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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of immune response
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Accession:GO:0002253 term browser browse the term
Definition:Any process that initiates an immune response.


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activation of immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:3528786|PMID:15692051) MGI PMID:15692051 MGI:3528786 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (MGI:3818783|PMID:18045533) MGI PMID:18045533 MGI:3818783 NCBI chrNW_004936529:264,535...266,451 JBrowse link
activation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO (PMID:19158675), (PMID:19158676), (PMID:19158679)
(MGI:3839523|PMID:19158676)
UniProt PMID:19158675 PMID:19158676 PMID:19158679 MGI:3839523 NCBI chrNW_004936740:1,447,869...1,460,836 JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:30007416)
(MGI:5487472|PMID:23258413)
(MGI:5505711|PMID:23929945), (MGI:5908326|PMID:24077100)
(PMID:23258413)
UniProt PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More... MGI:5487472 MGI:5505711 MGI:5908326 NCBI chrNW_004936859:797,469...807,036 JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936541:1,458,474...1,463,039 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:24971542) UniProt PMID:24971542 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:20628368) UniProt PMID:20628368 NCBI chrNW_004936835:316,767...321,999 JBrowse link
G LOC110596870 RNA-binding protein 14 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936599:2,968,178...2,984,033 JBrowse link
G Matr3 matrin 3 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936531:8,385,919...8,418,753 JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:20628368)
(PMID:18818105)
UniProt
BHF-UCL
PMID:18818105 PMID:20628368 NCBI chrNW_004936485:14,842,778...14,859,163 JBrowse link
G Nlrc4 NLR family CARD domain containing 4 involved_in ISO (MGI:3662990|PMID:16648852) UniProt PMID:16648852 MGI:3662990 NCBI chrNW_004936493:1,189,940...1,233,408 JBrowse link
G Nono non-POU domain containing octamer binding involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936762:322,413...343,126 JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISO (PMID:26046437) UniProt PMID:26046437 NCBI chrNW_004936721:825,171...830,010 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936590:4,722,914...4,887,615 JBrowse link
G Pspc1 paraspeckle component 1 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936720:1,876,726...1,941,705 JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:21575908)
(MGI:3839029|PMID:19158675)
UniProt PMID:19158675 PMID:21575908 MGI:3839029 NCBI chrNW_004936501:13,550,702...13,552,774 JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936474:17,776,490...17,791,966 JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (PMID:22783022) BHF-UCL PMID:22783022 NCBI chrNW_004936471:34,206,084...34,260,538 JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:18818105)
(MGI:5487473|PMID:23258412), (MGI:5487515|PMID:21947006)
BHF-UCL
UniProt
PMID:18818105 PMID:21947006 PMID:23258412 MGI:5487473 MGI:5487515 NCBI chrNW_004936531:8,555,966...8,562,829 JBrowse link
G Tbk1 TANK binding kinase 1 acts_upstream_of_or_within ISO (MGI:3530402|PMID:15661922) MGI PMID:15661922 MGI:3530402 NCBI chrNW_004936545:2,763,755...2,809,229 JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (MGI:3530402|PMID:15661922) MGI PMID:15661922 MGI:3530402 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 involved_in ISO (PMID:20628368) UniProt PMID:20628368 NCBI chrNW_004936630:2,906,573...2,938,837 JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936586:1,055,478...1,137,924 JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chrNW_004936492:303,843...325,812 JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISO (MGI:6434626|PMID:32296175), (MGI:6436412|PMID:32200799) UniProt PMID:32200799 PMID:32296175 MGI:6434626 MGI:6436412 NCBI chrNW_004936530:398,980...408,798 JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO (PMID:30135424), (PMID:30193849)
(MGI:6209107|PMID:30135424), (MGI:6271678|PMID:30193849)
UniProt PMID:30135424 PMID:30193849 MGI:6209107 MGI:6271678 NCBI chrNW_004936670:3,048,914...3,049,809 JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:10587647) UniProt PMID:10587647 NCBI chrNW_004936475:23,994,130...24,032,829 JBrowse link
G Cd19 CD19 molecule involved_in ISO (PMID:1373518) UniProt PMID:1373518 NCBI chrNW_004936501:11,793,903...11,807,410 JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 acts_upstream_of_or_within ISO (MGI:3578441|PMID:15843560) MGI PMID:15843560 MGI:3578441 NCBI chrNW_004936567:924,526...930,267 JBrowse link
G Sh2b2 SH2B adaptor protein 2 acts_upstream_of_or_within ISO (MGI:1859033|PMID:10872802) MGI PMID:10872802 MGI:1859033 NCBI chrNW_004936543:1,799,610...1,820,889 JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:1927957|PMID:11120811), (MGI:3839222|PMID:19228876) MGI PMID:11120811 PMID:19228876 MGI:1927957 MGI:3839222 NCBI chrNW_004936487:17,690,206...17,819,619 JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:9020138) UniProt PMID:9020138 NCBI chrNW_004936475:23,994,130...24,032,829 JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:876631)
(PMID:23555801)
UniProt
ARUK-UCL
PMID:876631 PMID:23555801 NCBI chrNW_004936675:3,228,982...3,246,617 JBrowse link
G Blnk B cell linker involved_in ISO (PMID:9697839)
(PMID:11606584)
UniProt
ARUK-UCL
PMID:9697839 PMID:11606584 NCBI chrNW_004936636:3,220,554...3,290,054 JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO (PMID:15509800) ARUK-UCL PMID:15509800 NCBI chrNW_004936813:429,400...467,481 JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within
ISO (MGI:5476553|PMID:23499492)
(MGI:1095647|PMID:9254656)
UniProt
MGI
PMID:9254656 PMID:23499492 MGI:1095647 MGI:5476553 NCBI chrNW_004936501:11,793,903...11,807,410 JBrowse link
G Cd38 CD38 molecule involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004936477:12,109,761...12,156,037 JBrowse link
G Cd79a CD79a molecule acts_upstream_of_or_within ISO (MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447) MGI PMID:1373499 PMID:8626447 MGI:3521842 MGI:79455 NCBI chrNW_004936706:561,195...564,577 JBrowse link
G Cd79b CD79b molecule acts_upstream_of_or_within ISO (MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447) MGI PMID:1373499 PMID:8626447 MGI:3521842 MGI:79455 NCBI chrNW_004936541:4,534,233...4,537,448 JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004936631:484,356...489,643 JBrowse link
G Klhl6 kelch like family member 6 involved_in ISO (MGI:3603885|PMID:16166635) UniProt PMID:16166635 MGI:3603885 NCBI chrNW_004936578:6,226,533...6,284,343 JBrowse link
G Lat2 linker for activation of T cells family member 2 involved_in ISO (PMID:12514734) HGNC-UCL PMID:12514734 NCBI chrNW_004936543:3,250,956...3,262,668 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:77358|PMID:7499277) MGI PMID:7499277 MGI:77358 NCBI chrNW_004936474:15,293,115...15,314,072 JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within ISO (MGI:3769059|PMID:16249387) MGI PMID:16249387 MGI:3769059 NCBI chrNW_004936514:10,980,136...10,983,323 JBrowse link
G LOC101976824 nuclear factor of activated T cells 2 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004936514:3,453,475...3,579,292 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253)
(MGI:77358|PMID:7499277)
MGI PMID:7499277 PMID:23509253 MGI:5471851 MGI:77358 NCBI chrNW_004936496:2,578,598...2,698,165 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:1095647|PMID:9254656) MGI PMID:9254656 MGI:1095647 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:3829850|PMID:18955699) UniProt PMID:18955699 MGI:3829850 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Ms4a1 membrane spanning 4-domains A1 involved_in ISO (PMID:18474602) UniProt PMID:18474602 NCBI chrNW_004936581:2,466,294...2,477,530 JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004936512:11,683,330...11,734,423 JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 acts_upstream_of_or_within ISO (MGI:3044463|PMID:15143214) MGI PMID:15143214 MGI:3044463 NCBI chrNW_004936718:367,996...399,030 JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (MGI:1861532|PMID:10925250)
(PMID:11606584)
(PMID:15509800)
UniProt
ARUK-UCL
PMID:10925250 PMID:11606584 PMID:15509800 MGI:1861532 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
G Plekha1 pleckstrin homology domain containing A1 involved_in ISO (PMID:12101241) UniProt PMID:12101241 NCBI chrNW_004936486:11,203,873...11,241,028 JBrowse link
G Prkcb protein kinase C beta involved_in ISO (MGI:3626015|PMID:12118249) UniProt PMID:12118249 MGI:3626015 NCBI chrNW_004936501:8,410,273...8,729,238 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253)
(MGI:1095647|PMID:9254656)
MGI PMID:9254656 PMID:23509253 MGI:1095647 MGI:5471851 NCBI chrNW_004936709:864,206...884,630 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in
ISO (MGI:1095647|PMID:9254656)
(MGI:77358|PMID:7499277)
(MGI:3687418|PMID:8692271)
MGI
UniProt
PMID:7499277 PMID:8692271 PMID:9254656 MGI:1095647 MGI:3687418 MGI:77358 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Rftn1 raftlin, lipid raft linker 1 involved_in ISO (PMID:12805216) UniProt PMID:12805216 NCBI chrNW_004936473:9,119,234...9,317,696 JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in ISO (PMID:9233773) UniProt PMID:9233773 NCBI chrNW_004936543:1,799,610...1,820,889 JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in
ISO (MGI:77358|PMID:7499277), (MGI:79455|PMID:8626447)
(PMID:15509800)
MGI
ARUK-UCL
PMID:7499277 PMID:8626447 PMID:15509800 MGI:77358 MGI:79455 NCBI chrNW_004936780:1,553,605...1,601,036 JBrowse link
G Tec tec protein tyrosine kinase involved_in ISO (PMID:10518561) UniProt PMID:10518561 NCBI chrNW_004936482:14,248,277...14,341,329 JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004936731:417,610...767,427 JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) MGI PMID:12719478 MGI:3042099 NCBI chrNW_004936902:436,224...446,435 JBrowse link
G LOC101971238 free fatty acid receptor 2 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chrNW_004936570:895,364...896,356 JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) MGI PMID:12719478 MGI:3042099 NCBI chrNW_004936576:522,234...531,660 JBrowse link
complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2 complement C2 involved_in ISO (PMID:19302245) BHF-UCL PMID:19302245 NCBI chrNW_004936727:1,602,400...1,615,974 JBrowse link
G C3 complement C3 acts_upstream_of_or_within
involved_in
ISO (MGI:3833206|PMID:18947875)
(MGI:5617896|PMID:25284781)
(PMID:19302245)
RGD
MGI
BHF-UCL
PMID:18947875 PMID:19302245 PMID:20712003 PMID:25284781 MGI:3833206 MGI:5617896 RGD:5129529 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G C8a complement C8 alpha chain acts_upstream_of_or_within ISO (PMID:12413696) MGI PMID:12413696 NCBI chrNW_004936522:4,686,306...4,745,175 JBrowse link
G Cfb complement factor B ISO RGD PMID:6906329 RGD:2311339 NCBI chrNW_004936727:1,595,872...1,602,274 JBrowse link
G Cfi complement factor I involved_in ISO (MGI:3773599|PMID:18202746) MGI PMID:18202746 MGI:3773599 NCBI chrNW_004936563:960,883...998,136 JBrowse link
G Colec11 collectin subfamily member 11 involved_in ISO (PMID:23954398) UniProt PMID:23954398 NCBI chrNW_004936532:1,757,288...1,776,053 JBrowse link
G Fcn3 ficolin 3 involved_in ISO (PMID:22851708) UniProt PMID:22851708 NCBI chrNW_004936474:11,680,166...11,685,214 JBrowse link
G LOC101975827 complement C4-A involved_in
acts_upstream_of_or_within
ISO (PMID:19302245)
(MGI:51812|PMID:1438267), (MGI:66045|PMID:8133084)
BHF-UCL
MGI
PMID:1438267 PMID:8133084 PMID:19302245 MGI:51812 MGI:66045 NCBI chrNW_004936727:1,556,204...1,570,084 JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19162005) BHF-UCL PMID:19162005 NCBI chrNW_004936667:232,807...245,131 JBrowse link
complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfb complement factor B acts_upstream_of_or_within ISO (MGI:1096110|PMID:9238044)
(MGI:6100611|PMID:27564415)
MGI PMID:9238044 PMID:27564415 MGI:1096110 MGI:6100611 NCBI chrNW_004936727:1,595,872...1,602,274 JBrowse link
G Cfd complement factor D acts_upstream_of_or_within ISO (MGI:6100611|PMID:27564415) MGI PMID:27564415 MGI:6100611 NCBI chrNW_004936588:350,925...352,732 JBrowse link
G Cr2 complement C3d receptor 2 acts_upstream_of_or_within_negative_effect
involved_in
ISO (MGI:4421084|PMID:19828624)
(PMID:11981823)
MGI
ARUK-UCL
PMID:11981823 PMID:19828624 MGI:4421084 NCBI chrNW_004936557:5,246,770...5,256,608 JBrowse link
G LOC101961626 complement factor properdin involved_in ISO (MGI:3773929|PMID:18292556) MGI PMID:18292556 MGI:3773929 NCBI chrNW_004936502:13,391,613...13,398,723 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain acts_upstream_of_or_within ISO (MGI:2177393|PMID:11901193) MGI PMID:11901193 MGI:2177393 NCBI chrNW_004936474:8,007,953...8,010,591 JBrowse link
G LOC101969640 C-reactive protein ISO RGD PMID:16367929 RGD:1580273 NCBI chrNW_004936740:885,855...888,854 JBrowse link
complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Colec11 collectin subfamily member 11 involved_in ISO (PMID:25912189) UniProt PMID:25912189 NCBI chrNW_004936532:1,757,288...1,776,053 JBrowse link
G Fcn3 ficolin 3 involved_in
acts_upstream_of_or_within
ISO (PMID:11907111)
(MGI:5473786|PMID:16328467)
UniProt
MGI
PMID:11907111 PMID:16328467 MGI:5473786 NCBI chrNW_004936474:11,680,166...11,685,214 JBrowse link
G Krt1 keratin 1 involved_in ISO (PMID:11549596) UniProt PMID:11549596 NCBI chrNW_004936512:10,084,764...10,090,312 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:17182967)
(MGI:3789229|PMID:18424734)
UniProt PMID:17182967 PMID:18424734 MGI:3789229 NCBI chrNW_004936578:2,804,460...2,857,731 JBrowse link
G Masp2 MBL associated serine protease 2 involved_in
acts_upstream_of_or_within
ISO (PMID:17182967), (PMID:9087411)
(MGI:5473786|PMID:16328467)
UniProt
MGI
PMID:9087411 PMID:16328467 PMID:17182967 MGI:5473786 NCBI chrNW_004936474:100,584...113,781 JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5ar1 complement C5a receptor 1 involved_in ISO (PMID:10571060) UniProt PMID:10571060 NCBI chrNW_004936664:1,026,216...1,033,438 JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 involved_in ISO (PMID:10571060) UniProt PMID:10571060 NCBI chrNW_004936892:347,547...355,143 JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:15907827), (PMID:19135435) UniProt PMID:15907827 PMID:19135435 NCBI chrNW_004936671:780,173...827,628 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:16360013), (PMID:22962438) ARUK-UCL PMID:16360013 PMID:22962438 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chrNW_004936903:514,278...517,975 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:3703139|PMID:16272347) UniProt PMID:16272347 MGI:3703139 NCBI chrNW_004936496:2,578,598...2,698,165 JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:2142460) ARUK-UCL PMID:2142460 NCBI chrNW_004937131:80,014...96,114 JBrowse link
G Myo1g myosin IG involved_in ISO (MGI:5586792|PMID:23038771) UniProt PMID:23038771 MGI:5586792 NCBI chrNW_004936478:19,788,032...19,802,546 JBrowse link
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chrNW_004936727:1,866,235...1,885,266 JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chrNW_004936727:1,921,452...1,924,395 JBrowse link
immune response-activating signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zc3h12a zinc finger CCCH-type containing 12A involved_in ISO (PMID:19909337) UniProt PMID:19909337 NCBI chrNW_004936474:19,714,145...19,722,512 JBrowse link
innate immune response-activating signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050) RGD
MGI
PMID:10946279 PMID:11471050 PMID:15843577 MGI:1888643 MGI:2148385 RGD:1600482 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G LOC101964865 complement receptor type 1 acts_upstream_of ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO (PMID:24169826)
(PMID:26017478)
ARUK-UCL PMID:24169826 PMID:26017478 NCBI chrNW_004936570:960,592...971,688 JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chrNW_004937131:80,014...96,114 JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) UniProt PMID:28039360 MGI:5896692 NCBI chrNW_004936595:608,730...611,871 JBrowse link
G Lpxn leupaxin involved_in ISO (PMID:17640867)
(MGI:3722965|PMID:17640867)
UniProt PMID:17640867 MGI:3722965 NCBI chrNW_004936581:3,750,819...3,784,488 JBrowse link
G Plcl2 phospholipase C like 2 acts_upstream_of_or_within ISO (MGI:2677607|PMID:14517301) MGI PMID:14517301 MGI:2677607 NCBI chrNW_004936473:9,628,612...9,801,713 JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:6211481)
(PMID:28657829)
RGD
UniProt
PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (MGI:1888643|PMID:10946279) MGI PMID:10946279 MGI:1888643 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) UniProt PMID:11485744 NCBI chrNW_004936578:2,804,460...2,857,731 JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:10531307) UniProt PMID:10531307 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chrNW_004936526:488,604...615,265 JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in ISO (PMID:17051150) UniProt PMID:17051150 NCBI chrNW_004936635:2,167,633...2,191,725 JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpb complement component 4 binding protein beta involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chrNW_004936557:5,546,692...5,561,531 JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:10531307), (PMID:6910481) UniProt PMID:6910481 PMID:10531307 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chrNW_004936526:488,604...615,265 JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101959212 alpha-2-macroglobulin involved_in ISO (PMID:12538697) UniProt PMID:12538697 NCBI chrNW_004936870:424,832...468,303 JBrowse link
G Serping1 serpin family G member 1 involved_in ISO (PMID:10946292) UniProt PMID:10946292 NCBI chrNW_004936581:4,911,403...4,924,484 JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chrNW_004936473:7,580,495...7,647,471 JBrowse link
G LOC101967799 leukocyte surface antigen CD47 involved_in ISO PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chrNW_004936645:1,363,406...1,408,624 JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btnl2 butyrophilin like 2 acts_upstream_of_or_within ISO (MGI:3775536|PMID:16751379) MGI PMID:16751379 MGI:3775536 NCBI chrNW_004936727:567,656...587,784 JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (MGI:3041371|PMID:14738763) MGI PMID:14738763 MGI:3041371 NCBI chrNW_004936701:1,157,790...1,353,375 JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chrNW_004936867:478,625...485,905 JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (MGI:2672999|PMID:12883552) UniProt PMID:12883552 MGI:2672999 NCBI chrNW_004936562:2,690,907...2,733,455 JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:5583944|PMID:24714587) MGI PMID:24714587 MGI:5583944 NCBI chrNW_004936633:1,459,487...1,528,080 JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO (PMID:12447358) UniProt PMID:12447358 NCBI chrNW_004936541:325,443...338,426 JBrowse link
G Elf1 E74 like ETS transcription factor 1 acts_upstream_of_or_within ISO (MGI:3041371|PMID:14738763) MGI PMID:14738763 MGI:3041371 NCBI chrNW_004936667:449,682...553,780 JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004936489:10,413,374...10,457,771 JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) ARUK-UCL PMID:18619870 MGI:3803048 NCBI chrNW_004936474:14,102,080...14,119,592 JBrowse link
G Lgals3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chrNW_004936697:20,861...38,568 JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G LOC101959784 prion protein involved_in ISO (MGI:4943618|PMID:20145049) BHF-UCL PMID:20145049 MGI:4943618 NCBI chrNW_004936485:14,104,829...14,118,614 JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO (MGI:2675524|PMID:12970181) MGI PMID:12970181 MGI:2675524 NCBI chrNW_004936698:650,225...746,593 JBrowse link
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chrNW_004936669:1,065,901...1,067,214 JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:5320871|PMID:22080863) UniProt PMID:22080863 MGI:5320871 NCBI chrNW_004936626:2,390,004...2,472,039 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chrNW_004936690:2,180,804...2,232,869 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:82729|PMID:9064344) MGI PMID:9064344 MGI:82729 NCBI chrNW_004936709:864,206...884,630 JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (PMID:12913111)
(MGI:4942249|PMID:12913111)
(PMID:11259588), (PMID:9780142)
UniProt PMID:9780142 PMID:11259588 PMID:12913111 MGI:4942249 NCBI chrNW_004936562:1,161,764...1,234,800 JBrowse link
G Pvrig PVR related immunoglobulin domain containing involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chrNW_004936543:465,781...467,150 JBrowse link
G Sh2d1a SH2 domain containing 1A involved_in ISO (PMID:9774102) UniProt PMID:9774102 NCBI chrNW_004936479:6,258,953...6,281,552 JBrowse link
G Sla2 Src like adaptor 2 involved_in ISO (PMID:11891219) UniProt PMID:11891219 NCBI chrNW_004936561:4,408,531...4,427,476 JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISO (MGI:1096761|PMID:9285719) UniProt PMID:9285719 MGI:1096761 NCBI chrNW_004936542:4,323,905...4,329,940 JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing A acts_upstream_of_or_within ISO (MGI:3041371|PMID:14738763) MGI PMID:14738763 MGI:3041371 NCBI chrNW_004936500:1,437,658...1,474,705 JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chrNW_004936518:1,471,116...1,532,733 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3687418|PMID:8692271) UniProt PMID:8692271 MGI:3687418 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in ISO (PMID:20237408)
(MGI:5476553|PMID:23499492)
UniProt PMID:20237408 PMID:23499492 MGI:5476553 NCBI chrNW_004936794:664,089...670,294 JBrowse link
G Cmtm3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (MGI:3047050|PMID:15196959) MGI PMID:15196959 MGI:3047050 NCBI chrNW_004936475:16,929,726...16,935,403 JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chrNW_004936603:2,631,781...3,146,104 JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in ISO (MGI:3044463|PMID:15143214) HGNC-UCL PMID:15143214 MGI:3044463 NCBI chrNW_004936718:367,996...399,030 JBrowse link
G Prkcb protein kinase C beta involved_in ISO (MGI:3700457|PMID:16301747) UniProt PMID:16301747 MGI:3700457 NCBI chrNW_004936501:8,410,273...8,729,238 JBrowse link
G Prkch protein kinase C eta involved_in ISO (PMID:18780722) UniProt PMID:18780722 NCBI chrNW_004936495:5,426,243...5,638,250 JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO (MGI:5586914|PMID:25074919) MGI PMID:25074919 MGI:5586914 NCBI chrNW_004936506:3,298,259...3,425,126 JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (PMID:10518561) BHF-UCL PMID:10518561 NCBI chrNW_004936582:877,241...908,697 JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chrNW_004936518:1,471,116...1,532,733 JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:29384235) ARUK-UCL PMID:29384235 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Phb prohibitin involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chrNW_004936490:12,127,065...12,138,870 JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6275756|PMID:30548312) ARUK-UCL PMID:30548312 MGI:6275756 NCBI chrNW_004936476:18,659,725...18,665,406 JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004936496:2,578,598...2,698,165 JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chrNW_004936492:9,477,483...9,526,692 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chrNW_004936562:1,161,764...1,234,800 JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chrNW_004936690:275,840...363,752 JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chrNW_004936487:18,305,537...18,411,170 JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chrNW_004936524:8,252,321...8,290,747 JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (MGI:3640996|PMID:11435465) MGI PMID:11435465 MGI:3640996 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004936608:434,740...442,162 JBrowse link
G Card11 caspase recruitment domain family member 11 involved_in ISO (PMID:12154360)
(MGI:6695669|PMID:12154356)
UniProt PMID:12154356 PMID:12154360 MGI:6695669 NCBI chrNW_004936823:580,438...621,298 JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3847607|PMID:17785582) BHF-UCL PMID:17785582 MGI:3847607 NCBI chrNW_004936490:15,575,764...15,579,766 JBrowse link
G Cd81 CD81 molecule involved_in ISO (PMID:23858057) UniProt PMID:23858057 NCBI chrNW_004936794:664,089...670,294 JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (MGI:3656194|PMID:16501569) MGI PMID:16501569 MGI:3656194 NCBI chrNW_004936475:3,750,917...3,812,118 JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004936809:1,280,254...1,306,964 JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chrNW_004936706:940,585...952,484 JBrowse link
G LOC101972231 T-cell receptor-associated transmembrane adapter 1 acts_upstream_of_or_within ISO (PMID:11390434) MGI PMID:11390434 NCBI chrNW_004936645:2,459,524...2,491,016 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chrNW_004936706:1,470,910...1,498,986 JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (MGI:4849903|PMID:20819079) UniProt PMID:20819079 MGI:4849903 NCBI chrNW_004936664:524,532...551,451 JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) ParkinsonsUK-UCL PMID:26021297 NCBI chrNW_004936557:6,673,092...6,679,715 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chrNW_004936599:3,800,142...3,810,583 JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chrNW_004936498:4,198,189...4,204,531 JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 involved_in ISO (MGI:5432321|PMID:22561606) UniProt PMID:22561606 MGI:5432321 NCBI chrNW_004936891:512,882...549,676 JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule involved_in ISO (PMID:9382888)
(MGI:1100180|PMID:9382888)
UniProt PMID:9382888 MGI:1100180 NCBI chrNW_004936501:11,793,903...11,807,410 JBrowse link
G Gcsam germinal center associated signaling and motility involved_in ISO (PMID:23299888) UniProt PMID:23299888 NCBI chrNW_004936834:919,655...931,253 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:2152233|PMID:11672542) UniProt PMID:11672542 MGI:2152233 NCBI chrNW_004936496:2,578,598...2,698,165 JBrowse link
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G LOC101962230 complement C1q binding protein involved_in ISO (PMID:8195709) UniProt PMID:8195709 NCBI chrNW_004936677:2,371,400...2,376,608 JBrowse link
G Phb2 prohibitin 2 NOT|involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chrNW_004936709:854,493...859,182 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chrNW_004936526:488,604...615,265 JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (MGI:1330710|PMID:9892684) MGI PMID:9892684 MGI:1330710 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase ISO RGD PMID:9325302 RGD:2303720 NCBI chrNW_004936471:33,757,778...33,777,871 JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISO PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chrNW_004936519:8,759,702...8,790,823 JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (MGI:3834538|PMID:17341663)
(MGI:3050742|PMID:15235600)
MGI PMID:15235600 PMID:17341663 MGI:3050742 MGI:3834538 NCBI chrNW_004936543:7,405,070...7,447,940 JBrowse link
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2a Fc fragment of IgG receptor IIa ISO RGD PMID:16482158 PMID:22184119 RGD:11041001 RGD:2293335 NCBI chrNW_004937131:15,542...22,099 JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:3629264 NCBI chrNW_004936608:434,740...442,162 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:3042327|PMID:14752163) MGI PMID:14752163 MGI:3042327 NCBI chrNW_004936474:15,293,115...15,314,072 JBrowse link
G Malt1 MALT1 paracaspase acts_upstream_of_or_within ISO (MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:3629264 NCBI chrNW_004936497:5,854,361...5,910,719 JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:3580753|PMID:15917799) BHF-UCL PMID:15917799 MGI:3580753 NCBI chrNW_004936481:13,919,006...13,973,868 JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (MGI:5920164|PMID:28598420) MGI PMID:28598420 MGI:5920164 NCBI chrNW_004936891:512,882...549,676 JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101955362 natural killer cells antigen CD94 involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004936902:302,811...309,379 JBrowse link
G LOC101962495 transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004936570:457,993...460,735 JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (MGI:3844414|PMID:19136564), (MGI:5300086|PMID:22041900) ARUK-UCL PMID:19136564 PMID:22041900 MGI:3844414 MGI:5300086 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO (MGI:3844414|PMID:19136564) ARUK-UCL PMID:19136564 MGI:3844414 NCBI chrNW_004936780:1,553,605...1,601,036 JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101962495 transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004936570:457,993...460,735 JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:3798766|PMID:18305217) MGI PMID:18305217 MGI:3798766 NCBI chrNW_004936487:17,690,206...17,819,619 JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004936608:434,740...442,162 JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:3773982|PMID:18228248) MGI PMID:18228248 MGI:3773982 NCBI chrNW_004936592:4,728,371...4,833,830 JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within ISO (MGI:3691409|PMID:17028169) MGI PMID:17028169 MGI:3691409 NCBI chrNW_004936512:6,652,836...6,666,171 JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO (MGI:3526783|PMID:15637280), (MGI:3691409|PMID:17028169) MGI PMID:15637280 PMID:17028169 MGI:3526783 MGI:3691409 NCBI chrNW_004936469:25,494,820...25,745,783 JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (MGI:5544872|PMID:23793062) MGI PMID:23793062 MGI:5544872 NCBI chrNW_004936475:18,036,233...18,049,144 JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (MGI:2665211|PMID:12697763) MGI PMID:12697763 MGI:2665211 NCBI chrNW_004936701:1,157,790...1,353,375 JBrowse link
G Cd247 CD247 molecule acts_upstream_of_or_within ISO (MGI:3640996|PMID:11435465) MGI PMID:11435465 MGI:3640996 NCBI chrNW_004936481:18,544,129...18,605,239 JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (MGI:5544872|PMID:23793062) MGI PMID:23793062 MGI:5544872 NCBI chrNW_004936631:335,411...363,407 JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (MGI:3577956|PMID:10485657) MGI PMID:10485657 MGI:3577956 NCBI chrNW_004936542:3,379,361...3,390,677 JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (MGI:3798766|PMID:18305217) MGI PMID:18305217 MGI:3798766 NCBI chrNW_004936619:2,447,686...2,479,589 JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822)
(MGI:5751612|PMID:26774822)
UniProt PMID:26774822 MGI:5751612 NCBI chrNW_004936567:6,131,433...6,353,003 JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004936558:1,196,111...1,205,321 JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004936488:4,150,504...4,156,483 JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004936474:26,075,503...26,187,459 JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004936493:5,213,036...5,217,670 JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004936578:5,716,333...5,724,869 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (MGI:1331533|PMID:10072494), (MGI:1929588|PMID:11265635) MGI PMID:10072494 PMID:11265635 MGI:1331533 MGI:1929588 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Fyb2 FYN binding protein 2 involved_in ISO (PMID:27335501) UniProt PMID:27335501 NCBI chrNW_004936522:4,802,274...4,867,954 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:7722293) UniProt PMID:7722293 NCBI chrNW_004936679:388,500...588,518 JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (MGI:5285154|PMID:20696860) UniProt PMID:20696860 MGI:5285154 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chrNW_004936888:375,372...378,125 JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Itk IL2 inducible T cell kinase involved_in ISO (MGI:1335923|PMID:10213685) UniProt PMID:10213685 MGI:1335923 NCBI chrNW_004936515:5,891,873...5,952,400 JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISO (PMID:9045636) UniProt PMID:9045636 NCBI chrNW_004936474:15,088,815...15,131,048 JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004936609:4,522,158...4,565,505 JBrowse link
G LOC101956536 C-type lectin domain family 2 member A acts_upstream_of_or_within ISO (MGI:3622591|PMID:16143319) MGI PMID:16143319 MGI:3622591 NCBI chrNW_004936902:583,850...586,981 JBrowse link
G LOC101963197 HLA class II histocompatibility antigen, DP beta 1 chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chrNW_004936476:25,730,800...25,741,089 JBrowse link
G LOC101971458 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within ISO (MGI:893249|PMID:9208839) MGI PMID:9208839 MGI:893249 NCBI chrNW_004936744:1,000,105...1,012,712 JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833)
(MGI:6142401|PMID:25282160)
UniProt PMID:15125833 PMID:25282160 MGI:6142401 NCBI chrNW_004936497:5,854,361...5,910,719 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:82729|PMID:9064344) MGI PMID:9064344 MGI:82729 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004936570:464,513...471,333 JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004936630:1,601,006...1,633,844 JBrowse link
G Nras NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chrNW_004936627:73,413...82,590 JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chrNW_004936591:5,152,491...5,666,728 JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chrNW_004936480:8,123,437...9,235,586 JBrowse link
G Plcg1 phospholipase C gamma 1 acts_upstream_of_or_within ISO (MGI:3531056|PMID:15728238) MGI PMID:15728238 MGI:3531056 NCBI chrNW_004936561:598,372...631,575 JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (MGI:3531056|PMID:15728238) MGI PMID:15728238 MGI:3531056 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (PMID:17077180) BHF-UCL PMID:17077180 NCBI chrNW_004936664:524,532...551,451 JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:3760494 NCBI chrNW_004936488:2,464,623...2,528,807 JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:3760494 NCBI chrNW_004936526:3,584,194...3,611,719 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 acts_upstream_of_or_within ISO (MGI:3042327|PMID:14752163) MGI PMID:14752163 MGI:3042327 NCBI chrNW_004936690:2,180,804...2,232,869 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (PMID:10358156)
(MGI:6201809|PMID:12496963)
UniProt
ARUK-UCL
PMID:10358156 PMID:12496963 MGI:6201809 RGD:1358565 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chrNW_004936485:18,057,569...18,071,787 JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004936481:13,919,006...13,973,868 JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004936487:11,341,663...11,393,275 JBrowse link
G Rftn1 raftlin, lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) UniProt PMID:19414744 MGI:3850290 NCBI chrNW_004936473:9,119,234...9,317,696 JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO (MGI:2176422|PMID:11894098)
(MGI:5285496|PMID:21469090)
MGI
UniProt
PMID:11894098 PMID:21469090 MGI:2176422 MGI:5285496 NCBI chrNW_004936544:3,606,925...3,653,248 JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chrNW_004936722:385,972...397,718 JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (MGI:5617929|PMID:24645804) MGI PMID:24645804 MGI:5617929 NCBI chrNW_004936524:5,698,101...5,832,801 JBrowse link
G Skap1 src kinase associated phosphoprotein 1 involved_in ISO (PMID:11909961) UniProt PMID:11909961 NCBI chrNW_004936490:12,885,443...13,213,409 JBrowse link
G Spn sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chrNW_004936501:12,773,967...12,776,642 JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in ISO (PMID:25384971)
(MGI:5640905|PMID:25384971)
UniProt PMID:25384971 MGI:5640905 NCBI chrNW_004936668:193,753...229,859 JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO (MGI:5003385|PMID:21487392) MGI PMID:21487392 MGI:5003385 NCBI chrNW_004936588:579,816...601,033 JBrowse link
G Stoml2 stomatin like 2 involved_in ISO (PMID:18641330) UniProt PMID:18641330 NCBI chrNW_004936524:3,129,149...3,132,405 JBrowse link
G Themis thymocyte selection associated involved_in ISO (MGI:4352756|PMID:19597499), (MGI:4352757|PMID:19597498) UniProt PMID:19597498 PMID:19597499 MGI:4352756 MGI:4352757 NCBI chrNW_004936639:1,739,380...1,915,545 JBrowse link
G Themis2 thymocyte selection associated family member 2 acts_upstream_of_or_within ISO (MGI:5446993|PMID:22732588) MGI PMID:22732588 MGI:5446993 NCBI chrNW_004936474:12,104,430...12,120,064 JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISO PMID:9285719 UniProt PMID:9285719 RGD:8554466 NCBI chrNW_004936542:4,323,905...4,329,940 JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO (MGI:2137821|PMID:11485735) UniProt PMID:11485735 MGI:2137821 NCBI chrNW_004936476:13,125,269...13,194,205 JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004936533:1,857,685...1,874,973 JBrowse link
G Txk TXK tyrosine kinase involved_in ISO (MGI:1335923|PMID:10213685) UniProt PMID:10213685 MGI:1335923 NCBI chrNW_004936482:14,190,409...14,231,690 JBrowse link
G Ube2n ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833
G Wnk1 WNK lysine deficient protein kinase 1 involved_in ISO (MGI:6141968|PMID:27400149) BHF-UCL PMID:27400149 MGI:6141968 NCBI chrNW_004936606:933,637...1,069,885 JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in ISO (MGI:5706909|PMID:23185455)
(MGI:6142401|PMID:25282160)
UniProt PMID:23185455 PMID:25282160 MGI:5706909 MGI:6142401 NCBI chrNW_004936474:19,714,145...19,722,512 JBrowse link
G Znf683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chrNW_004936474:10,851,249...10,859,092 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12173
    immune system process 1971
      activation of immune response 217
        activation of innate immune response + 31
        complement activation + 32
        immune response-activating signal transduction + 161
Path 2
Term Annotations click to browse term
  biological_process 12173
    biological regulation 8886
      regulation of biological process 8417
        positive regulation of biological process 5487
          positive regulation of response to stimulus 1888
            positive regulation of immune response 409
              activation of immune response 217
                activation of innate immune response + 31
                complement activation + 32
                immune response-activating signal transduction + 161
paths to the root