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ONTOLOGY REPORT - ANNOTATIONS

Term:retinoic acid biosynthetic process
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Accession:GO:0002138 term browser browse the term
Definition:The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.
Synonyms:exact_synonym: retinoic acid anabolic process;   retinoic acid biosynthesis


show annotations for term's descendants           Sort by:
retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 3110069K09Rik RIKEN cDNA 3110069K09 gene acts_upstream_of_or_within IMP (PMID:17473173) MGI PMID:17473173 NCBI chr 1:16,176,106...16,202,774
Ensembl chr 1:16,175,998...16,203,958 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 involved_in ISO RGD
MGI		 PMID:21138835 GO_REF:0000096 MGI:4417868 RGD:6771354 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 involved_in ISO RGD
MGI		 PMID:15950969 PMID:21138835 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:6771322 RGD:6771354 NCBI chr 9:71,123,071...71,203,525
Ensembl chr 9:71,123,071...71,203,525 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 involved_in
acts_upstream_of_or_within		 IMP
IDA
ISO		 (MGI:3042765|PMID:14623956)
(PMID:11013254), (PMID:11044606), (PMID:16241904)		 UniProt
MGI
RGD		 PMID:11013254 PMID:11044606 PMID:14623956 PMID:15950969 PMID:16241904 More... GO_REF:0000096 GO_REF:0000119 MGI:3042765 MGI:4417868 MGI:4834177 RGD:6771322 RGD:6771354 NCBI chr 7:66,040,640...66,077,225
Ensembl chr 7:66,040,638...66,077,265 		JBrowse link
G Crabp2 cellular retinoic acid binding protein II ISO RGD PMID:15950969 RGD:6771322 NCBI chr 3:87,856,000...87,860,679
Ensembl chr 3:87,855,973...87,860,683 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO RGD
MGI		 PMID:15950969 PMID:21138835 GO_REF:0000096 MGI:4417868 RGD:6771322 RGD:6771354 NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877 		JBrowse link
G Rbp1 retinol binding protein 1, cellular involved_in IEA
ISO		 UniProt
RGD		 PMID:15950969 GO_REF:0000002 MGI:2152098 RGD:6771322 NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628 		JBrowse link
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 acts_upstream_of_or_within IDA (PMID:11876656) MGI PMID:11876656 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 acts_upstream_of_or_within IDA (PMID:11876656) MGI PMID:11876656 NCBI chr 9:71,123,071...71,203,525
Ensembl chr 9:71,123,071...71,203,525 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 acts_upstream_of_or_within IDA (PMID:11876656) MGI PMID:11876656 NCBI chr10:21,253,199...21,272,477
Ensembl chr10:21,253,190...21,272,484 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 involved_in ISO 9-cis- and all-trans-retinoic acid synthesized from 9-cis- and all-trans-retinal RGD
MGI		 PMID:8765131 GO_REF:0000096 MGI:4417868 RGD:2306683 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877 		JBrowse link
G Rdh16 retinol dehydrogenase 16 acts_upstream_of_or_within IDA (PMID:11876656) MGI PMID:11876656 NCBI chr10:127,636,959...127,651,715
Ensembl chr10:127,637,021...127,682,434 		JBrowse link
G Rdh9 retinol dehydrogenase 9 acts_upstream_of_or_within IDA (PMID:11876656) MGI PMID:11876656 NCBI chr10:127,612,274...127,628,566
Ensembl chr10:127,612,255...127,628,566 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c14 aldo-keto reductase family 1, member C14 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,099,015...4,140,569
Ensembl chr13:4,099,011...4,140,688 		JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653 		JBrowse link
G Akr1c20 aldo-keto reductase family 1, member C20 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344 		JBrowse link
G Akr1c6 aldo-keto reductase family 1, member C6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876 		JBrowse link
G Akr1cl aldo-keto reductase family 1, member C-like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:65,052,237...65,071,918
Ensembl chr 1:65,051,848...65,071,918 		JBrowse link
G Prmt3 protein arginine N-methyltransferase 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:49,428,067...49,508,016
Ensembl chr 7:49,428,094...49,508,013 		JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 3110069K09Rik RIKEN cDNA 3110069K09 gene involved_in ISO RGD
MGI		 PMID:21138835 GO_REF:0000096 MGI:4417868 RGD:6771354 NCBI chr 1:16,176,106...16,202,774
Ensembl chr 1:16,175,998...16,203,958 		JBrowse link
G Rdh1 retinol dehydrogenase 1 (all trans) involved_in ISO MGI
RGD		 PMID:21138835 GO_REF:0000096 MGI:4417868 RGD:6771354 NCBI chr10:127,595,595...127,604,168
Ensembl chr10:127,595,590...127,604,166 		JBrowse link
G Rdh16 retinol dehydrogenase 16 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr10:127,636,959...127,651,715
Ensembl chr10:127,637,021...127,682,434 		JBrowse link
G Rdh16f2 RDH16 family member 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr10:127,702,345...127,713,188
Ensembl chr10:127,702,343...127,713,186 		JBrowse link
G Rdh19 retinol dehydrogenase 19 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr10:127,685,797...127,697,045
Ensembl chr10:127,685,797...127,697,045 		JBrowse link
G Rdh9 retinol dehydrogenase 9 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr10:127,612,274...127,628,566
Ensembl chr10:127,612,255...127,628,566 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28702
    metabolic process 11703
      hormone metabolic process 260
        retinoic acid metabolic process 41
          retinoic acid biosynthetic process 20
            9-cis-retinoic acid biosynthetic process 7
            negative regulation of retinoic acid biosynthetic process 6
            positive regulation of retinoic acid biosynthetic process 6
            regulation of retinoic acid biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 28702
    metabolic process 11703
      primary metabolic process 10354
        lipid metabolic process 1503
          cellular lipid metabolic process 1091
            isoprenoid metabolic process 119
              terpenoid metabolic process 95
                diterpenoid metabolic process 85
                  retinoid metabolic process 76
                    retinoic acid metabolic process 41
                      retinoic acid biosynthetic process 20
                        9-cis-retinoic acid biosynthetic process 7
                        negative regulation of retinoic acid biosynthetic process 6
                        positive regulation of retinoic acid biosynthetic process 6
                        regulation of retinoic acid biosynthetic process + 12
paths to the root