Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:somatic diversification of immune receptors
go back to main search page
Accession:GO:0002200 term browser browse the term
Definition:The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.
Comment:Note that this process covers somatic recombination, gene conversion, hypermutation, N-region addition, and alternate splicing processes of immune receptor diversification.


GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24388753) Ensembl
MGI
PMID:24388753 GO_REF:0000107 NCBI chrNW_004936785:324,655...350,496
Ensembl chrNW_004936785:323,941...350,539
JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (PMID:23531880) MGI PMID:23531880 NCBI chrNW_004936604:3,911,407...3,945,405 JBrowse link
immunoglobulin V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyren cell cycle regulator of NHEJ involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936579:768,153...776,053
Ensembl chrNW_004936579:768,252...770,440
JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
JBrowse link
G Lig4 DNA ligase 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9823897) Ensembl
MGI
TreeGrafter
PMID:9823897 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936472:3,861,833...3,867,943
Ensembl chrNW_004936472:3,861,866...3,867,933
JBrowse link
G Nhej1 non-homologous end joining factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936569:1,494,783...1,578,587
Ensembl chrNW_004936569:1,495,446...1,578,590
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9768755) Ensembl
MGI
TreeGrafter
PMID:9768755 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936590:4,722,914...4,887,615
Ensembl chrNW_004936590:4,722,873...4,890,156
JBrowse link
G Tcf3 transcription factor 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16428437) MGI
TreeGrafter
Ensembl
PMID:16428437 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936588:884,817...913,052
Ensembl chrNW_004936588:884,789...912,753
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9875844) TreeGrafter
MGI
PMID:9875844 GO_REF:0000118 NCBI chrNW_004936469:2,248,367...2,495,215
Ensembl chrNW_004936469:2,248,039...2,495,226
JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17713479) Ensembl
MGI
PMID:17713479 GO_REF:0000107 NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601
JBrowse link
G Atad5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of
IEA
ISO
(PMID:25404367) Ensembl
MGI
PMID:25404367 GO_REF:0000107 NCBI chrNW_004936538:2,815,370...2,877,084
Ensembl chrNW_004936538:2,811,174...2,874,113
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:4,607,716...4,631,237
Ensembl chrNW_004936488:4,607,716...4,631,283
JBrowse link
G Cd40lg CD40 ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936513:10,607,617...10,620,403
Ensembl chrNW_004936513:10,607,617...10,620,403
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15280420) Ensembl
MGI
PMID:15280420 GO_REF:0000107 NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745
JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004936526:8,570,488...8,627,004 JBrowse link
G Exosc3 exosome component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:5,580,855...5,586,170
Ensembl chrNW_004936524:5,581,090...5,586,128
JBrowse link
G Exosc6 exosome component 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:23,295,441...23,297,321
Ensembl chrNW_004936475:23,295,500...23,296,318
JBrowse link
G Lig4 DNA ligase 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17713479) Ensembl
MGI
PMID:17713479 GO_REF:0000107 NCBI chrNW_004936472:3,861,833...3,867,943
Ensembl chrNW_004936472:3,861,866...3,867,933
JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12743174) Ensembl
MGI
PMID:12743174 GO_REF:0000107 NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12743174)
(PMID:10430621)
Ensembl
MGI
PMID:10430621 PMID:12743174 GO_REF:0000107 NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
JBrowse link
G Msh6 mutS homolog 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16618598)
(PMID:17015724)
Ensembl
MGI
PMID:16618598 PMID:17015724 GO_REF:0000107 NCBI chrNW_004936508:4,708,661...4,728,671
Ensembl chrNW_004936508:4,708,661...4,728,787
JBrowse link
G Nbn nibrin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936544:3,773,828...3,812,673
Ensembl chrNW_004936544:3,775,220...3,808,837
JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936630:1,601,006...1,633,844
Ensembl chrNW_004936630:1,601,010...1,632,745
JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chrNW_004936784:1,073,236...1,094,575 JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chrNW_004936476:22,074,146...22,121,286 JBrowse link
G Sanbr SANT and BTB domain regulator of CSR involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936491:6,578,538...6,629,610
Ensembl chrNW_004936491:6,578,484...6,630,513
JBrowse link
G Swap70 switching B cell complex subunit SWAP70 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9642267) Ensembl
MGI
PMID:9642267 GO_REF:0000107 NCBI chrNW_004936528:8,441,839...8,511,374
Ensembl chrNW_004936528:8,441,527...8,511,376
JBrowse link
G Ung uracil DNA glycosylase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17015724) Ensembl
MGI
PMID:17015724 GO_REF:0000107 NCBI chrNW_004936769:911,296...922,770
Ensembl chrNW_004936769:910,838...922,726
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004936469:2,248,367...2,495,215
Ensembl chrNW_004936469:2,248,039...2,495,226
JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:16,669,297...16,689,451
Ensembl chrNW_004936489:16,669,297...16,689,451
JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor involved_in
acts_upstream_of
IEA
ISO
(PMID:10490661) Ensembl
MGI
PMID:10490661 GO_REF:0000107 NCBI chrNW_004936578:2,371,976...2,395,034
Ensembl chrNW_004936578:2,371,945...2,395,071
JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of
IEA
ISO
(PMID:16275384) Ensembl
MGI
PMID:16275384 GO_REF:0000107 NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308
JBrowse link
G Stat6 signal transducer and activator of transcription 6 involved_in
acts_upstream_of
IEA
ISO
(PMID:10490661) Ensembl
MGI
PMID:10490661 GO_REF:0000107 NCBI chrNW_004936646:1,297,530...1,312,508
Ensembl chrNW_004936646:1,296,290...1,312,157
JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chrNW_004936506:1,678,069...1,687,632 JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly(ADP-ribose) polymerase family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:3,291,282...3,297,581
Ensembl chrNW_004936529:3,291,269...3,299,992
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10490661) Ensembl
MGI
PMID:10490661 GO_REF:0000107 NCBI chrNW_004936578:2,371,976...2,395,034
Ensembl chrNW_004936578:2,371,945...2,395,071
JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16275384) Ensembl
MGI
PMID:16275384 GO_REF:0000107 NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004936504:12,053,470...12,103,346 JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21255825) Ensembl
MGI
PMID:21255825 GO_REF:0000107 NCBI chrNW_004936524:5,580,855...5,586,170
Ensembl chrNW_004936524:5,581,090...5,586,128
JBrowse link
G Exosc6 exosome component 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21255825) Ensembl
MGI
PMID:21255825 GO_REF:0000107 NCBI chrNW_004936475:23,295,441...23,297,321
Ensembl chrNW_004936475:23,295,500...23,296,318
JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936798:261,566...284,480
Ensembl chrNW_004936798:261,661...273,011
JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:1,928,172...1,983,983
Ensembl chrNW_004936599:1,928,145...1,984,008
JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936886:596,949...602,959
Ensembl chrNW_004936886:595,782...604,286
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:538,703...542,901
Ensembl chrNW_004936474:538,625...542,901
JBrowse link
G Paxip1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:9,440,129...9,488,215
Ensembl chrNW_004936527:9,440,036...9,484,245
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:26,045,500...26,105,980
Ensembl chrNW_004936469:26,048,953...26,105,997
JBrowse link
G Shld1 shieldin complex subunit 1 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936485:13,179,218...13,267,980
Ensembl chrNW_004936485:13,176,426...13,267,953
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:5,315,297...5,400,752
Ensembl chrNW_004936601:5,315,261...5,396,301
JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893
G Tfrc transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936784:696,738...728,385
Ensembl chrNW_004936784:696,713...728,543
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:6,589,395...6,668,242
Ensembl chrNW_004936471:6,589,564...6,668,305
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101977665 tumor necrosis factor ligand superfamily member 12 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936595:831,252...839,783
Ensembl chrNW_004936595:830,466...839,748
JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23241889) Ensembl
MGI
PMID:23241889 GO_REF:0000107 NCBI chrNW_004936477:21,460,442...21,531,563
Ensembl chrNW_004936477:21,460,478...21,534,909
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004936750:439,396...468,747 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
ISS
(PMID:14988498) MGI
Ensembl
AgBase
PMID:14988498 GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272
JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:14988498) MGI
TreeGrafter
Ensembl
PMID:14988498 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936595:839,877...842,962
Ensembl chrNW_004936595:839,877...842,962
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin like cytokine factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:2,372,889...2,376,316
Ensembl chrNW_004936599:2,372,031...2,376,939
JBrowse link
G Stat6 signal transducer and activator of transcription 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10490661) Ensembl
MGI
PMID:10490661 GO_REF:0000107 NCBI chrNW_004936646:1,297,530...1,312,508
Ensembl chrNW_004936646:1,296,290...1,312,157
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25404367) Ensembl
MGI
PMID:25404367 GO_REF:0000107 NCBI chrNW_004936538:2,815,370...2,877,084
Ensembl chrNW_004936538:2,811,174...2,874,113
JBrowse link
G Cd28 CD28 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:7688139) Ensembl
MGI
PMID:7688139 GO_REF:0000107 NCBI chrNW_004936631:335,411...363,407
Ensembl chrNW_004936631:335,411...363,407
JBrowse link
G Cd40 CD40 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12882831) Ensembl
MGI
TreeGrafter
PMID:12882831 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
JBrowse link
G Il2 interleukin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:1830926) Ensembl
MGI
PMID:1830926 GO_REF:0000107 NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625
JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004936501:12,657,092...12,660,106
Ensembl chrNW_004936501:12,656,435...12,660,067
JBrowse link
G Paxip1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:9,440,129...9,488,215
Ensembl chrNW_004936527:9,440,036...9,484,245
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004936750:439,396...468,747 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9015183) Ensembl
MGI
PMID:9015183 GO_REF:0000107 NCBI chrNW_004936567:5,266,653...5,378,464
Ensembl chrNW_004936567:5,267,615...5,378,258
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12882831) Ensembl
MGI
PMID:12882831 GO_REF:0000107 NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635
JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21211721) Ensembl
MGI
PMID:21211721 GO_REF:0000107 NCBI chrNW_004936491:12,857,928...12,961,709
Ensembl chrNW_004936491:12,857,785...12,962,376
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:4,878,645...4,910,613
Ensembl chrNW_004936538:4,878,662...4,910,597
JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16275384) Ensembl
MGI
PMID:16275384 GO_REF:0000107 NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11057672) Ensembl
MGI
PMID:11057672 GO_REF:0000107 NCBI chrNW_004936659:2,706,037...2,720,486
Ensembl chrNW_004936659:2,705,985...2,722,748
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004936504:12,053,470...12,103,346 JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:5649169|PMID:25310967) UniProt PMID:25310967 MGI:5649169 NCBI chrNW_004936660:481,772...493,567 JBrowse link
somatic diversification of immune receptors via somatic mutation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase RNA specific involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23209284) Ensembl
MGI
PMID:23209284 GO_REF:0000107 NCBI chrNW_004936580:4,183,016...4,208,341
Ensembl chrNW_004936580:4,183,079...4,203,435
JBrowse link
somatic diversification of immunoglobulins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601
JBrowse link
G Ctnnbl1 catenin beta like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936561:3,434,232...3,589,341
Ensembl chrNW_004936561:3,434,731...3,589,341
JBrowse link
G Polb DNA polymerase beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24388753) Ensembl
MGI
PMID:24388753 GO_REF:0000107 NCBI chrNW_004936785:324,655...350,496
Ensembl chrNW_004936785:323,941...350,539
JBrowse link
somatic hypermutation of immunoglobulin genes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601
JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004936526:8,570,488...8,627,004 JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936798:261,566...284,480
Ensembl chrNW_004936798:261,661...273,011
JBrowse link
G Mcm3ap minichromosome maintenance complex component 3 associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936778:273,152...318,157
Ensembl chrNW_004936778:273,909...319,232
JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10092760), (PMID:10429667) Ensembl
MGI
TreeGrafter
PMID:10092760 PMID:10429667 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
NOT|acts_upstream_of_or_within
IEA
ISO
(PMID:14568978)
(PMID:15494304)
(PMID:9607915)
(PMID:9607916)
(PMID:9697842), (PMID:9697843)
Ensembl
MGI
PMID:9607915 PMID:9607916 PMID:9697842 PMID:9697843 PMID:14568978 More... GO_REF:0000107 NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
JBrowse link
G Msh3 mutS homolog 3 NOT|acts_upstream_of_or_within ISO (PMID:10662804) MGI PMID:10662804 NCBI chrNW_004936469:82,967...275,772
Ensembl chrNW_004936469:83,285...273,561
JBrowse link
G Msh6 mutS homolog 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10662804), (PMID:15238604), (PMID:17015724)
(PMID:16618598)
Ensembl
MGI
PMID:10662804 PMID:15238604 PMID:16618598 PMID:17015724 GO_REF:0000107 NCBI chrNW_004936508:4,708,661...4,728,671
Ensembl chrNW_004936508:4,708,661...4,728,787
JBrowse link
G Nuggc nuclear GTPase, germinal center associated acts_upstream_of_or_within ISO (PMID:22833677) MGI PMID:22833677 NCBI chrNW_004936675:885,015...931,657
Ensembl chrNW_004936675:885,039...920,253
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10429667) TreeGrafter
MGI
PMID:10429667 GO_REF:0000118 NCBI chrNW_004936750:439,396...468,747 JBrowse link
G Polb DNA polymerase beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24388753) Ensembl
MGI
PMID:24388753 GO_REF:0000107 NCBI chrNW_004936785:324,655...350,496
Ensembl chrNW_004936785:323,941...350,539
JBrowse link
G Polm DNA polymerase mu acts_upstream_of_or_within ISO (PMID:15789338) MGI PMID:15789338 NCBI chrNW_004936478:19,032,995...19,042,400
Ensembl chrNW_004936478:19,032,920...19,042,432
JBrowse link
G Polq DNA polymerase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936536:7,904,166...8,004,305
Ensembl chrNW_004936536:7,904,981...8,004,199
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936561:4,180,607...4,238,623
Ensembl chrNW_004936561:4,180,546...4,229,036
JBrowse link
G Ung uracil DNA glycosylase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17015724)
(PMID:15494304)
Ensembl
MGI
PMID:15494304 PMID:17015724 GO_REF:0000107 NCBI chrNW_004936769:911,296...922,770
Ensembl chrNW_004936769:910,838...922,726
JBrowse link
somatic recombination of immunoglobulin gene segments term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11828012) Ensembl
MGI
PMID:11828012 GO_REF:0000107 NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11828012)
(PMID:14563316), (PMID:15955838)
(PMID:15494304)
(PMID:14568978)
Ensembl
MGI
PMID:11828012 PMID:14563316 PMID:14568978 PMID:15494304 PMID:15955838 GO_REF:0000107 NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
JBrowse link
G Msh3 mutS homolog 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15238604) TreeGrafter
MGI
PMID:15238604 GO_REF:0000118 NCBI chrNW_004936469:82,967...275,772
Ensembl chrNW_004936469:83,285...273,561
JBrowse link
G Msh6 mutS homolog 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15238604) Ensembl
MGI
PMID:15238604 GO_REF:0000107 NCBI chrNW_004936508:4,708,661...4,728,671
Ensembl chrNW_004936508:4,708,661...4,728,787
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component acts_upstream_of_or_within ISO (PMID:11828012) MGI PMID:11828012 NCBI chrNW_004936750:439,396...468,747 JBrowse link
G Ung uracil DNA glycosylase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15494304) Ensembl
MGI
PMID:15494304 GO_REF:0000107 NCBI chrNW_004936769:911,296...922,770
Ensembl chrNW_004936769:910,838...922,726
JBrowse link
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12743174) Ensembl
MGI
PMID:12743174 GO_REF:0000107 NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12743174) Ensembl
MGI
TreeGrafter
PMID:12743174 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
JBrowse link
T cell receptor V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl11b BCL11 transcription factor B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12717433) Ensembl
MGI
PMID:12717433 GO_REF:0000107 NCBI chrNW_004936604:3,023,781...3,110,104
Ensembl chrNW_004936604:3,023,844...3,110,083
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9462507) Ensembl
MGI
PMID:9462507 GO_REF:0000107 NCBI chrNW_004936818:453,635...569,194
Ensembl chrNW_004936818:453,635...567,469
JBrowse link
G Lig4 DNA ligase 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10911993) Ensembl
MGI
PMID:10911993 GO_REF:0000107 NCBI chrNW_004936472:3,861,833...3,867,943
Ensembl chrNW_004936472:3,861,866...3,867,933
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9768755) Ensembl
MGI
PMID:9768755 GO_REF:0000107 NCBI chrNW_004936590:4,722,914...4,887,615
Ensembl chrNW_004936590:4,722,873...4,890,156
JBrowse link
G Tcf7 transcription factor 7 acts_upstream_of_or_within ISO (PMID:9462507) MGI PMID:9462507 NCBI chrNW_004936647:1,096,726...1,125,753
Ensembl chrNW_004936647:1,097,019...1,125,729
JBrowse link
V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23836881) Ensembl
MGI
PMID:23836881 GO_REF:0000107 NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211
JBrowse link
G Dcaf1 DDB1 and CUL4 associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:2,786,252...2,856,516
Ensembl chrNW_004936529:2,786,252...2,856,967
JBrowse link
G Dclre1c DNA cross-link repair 1C involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23836881) Ensembl
MGI
PMID:23836881 GO_REF:0000107 NCBI chrNW_004936613:1,467,797...1,501,107
Ensembl chrNW_004936613:1,470,365...1,501,138
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:9166431) UniProt PMID:9166431 NCBI chrNW_004936472:25,236,728...25,246,585
Ensembl chrNW_004936472:25,236,728...25,246,580
JBrowse link
G Lig1 DNA ligase 1 NOT|involved_in ISO (PMID:9809069) UniProt PMID:9809069 NCBI chrNW_004936664:2,242,916...2,276,286
Ensembl chrNW_004936664:2,242,897...2,276,715
JBrowse link
G Lig3 DNA ligase 3 NOT|involved_in ISO (PMID:9809069) UniProt PMID:9809069 NCBI chrNW_004936538:206,179...228,487
Ensembl chrNW_004936538:206,839...226,441
JBrowse link
G Lig4 DNA ligase 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10716994)
(PMID:15194694)
Ensembl
MGI
PMID:10716994 PMID:15194694 GO_REF:0000107 NCBI chrNW_004936472:3,861,833...3,867,943
Ensembl chrNW_004936472:3,861,866...3,867,933
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23836881) Ensembl
MGI
PMID:23836881 GO_REF:0000107 NCBI chrNW_004936590:4,722,914...4,887,615
Ensembl chrNW_004936590:4,722,873...4,890,156
JBrowse link
G Rag1 recombination activating 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:2360047) InterPro
MGI
TreeGrafter
Ensembl
UniProt
PMID:2360047 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936533:1,817,135...1,827,393
Ensembl chrNW_004936533:1,817,135...1,827,393
JBrowse link
G Rag2 recombination activating 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:2360047) Ensembl
MGI
TreeGrafter
PMID:2360047 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936533:1,801,207...1,807,431
Ensembl chrNW_004936533:1,801,391...1,807,431
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:10716994) MGI PMID:10716994 NCBI chrNW_004936469:2,248,367...2,495,215
Ensembl chrNW_004936469:2,248,039...2,495,226
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 acts_upstream_of_or_within ISO (PMID:10716994) MGI PMID:10716994 NCBI chrNW_004936492:303,843...325,812
Ensembl chrNW_004936492:300,057...325,845
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    immune system process 2209
      somatic diversification of immune receptors 83
        somatic diversification of DSCAM-based immune receptors 0
        somatic diversification of FREP-based immune receptors 0
        somatic diversification of T cell receptor genes + 5
        somatic diversification of immune receptors by N region addition + 0
        somatic diversification of immune receptors via alternate splicing + 0
        somatic diversification of immune receptors via gene conversion + 0
        somatic diversification of immune receptors via germline recombination within a single locus + 76
        somatic diversification of immune receptors via somatic mutation + 16
        somatic diversification of immunoglobulins + 70
        somatic diversification of variable lymphocyte receptors of jawless fish 0
Path 2
Term Annotations click to browse term
  biological_process 15969
    developmental process 6329
      anatomical structure development 5961
        multicellular organism development 4836
          system development 4211
            immune system development 226
              somatic diversification of immune receptors 83
                somatic diversification of DSCAM-based immune receptors 0
                somatic diversification of FREP-based immune receptors 0
                somatic diversification of T cell receptor genes + 5
                somatic diversification of immune receptors by N region addition + 0
                somatic diversification of immune receptors via alternate splicing + 0
                somatic diversification of immune receptors via gene conversion + 0
                somatic diversification of immune receptors via germline recombination within a single locus + 76
                somatic diversification of immune receptors via somatic mutation + 16
                somatic diversification of immunoglobulins + 70
                somatic diversification of variable lymphocyte receptors of jawless fish 0
paths to the root