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Term:MAML1-RBP-Jkappa- ICN1 complex
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Accession:GO:0002193 term browser browse the term
Definition:A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
Synonyms:exact_synonym: MAML1-CSL-ICN1;   MAML1-CSL-Notch1 complex;   MAML1-RBP-Jkappa-Notch1 complex

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MAML1-RBP-Jkappa- ICN1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Maml1 mastermind-like transcriptional coactivator 1 part_of ISO (PMID:16510869) RGD PMID:16510869 NCBI chr10:34,588,639...34,624,298
Ensembl chr10:34,588,646...34,623,338
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G Notch1 notch receptor 1 part_of ISO (PMID:16510869) RGD PMID:16510869 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G Rbpj recombination signal binding protein for immunoglobulin kappa J region part_of IBA
RGD PMID:16510869 PMID:21873635 RGD:13792537 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
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G Rbpjl2 recombination signal binding protein for immunoglobulin kappa J region-like 2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:5,464,652...5,466,381
Ensembl chr 5:5,464,397...5,466,366
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  cellular_component 20072
    protein-containing complex 6252
      MAML1-RBP-Jkappa- ICN1 complex 4
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