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ONTOLOGY REPORT - ANNOTATIONS

Term:retinoic acid biosynthetic process
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Accession:GO:0002138 term browser browse the term
Definition:The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.
Synonyms:exact_synonym: retinoic acid anabolic process;   retinoic acid biosynthesis

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retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 involved_in ISO (PMID:33565183)
(PMID:29240402)		 RGD
UniProt		 PMID:15950969 PMID:21138835 PMID:29240402 PMID:33565183 RGD:6771322 RGD:6771354 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 acts_upstream_of_or_within
involved_in		 ISO (PMID:11013254), (PMID:11044606), (PMID:16241904)
(MGI:3042765|PMID:14623956)
(PMID:27759097)		 RGD
MGI
UniProt		 PMID:11013254 PMID:11044606 PMID:14623956 PMID:15950969 PMID:16241904 More... MGI:3042765 RGD:6771322 RGD:6771354 NCBI chrNW_004955416:27,823,611...27,858,112
Ensembl chrNW_004955416:27,823,611...27,858,173 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 ISO RGD PMID:15950969 RGD:6771322 NCBI chrNW_004955545:2,777,523...2,782,567
Ensembl chrNW_004955545:2,777,474...2,782,567 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 ISO RGD PMID:15950969 PMID:21138835 RGD:6771322 RGD:6771354 NCBI chrNW_004955449:5,360,486...5,380,279
Ensembl chrNW_004955449:5,359,617...5,380,267 		JBrowse link
G Rbp1 retinol binding protein 1 ISO RGD PMID:15950969 RGD:6771322 NCBI chrNW_004955508:6,046,738...6,072,202
Ensembl chrNW_004955508:6,046,316...6,072,288 		JBrowse link
G Rdh10 retinol dehydrogenase 10 acts_upstream_of_or_within ISO (PMID:17473173) MGI PMID:17473173 NCBI chrNW_004955444:6,878,722...6,909,421
Ensembl chrNW_004955444:6,878,722...6,909,421 		JBrowse link
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 acts_upstream_of_or_within ISO (PMID:11876656) MGI PMID:11876656 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family member A1 acts_upstream_of_or_within ISO (PMID:11876656) MGI PMID:11876656 NCBI chrNW_004955439:1,773,884...1,794,325
Ensembl chrNW_004955439:1,773,861...1,794,328 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO (PMID:11304534) UniProt PMID:11304534 NCBI chrNW_004955449:5,360,486...5,380,279
Ensembl chrNW_004955449:5,359,617...5,380,267 		JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO 9-cis- and all-trans-retinoic acid synthesized from 9-cis- and all-trans-retinal RGD PMID:8765131 RGD:2306683 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt3 protein arginine methyltransferase 3 involved_in ISO (PMID:33495566) UniProt PMID:33495566 NCBI chrNW_004955476:1,222,579...1,331,582
Ensembl chrNW_004955476:1,223,076...1,331,582 		JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rdh10 retinol dehydrogenase 10 ISO RGD PMID:21138835 RGD:6771354 NCBI chrNW_004955444:6,878,722...6,909,421
Ensembl chrNW_004955444:6,878,722...6,909,421 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12483
    metabolic process 7924
      hormone metabolic process 174
        retinoic acid metabolic process 15
          retinoic acid biosynthetic process 9
            9-cis-retinoic acid biosynthetic process 4
            negative regulation of retinoic acid biosynthetic process 1
            positive regulation of retinoic acid biosynthetic process 1
            regulation of retinoic acid biosynthetic process + 2
Path 2
Term Annotations click to browse term
  biological_process 12483
    metabolic process 7924
      primary metabolic process 6989
        lipid metabolic process 994
          cellular lipid metabolic process 747
            isoprenoid metabolic process 64
              terpenoid metabolic process 50
                diterpenoid metabolic process 45
                  retinoid metabolic process 37
                    retinoic acid metabolic process 15
                      retinoic acid biosynthetic process 9
                        9-cis-retinoic acid biosynthetic process 4
                        negative regulation of retinoic acid biosynthetic process 1
                        positive regulation of retinoic acid biosynthetic process 1
                        regulation of retinoic acid biosynthetic process + 2
paths to the root