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ONTOLOGY REPORT - ANNOTATIONS


Term:lymphocyte activation involved in immune response
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Accession:GO:0002285 term browser browse the term
Definition:A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: lymphocyte activation during immune response



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B cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNB1 interferon beta 1 involved_in ISO (PMID:12932356) UniProt PMID:12932356 NCBI chr 9:20,884,742...20,886,317 JBrowse link
B cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:82358|PMID:8806812)
(MGI:1927957|PMID:11120811)
(MGI:76334|PMID:7671324)
MGI
Ensembl
PMID:7671324 PMID:8806812 PMID:11120811 GO_REF:0000107 MGI:1927957 MGI:76334 MGI:82358 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941
JBrowse link
G CD180 CD180 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1860539|PMID:10880523) MGI
Ensembl
PMID:10880523 GO_REF:0000107 MGI:1860539 NCBI chr 5:46,799,607...46,815,214
Ensembl chr 5:48,364,874...48,381,694
JBrowse link
G CD19 CD19 molecule involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 Ensembl chr16:29,320,734...29,327,481 JBrowse link
G GAPT GRB2 binding adaptor protein, transmembrane acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3804359|PMID:18559951) MGI
Ensembl
PMID:18559951 GO_REF:0000107 MGI:3804359 NCBI chr 5:55,509,317...55,510,711
Ensembl chr 5:57,144,608...57,145,081
JBrowse link
G PLCL2 phospholipase C like 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2677607|PMID:14517301) MGI
Ensembl
PMID:14517301 GO_REF:0000107 MGI:2677607 NCBI chr 3:16,736,430...17,015,531
Ensembl chr 3:17,154,500...17,351,287
JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1860539|PMID:10880523) MGI
Ensembl
PMID:10880523 GO_REF:0000107 MGI:1860539 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:27,601,829...27,608,701
Ensembl chr 3:27,925,086...27,930,274
JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:3829555|PMID:17277142) MGI PMID:17277142 MGI:3829555 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB27A RAB27A, member RAS oncogene family acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3653524|PMID:11266473) MGI
Ensembl
PMID:11266473 GO_REF:0000107 MGI:3653524 NCBI chr15:34,174,491...34,263,045
Ensembl chr15:52,498,202...52,529,984
JBrowse link
G STX11 syntaxin 11 acts_upstream_of_or_within ISO (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) MGI PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 6:141,924,656...141,974,579
Ensembl chr 6:146,688,670...146,689,533
JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF8 interferon regulatory factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,568,370...66,591,949
Ensembl chr16:85,905,334...85,929,073
JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2679743|PMID:12928432) MGI
Ensembl
PMID:12928432 GO_REF:0000107 MGI:2679743 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259
JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3619310|PMID:14607964) MGI
Ensembl
PMID:14607964 GO_REF:0000107 MGI:3619310 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868
JBrowse link
G CDH17 cadherin 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:90,750,904...90,818,629
Ensembl chr 8:92,696,182...92,760,732
JBrowse link
G IL21 interleukin 21 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IRF8 interferon regulatory factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,568,370...66,591,949
Ensembl chr16:85,905,334...85,929,073
JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5547463|PMID:23997217) MGI
Ensembl
PMID:23997217 GO_REF:0000107 MGI:5547463 NCBI chr12:2,933,227...2,980,509
Ensembl chr12:2,865,297...2,877,555
JBrowse link
G POU2AF1 POU class 2 homeobox associating factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:106,231,870...106,258,822
Ensembl chr11:110,078,850...110,103,996
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259
JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase involved_in
acts_upstream_of_or_within
ISO (MGI:5004983|PMID:21518874)
(MGI:3761960|PMID:17713479)
UniProt
MGI
PMID:17713479 PMID:21518874 MGI:3761960 MGI:5004983 NCBI chr12:8,688,392...8,699,008
Ensembl chr12:8,904,273...8,913,917
JBrowse link
G ATAD5 ATPase family AAA domain containing 5 acts_upstream_of
involved_in
ISO
IEA
(MGI:5763555|PMID:25404367) MGI
Ensembl
PMID:25404367 GO_REF:0000107 MGI:5763555 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242
JBrowse link
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,075,768...56,100,749
Ensembl chr14:74,919,115...74,943,652
JBrowse link
G CD40LG CD40 ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:125,776,138...125,788,820
Ensembl chr  X:136,042,849...136,058,202
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3052883|PMID:15280420) MGI
Ensembl
PMID:15280420 GO_REF:0000107 MGI:3052883 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430
JBrowse link
G EXO1 exonuclease 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3028407|PMID:14716311) MGI
Ensembl
PMID:14716311 GO_REF:0000107 MGI:3028407 NCBI chr 1:217,410,175...217,451,982
Ensembl chr 1:222,389,684...222,431,556
JBrowse link
G EXOSC3 exosome component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:37,611,173...37,634,869
Ensembl chr 9:38,552,659...38,558,078
JBrowse link
G LIG4 DNA ligase 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761960|PMID:17713479) MGI
Ensembl
PMID:17713479 GO_REF:0000107 MGI:3761960 NCBI chr13:89,336,434...89,347,418
Ensembl chr13:108,475,820...108,478,555
JBrowse link
G LOC100970806 exosome complex component MTR3 involved_in ISO (MGI:5009766|PMID:21255825) UniProt PMID:21255825 MGI:5009766 NCBI chr 7:140,163,275...140,176,732 JBrowse link
G MLH1 mutL homolog 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2662086|PMID:12743174) MGI
Ensembl
PMID:12743174 GO_REF:0000107 MGI:2662086 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MSH2 mutS homolog 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1342394|PMID:10430621)
(MGI:2662086|PMID:12743174)
MGI
Ensembl
PMID:10430621 PMID:12743174 GO_REF:0000107 MGI:1342394 MGI:2662086 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G MSH6 mutS homolog 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3723381|PMID:17015724)
(MGI:3641510|PMID:16618598)
MGI
Ensembl
PMID:16618598 PMID:17015724 GO_REF:0000107 MGI:3641510 MGI:3723381 NCBI chr2A:47,901,591...47,926,662
Ensembl chr2A:48,824,350...48,849,779
JBrowse link
G NBN nibrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307
JBrowse link
G RNF168 ring finger protein 168 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chr 3:193,814,785...193,848,620
Ensembl chr 3:203,756,589...203,790,687
JBrowse link
G RNF8 ring finger protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,918,705...36,955,380
Ensembl chr 6:38,108,414...38,145,949
JBrowse link
G SANBR SANT and BTB domain regulator of CSR involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:61,157,551...61,229,955
Ensembl chr2A:62,299,121...62,369,817
JBrowse link
G SWAP70 switching B cell complex subunit SWAP70 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1270060|PMID:9642267) MGI
Ensembl
PMID:9642267 GO_REF:0000107 MGI:1270060 NCBI chr11:9,797,024...9,883,400
Ensembl chr11:9,526,752...9,614,422
JBrowse link
G UNG uracil DNA glycosylase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3723381|PMID:17015724) MGI
Ensembl
PMID:17015724 GO_REF:0000107 MGI:3723381 NCBI chr12:106,674,073...106,687,054
Ensembl chr12:110,067,879...110,080,891
JBrowse link
G XRCC4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (MGI:3761960|PMID:17713479) MGI PMID:17713479 MGI:3761960 NCBI chr 5:31,927,463...32,202,394
Ensembl chr 5:32,246,320...32,521,490
JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR6 C-C motif chemokine receptor 6 involved_in ISO (MGI:5787846|PMID:27174992) UniProt PMID:27174992 MGI:5787846 NCBI chr 6:165,094,563...165,109,774
Ensembl chr 6:170,069,689...170,084,779
JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of
involved_in
ISO
IEA
(MGI:1345885|PMID:10490661) MGI
Ensembl
PMID:10490661 GO_REF:0000107 MGI:1345885 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of
involved_in
ISO
IEA
(MGI:3695768|PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 MGI:3695768 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G IL4 interleukin 4 acts_upstream_of ISO (MGI:3037416|PMID:14988498) MGI PMID:14988498 MGI:3037416 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:84,729,615...84,743,352
Ensembl chr2B:202,623,497...202,636,959
JBrowse link
G IL4 interleukin 4 acts_upstream_of ISO (MGI:3037416|PMID:14988498) MGI PMID:14988498 MGI:3037416 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL3 BCL3 transcription coactivator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:85481|PMID:9009202) MGI
Ensembl
PMID:9009202 GO_REF:0000107 MGI:85481 NCBI chr19:41,696,162...41,708,485
Ensembl chr19:50,304,171...50,313,005
JBrowse link
G CDH17 cadherin 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:90,750,904...90,818,629
Ensembl chr 8:92,696,182...92,760,732
JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759
JBrowse link
G DOCK10 dedicator of cytokinesis 10 involved_in ISO (MGI:5818419|PMID:25729399) UniProt PMID:25729399 MGI:5818419 NCBI chr2B:112,006,479...112,283,939
Ensembl chr2B:230,578,452...230,854,877
JBrowse link
G DOCK11 dedicator of cytokinesis 11 involved_in ISO (MGI:5818419|PMID:25729399) UniProt PMID:25729399 MGI:5818419 NCBI chr  X:107,502,955...107,694,069
Ensembl chr  X:117,952,995...118,161,009
JBrowse link
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISO (MGI:3838059|PMID:19217325) UniProt PMID:19217325 MGI:3838059 NCBI chr 7:2,781,493...2,790,936 JBrowse link
G MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:18,385,664...18,407,056
Ensembl chr22:36,218,403...36,239,804
JBrowse link
G NOTCH2 notch receptor 2 involved_in ISO (MGI:3838059|PMID:19217325) UniProt PMID:19217325 MGI:3838059 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840
JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C17H17orf99 chromosome 17 C17orf99 homolog involved_in ISO (MGI:6103709|PMID:28978694) UniProt PMID:28978694 MGI:6103709 NCBI chr17:72,223,073...72,244,049
Ensembl chr17:77,776,151...77,796,139
JBrowse link
G GPR183 G protein-coupled receptor 183 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:80,461,908...80,475,046
Ensembl chr13:99,601,220...99,602,305
JBrowse link
G RAG2 recombination activating 2 ISO RGD PMID:30206106 RGD:38508903 NCBI chr11:36,558,419...36,564,997
Ensembl chr11:36,431,703...36,433,286
JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (MGI:2387354|PMID:10755614) UniProt PMID:10755614 MGI:2387354 NCBI chr 8:130,111,085...130,227,195
Ensembl chr 8:133,084,835...133,119,791
JBrowse link
memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSC1 TSC complex subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5608813|PMID:25271321) MGI
Ensembl
PMID:25271321 GO_REF:0000107 MGI:5608813 NCBI chr 9:104,007,708...104,060,938
Ensembl chr 9:132,638,003...132,675,759
JBrowse link
natural killer cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD244 CD244 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:136,186,906...136,219,669
Ensembl chr 1:140,110,808...140,123,065
JBrowse link
G IFNA8 interferon alpha 8 acts_upstream_of_or_within ISO (MGI:3828876|PMID:19130550) MGI PMID:19130550 MGI:3828876 NCBI chr 9:21,269,864...21,270,920
Ensembl chr 9:21,887,457...21,888,026
JBrowse link
G IL12B interleukin 12B ISO RGD PMID:14960310 RGD:1600048 NCBI chr 5:154,706,467...154,722,231
Ensembl chr 5:161,325,303...161,335,381
JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,550,383...30,556,196 JBrowse link
G NKG7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608), (MGI:6810811|PMID:33911019) UniProt PMID:32839608 PMID:33911019 MGI:6506882 MGI:6810811 NCBI chr19:48,306,714...48,307,961
Ensembl chr19:57,192,788...57,193,882
JBrowse link
G RAB27A RAB27A, member RAS oncogene family acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3653524|PMID:11266473) MGI
Ensembl
PMID:11266473 GO_REF:0000107 MGI:3653524 NCBI chr15:34,174,491...34,263,045
Ensembl chr15:52,498,202...52,529,984
JBrowse link
G STX11 syntaxin 11 acts_upstream_of_or_within ISO (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) MGI PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 6:141,924,656...141,974,579
Ensembl chr 6:146,688,670...146,689,533
JBrowse link
G UNC13D unc-13 homolog D acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3703574|PMID:17420270) MGI
Ensembl
PMID:17420270 GO_REF:0000107 MGI:3703574 NCBI chr17:69,777,570...69,794,877
Ensembl chr17:75,328,572...75,344,842
JBrowse link
G VAMP2 vesicle associated membrane protein 2 NOT|involved_in ISO (PMID:18042464) UniProt PMID:18042464 NCBI chr17:43,495,464...43,499,348
Ensembl chr17:48,228,253...48,231,948
JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in ISO (PMID:18042464) UniProt PMID:18042464 NCBI chr  X:145,362,432...145,425,097
Ensembl chr  X:155,257,185...155,320,215
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881
JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G THOC1 THO complex 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:14,052,858...14,102,559
Ensembl chr18:17,692,797...17,742,570
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1345885|PMID:10490661) MGI
Ensembl
PMID:10490661 GO_REF:0000107 MGI:1345885 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695768|PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 MGI:3695768 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3694584|PMID:17137798) MGI
Ensembl
PMID:17137798 GO_REF:0000107 MGI:3694584 NCBI chr 5:137,467,161...137,511,569
Ensembl chr 5:143,600,789...143,622,913
JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGL2 fibrinogen like 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6188369|PMID:29341118) MGI
Ensembl
PMID:29341118 GO_REF:0000107 MGI:6188369 NCBI chr 7:69,114,082...69,120,575
Ensembl chr 7:82,926,266...82,932,550
JBrowse link
G LOC100976419 interferon lambda-1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:36,394,462...36,397,363
Ensembl chr19:44,942,186...44,944,519
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LGALS9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) UniProt PMID:23408620 MGI:5491117 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959
JBrowse link
G LOC100978457 patr class I histocompatibility antigen, CH28 alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:29,523,929...29,529,385
Ensembl chr 6:30,181,133...30,186,082
JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGLYRP1 peptidoglycan recognition protein 1 acts_upstream_of_or_within ISO (MGI:5297102|PMID:20709292) MGI PMID:20709292 MGI:5297102 NCBI chr19:43,033,080...43,037,726
Ensembl chr19:51,569,275...51,573,764
JBrowse link
G PGLYRP2 peptidoglycan recognition protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5297102|PMID:20709292) MGI
Ensembl
PMID:20709292 GO_REF:0000107 MGI:5297102 NCBI chr19:14,999,893...15,012,376
Ensembl chr19:15,986,090...15,997,726
JBrowse link
G PGLYRP3 peptidoglycan recognition protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5297102|PMID:20709292) MGI
Ensembl
PMID:20709292 GO_REF:0000107 MGI:5297102 NCBI chr 1:128,642,034...128,656,082
Ensembl chr 1:132,270,957...132,283,860
JBrowse link
G PGLYRP4 peptidoglycan recognition protein 4 acts_upstream_of_or_within ISO (MGI:5297102|PMID:20709292) MGI PMID:20709292 MGI:5297102 NCBI chr 1:128,681,726...128,700,275
Ensembl chr 1:132,310,256...132,329,013
JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3051167|PMID:15240705) MGI
Ensembl
PMID:15240705 GO_REF:0000107 MGI:3051167 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 1:183,094,601...183,246,957 JBrowse link
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:152,486,125...152,514,004
Ensembl chr 5:159,108,915...159,131,007
JBrowse link
G LGALS3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chr14:35,715,850...35,732,263
Ensembl chr14:53,990,023...54,006,412
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G JAK3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chr19:17,299,129...17,330,700
Ensembl chr19:18,283,560...18,300,964
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G IL2 interleukin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:3817792|PMID:18792410) MGI PMID:18792410 MGI:3817792 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:93,975,164...94,031,516
Ensembl chr 9:122,313,791...122,365,102
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chr18:42,306,324...42,337,214 JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5450776|PMID:23034280) MGI
Ensembl
PMID:23034280 GO_REF:0000107 MGI:5450776 NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOXL3 lysyl oxidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,598,870...74,622,502
Ensembl chr2A:76,105,957...76,128,495
JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chr 1:148,528,535...148,662,839
Ensembl chr 1:152,251,683...152,262,668
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2450484|PMID:12594267) MGI
Ensembl
PMID:12594267 GO_REF:0000107 MGI:2450484 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) UniProt PMID:12242343 MGI:3687909 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041
JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RC3H1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3580753|PMID:15917799) MGI
Ensembl
PMID:15917799 GO_REF:0000107 MGI:3580753 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of
involved_in
ISO
IEA
(MGI:3051167|PMID:15240705) MGI
Ensembl
PMID:15240705 GO_REF:0000107 MGI:3051167 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:6407632|PMID:29259245) MGI PMID:29259245 MGI:6407632 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
JBrowse link
G ITM2A integral membrane protein 2A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5613782|PMID:24831988) MGI
Ensembl
PMID:24831988 GO_REF:0000107 MGI:5613782 NCBI chr  X:68,475,114...68,482,274
Ensembl chr  X:78,585,836...78,593,037
JBrowse link
G LGALS1 galectin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5301217|PMID:21753146) MGI
Ensembl
PMID:21753146 GO_REF:0000107 MGI:5301217 NCBI chr22:18,593,154...18,597,432
Ensembl chr22:36,426,228...36,430,356
JBrowse link
G LGALS8 galectin 8 acts_upstream_of_or_within ISO (MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:5301217 NCBI chr 1:212,083,584...212,112,182 JBrowse link
G NKX2-3 NK2 homeobox 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1888604|PMID:10926756) MGI
Ensembl
PMID:10926756 GO_REF:0000107 MGI:1888604 NCBI chr10:96,146,636...96,150,238 JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G LGALS9 galectin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959
JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXOSC3 exosome component 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5009766|PMID:21255825) MGI
Ensembl
PMID:21255825 GO_REF:0000107 MGI:5009766 NCBI chr 9:37,611,173...37,634,869
Ensembl chr 9:38,552,659...38,558,078
JBrowse link
G HMCES 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (MGI:6393148|PMID:31806351) UniProt PMID:31806351 MGI:6393148 NCBI chr 3:126,339,758...126,367,166
Ensembl chr 3:133,694,676...133,721,519
JBrowse link
G KMT5B lysine methyltransferase 5B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:63,239,796...63,297,113
Ensembl chr11:66,549,230...66,581,475
JBrowse link
G KMT5C lysine methyltransferase 5C involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,381,963...52,390,507
Ensembl chr19:61,073,396...61,078,717
JBrowse link
G LOC100970806 exosome complex component MTR3 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) MGI PMID:21255825 MGI:5009766 NCBI chr 7:140,163,275...140,176,732 JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,436,532...10,454,023
Ensembl chr 1:11,654,963...11,661,526
JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:146,546,658...146,605,912
Ensembl chr 7:158,276,798...158,330,911
JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:38,721,658...38,818,488
Ensembl chr2B:155,985,960...156,052,926
JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:5,753,262...5,858,728
Ensembl chr20:5,537,488...5,642,107
JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr10:83,639,020...83,643,420 JBrowse link
G SHLD3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 5:48,376,338...48,382,052 JBrowse link
G TFRC transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998
JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:22,364,696...22,472,499
Ensembl chr15:40,519,012...40,626,741
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100976787 mismatch repair endonuclease PMS2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 7:7,433,031...7,459,560
Ensembl chr 7:6,167,403...6,202,984
JBrowse link
G MLH1 mutL homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MSH2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5462481|PMID:23241889) MGI
Ensembl
PMID:23241889 GO_REF:0000107 MGI:5462481 NCBI chr 4:2,009,276...2,119,182
Ensembl chr 4:1,945,307...2,027,425
JBrowse link
G TGFB1 transforming growth factor beta 1 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TNFSF13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3037416|PMID:14988498)
(PMID:14988498)
MGI
Ensembl
PMID:14988498 GO_REF:0000107 MGI:3037416 NCBI chr17:7,589,931...7,593,527
Ensembl chr17:7,576,465...7,579,834
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCF1 cardiotrophin like cytokine factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,722,611...62,734,279 JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:3037416|PMID:14988498) MGI PMID:14988498 MGI:3037416 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5763555|PMID:25404367) MGI
Ensembl
PMID:25404367 GO_REF:0000107 MGI:5763555 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242
JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:62368|PMID:7688139) MGI
Ensembl
PMID:7688139 GO_REF:0000107 MGI:62368 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213
JBrowse link
G CD40 CD40 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2670820|PMID:12882831) MGI
Ensembl
PMID:12882831 GO_REF:0000107 MGI:2670820 NCBI chr20:42,455,711...42,467,139
Ensembl chr20:43,541,619...43,552,994
JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) MGI PMID:12882831 MGI:2670820 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IL2 interleukin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:87443|PMID:1830926) MGI
Ensembl
PMID:1830926 GO_REF:0000107 MGI:87443 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831), (MGI:3037416|PMID:14988498) MGI PMID:12882831 PMID:14988498 MGI:2670820 MGI:3037416 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G LOC100976787 mismatch repair endonuclease PMS2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 7:7,433,031...7,459,560
Ensembl chr 7:6,167,403...6,202,984
JBrowse link
G MLH1 mutL homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MSH2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 Ensembl chr16:30,186,326...30,190,654 JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:146,546,658...146,605,912
Ensembl chr 7:158,276,798...158,330,911
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:85031|PMID:9015183) MGI
Ensembl
PMID:9015183 GO_REF:0000107 MGI:85031 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G TBX21 T-box transcription factor 21 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2670820|PMID:12882831) MGI
Ensembl
PMID:12882831 GO_REF:0000107 MGI:2670820 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617
JBrowse link
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) BHF-UCL PMID:18713990 MGI:3806904 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1G1 adaptor related protein complex 1 subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:53,201,859...53,282,437
Ensembl chr16:71,568,863...71,648,744
JBrowse link
G CD160 CD160 molecule involved_in ISO (PMID:19109136) UniProt PMID:19109136 NCBI chr 1:122,025,605...122,031,980
Ensembl chr 1:113,636,195...113,646,491
JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:94,442,507...94,464,061
Ensembl chr13:113,507,401...113,530,457
JBrowse link
G LOC100978457 patr class I histocompatibility antigen, CH28 alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:29,523,929...29,529,385
Ensembl chr 6:30,181,133...30,186,082
JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 acts_upstream_of
involved_in
ISO
IEA
(PMID:22962438) ARUK-UCL
Ensembl
PMID:22962438 GO_REF:0000107 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL2 interleukin 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:22962438) ARUK-UCL
Ensembl
PMID:22962438 GO_REF:0000107 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,400,503...2,421,132
Ensembl chr11:2,437,991...2,449,308
JBrowse link
G LGALS9 galectin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959
JBrowse link
G MHC-DMB HLA class II histocompatibility antigen, DM beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,504,074...32,510,669
Ensembl chr 6:33,619,870...33,625,685
JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:3576832 NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2176424|PMID:11894097) MGI
Ensembl
PMID:11894097 GO_REF:0000107 MGI:2176424 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) UniProt PMID:12242343 MGI:3687909 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041
JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574
JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr19:32,805,772...32,817,778
Ensembl chr19:41,553,727...41,568,555
JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:98,914,957...98,948,467
Ensembl chr 3:105,616,645...105,628,300
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216
JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617
JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216
JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855
JBrowse link
G RARA retinoic acid receptor alpha involved_in ISO (PMID:18416830) BHF-UCL PMID:18416830 NCBI chr17:16,932,485...16,980,958 JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) BHF-UCL PMID:18354165 MGI:4943387 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYB MYB proto-oncogene, transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:132,952,728...132,990,560
Ensembl chr 6:137,048,812...137,086,194
JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5617929|PMID:24645804) MGI
Ensembl
PMID:24645804 GO_REF:0000107 MGI:5617929 NCBI chr 9:37,768,566...37,921,897 JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLF aprataxin and PNKP like factor acts_upstream_of_or_within ISO (MGI:4887518|PMID:21211721) MGI PMID:21211721 MGI:4887518 NCBI chr2A:68,509,314...68,629,192
Ensembl chr2A:69,632,459...69,744,611
JBrowse link
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,073,288...28,113,041
Ensembl chr17:28,578,199...28,617,292
JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695768|PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 MGI:3695768 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G IL27RA interleukin 27 receptor subunit alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1926579|PMID:11057672) MGI
Ensembl
PMID:11057672 GO_REF:0000107 MGI:1926579 Ensembl chr19:14,323,618...14,343,627 JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3694584|PMID:17137798) MGI
Ensembl
PMID:17137798 GO_REF:0000107 MGI:3694584 NCBI chr 5:137,467,161...137,511,569
Ensembl chr 5:143,600,789...143,622,913
JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:126,418,071...126,448,917 JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3051162|PMID:15240675) MGI
Ensembl
PMID:15240675 GO_REF:0000107 MGI:3051162 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF683 zinc finger protein 683 involved_in ISO (MGI:5437828|PMID:22885984) UniProt PMID:22885984 MGI:5437828 NCBI chr 1:25,622,548...25,636,106
Ensembl chr 1:26,690,359...26,703,755
JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27 interleukin 27 involved_in ISO (PMID:12734330) UniProt PMID:12734330
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr2B:115,052,768...115,056,479
Ensembl chr2B:233,862,505...233,866,225
JBrowse link
G CCR6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr 6:165,094,563...165,109,774
Ensembl chr 6:170,069,689...170,084,779
JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3817343|PMID:18776904) MGI PMID:18776904 MGI:3817343 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729
JBrowse link
T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1C CD1c molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:133,647,482...133,651,575
Ensembl chr 1:137,437,235...137,441,075
JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (MGI:5544501|PMID:24310610) UniProt PMID:24310610 MGI:5544501 NCBI chr15:18,871,867...18,973,380
Ensembl chr15:37,120,044...37,229,211
JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265
JBrowse link
G LCP1 lymphocyte cytosolic protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:26,820,846...26,906,916 JBrowse link
G MDK midkine involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254
JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3760494|PMID:17698590) MGI
Ensembl
PMID:17698590 GO_REF:0000107 MGI:3760494 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:3760494 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295
JBrowse link
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3714085|PMID:17403904) MGI
Ensembl
PMID:17403904 GO_REF:0000107 MGI:3714085 NCBI chr10:26,613,897...26,740,670
Ensembl chr10:27,030,218...27,104,483
JBrowse link
G FGL2 fibrinogen like 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6188369|PMID:29341118) MGI
Ensembl
PMID:29341118 GO_REF:0000107 MGI:6188369 NCBI chr 7:69,114,082...69,120,575
Ensembl chr 7:82,926,266...82,932,550
JBrowse link
G ICAM1 intercellular adhesion molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G ITGAL integrin subunit alpha L involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,445,966...24,496,037
Ensembl chr16:30,843,747...30,892,597
JBrowse link
T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC4D C-type lectin domain family 4 member D acts_upstream_of_or_within ISO (MGI:5525050|PMID:23602766) MGI PMID:23602766 MGI:5525050 NCBI chr12:8,599,654...8,608,494
Ensembl chr12:8,814,680...8,823,484
JBrowse link
G CLEC4E C-type lectin domain family 4 member E acts_upstream_of_or_within ISO (MGI:5525050|PMID:23602766) MGI PMID:23602766 MGI:5525050 NCBI chr12:8,620,618...8,627,610 JBrowse link
G FCER1G Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (MGI:5525050|PMID:23602766) MGI PMID:23602766 MGI:5525050 NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810
JBrowse link
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:131,489,446...131,519,864
Ensembl chr 1:135,321,288...135,350,724
JBrowse link
T cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule ISO RGD PMID:20500684 RGD:4892204 NCBI chr 3:119,151,884...119,217,641
Ensembl chr 3:126,059,008...126,124,339
JBrowse link
G RPS6 ribosomal protein S6 acts_upstream_of_or_within ISO (MGI:3610868|PMID:16357222) MGI PMID:16357222 MGI:3610868 NCBI chr 9:19,185,455...19,189,504
Ensembl chr 9:19,674,380...19,677,722
JBrowse link
G SLC11A1 solute carrier family 11 member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:86848|PMID:9176118) MGI
Ensembl
PMID:9176118 GO_REF:0000107 MGI:86848 NCBI chr2B:105,640,613...105,655,524
Ensembl chr2B:224,238,284...224,252,941
JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:148,528,535...148,662,839
Ensembl chr 1:152,251,683...152,262,668
JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3610868|PMID:16357222) MGI
Ensembl
PMID:16357222 GO_REF:0000107 MGI:3610868 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 involved_in ISO (MGI:5607369|PMID:24859450) UniProt PMID:24859450 MGI:5607369 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G GPR183 G protein-coupled receptor 183 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:80,461,908...80,475,046
Ensembl chr13:99,601,220...99,602,305
JBrowse link
G IL21 interleukin 21 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5486592|PMID:23583643) MGI
Ensembl
PMID:23583643 GO_REF:0000107 MGI:5486592 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5486592|PMID:23583643) MGI
Ensembl
PMID:23583643 GO_REF:0000107 MGI:5486592 NCBI chr 9:93,975,164...94,031,516
Ensembl chr 9:122,313,791...122,365,102
JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRACR2A calcium release activated channel regulator 2A involved_in ISO (PMID:29987160)
(MGI:6195365|PMID:29987160)
UniProt PMID:29987160 MGI:6195365 NCBI chr12:3,729,241...3,875,715
Ensembl chr12:3,655,031...3,737,592
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G HMGB1 high mobility group box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G IL18R1 interleukin 18 receptor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2136797|PMID:10227969) MGI
Ensembl
PMID:10227969 GO_REF:0000107 MGI:2136797 NCBI chr2A:99,419,686...99,462,650 JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3621346|PMID:16081776) MGI
Ensembl
PMID:16081776 GO_REF:0000107 MGI:3621346 NCBI chr19:41,948,559...41,987,121
Ensembl chr19:50,554,864...50,590,223
JBrowse link
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:131,489,446...131,519,864
Ensembl chr 1:135,321,288...135,350,724
JBrowse link
G TMEM98 transmembrane protein 98 involved_in ISO (MGI:6294180|PMID:25946230) UniProt PMID:25946230 MGI:6294180 NCBI chr17:23,844,747...23,858,390
Ensembl chr17:24,133,357...24,146,912
JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:4838368|PMID:20706986) MGI PMID:20706986 MGI:4838368 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G SPN sialophorin involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,035,243...30,036,445 JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,075,768...56,100,749
Ensembl chr14:74,919,115...74,943,652
JBrowse link
G ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,276,454...96,323,287
Ensembl chr10:99,768,566...99,813,568
JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,461,553...40,200,118
Ensembl chr15:57,771,735...57,980,460
JBrowse link
G RORC RAR related orphan receptor C acts_upstream_of_or_within
involved_in
ISO (MGI:3817792|PMID:18792410)
(MGI:3692468|PMID:16990136), (MGI:3772713|PMID:18164222)
MGI
GO_Central
PMID:16990136 PMID:18164222 PMID:18792410 MGI:3692468 MGI:3772713 MGI:3817792 NCBI chr 1:127,164,725...127,190,479
Ensembl chr 1:130,808,705...130,834,490
JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,075,768...56,100,749
Ensembl chr14:74,919,115...74,943,652
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:3692468|PMID:16990136)
(MGI:6142555|PMID:27893700)
UniProt PMID:16990136 PMID:27893700 MGI:3692468 MGI:6142555 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089
JBrowse link
G IRF4 interferon regulatory factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:206,282...226,487
Ensembl chr 6:342,718...356,654
JBrowse link
G LY9 lymphocyte antigen 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:136,151,608...136,185,365
Ensembl chr 1:140,075,646...140,107,784
JBrowse link
G OTUD5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO (MGI:5621075|PMID:25470037) MGI PMID:25470037 MGI:5621075 NCBI chr  X:41,219,536...41,256,219 JBrowse link
G SLAMF6 SLAM family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:135,838,862...135,878,207
Ensembl chr 1:139,761,121...139,799,348
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,075,768...56,100,749
Ensembl chr14:74,919,115...74,943,652
JBrowse link
G BCL3 BCL3 transcription coactivator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3621346|PMID:16081776) MGI
Ensembl
PMID:16081776 GO_REF:0000107 MGI:3621346 NCBI chr19:41,696,162...41,708,485
Ensembl chr19:50,304,171...50,313,005
JBrowse link
G BCL6 BCL6 transcription repressor acts_upstream_of
involved_in
ISO
IEA
(MGI:2450484|PMID:12594267) MGI
Ensembl
PMID:12594267 GO_REF:0000107 MGI:2450484 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:4838368|PMID:20706986) MGI PMID:20706986 MGI:4838368 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:4838368|PMID:20706986) MGI PMID:20706986 MGI:4838368 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL6 interleukin 6 acts_upstream_of ISO (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chr 7:23,415,922...23,420,767 JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (MGI:61362|PMID:8434133) MGI PMID:8434133 MGI:61362 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756
JBrowse link
G IL12B interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:154,706,467...154,722,231
Ensembl chr 5:161,325,303...161,335,381
JBrowse link
G PTGER4 prostaglandin E receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148
JBrowse link
G RORC RAR related orphan receptor C involved_in ISO (MGI:2686818|PMID:14691482) UniProt PMID:14691482 MGI:2686818 NCBI chr 1:127,164,725...127,190,479
Ensembl chr 1:130,808,705...130,834,490
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15338
    immune system process 2280
      leukocyte activation 911
        lymphocyte activation 739
          lymphocyte activation involved in immune response 189
            B cell activation involved in immune response + 91
            T cell activation involved in immune response + 95
            natural killer cell activation involved in immune response + 20
Path 2
Term Annotations click to browse term
  biological_process 15338
    cellular process 14183
      cell activation 1056
        cell activation involved in immune response 280
          leukocyte activation involved in immune response 276
            lymphocyte activation involved in immune response 189
              B cell activation involved in immune response + 91
              T cell activation involved in immune response + 95
              natural killer cell activation involved in immune response + 20
paths to the root