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ONTOLOGY REPORT - ANNOTATIONS

Term:3-methylcrotonyl-CoA carboxylase complex, mitochondrial
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Accession:GO:0002169 term browser browse the term
Definition:A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.
Synonyms:exact_synonym: mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme;   mitochondrial MCCC complex;   mitochondrial methylcrotonoyl-CoA carboxylase complex


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3-methylcrotonyl-CoA carboxylase complex, mitochondrial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCCC1 methylcrotonyl-CoA carboxylase subunit 1 located_in
part_of		 ISO
IEA		 (PMID:17360195) ComplexPortal
Ensembl		 PMID:17360195 GO_REF:0000107 NCBI chr34:16,022,493...16,084,346
Ensembl chr34:16,022,499...16,084,387 		JBrowse link
G MCCC2 methylcrotonyl-CoA carboxylase subunit 2 located_in ISO (PMID:17360195) ComplexPortal PMID:17360195 NCBI chr 2:54,751,703...54,825,133
Ensembl chr 2:54,751,698...54,823,273 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18903
    protein-containing complex 6509
      mitochondrial protein-containing complex 325
        3-methylcrotonyl-CoA carboxylase complex, mitochondrial 2
Path 2
Term Annotations click to browse term
  cellular_component 18903
    cellular anatomical entity 18651
      intracellular anatomical structure 14364
        intracellular organelle 12807
          intracellular membrane-bounded organelle 11482
            mitochondrion 1756
              mitochondrial protein-containing complex 325
                3-methylcrotonyl-CoA carboxylase complex, mitochondrial 2
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