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ONTOLOGY REPORT - ANNOTATIONS

Term:3-methylcrotonyl-CoA carboxylase complex, mitochondrial
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Accession:GO:0002169 term browser browse the term
Definition:A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.
Synonyms:exact_synonym: mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme;   mitochondrial MCCC complex;   mitochondrial methylcrotonoyl-CoA carboxylase complex


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3-methylcrotonyl-CoA carboxylase complex, mitochondrial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 located_in ISO (PMID:17360195) RGD PMID:17360195 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222 		JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 located_in ISO (PMID:17360195) RGD PMID:17360195 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20075
    protein-containing complex 6253
      mitochondrial protein-containing complex 355
        3-methylcrotonyl-CoA carboxylase complex, mitochondrial 2
Path 2
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  cellular_component 20075
    cellular anatomical entity 19914
      intracellular anatomical structure 14408
        intracellular organelle 12811
          intracellular membrane-bounded organelle 11202
            mitochondrion 1726
              mitochondrial protein-containing complex 355
                3-methylcrotonyl-CoA carboxylase complex, mitochondrial 2
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