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ONTOLOGY REPORT - ANNOTATIONS


Term:thyroid hormone mediated signaling pathway
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Accession:GO:0002154 term browser browse the term
Definition:A series of molecular signals mediated by the detection of a thyroid hormone.
Synonyms:exact_synonym: thyroid hormone mediated signalling pathway


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thyroid hormone mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Med1 mediator complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:14,625,201...14,663,184 JBrowse link
positive regulation of thyroid hormone mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:2,735,111...2,763,060 JBrowse link
G Thra thyroid hormone receptor alpha involved_in ISO (PMID:1310350)
(MGI:6827315|PMID:8910441)
ComplexPortal PMID:1310350 PMID:8910441 MGI:6827315 NCBI chrNW_004936490:15,188,341...15,206,032 JBrowse link
G Thrb thyroid hormone receptor beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:15,766,214...15,986,389 JBrowse link
regulation of thyroid hormone mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphb5 glycoprotein hormone subunit beta 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4453244|PMID:20223276) MGI
Ensembl
PMID:20223276 GO_REF:0000107 MGI:4453244 NCBI chrNW_004936495:7,186,985...7,192,745 JBrowse link
G LOC101970240 prolylcarboxypeptidase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5313762|PMID:22202165) MGI
Ensembl
PMID:22202165 GO_REF:0000107 MGI:5313762 NCBI chrNW_004936498:11,037,294...11,109,657 JBrowse link
G Ncoa1 nuclear receptor coactivator 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5585573|PMID:24550004) MGI
Ensembl
PMID:24550004 GO_REF:0000107 MGI:5585573 NCBI chrNW_004936493:7,368,393...7,605,754 JBrowse link
G Ncor1 nuclear receptor corepressor 1 acts_upstream_of_or_within ISO (MGI:5585573|PMID:24550004) MGI PMID:24550004 MGI:5585573 NCBI chrNW_004936821:382,756...538,254 JBrowse link
G Thra thyroid hormone receptor alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2677074|PMID:12869545) MGI
Ensembl
PMID:12869545 GO_REF:0000107 MGI:2677074 NCBI chrNW_004936490:15,188,341...15,206,032 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14954
    cellular process 14088
      signal transduction 5224
        intracellular receptor signaling pathway 231
          thyroid hormone mediated signaling pathway 8
            negative regulation of thyroid hormone mediated signaling pathway 0
            positive regulation of thyroid hormone mediated signaling pathway 3
            regulation of thyroid hormone mediated signaling pathway + 7
Path 2
Term Annotations click to browse term
  biological_process 14954
    response to stimulus 7960
      cellular response to stimulus 6670
        cellular response to chemical stimulus 2951
          cellular response to organic substance 2395
            cellular response to hormone stimulus 661
              hormone-mediated signaling pathway 159
                thyroid hormone mediated signaling pathway 8
                  negative regulation of thyroid hormone mediated signaling pathway 0
                  positive regulation of thyroid hormone mediated signaling pathway 3
                  regulation of thyroid hormone mediated signaling pathway + 7
paths to the root