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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of immune response
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Accession:GO:0002253 term browser browse the term
Definition:Any process that initiates an immune response.



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activation of immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMSD histocompatibility minor serpin domain containing involved_in ISO (PMID:17409267) UniProt PMID:17409267 NCBI chr18:57,306,835...57,315,231 JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (MGI:3528786|PMID:15692051) MGI PMID:15692051 MGI:3528786 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773
JBrowse link
G TREX1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (MGI:3818783|PMID:18045533) MGI PMID:18045533 MGI:3818783 NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331
JBrowse link
activation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 involved_in ISO (PMID:19158675), (PMID:19158676), (PMID:19158679)
(MGI:3839523|PMID:19158676)
UniProt PMID:19158675 PMID:19158676 PMID:19158679 MGI:3839523 NCBI chr 1:134,413,232...134,540,344
Ensembl chr 1:138,210,946...138,221,753
JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in ISO (PMID:23258413)
(MGI:5505711|PMID:23929945), (MGI:5908326|PMID:24077100)
(MGI:5487472|PMID:23258413)
(PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:30007416)
UniProt PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More... MGI:5487472 MGI:5505711 MGI:5908326 NCBI chr 6:71,252,050...71,279,121
Ensembl chr 6:74,544,251...74,566,965
JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chr17:12,175,544...12,180,077
Ensembl chr17:12,353,590...12,354,669
JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:24971542) UniProt PMID:24971542 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:20628368) UniProt PMID:20628368 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in ISO (PMID:21575908) UniProt PMID:21575908 NCBI chr 1:134,364,706...134,405,910
Ensembl chr 1:138,152,328...138,203,424
JBrowse link
G MATR3 matrin 3 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chr 5:134,664,893...134,702,566 JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in ISO (PMID:18818105)
(PMID:20628368)
BHF-UCL
UniProt
PMID:18818105 PMID:20628368 NCBI chr20:3,885,044...3,903,554
Ensembl chr20:3,659,559...3,701,089
JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in ISO (MGI:3662990|PMID:16648852) UniProt PMID:16648852 MGI:3662990 NCBI chr2A:32,241,782...32,284,041
Ensembl chr2A:32,954,185...32,996,465
JBrowse link
G NONO non-POU domain containing octamer binding involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chr  X:60,547,277...60,564,845
Ensembl chr  X:70,602,456...70,619,956
JBrowse link
G PQBP1 polyglutamine binding protein 1 involved_in ISO (PMID:26046437) UniProt PMID:26046437 NCBI chr  X:41,188,244...41,200,312
Ensembl chr  X:49,053,030...49,058,585
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
G PSPC1 paraspeckle component 1 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chr13:1,001,131...1,106,627
Ensembl chr13:19,347,276...19,428,997
JBrowse link
G PYCARD PYD and CARD domain containing involved_in ISO (PMID:21575908)
(MGI:3839029|PMID:19158675)
UniProt PMID:19158675 PMID:21575908 MGI:3839029 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828
JBrowse link
G SFPQ splicing factor proline and glutamine rich involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chr 1:34,444,105...34,461,012
Ensembl chr 1:35,632,917...35,641,551
JBrowse link
G SIN3A SIN3 transcription regulator family member A involved_in ISO (PMID:22783022) BHF-UCL PMID:22783022 NCBI chr15:54,285,587...54,371,376
Ensembl chr15:73,881,500...73,966,506
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:18818105)
(MGI:5487473|PMID:23258412), (MGI:5487515|PMID:21947006)
BHF-UCL
UniProt
PMID:18818105 PMID:21947006 PMID:23258412 MGI:5487473 MGI:5487515 NCBI chr 5:134,845,689...134,852,938
Ensembl chr 5:140,967,399...140,973,846
JBrowse link
G TBK1 TANK binding kinase 1 acts_upstream_of_or_within ISO (MGI:3530402|PMID:15661922) MGI PMID:15661922 MGI:3530402 NCBI chr12:24,419,271...24,469,164
Ensembl chr12:24,917,246...24,968,587
JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within ISO (MGI:3530402|PMID:15661922) MGI PMID:15661922 MGI:3530402 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 involved_in ISO (PMID:20628368) UniProt PMID:20628368 NCBI chr 3:97,459,180...97,497,175
Ensembl chr 3:104,139,473...104,178,074
JBrowse link
G TRIM5 tripartite motif containing 5 involved_in ISO (PMID:21512573) UniProt PMID:21512573 NCBI chr11:5,798,336...5,819,876
Ensembl chr11:5,479,033...5,500,758
JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chr2B:103,371,459...103,468,419
Ensembl chr2B:221,972,742...222,071,235
JBrowse link
G XRCC6 X-ray repair cross complementing 6 involved_in ISO (PMID:28712728) UniProt PMID:28712728 NCBI chr22:22,516,281...22,557,379
Ensembl chr22:40,603,038...40,643,314
JBrowse link
G ZBP1 Z-DNA binding protein 1 involved_in ISO (MGI:6434626|PMID:32296175), (MGI:6436412|PMID:32200799) UniProt PMID:32200799 PMID:32296175 MGI:6434626 MGI:6436412 NCBI chr20:53,944,224...53,961,362
Ensembl chr20:55,222,405...55,239,130
JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in ISO (PMID:30135424), (PMID:30193849)
(MGI:6209107|PMID:30135424), (MGI:6271678|PMID:30193849)
UniProt PMID:30135424 PMID:30193849 MGI:6209107 MGI:6271678 NCBI chr20:504,967...508,354 JBrowse link
activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFH complement factor H acts_upstream_of_or_within ISO (MGI:4837299|PMID:20813971) MGI PMID:20813971 MGI:4837299 NCBI chr 1:172,155,882...172,251,632
Ensembl chr 1:176,455,247...176,525,521
JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:10587647) UniProt PMID:10587647 NCBI chr16:55,798,578...55,838,448
Ensembl chr16:75,150,122...75,188,775
JBrowse link
G CD19 CD19 molecule involved_in ISO (PMID:1373518) UniProt PMID:1373518 Ensembl chr16:29,320,734...29,327,481 JBrowse link
G LAX1 lymphocyte transmembrane adaptor 1 acts_upstream_of_or_within ISO (MGI:3578441|PMID:15843560) MGI PMID:15843560 MGI:3578441 NCBI chr 1:179,370,097...179,379,618
Ensembl chr 1:183,660,297...183,671,335
JBrowse link
G LOC100987922 SH2B adapter protein 2 acts_upstream_of_or_within ISO (MGI:1859033|PMID:10872802) MGI PMID:10872802 MGI:1859033
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:1927957|PMID:11120811), (MGI:3839222|PMID:19228876) MGI PMID:11120811 PMID:19228876 MGI:1927957 MGI:3839222 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941
JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:9020138) UniProt PMID:9020138 NCBI chr16:55,798,578...55,838,448
Ensembl chr16:75,150,122...75,188,775
JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:876631)
(PMID:23555801)
UniProt
ARUK-UCL
PMID:876631 PMID:23555801 NCBI chr 8:7,637,680...7,708,914 JBrowse link
G BLNK B cell linker involved_in ISO (PMID:9697839)
(PMID:11606584)
UniProt
ARUK-UCL
PMID:9697839 PMID:11606584 NCBI chr10:92,803,408...92,936,868
Ensembl chr10:96,316,103...96,391,067
JBrowse link
G BTK Bruton tyrosine kinase involved_in ISO (PMID:15509800) ARUK-UCL PMID:15509800 NCBI chr  X:90,551,874...90,588,786
Ensembl chr  X:100,684,017...100,725,187
JBrowse link
G CD19 CD19 molecule involved_in
acts_upstream_of_or_within
ISO (MGI:5476553|PMID:23499492)
(MGI:1095647|PMID:9254656)
UniProt
MGI
PMID:9254656 PMID:23499492 MGI:1095647 MGI:5476553 Ensembl chr16:29,320,734...29,327,481 JBrowse link
G CD38 CD38 molecule involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 4:10,228,803...10,295,129
Ensembl chr 4:15,525,835...15,587,677
JBrowse link
G CD79A CD79a molecule acts_upstream_of_or_within ISO (MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447) MGI PMID:1373499 PMID:8626447 MGI:3521842 MGI:79455 NCBI chr19:38,765,067...38,769,556
Ensembl chr19:47,270,377...47,274,711
JBrowse link
G CD79B CD79b molecule acts_upstream_of_or_within ISO (MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447) MGI PMID:1373499 PMID:8626447 MGI:3521842 MGI:79455 NCBI chr17:58,022,375...58,026,359
Ensembl chr17:63,116,722...63,120,335
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498
JBrowse link
G KLHL6 kelch like family member 6 involved_in ISO (MGI:3603885|PMID:16166635) UniProt PMID:16166635 MGI:3603885 NCBI chr 3:180,523,141...180,591,218
Ensembl chr 3:188,692,200...188,760,926
JBrowse link
G LAT2 linker for activation of T cells family member 2 involved_in ISO (PMID:12514734) HGNC-UCL PMID:12514734 Ensembl chr 7:81,350,666...81,377,115 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:77358|PMID:7499277) MGI PMID:7499277 MGI:77358 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923
JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within ISO (MGI:3769059|PMID:16249387) MGI PMID:16249387 MGI:3769059
G LYN LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253)
(MGI:77358|PMID:7499277)
MGI PMID:7499277 PMID:23509253 MGI:5471851 MGI:77358 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:1095647|PMID:9254656) MGI PMID:9254656 MGI:1095647 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (MGI:3829850|PMID:18955699) UniProt PMID:18955699 MGI:3829850 NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426
JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 1:134,190,768...134,208,723
Ensembl chr 1:137,992,523...137,999,587
JBrowse link
G MS4A1 membrane spanning 4-domains A1 involved_in ISO (PMID:18474602) UniProt PMID:18474602 NCBI chr11:55,691,750...55,706,697
Ensembl chr11:59,134,617...59,149,521
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 acts_upstream_of_or_within ISO (MGI:3044463|PMID:15143214) MGI PMID:15143214 MGI:3044463 NCBI chr22:23,276,675...23,332,932
Ensembl chr22:41,345,206...41,396,721
JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr20:47,734,054...47,910,435
Ensembl chr20:48,858,238...49,034,007
JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in ISO (MGI:1861532|PMID:10925250)
(PMID:15509800)
(PMID:11606584)
UniProt
ARUK-UCL
PMID:10925250 PMID:11606584 PMID:15509800 MGI:1861532 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064
JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 involved_in ISO (PMID:12101241) UniProt PMID:12101241 NCBI chr10:118,942,896...119,001,185
Ensembl chr10:122,354,765...122,412,588
JBrowse link
G PRKCB protein kinase C beta involved_in ISO (MGI:3626015|PMID:12118249) UniProt PMID:12118249 MGI:3626015 NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253)
(MGI:1095647|PMID:9254656)
MGI PMID:9254656 PMID:23509253 MGI:1095647 MGI:5471851 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in
ISO (MGI:1095647|PMID:9254656)
(MGI:77358|PMID:7499277)
(MGI:3687418|PMID:8692271)
MGI
UniProt
PMID:7499277 PMID:8692271 PMID:9254656 MGI:1095647 MGI:3687418 MGI:77358 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in ISO (PMID:12805216) UniProt PMID:12805216 NCBI chr 3:16,241,255...16,441,402
Ensembl chr 3:16,578,092...16,778,464
JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in ISO (PMID:9233773) UniProt PMID:9233773 NCBI chr 7:94,425,297...94,447,644 JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in
ISO (MGI:77358|PMID:7499277), (MGI:79455|PMID:8626447)
(PMID:15509800)
MGI
ARUK-UCL
PMID:7499277 PMID:8626447 PMID:15509800 MGI:77358 MGI:79455 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101
JBrowse link
G TEC tec protein tyrosine kinase involved_in ISO (PMID:10518561) UniProt PMID:10518561 NCBI chr 4:73,885,588...74,018,061
Ensembl chr 4:84,618,088...84,750,319
JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 1:110,101,651...110,531,294
Ensembl chr 1:109,210,813...109,617,658
JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) MGI PMID:12719478 MGI:3042099 NCBI chr12:10,161,780...10,174,943
Ensembl chr12:10,410,384...10,425,452
JBrowse link
G FCN1 ficolin 1 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr 9:106,039,315...106,047,648
Ensembl chr 9:135,040,310...135,049,111
JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr19:32,394,401...32,398,730
Ensembl chr19:41,132,599...41,133,591
JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) MGI PMID:12719478 MGI:3042099 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331
JBrowse link
complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2 complement C2 involved_in ISO (PMID:19302245) BHF-UCL PMID:19302245 NCBI chr 6:31,590,135...31,606,368 JBrowse link
G C3 complement C3 acts_upstream_of_or_within
involved_in
ISO (MGI:3833206|PMID:18947875)
(MGI:5617896|PMID:25284781)
(PMID:19302245)
RGD
MGI
BHF-UCL
PMID:18947875 PMID:19302245 PMID:20712003 PMID:25284781 MGI:3833206 MGI:5617896 RGD:5129529 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G C8A complement C8 alpha chain acts_upstream_of_or_within ISO (PMID:12413696) MGI PMID:12413696 NCBI chr 1:56,137,596...56,201,975
Ensembl chr 1:57,847,726...57,912,392
JBrowse link
G CFB complement factor B ISO RGD PMID:6906329 RGD:2311339 NCBI chr 6:31,606,716...31,612,782 JBrowse link
G CFH complement factor H acts_upstream_of_or_within
involved_in
ISO (MGI:3848672|PMID:19411110), (MGI:4821502|PMID:20675597)
(MGI:3639077|PMID:15574507), (MGI:3760048|PMID:17517971), (MGI:3760334|PMID:17921253), (MGI:3849508|PMID:19541934), (MGI:5883383|PMID:28057640)
(MGI:4830025|PMID:20702729)
(PMID:24835392)
RGD
MGI
AgBase
PMID:12911541 PMID:15574507 PMID:17517971 PMID:17921253 PMID:19411110 More... MGI:3639077 MGI:3760048 MGI:3760334 MGI:3848672 MGI:3849508 MGI:4821502 MGI:4830025 MGI:5883383 RGD:1599888 NCBI chr 1:172,155,882...172,251,632
Ensembl chr 1:176,455,247...176,525,521
JBrowse link
G CFI complement factor I involved_in ISO (MGI:3773599|PMID:18202746) MGI PMID:18202746 MGI:3773599 NCBI chr 4:102,236,868...102,311,359
Ensembl chr 4:112,804,645...112,865,581
JBrowse link
G COLEC11 collectin subfamily member 11 involved_in ISO (PMID:23954398) UniProt PMID:23954398 NCBI chr2A:3,610,679...3,659,739
Ensembl chr2A:3,529,358...3,579,517
JBrowse link
G CR1L complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (MGI:4821502|PMID:20675597) MGI PMID:20675597 MGI:4821502 NCBI chr 1:183,224,415...183,303,268
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G FCN3 ficolin 3 involved_in ISO (PMID:22851708) UniProt PMID:22851708 NCBI chr 1:26,620,373...26,636,424
Ensembl chr 1:27,676,866...27,683,861
JBrowse link
G RGCC regulator of cell cycle involved_in ISO (PMID:19162005) BHF-UCL PMID:19162005 NCBI chr13:22,639,289...22,652,594
Ensembl chr13:41,228,643...41,241,909
JBrowse link
complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFB complement factor B acts_upstream_of_or_within ISO (MGI:1096110|PMID:9238044)
(MGI:6100611|PMID:27564415)
MGI PMID:9238044 PMID:27564415 MGI:1096110 MGI:6100611 NCBI chr 6:31,606,716...31,612,782 JBrowse link
G CFH complement factor H acts_upstream_of_or_within
acts_upstream_of_or_within_negative_effect
ISO (MGI:6100611|PMID:27564415)
(MGI:4421084|PMID:19828624)
MGI PMID:19828624 PMID:27564415 MGI:4421084 MGI:6100611 NCBI chr 1:172,155,882...172,251,632
Ensembl chr 1:176,455,247...176,525,521
JBrowse link
G CFP complement factor properdin involved_in ISO (MGI:3773929|PMID:18292556) MGI PMID:18292556 MGI:3773929 NCBI chr  X:40,060,106...40,066,720
Ensembl chr  X:47,956,191...47,961,965
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G CR2 complement C3d receptor 2 involved_in
acts_upstream_of_or_within_negative_effect
ISO (PMID:11981823)
(MGI:4421084|PMID:19828624)
ARUK-UCL
MGI
PMID:11981823 PMID:19828624 MGI:4421084 NCBI chr 1:183,052,798...183,088,385
Ensembl chr 1:187,330,483...187,366,069
JBrowse link
complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRP C-reactive protein ISO RGD PMID:16367929 RGD:1580273 NCBI chr 1:135,062,102...135,064,402 JBrowse link
complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COLEC11 collectin subfamily member 11 involved_in ISO (PMID:25912189) UniProt PMID:25912189 NCBI chr2A:3,610,679...3,659,739
Ensembl chr2A:3,529,358...3,579,517
JBrowse link
G FCN2 ficolin 2 involved_in ISO (PMID:14707097), (PMID:15804047) UniProt PMID:14707097 PMID:15804047 NCBI chr 9:105,995,807...106,020,389
Ensembl chr 9:134,997,038...135,018,992
JBrowse link
G FCN3 ficolin 3 involved_in
acts_upstream_of_or_within
ISO (PMID:11907111)
(MGI:5473786|PMID:16328467)
UniProt
MGI
PMID:11907111 PMID:16328467 MGI:5473786 NCBI chr 1:26,620,373...26,636,424
Ensembl chr 1:27,676,866...27,683,861
JBrowse link
G LOC100970659 keratin, type II cytoskeletal 1 involved_in ISO (PMID:11549596) UniProt PMID:11549596 NCBI chr12:36,083,858...36,089,521
Ensembl chr12:36,861,585...36,866,725
JBrowse link
G MASP1 MBL associated serine protease 1 involved_in ISO (PMID:17182967)
(MGI:3789229|PMID:18424734)
UniProt PMID:17182967 PMID:18424734 MGI:3789229 NCBI chr 3:184,241,611...184,317,272
Ensembl chr 3:192,707,784...192,782,196
JBrowse link
G MASP2 MBL associated serine protease 2 involved_in
acts_upstream_of_or_within
ISO (PMID:17182967), (PMID:9087411)
(MGI:5473786|PMID:16328467)
UniProt
MGI
PMID:9087411 PMID:16328467 PMID:17182967 MGI:5473786 NCBI chr 1:9,787,565...9,810,276
Ensembl chr 1:11,009,760...11,030,734
JBrowse link
G MBL2 mannose binding lectin 2 involved_in
acts_upstream_of_or_within
ISO (PMID:11549596)
(PMID:15148336)
(MGI:3577322|PMID:15148336)
UniProt
MGI
PMID:11549596 PMID:15148336 MGI:3577322 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5AR1 complement C5a receptor 1 involved_in ISO (PMID:10571060) UniProt PMID:10571060 NCBI chr19:44,293,612...44,310,430
Ensembl chr19:52,950,317...52,966,146
JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3AR1 complement C3a receptor 1 involved_in ISO (PMID:10571060) UniProt PMID:10571060 NCBI chr12:8,178,064...8,186,206
Ensembl chr12:8,220,933...8,222,381
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:16360013), (PMID:22962438) ARUK-UCL PMID:16360013 PMID:22962438 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:15907827), (PMID:19135435) UniProt PMID:15907827 PMID:19135435 NCBI chr 6:24,257,923...24,332,171
Ensembl chr 6:24,588,672...24,665,229
JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:3703139|PMID:16272347) UniProt PMID:16272347 MGI:3703139 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287
JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR2B Fc fragment of IgG receptor IIb involved_in ISO (PMID:2142460) ARUK-UCL PMID:2142460 NCBI chr 1:137,074,342...137,090,962 JBrowse link
G MYO1G myosin IG involved_in ISO (MGI:5586792|PMID:23038771) UniProt PMID:23038771 MGI:5586792 NCBI chr 7:45,676,225...45,693,013
Ensembl chr 7:45,740,036...45,759,819
JBrowse link
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG6 BAG cochaperone 6 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321
JBrowse link
G MICB MHC class I polypeptide-related sequence B involved_in ISO (PMID:11491531) UniProt PMID:11491531 NCBI chr 6:31,151,935...31,167,567 JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chr 6:31,249,947...31,281,613
Ensembl chr 6:32,139,981...32,171,525
JBrowse link
immune response-activating signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZC3H12A zinc finger CCCH-type containing 12A involved_in ISO (PMID:19909337) UniProt PMID:19909337 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
innate immune response-activating signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TLR4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050) RGD
MGI
PMID:10946279 PMID:11471050 PMID:15843577 MGI:1888643 MGI:2148385 RGD:1600482 NCBI chr11:33,680,580...33,708,479
Ensembl chr11:33,552,164...33,590,157
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) acts_upstream_of ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 1:183,094,601...183,246,957 JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD22 CD22 molecule involved_in ISO (PMID:26017478)
(PMID:24169826)
ARUK-UCL PMID:24169826 PMID:26017478 NCBI chr19:32,265,278...32,294,122
Ensembl chr19:41,012,222...41,030,713
JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928
JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr 1:137,074,342...137,090,962 JBrowse link
G FCRL3 Fc receptor like 3 involved_in ISO (PMID:19843936) UniProt PMID:19843936 NCBI chr 1:133,038,100...133,062,467
Ensembl chr 1:136,830,553...136,855,027
JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253) MGI PMID:23509253 MGI:5471851 NCBI chr 1:132,875,598...132,915,018
Ensembl chr 1:136,666,603...136,785,242
JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) UniProt PMID:28039360 MGI:5896692 NCBI chr17:7,346,766...7,349,682
Ensembl chr17:7,333,571...7,335,871
JBrowse link
G LPXN leupaxin involved_in ISO (PMID:17640867)
(MGI:3722965|PMID:17640867)
UniProt PMID:17640867 MGI:3722965 NCBI chr11:53,781,270...53,832,785
Ensembl chr11:57,243,028...57,293,442
JBrowse link
G PLCL2 phospholipase C like 2 acts_upstream_of_or_within ISO (MGI:2677607|PMID:14517301) MGI PMID:14517301 MGI:2677607 NCBI chr 3:16,736,430...17,015,531
Ensembl chr 3:17,154,500...17,351,287
JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:6211481)
(PMID:28657829)
RGD
UniProt
PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chr 1:182,923,369...182,962,518
Ensembl chr 1:187,201,081...187,240,350
JBrowse link
G CD59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (MGI:1888643|PMID:10946279) MGI PMID:10946279 MGI:1888643 NCBI chr11:33,680,580...33,708,479
Ensembl chr11:33,552,164...33,590,157
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G CR1L complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (MGI:1351571|PMID:10642554) RGD
MGI
PMID:10642554 PMID:11861390 MGI:1351571 RGD:625470 NCBI chr 1:183,224,415...183,303,268
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G MASP1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) UniProt PMID:11485744 NCBI chr 3:184,241,611...184,317,272
Ensembl chr 3:192,707,784...192,782,196
JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:10531307) UniProt PMID:10531307 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr 1:198,899,771...199,043,215
Ensembl chr 1:203,911,484...204,054,448
JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 involved_in ISO (PMID:17051150) UniProt PMID:17051150 NCBI chr  X:55,137,938...55,155,569
Ensembl chr  X:65,211,313...65,229,332
JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 1:182,707,221...182,747,878
Ensembl chr 1:186,985,264...187,025,898
JBrowse link
G C4BPB complement component 4 binding protein beta involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 1:182,691,574...182,703,004
Ensembl chr 1:186,970,253...186,981,024
JBrowse link
G CD46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:10531307), (PMID:6910481) UniProt PMID:6910481 PMID:10531307 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr 1:198,899,771...199,043,215
Ensembl chr 1:203,911,484...204,054,448
JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPING1 serpin family G member 1 involved_in ISO (PMID:10946292) UniProt PMID:10946292 NCBI chr11:52,838,502...52,855,781
Ensembl chr11:56,309,686...56,326,639
JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chr 3:57,161,299...57,206,672
Ensembl chr 3:58,370,430...58,415,258
JBrowse link
G CD47 CD47 molecule involved_in ISO PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr 3:105,170,246...105,217,603
Ensembl chr 3:112,104,037...112,143,522
JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTN2A2 butyrophilin subfamily 2 member A2 acts_upstream_of_or_within ISO (MGI:5520006|PMID:23589618) MGI PMID:23589618 MGI:5520006 NCBI chr 6:26,215,215...26,227,261
Ensembl chr 6:26,873,828...26,885,592
JBrowse link
G BTNL2 butyrophilin like 2 acts_upstream_of_or_within ISO (MGI:3775536|PMID:16751379) MGI PMID:16751379 MGI:3775536 NCBI chr 6:32,067,223...32,126,032 JBrowse link
G CBLB Cbl proto-oncogene B acts_upstream_of_or_within ISO (MGI:3041371|PMID:14738763) MGI PMID:14738763 MGI:3041371 NCBI chr 3:102,752,406...102,966,414
Ensembl chr 3:109,690,120...109,905,191
JBrowse link
G CD160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chr 1:122,025,605...122,031,980
Ensembl chr 1:113,636,195...113,646,491
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739
JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISO (MGI:2672999|PMID:12883552) UniProt PMID:12883552 MGI:2672999 NCBI chr11:46,291,592...46,339,127
Ensembl chr11:46,841,605...46,889,763
JBrowse link
G DUSP22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:5583944|PMID:24714587) MGI PMID:24714587 MGI:5583944 NCBI chr 6:107,145...180,777
Ensembl chr 6:242,121...301,248
JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in ISO (PMID:12447358) UniProt PMID:12447358 NCBI chr17:13,618,860...13,631,743
Ensembl chr17:13,784,594...13,797,045
JBrowse link
G ELF1 E74 like ETS transcription factor 1 acts_upstream_of_or_within ISO (MGI:3041371|PMID:14738763) MGI PMID:14738763 MGI:3041371 NCBI chr13:22,136,952...22,263,523
Ensembl chr13:40,726,930...40,774,734
JBrowse link
G EZR ezrin involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chr 6:156,656,146...156,709,986
Ensembl chr 6:161,670,483...161,723,102
JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) ARUK-UCL PMID:18619870 MGI:3803048 NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385
JBrowse link
G LGALS3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chr14:35,715,850...35,732,263
Ensembl chr14:53,990,023...54,006,412
JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:22387553)
(PMID:16493035)
BHF-UCL
ARUK-UCL
PMID:16493035 PMID:22387553 NCBI chr19:51,606,681...51,612,751 JBrowse link
G PAWR pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO (MGI:2675524|PMID:12970181) MGI PMID:12970181 MGI:2675524 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796
JBrowse link
G PHPT1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chr 9:107,906,160...107,908,130 JBrowse link
G PRNP prion protein involved_in ISO (MGI:4943618|PMID:20145049) BHF-UCL PMID:20145049 MGI:4943618 NCBI chr20:4,713,616...4,728,847
Ensembl chr20:4,523,155...4,523,916
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:5320871|PMID:22080863) UniProt PMID:22080863 MGI:5320871 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:82729|PMID:9064344) MGI PMID:9064344 MGI:82729 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (PMID:11259588), (PMID:9780142)
(MGI:4942249|PMID:12913111)
(PMID:12913111)
UniProt PMID:9780142 PMID:11259588 PMID:12913111 MGI:4942249 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494
JBrowse link
G PVRIG PVR related immunoglobulin domain containing involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chr 7:92,254,639...92,256,592
Ensembl chr 7:105,687,005...105,689,674
JBrowse link
G SH2D1A SH2 domain containing 1A involved_in ISO (PMID:9774102) UniProt PMID:9774102 NCBI chr  X:113,538,321...113,565,468
Ensembl chr  X:123,712,932...123,739,419
JBrowse link
G SLA2 Src like adaptor 2 involved_in ISO (PMID:11891219) UniProt PMID:11891219 NCBI chr20:32,945,409...32,978,966
Ensembl chr20:34,065,385...34,098,581
JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISO (MGI:1096761|PMID:9285719) UniProt PMID:9285719 MGI:1096761 NCBI chr11:114,253,535...114,259,495
Ensembl chr11:118,180,717...118,186,901
JBrowse link
G UBASH3A ubiquitin associated and SH3 domain containing A acts_upstream_of_or_within ISO (MGI:3041371|PMID:14738763) MGI PMID:14738763 MGI:3041371 NCBI chr21:28,711,107...28,755,405
Ensembl chr21:42,029,709...42,073,746
JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:69,174,411...69,245,801
Ensembl chr 5:74,216,244...74,288,588
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chr 1:183,094,601...183,246,957 JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3687418|PMID:8692271) UniProt PMID:8692271 MGI:3687418 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in ISO (PMID:20237408)
(MGI:5476553|PMID:23499492)
UniProt PMID:20237408 PMID:23499492 MGI:5476553 NCBI chr11:2,400,503...2,421,132
Ensembl chr11:2,437,991...2,449,308
JBrowse link
G CMTM3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (MGI:3047050|PMID:15196959) MGI PMID:15196959 MGI:3047050 NCBI chr16:46,920,341...46,930,047
Ensembl chr16:66,022,698...66,031,525
JBrowse link
G FOXP1 forkhead box P1 involved_in ISO (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in ISO (MGI:3044463|PMID:15143214) HGNC-UCL PMID:15143214 MGI:3044463 NCBI chr22:23,276,675...23,332,932
Ensembl chr22:41,345,206...41,396,721
JBrowse link
G PRKCB protein kinase C beta involved_in ISO (MGI:3700457|PMID:16301747) UniProt PMID:16301747 MGI:3700457 NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203
JBrowse link
G PRKCH protein kinase C eta involved_in ISO (PMID:18780722) UniProt PMID:18780722 NCBI chr14:41,882,022...42,151,305
Ensembl chr14:60,179,081...60,408,251
JBrowse link
G SLC39A10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO (MGI:5586914|PMID:25074919) MGI PMID:25074919 MGI:5586914 NCBI chr2B:82,823,472...82,981,894
Ensembl chr2B:200,805,459...200,883,524
JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in ISO (PMID:10518561) BHF-UCL PMID:10518561 NCBI chr 4:56,442,773...56,491,148
Ensembl chr 4:62,836,288...62,882,570
JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:69,174,411...69,245,801
Ensembl chr 5:74,216,244...74,288,588
JBrowse link
G IL1B interleukin 1 beta involved_in ISO (PMID:29384235) ARUK-UCL PMID:29384235 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G MBL2 mannose binding lectin 2 ISO RGD PMID:9920905 RGD:4889148 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G PHB prohibitin involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790
JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6275756|PMID:30548312) ARUK-UCL PMID:30548312 MGI:6275756 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578
JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in ISO (PMID:16831868) BHF-UCL PMID:16831868 NCBI chr18:63,238,477...63,379,346
Ensembl chr18:66,533,949...66,627,580
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287
JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chr12:102,755,388...102,818,686
Ensembl chr12:106,151,969...106,206,879
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664
JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chr 9:70,907,056...70,950,221 JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within ISO (MGI:3640996|PMID:11435465) MGI PMID:11435465 MGI:3640996 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868
JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chr 1:117,823,388...117,834,314 JBrowse link
G CARD11 caspase recruitment domain family member 11 involved_in ISO (PMID:12154360)
(MGI:6695669|PMID:12154356)
UniProt PMID:12154356 PMID:12154360 MGI:6695669 NCBI chr 7:3,166,788...3,304,729
Ensembl chr 7:3,258,736...3,332,999
JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3847607|PMID:17785582) BHF-UCL PMID:17785582 MGI:3847607 NCBI chr17:16,720,236...16,731,955
Ensembl chr17:16,949,119...16,956,370
JBrowse link
G CD226 CD226 molecule involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chr18:63,238,477...63,379,346
Ensembl chr18:66,533,949...66,627,580
JBrowse link
G CD81 CD81 molecule involved_in ISO (PMID:23858057) UniProt PMID:23858057 NCBI chr11:2,400,503...2,421,132
Ensembl chr11:2,437,991...2,449,308
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (MGI:3656194|PMID:16501569) MGI PMID:16501569 MGI:3656194 NCBI chr16:31,004,393...31,064,546
Ensembl chr16:49,882,751...49,942,629
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chr  X:143,988,720...144,010,078
Ensembl chr  X:153,854,493...153,876,092
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chr19:40,715,621...40,735,025
Ensembl chr19:49,321,403...49,335,900
JBrowse link
G LOC100990994 T-cell receptor-associated transmembrane adapter 1 acts_upstream_of_or_within ISO (PMID:11390434) MGI PMID:11390434 NCBI chr 3:105,948,998...105,981,111
Ensembl chr 3:112,879,355...112,911,668
JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chr19:41,794,037...41,837,047
Ensembl chr19:50,399,668...50,443,024
JBrowse link
G PRKD2 protein kinase D2 involved_in ISO (MGI:4849903|PMID:20819079) UniProt PMID:20819079 MGI:4849903 NCBI chr19:43,666,591...43,710,858
Ensembl chr19:52,195,303...52,237,731
JBrowse link
G RAB29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) ParkinsonsUK-UCL PMID:26021297 NCBI chr 1:181,377,018...181,384,496
Ensembl chr 1:185,661,317...185,668,066
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in ISO (MGI:5432321|PMID:22561606) UniProt PMID:22561606 MGI:5432321 NCBI chr12:33,765,283...33,800,883
Ensembl chr12:34,492,311...34,527,627
JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD19 CD19 molecule involved_in ISO (PMID:9382888)
(MGI:1100180|PMID:9382888)
UniProt PMID:9382888 MGI:1100180 Ensembl chr16:29,320,734...29,327,481 JBrowse link
G GCSAM germinal center associated signaling and motility involved_in ISO (PMID:23299888) UniProt PMID:23299888 NCBI chr 3:109,263,708...109,279,715 JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:2152233|PMID:11672542) UniProt PMID:11672542 MGI:2152233 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287
JBrowse link
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in ISO (PMID:8195709) UniProt PMID:8195709 NCBI chr17:5,481,114...5,487,482
Ensembl chr17:5,473,239...5,479,735
JBrowse link
G CD55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chr 1:182,923,369...182,962,518
Ensembl chr 1:187,201,081...187,240,350
JBrowse link
G CD59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chr11:33,680,580...33,708,479
Ensembl chr11:33,552,164...33,590,157
JBrowse link
G CD5L CD5 molecule like acts_upstream_of_or_within ISO (MGI:5617896|PMID:25284781) MGI PMID:25284781 MGI:5617896 NCBI chr 1:133,192,387...133,203,293
Ensembl chr 1:136,985,701...136,996,263
JBrowse link
G CFH complement factor H acts_upstream_of_or_within ISO (PMID:25284781)
(MGI:3833206|PMID:18947875)
RGD
MGI
PMID:12374811 PMID:18947875 PMID:25284781 MGI:3833206 RGD:628500 NCBI chr 1:172,155,882...172,251,632
Ensembl chr 1:176,455,247...176,525,521
JBrowse link
G CR1L complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (MGI:3833206|PMID:18947875)
(PMID:25284781)
MGI PMID:18947875 PMID:25284781 MGI:3833206 NCBI chr 1:183,224,415...183,303,268
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G PHB2 prohibitin 2 NOT|involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr 1:198,899,771...199,043,215
Ensembl chr 1:203,911,484...204,054,448
JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (MGI:1330710|PMID:9892684) MGI PMID:9892684 MGI:1330710 NCBI chr 1:182,923,369...182,962,518
Ensembl chr 1:187,201,081...187,240,350
JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSK C-terminal Src kinase ISO RGD PMID:9325302 RGD:2303720 NCBI chr15:53,724,814...53,745,710
Ensembl chr15:73,342,703...73,363,476
JBrowse link
G LOC100993573 rab5 GDP/GTP exchange factor acts_upstream_of_or_within ISO (MGI:3050742|PMID:15235600)
(MGI:3834538|PMID:17341663)
MGI PMID:15235600 PMID:17341663 MGI:3050742 MGI:3834538 NCBI chr 7:59,268,053...59,344,555
Ensembl chr 7:73,775,002...73,850,446
JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISO PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr 3:143,528,967...143,558,468
Ensembl chr 3:151,112,483...151,132,964
JBrowse link
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR2A Fc fragment of IgG receptor IIa ISO RGD PMID:16482158 PMID:22184119 RGD:11041001 RGD:2293335 NCBI chr 1:136,892,311...136,906,450 JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:3629264 NCBI chr 1:117,823,388...117,834,314 JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:22046970) UniProt PMID:22046970 NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:3042327|PMID:14752163) MGI PMID:14752163 MGI:3042327 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923
JBrowse link
G MALT1 MALT1 paracaspase acts_upstream_of_or_within ISO (MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:3629264 NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:3580753|PMID:15917799) BHF-UCL PMID:15917799 MGI:3580753 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (MGI:5920164|PMID:28598420) MGI PMID:28598420 MGI:5920164 NCBI chr12:33,765,283...33,800,883
Ensembl chr12:34,492,311...34,527,627
JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC6A C-type lectin domain containing 6A involved_in ISO (MGI:5300086|PMID:22041900) ARUK-UCL PMID:22041900 MGI:5300086 NCBI chr12:8,537,766...8,560,736
Ensembl chr12:8,752,778...8,775,738
JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr12:10,277,685...10,364,056
Ensembl chr12:10,598,705...10,606,547
JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in ISO (MGI:3844414|PMID:19136564), (MGI:5300086|PMID:22041900) ARUK-UCL PMID:19136564 PMID:22041900 MGI:3844414 MGI:5300086 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064
JBrowse link
G SYK spleen associated tyrosine kinase involved_in ISO (MGI:3844414|PMID:19136564) ARUK-UCL PMID:19136564 MGI:3844414 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr19:32,821,279...32,825,488
Ensembl chr19:41,570,683...41,575,226
JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr19:32,821,279...32,825,488
Ensembl chr19:41,570,683...41,575,226
JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:3798766|PMID:18305217) MGI PMID:18305217 MGI:3798766 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941
JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr 1:117,823,388...117,834,314 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:3773982|PMID:18228248) MGI PMID:18228248 MGI:3773982 NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115
JBrowse link
G BTN3A1 butyrophilin subfamily 3 member A1 involved_in ISO (PMID:21918970) UniProt PMID:21918970 NCBI chr 6:26,234,632...26,247,612
Ensembl chr 6:26,892,960...26,905,915
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within ISO (MGI:3691409|PMID:17028169) MGI PMID:17028169 MGI:3691409 NCBI chr12:39,918,022...39,931,386
Ensembl chr12:40,797,293...40,811,409
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO (MGI:3526783|PMID:15637280), (MGI:3691409|PMID:17028169) MGI PMID:15637280 PMID:17028169 MGI:3526783 MGI:3691409 NCBI chr2B:39,137,777...39,399,007 JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (MGI:5544872|PMID:23793062) MGI PMID:23793062 MGI:5544872 NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709
JBrowse link
G CBLB Cbl proto-oncogene B acts_upstream_of_or_within ISO (MGI:2665211|PMID:12697763) MGI PMID:12697763 MGI:2665211 NCBI chr 3:102,752,406...102,966,414
Ensembl chr 3:109,690,120...109,905,191
JBrowse link
G CD247 CD247 molecule acts_upstream_of_or_within ISO (MGI:3640996|PMID:11435465) MGI PMID:11435465 MGI:3640996 NCBI chr 1:142,863,860...142,951,851
Ensembl chr 1:146,648,733...146,736,071
JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within ISO (MGI:5544872|PMID:23793062) MGI PMID:23793062 MGI:5544872 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213
JBrowse link
G CD3E CD3e molecule acts_upstream_of_or_within ISO (MGI:3577956|PMID:10485657) MGI PMID:10485657 MGI:3577956 NCBI chr11:113,142,200...113,153,928
Ensembl chr11:117,074,041...117,085,625
JBrowse link
G CLEC2A C-type lectin domain family 2 member A acts_upstream_of_or_within ISO (MGI:3622591|PMID:16143319) MGI PMID:16143319 MGI:3622591 NCBI chr12:9,959,826...9,981,376
Ensembl chr12:10,195,862...10,229,273
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (MGI:3798766|PMID:18305217) MGI PMID:18305217 MGI:3798766 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858
JBrowse link
G DENND1B DENN domain containing 1B involved_in ISO (PMID:26774822)
(MGI:5751612|PMID:26774822)
UniProt PMID:26774822 MGI:5751612 NCBI chr 1:173,102,371...173,365,024
Ensembl chr 1:177,420,565...177,676,293
JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chr12:121,206,380...121,218,749
Ensembl chr12:125,433,227...125,446,665
JBrowse link
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chr14:55,554,516...55,561,201
Ensembl chr14:74,399,056...74,405,770
JBrowse link
G EIF2B3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chr 1:44,154,600...44,290,407
Ensembl chr 1:45,525,137...45,650,259
JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chr2A:27,368,189...27,374,265
Ensembl chr2A:27,456,457...27,462,706
JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chr 3:181,170,806...181,180,923
Ensembl chr 3:189,652,554...189,665,528
JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within ISO (MGI:1331533|PMID:10072494), (MGI:1929588|PMID:11265635) MGI PMID:10072494 PMID:11265635 MGI:1331533 MGI:1929588 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G FYB2 FYN binding protein 2 involved_in ISO (PMID:27335501) UniProt PMID:27335501 NCBI chr 1:56,002,100...56,077,222
Ensembl chr 1:57,712,240...57,812,447
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:7722293) UniProt PMID:7722293 NCBI chr 6:109,469,750...109,684,086
Ensembl chr 6:113,545,944...113,604,451
JBrowse link
G GATA3 GATA binding protein 3 involved_in ISO (MGI:5285154|PMID:20696860) UniProt PMID:20696860 MGI:5285154 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G HRAS HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G ITK IL2 inducible T cell kinase involved_in ISO (MGI:1335923|PMID:10213685) UniProt PMID:10213685 MGI:1335923 NCBI chr 5:152,582,125...152,656,211
Ensembl chr 5:159,204,016...159,277,689
JBrowse link
G KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISO (PMID:9045636) UniProt PMID:9045636 NCBI chr 1:31,297,843...31,345,148
Ensembl chr 1:32,312,598...32,342,582
JBrowse link
G LCP2 lymphocyte cytosolic protein 2 involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chr 5:165,605,590...165,655,378
Ensembl chr 5:172,365,794...172,414,585
JBrowse link
G LOC100971372 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within ISO (MGI:893249|PMID:9208839) MGI PMID:9208839 MGI:893249 NCBI chr2A:101,582,567...101,613,175
Ensembl chr2A:98,613,740...98,639,088
JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272
JBrowse link
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387
JBrowse link
G MALT1 MALT1 paracaspase involved_in ISO (PMID:15125833)
(MGI:6142401|PMID:25282160)
UniProt PMID:15125833 PMID:25282160 MGI:6142401 NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:82729|PMID:9064344) MGI PMID:9064344 MGI:82729 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr19:32,805,772...32,817,778
Ensembl chr19:41,553,727...41,568,555
JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 3:98,914,957...98,948,467
Ensembl chr 3:105,616,645...105,628,300
JBrowse link
G NRAS NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chr 1:87,837,146...87,850,013
Ensembl chr 1:122,890,505...122,903,585
JBrowse link
G PDE4B phosphodiesterase 4B involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chr 1:65,038,120...65,620,764
Ensembl chr 1:67,045,911...67,506,291
JBrowse link
G PDE4D phosphodiesterase 4D involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111
JBrowse link
G PLCG1 phospholipase C gamma 1 acts_upstream_of_or_within ISO (MGI:3531056|PMID:15728238) MGI PMID:15728238 MGI:3531056 NCBI chr20:37,477,077...37,515,854
Ensembl chr20:38,572,709...38,615,145
JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (MGI:3531056|PMID:15728238) MGI PMID:15728238 MGI:3531056 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064
JBrowse link
G PRKD2 protein kinase D2 involved_in ISO (PMID:17077180) BHF-UCL PMID:17077180 NCBI chr19:43,666,591...43,710,858
Ensembl chr19:52,195,303...52,237,731
JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within ISO (MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:3760494 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:3760494 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 acts_upstream_of_or_within ISO (MGI:3042327|PMID:14752163) MGI PMID:14752163 MGI:3042327 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISO PMID:12496963
(MGI:6201809|PMID:12496963)
(PMID:10358156)
ARUK-UCL
UniProt
PMID:10358156 PMID:12496963 MGI:6201809 RGD:1358565 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chr20:615,987...639,366
Ensembl chr20:386,569...409,580
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 9:93,975,164...94,031,516
Ensembl chr 9:122,313,791...122,365,102
JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) UniProt PMID:19414744 MGI:3850290 NCBI chr 3:16,241,255...16,441,402
Ensembl chr 3:16,578,092...16,778,464
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within
ISO (MGI:5285496|PMID:21469090)
(MGI:2176422|PMID:11894098)
UniProt
MGI
PMID:11894098 PMID:21469090 MGI:2176422 MGI:5285496 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268
JBrowse link
G RNF31 ring finger protein 31 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chr14:4,923,391...4,936,959 JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (MGI:5617929|PMID:24645804) MGI PMID:24645804 MGI:5617929 NCBI chr 9:37,768,566...37,921,897 JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 involved_in ISO (PMID:11909961) UniProt PMID:11909961 NCBI chr17:9,079,452...9,402,192
Ensembl chr17:9,290,929...9,581,253
JBrowse link
G SPN sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 Ensembl chr16:30,035,243...30,036,445 JBrowse link
G SPPL3 signal peptide peptidase like 3 involved_in ISO (PMID:25384971)
(MGI:5640905|PMID:25384971)
UniProt PMID:25384971 MGI:5640905 NCBI chr12:118,351,199...118,489,579
Ensembl chr12:121,723,881...121,773,429
JBrowse link
G STK11 serine/threonine kinase 11 acts_upstream_of_or_within ISO (MGI:5003385|PMID:21487392) MGI PMID:21487392 MGI:5003385 Ensembl chr19:1,188,537...1,210,677 JBrowse link
G STOML2 stomatin like 2 involved_in ISO (PMID:18641330) UniProt PMID:18641330 NCBI chr 9:34,950,387...34,953,707
Ensembl chr 9:35,755,790...35,759,091
JBrowse link
G THEMIS thymocyte selection associated involved_in ISO (MGI:4352756|PMID:19597499), (MGI:4352757|PMID:19597498) UniProt PMID:19597498 PMID:19597499 MGI:4352756 MGI:4352757 NCBI chr 6:125,489,491...125,685,995
Ensembl chr 6:129,601,176...129,797,112
JBrowse link
G THEMIS2 thymocyte selection associated family member 2 acts_upstream_of_or_within ISO (MGI:5446993|PMID:22732588) MGI PMID:22732588 MGI:5446993 NCBI chr 1:27,131,378...27,146,971
Ensembl chr 1:28,171,799...28,186,915
JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISO PMID:9285719 UniProt PMID:9285719 RGD:8554466 NCBI chr11:114,253,535...114,259,495
Ensembl chr11:118,180,717...118,186,901
JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in ISO (MGI:2137821|PMID:11485735) UniProt PMID:11485735 MGI:2137821 NCBI chr 6:46,815,762...46,894,286
Ensembl chr 6:48,079,749...48,158,356
JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr11:36,457,633...36,483,616
Ensembl chr11:36,335,609...36,356,334
JBrowse link
G TXK TXK tyrosine kinase involved_in ISO (MGI:1335923|PMID:10213685) UniProt PMID:10213685 MGI:1335923 NCBI chr 4:74,039,292...74,086,744
Ensembl chr 4:84,750,804...84,818,671
JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr12:90,951,446...90,984,075 JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in ISO (MGI:6141968|PMID:27400149) BHF-UCL PMID:27400149 MGI:6141968 NCBI chr12:825,659...985,016
Ensembl chr12:791,153...944,602
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in ISO (MGI:6142401|PMID:25282160)
(MGI:5706909|PMID:23185455)
UniProt PMID:23185455 PMID:25282160 MGI:5706909 MGI:6142401 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
G ZNF683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chr 1:25,622,548...25,636,106
Ensembl chr 1:26,690,359...26,703,755
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12661
    immune system process 2095
      activation of immune response 234
        activation of innate immune response + 34
        complement activation + 34
        immune response-activating signal transduction + 174
Path 2
Term Annotations click to browse term
  biological_process 12661
    biological regulation 9216
      regulation of biological process 8710
        positive regulation of biological process 5666
          positive regulation of response to stimulus 1957
            positive regulation of immune response 437
              activation of immune response 234
                activation of innate immune response + 34
                complement activation + 34
                immune response-activating signal transduction + 174
paths to the root