...3,297,581 JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thoc1 THO complex 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936550:590,119...638,152 JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1345885|PMID:10490661) MGI
Ensembl
PMID:10490661 GO_REF:0000107 MGI:1345885 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695768|PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 MGI:3695768 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (MGI:3694584|PMID:17137798) MGI PMID:17137798 MGI:3694584 NCBI chrNW_004936504:12,053,470...12,103,346 JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen like 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6188369|PMID:29341118) MGI
Ensembl
PMID:29341118 GO_REF:0000107 MGI:6188369 NCBI chrNW_004936479:20,619,955...20,625,416 JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) UniProt PMID:23408620 MGI:5491117 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101970371 peptidoglycan recognition protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:3,184,904...3,197,203 JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5297102|PMID:20709292) MGI
Ensembl
PMID:20709292 GO_REF:0000107 MGI:5297102 NCBI chrNW_004936706:2,317,137...2,320,993 JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5297102|PMID:20709292) MGI
Ensembl
PMID:20709292 GO_REF:0000107 MGI:5297102 NCBI chrNW_004936596:5,038,452...5,043,172 JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3051167|PMID:15240705) MGI
Ensembl
PMID:15240705 GO_REF:0000107 MGI:3051167 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
G LOC101964865 complement receptor type 1 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:26492563) UniProt PMID:26492563 NCBI chrNW_004936515:6,001,324...6,015,407 JBrowse link
G Lgals3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chrNW_004936697:20,861...38,568 JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 NCBI chrNW_004936501:11,025,590...11,058,807 JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chrNW_004936596:3,212,593...3,224,426 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Il2 interleukin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:13,919,006...13,973,868 JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:11,341,663...11,393,275 JBrowse link
G Smad7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:13,894,586...13,921,978 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:13,546,405...13,558,635 JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5450776|PMID:23034280) MGI
Ensembl
PMID:23034280 GO_REF:0000107 MGI:5450776 NCBI chrNW_004936580:4,546,139...4,560,157 JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:19,714,145...19,722,512 JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936556:745,798...765,926 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:13,546,405...13,558,635 JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:14,499,495...14,508,074 JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:9,124,314...9,142,372 JBrowse link
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2450484|PMID:12594267) MGI
Ensembl
PMID:12594267 GO_REF:0000107 MGI:2450484 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chrNW_004936650:1,416,825...1,422,595 JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:5,531,002...5,588,022 JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3580753|PMID:15917799) MGI
Ensembl
PMID:15917799 GO_REF:0000107 MGI:3580753 NCBI chrNW_004936481:13,919,006...13,973,868 JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of
involved_in
ISO
IEA
(MGI:3051167|PMID:15240705) MGI
Ensembl
PMID:15240705 GO_REF:0000107 MGI:3051167 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:6407632|PMID:29259245) MGI PMID:29259245 MGI:6407632 NCBI chrNW_004937067:194,375...246,607 JBrowse link
G Itm2a integral membrane protein 2A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5613782|PMID:24831988) MGI
Ensembl
PMID:24831988 GO_REF:0000107 MGI:5613782 NCBI chrNW_004936547:1,260,705...1,267,443 JBrowse link
G Lgals1 galectin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5301217|PMID:21753146) MGI
Ensembl
PMID:21753146 GO_REF:0000107 MGI:5301217 NCBI chrNW_004936492:3,407,704...3,411,197 JBrowse link
G Lgals8 galectin 8 acts_upstream_of_or_within ISO (MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:5301217 NCBI chrNW_004936484:16,357,433...16,374,675 JBrowse link
G Nkx2-3 NK2 homeobox 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1888604|PMID:10926756) MGI
Ensembl
PMID:10926756 GO_REF:0000107 MGI:1888604 NCBI chrNW_004936636:529,669...532,237 JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5009766|PMID:21255825) MGI
Ensembl
PMID:21255825 GO_REF:0000107 MGI:5009766 NCBI chrNW_004936524:5,580,855...5,586,170 JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5009766|PMID:21255825) MGI
Ensembl
PMID:21255825 GO_REF:0000107 MGI:5009766 NCBI chrNW_004936475:23,295,441...23,297,321 JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936798:261,566...284,480 JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:1,928,172...1,983,983 JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936886:596,949...602,959 JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:538,703...542,901 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:9,440,129...9,488,215 JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:26,045,500...26,105,980 JBrowse link
G Shld1 shieldin complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:13,179,218...13,267,980 JBrowse link
G Shld2 shieldin complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:5,315,297...5,400,752 JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893
G Tfrc transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936784:696,738...728,385 JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:6,589,395...6,668,242 JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5462481|PMID:23241889) MGI
Ensembl
PMID:23241889 GO_REF:0000107 MGI:5462481 NCBI chrNW_004936477:21,460,442...21,531,563 JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004936750:439,396...468,747 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within
involved_in
ISO
ISS
(PMID:14988498) MGI
AgBase
PMID:14988498 GO_REF:0000024 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3037416|PMID:14988498)
(PMID:14988498)
MGI
Ensembl
PMID:14988498 GO_REF:0000107 MGI:3037416 NCBI chrNW_004936595:839,877...842,962 JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin like cytokine factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:2,372,889...2,376,316 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1345885|PMID:10490661) MGI
Ensembl
PMID:10490661 GO_REF:0000107 MGI:1345885 NCBI chrNW_004936646:1,297,530...1,312,508 JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5763555|PMID:25404367) MGI
Ensembl
PMID:25404367 GO_REF:0000107 MGI:5763555 NCBI chrNW_004936538:2,815,370...2,877,084 JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:62368|PMID:7688139) MGI
Ensembl
PMID:7688139 GO_REF:0000107 MGI:62368 NCBI chrNW_004936631:335,411...363,407 JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2670820|PMID:12882831) MGI
Ensembl
PMID:12882831 GO_REF:0000107 MGI:2670820 NCBI chrNW_004936514:6,936,915...6,947,246 JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) MGI PMID:12882831 MGI:2670820 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:87443|PMID:1830926) MGI
Ensembl
PMID:1830926 GO_REF:0000107 MGI:87443 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004936501:12,657,092...12,660,106 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:9,440,129...9,488,215 JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004936750:439,396...468,747 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:85031|PMID:9015183) MGI
Ensembl
PMID:9015183 GO_REF:0000107 MGI:85031 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2670820|PMID:12882831) MGI
Ensembl
PMID:12882831 GO_REF:0000107 MGI:2670820 NCBI chrNW_004936490:13,546,405...13,558,635 JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:743,630...745,998 JBrowse link
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:540,225...544,968 JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936530:361,872...367,005 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) BHF-UCL PMID:18713990 MGI:3806904 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:21,983,248...22,063,133 JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) UniProt PMID:19109136 NCBI chrNW_004936867:478,625...485,905 JBrowse link
G Lamp1 lysosomal associated membrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:377,359...389,121 JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 acts_upstream_of
involved_in
ISO
IEA
(PMID:22962438) ARUK-UCL
Ensembl
PMID:22962438 GO_REF:0000107 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il2 interleukin 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:22962438) ARUK-UCL
Ensembl
PMID:22962438 GO_REF:0000107 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Xbp1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936657:2,891,171...2,895,409 JBrowse link
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936794:664,089...670,294 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
G LOC101959667 HLA class II histocompatibility antigen, DM beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,846,653...25,852,006 JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:9,124,314...9,142,372 JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:3576832 NCBI chrNW_004936524:2,765,271...2,767,259 JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chrNW_004936650:1,416,825...1,422,595 JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2176424|PMID:11894097) MGI
Ensembl
PMID:11894097 GO_REF:0000107 MGI:2176424 NCBI chrNW_004936544:3,606,925...3,653,248 JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:5,531,002...5,588,022 JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:5,854,361...5,910,719 JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004936570:464,513...471,333 JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936630:1,601,006...1,633,844 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936864:709,693...732,119 JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:743,630...745,998 JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936612:2,306,963...2,325,086 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 NCBI chrNW_004936501:11,025,590...11,058,807 JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936864:709,693...732,119 JBrowse link
G Prkcz protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936737:1,303,502...1,383,135 JBrowse link
G Rara retinoic acid receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:15,376,217...15,420,638 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) BHF-UCL PMID:18354165 MGI:4943387 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myb MYB proto-oncogene, transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936560:2,797,943...2,828,813 JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5617929|PMID:24645804) MGI
Ensembl
PMID:24645804 GO_REF:0000107 MGI:5617929 NCBI chrNW_004936524:5,698,101...5,832,801 JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4887518|PMID:21211721) MGI
Ensembl
PMID:21211721 GO_REF:0000107 MGI:4887518 NCBI chrNW_004936491:12,857,928...12,961,709 JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:4,878,645...4,910,613 JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695768|PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 MGI:3695768 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1926579|PMID:11057672) MGI
Ensembl
PMID:11057672 GO_REF:0000107 MGI:1926579 NCBI chrNW_004936659:2,706,037...2,720,486 JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (MGI:3694584|PMID:17137798) MGI PMID:17137798 MGI:3694584 NCBI chrNW_004936504:12,053,470...12,103,346 JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:5649169|PMID:25310967) UniProt PMID:25310967 MGI:5649169 NCBI chrNW_004936660:481,772...493,567 JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3051162|PMID:15240675) MGI
Ensembl
PMID:15240675 GO_REF:0000107 MGI:3051162 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Znf683 zinc finger protein 683 involved_in ISO (MGI:5437828|PMID:22885984) UniProt PMID:22885984 MGI:5437828 NCBI chrNW_004936474:10,851,249...10,859,092 JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il27 interleukin 27 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:11,972,715...11,978,152 JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chrNW_004936525:8,238,128...8,240,974 JBrowse link
G Ccr6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chrNW_004936489:16,669,297...16,689,451 JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:540,225...544,968 JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chrNW_004936580:4,546,139...4,560,157 JBrowse link
T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1c CD1c molecule involved_in ISO (PMID:21167756) UniProt PMID:21167756 NCBI chrNW_004936740:2,068,558...2,071,531 JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (MGI:5544501|PMID:24310610) UniProt PMID:24310610 MGI:5544501 NCBI chrNW_004936471:3,423,792...3,527,089 JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936549:142,281...153,575 JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936857:646,363...726,338 JBrowse link
G Mdk midkine involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:2,687,825...2,690,292 JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3760494|PMID:17698590) MGI
Ensembl
PMID:17698590 GO_REF:0000107 MGI:3760494 NCBI chrNW_004936488:2,464,623...2,528,807 JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:3760494 NCBI chrNW_004936526:3,584,194...3,611,719 JBrowse link
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen like 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6188369|PMID:29341118) MGI
Ensembl
PMID:29341118 GO_REF:0000107 MGI:6188369 NCBI chrNW_004936479:20,619,955...20,625,416 JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G Itgal integrin subunit alpha L involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:12,921,509...12,966,791 JBrowse link
G LOC101974727 amyloid beta precursor protein binding family B member 1 interacting protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3714085|PMID:17403904) MGI
Ensembl
PMID:17403904 GO_REF:0000107 MGI:3714085 NCBI chrNW_004936484:1,909,547...2,009,596 JBrowse link
T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec4d C-type lectin domain family 4 member D acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5525050|PMID:23602766) MGI
Ensembl
PMID:23602766 GO_REF:0000107 MGI:5525050 NCBI chrNW_004936858:303,639...312,092 JBrowse link
G Clec4e C-type lectin domain family 4 member E acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5525050|PMID:23602766) MGI
Ensembl
PMID:23602766 GO_REF:0000107 MGI:5525050 NCBI chrNW_004936858:316,954...321,668 JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (MGI:5525050|PMID:23602766) MGI PMID:23602766 MGI:5525050 NCBI chrNW_004936903:514,278...517,975 JBrowse link
G Sema4a semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:5,404,380...5,431,183 JBrowse link
T cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule ISO RGD PMID:20500684 RGD:4892204 NCBI chrNW_004936536:8,414,491...8,481,712 JBrowse link
G Rps6 ribosomal protein S6 acts_upstream_of_or_within ISO (MGI:3610868|PMID:16357222) MGI PMID:16357222 MGI:3610868 NCBI chrNW_004936652:1,252,986...1,255,987 JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:86848|PMID:9176118) MGI
Ensembl
PMID:9176118 GO_REF:0000107 MGI:86848 NCBI chrNW_004936569:888,309...895,991 JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936481:14,499,495...14,508,074 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3610868|PMID:16357222) MGI
Ensembl
PMID:16357222 GO_REF:0000107 MGI:3610868 NCBI chrNW_004936595:919,807...935,367 JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 involved_in ISO (MGI:5607369|PMID:24859450) UniProt PMID:24859450 MGI:5607369 NCBI chrNW_004936603:2,631,781...3,146,104 JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:11,196,567...11,198,890 JBrowse link
G Il21 interleukin 21 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chrNW_004936662:1,689,879...1,696,883 JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5486592|PMID:23583643) MGI
Ensembl
PMID:23583643 GO_REF:0000107 MGI:5486592 NCBI chrNW_004936481:13,919,006...13,973,868 JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5486592|PMID:23583643) MGI
Ensembl
PMID:23583643 GO_REF:0000107 MGI:5486592 NCBI chrNW_004936487:11,341,663...11,393,275 JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cracr2a calcium release activated channel regulator 2A involved_in ISO (PMID:29987160)
(MGI:6195365|PMID:29987160)
UniProt PMID:29987160 MGI:6195365 NCBI chrNW_004936606:3,880,214...3,970,278 JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chrNW_004936650:1,416,825...1,422,595 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:15944249) UniProt PMID:15944249 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Il18r1 interleukin 18 receptor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2136797|PMID:10227969) MGI
Ensembl
PMID:10227969 GO_REF:0000107 MGI:2136797 NCBI chrNW_004936713:1,038,985...1,075,770 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 NCBI chrNW_004936501:11,025,590...11,058,807 JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936818:453,635...569,194 JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3621346|PMID:16081776) MGI
Ensembl
PMID:16081776 GO_REF:0000107 MGI:3621346 NCBI chrNW_004936706:1,569,603...1,596,831 JBrowse link
G Sema4a semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:5,404,380...5,431,183 JBrowse link
G Tmem98 transmembrane protein 98 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:2,065,663...2,074,678 JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:158,376...282,310 JBrowse link
G Spn sialophorin involved_in ISO (PMID:18036228) UniProt PMID:18036228 NCBI chrNW_004936501:12,773,967...12,776,642 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4838368|PMID:20706986) MGI
Ensembl
PMID:20706986 GO_REF:0000107 MGI:4838368 NCBI chrNW_004936646:1,297,530...1,312,508 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:13,546,405...13,558,635 JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:4,607,716...4,631,237 JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936636:406,389...446,167 JBrowse link
G Rora RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:21,402,056...21,567,908 JBrowse link
G Rorc RAR related orphan receptor C acts_upstream_of_or_within
involved_in
ISO (MGI:3817792|PMID:18792410)
(MGI:3692468|PMID:16990136), (MGI:3772713|PMID:18164222)
MGI
GO_Central
PMID:16990136 PMID:18164222 PMID:18792410 MGI:3692468 MGI:3772713 MGI:3817792 NCBI chrNW_004936580:1,997,640...2,020,649 JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:4,607,716...4,631,237 JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:6142555|PMID:27893700)
(MGI:3692468|PMID:16990136)
UniProt PMID:16990136 PMID:27893700 MGI:3692468 MGI:6142555 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Il6r interleukin 6 receptor involved_in ISO (MGI:6142555|PMID:27893700) UniProt PMID:27893700 MGI:6142555 NCBI chrNW_004936580:4,055,438...4,081,876 JBrowse link
G Irf4 interferon regulatory factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936633:1,565,293...1,580,859 JBrowse link
G Otud5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO (MGI:5621075|PMID:25470037) MGI PMID:25470037 MGI:5621075 NCBI chrNW_004936721:847,360...876,912 JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:22184727) UniProt PMID:22184727 NCBI chrNW_004936740:155,268...165,536 JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:17,119,189...17,178,402 JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:4,607,716...4,631,237 JBrowse link
G Bcl3 BCL3 transcription coactivator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3621346|PMID:16081776) MGI
Ensembl
PMID:16081776 GO_REF:0000107 MGI:3621346 NCBI chrNW_004936706:1,410,848...1,427,822 JBrowse link
G Bcl6 BCL6 transcription repressor acts_upstream_of
involved_in
ISO
IEA
(MGI:2450484|PMID:12594267) MGI
Ensembl
PMID:12594267 GO_REF:0000107 MGI:2450484 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4838368|PMID:20706986) MGI
Ensembl
PMID:20706986 GO_REF:0000107 MGI:4838368 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chrNW_004936650:1,416,825...1,422,595 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 NCBI chrNW_004936501:11,025,590...11,058,807 JBrowse link
G Il6 interleukin 6 acts_upstream_of ISO (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO (MGI:61362|PMID:8434133) MGI PMID:8434133 MGI:61362 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
G Il12b interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
G Ptger4 prostaglandin E receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
G Rorc RAR related orphan receptor C involved_in ISO (MGI:2686818|PMID:14691482) UniProt PMID:14691482 MGI:2686818 NCBI chrNW_004936580:1,997,640...2,020,649 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14983
    immune system process 2163
      leukocyte activation 868
        lymphocyte activation 707
          lymphocyte activation involved in immune response 183
            B cell activation involved in immune response + 90
            T cell activation involved in immune response + 92
            natural killer cell activation involved in immune response + 17
Path 2
Term Annotations click to browse term
  biological_process 14983
    cellular process 13972
      cell activation 997
        cell activation involved in immune response 270
          leukocyte activation involved in immune response 266
            lymphocyte activation involved in immune response 183
              B cell activation involved in immune response + 90
              T cell activation involved in immune response + 92
              natural killer cell activation involved in immune response + 17
paths to the root