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ONTOLOGY REPORT - ANNOTATIONS

Term:lens development in camera-type eye
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Accession:GO:0002088 term browser browse the term
Definition:The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
Synonyms:exact_synonym: lens development;   lens development in camera-style eye


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lens development in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc7 baculoviral IAP repeat-containing 7 acts_upstream_of_or_within ISO MGI:3045749|MGI:5796183 (MGI:5766584|PMID:26218911) RGD PMID:26218911 MGI:5766584 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Casp6 caspase 6 IEP RGD PMID:15161922 RGD:2301319 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Cdk2 cyclin dependent kinase 2 IEP RGD PMID:10620399 RGD:724665 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 IEP RGD PMID:10620399 RGD:724665 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2653120 (MGI:4422144|PMID:19754878)
GO_REF:0000107		 RGD
Ensembl		 PMID:19754878 GO_REF:0000107 MGI:4422144 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033 		JBrowse link
G Cryaa crystallin, alpha A involved_in
acts_upstream_of_or_within		 IEP
IBA
ISO		 PMID:21873635
MGI:1858025|MGI:2653028|MGI:88516 (MGI:2154010|PMID:11687536), (MGI:3617146|PMID:16439475), (MGI:85598|PMID:9023351)		 RGD PMID:9023351 PMID:11687536 PMID:16439475 PMID:8187157 PMID:21873635 MGI:2154010 MGI:3617146 MGI:85598, RGD:1600991, RGD:13792537 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349 		JBrowse link
G Cryab crystallin, alpha B acts_upstream_of_or_within ISO MGI:88515 (MGI:3617146|PMID:16439475) RGD PMID:16439475 MGI:3617146 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cryba1 crystallin, beta A1 involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2753045 PMID:21873635 RGD:1298814, RGD:13792537 NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726 		JBrowse link
G Cryba2 crystallin, beta A2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:4950379 (MGI:4950336|PMID:21212184)		 RGD PMID:21212184 PMID:21873635 MGI:4950336, RGD:13792537 NCBI chr 9:76,447,250...76,457,968
Ensembl chr 9:76,447,251...76,450,460 		JBrowse link
G Cryba4 crystallin, beta A4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:44,378,734...44,393,226
Ensembl chr12:44,378,737...44,393,221 		JBrowse link
G Crybb1 crystallin, beta B1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344 		JBrowse link
G Crybb2 crystallin, beta B2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:43,569,747...43,579,671
Ensembl chr12:43,569,747...43,579,671 		JBrowse link
G Crybb3 crystallin, beta B3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:43,557,103...43,562,120
Ensembl chr12:43,557,103...43,562,120 		JBrowse link
G Crybg3 crystallin beta-gamma domain containing 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:40,749,198...40,861,753
Ensembl chr11:40,749,214...40,861,752 		JBrowse link
G Cryga crystallin, gamma A acts_upstream_of_or_within
involved_in		 IEP
ISO
IBA		 MGI:1856493|MGI:1857595 (MGI:1333159|PMID:6510713), (MGI:65639|PMID:8034315), (MGI:69851|PMID:6877261), (MGI:71783|PMID:7088001)
PMID:21873635		 RGD PMID:6510713 PMID:6877261 PMID:7088001 PMID:8034315 PMID:2338125 More... MGI:1333159 MGI:65639 MGI:69851 MGI:71783, RGD:2303725, RGD:13792537 NCBI chr 9:66,482,176...66,512,873
Ensembl chr 9:66,482,176...66,509,896 		JBrowse link
G Crygb crystallin, gamma B acts_upstream_of_or_within
involved_in		 IEP
ISO
IBA		 MGI:1857597|MGI:3777015 (MGI:3691890|PMID:12426373), (MGI:3776178|PMID:18172107), (MGI:81294|PMID:8626090)
PMID:21873635		 RGD PMID:8626090 PMID:12426373 PMID:18172107 PMID:2338125 PMID:21873635 MGI:3691890 MGI:3776178 MGI:81294, RGD:2303725, RGD:13792537 NCBI chr 9:66,461,460...66,463,520
Ensembl chr 9:66,461,460...66,463,520 		JBrowse link
G Crygc crystallin, gamma C involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2338125 PMID:21873635 RGD:2303725, RGD:13792537 NCBI chr 9:66,451,591...66,453,626
Ensembl chr 9:66,451,593...66,453,626 		JBrowse link
G Crygd crystallin, gamma D acts_upstream_of_or_within
involved_in		 IEP
ISO
IBA		 MGI:1858026|MGI:3762620 (MGI:1354024|PMID:10704279), (MGI:3762268|PMID:17652744)
PMID:21873635		 RGD PMID:10704279 PMID:17652744 PMID:2338125 PMID:21873635 MGI:1354024 MGI:3762268, RGD:2303725, RGD:13792537 NCBI chr 9:66,442,054...66,443,668
Ensembl chr 9:66,442,054...66,444,067 		JBrowse link
G Cryge crystallin, gamma E involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2338125 PMID:21873635 RGD:2303725, RGD:13792537 NCBI chr 9:66,429,924...66,432,521
Ensembl chr 9:66,429,924...66,433,274 		JBrowse link
G Crygf crystallin, gamma F involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2338125 PMID:21873635 RGD:2303725, RGD:13792537 NCBI chr 9:67,448,265...67,450,429
Ensembl chr 9:67,447,954...67,450,429 		JBrowse link
G Crygn crystallin, gamma N involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:10,394,020...10,401,543
Ensembl chr 4:10,394,020...10,401,543 		JBrowse link
G Crygs crystallin, gamma S involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1861635 (MGI:65639|PMID:8034315), (MGI:69851|PMID:6877261)		 RGD PMID:6877261 PMID:8034315 PMID:21873635 MGI:65639 MGI:69851, RGD:13792537 NCBI chr11:78,207,170...78,212,273
Ensembl chr11:78,207,170...78,212,273 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter acts_upstream_of_or_within ISO MGI:2388945 (MGI:5302597|PMID:21897743) RGD PMID:21897743 MGI:5302597 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2680670 (MGI:2682188|PMID:14645510)		 Ensembl
RGD		 PMID:14645510 GO_REF:0000107 MGI:2682188 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Fat1 FAT atypical cadherin 1 involved_in ISO MGI:2662293 (MGI:5766588|PMID:26114487) RGD PMID:26114487 MGI:5766588 NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107 		JBrowse link
G Foxe3 forkhead box E3 involved_in ISS
ISO		 PMID:17064680
(MGI:3703484|PMID:17064680)
GO_REF:0000024
(PMID:27218149)		 RGD
UniProt		 PMID:17064680 PMID:27218149 PMID:17064680 GO_REF:0000024 MGI:3703484, RGD:10047226 NCBI chr 5:128,445,594...128,446,454
Ensembl chr 5:128,445,594...128,446,454 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO MGI:3045749|MGI:3768912 (MGI:5447585|PMID:23136392) RGD PMID:23136392 MGI:5447585 NCBI chr 7:52,711,255...52,792,758
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2181200 (MGI:4354418|PMID:19623612) RGD PMID:19623612 MGI:4354418 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177 (MGI:1267300|PMID:9620080) RGD PMID:9620080 MGI:1267300 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja8 gap junction protein, alpha 8 acts_upstream_of_or_within ISO MGI:1857499 (MGI:69851|PMID:6877261) RGD PMID:6877261 MGI:69851 NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456 		JBrowse link
G Gje1 gap junction protein, epsilon 1 acts_upstream_of_or_within ISO MGI:3529958 (MGI:3795311|PMID:18385072) RGD PMID:18385072 MGI:3795311 NCBI chr 1:9,086,425...9,088,138
Ensembl chr 1:9,086,348...9,088,138 		JBrowse link
G Lim2 lens intrinsic membrane protein 2 acts_upstream_of_or_within ISO MGI:1862040 (MGI:1333159|PMID:6510713), (MGI:69851|PMID:6877261), (MGI:71783|PMID:7088001), (MGI:82332|PMID:8812411) RGD PMID:6510713 PMID:6877261 PMID:7088001 PMID:8812411 MGI:1333159 MGI:69851 MGI:71783 MGI:82332 NCBI chr 1:93,837,597...93,843,769
Ensembl chr 1:93,837,597...93,843,769 		JBrowse link
G Maf MAF bZIP transcription factor acts_upstream_of_or_within ISO MGI:2148635|MGI:2148636|MGI:2148637 (MGI:1340085|PMID:10383433), (MGI:1350584|PMID:10603348), (MGI:3760711|PMID:12835653) RGD PMID:10383433 PMID:10603348 PMID:12835653 MGI:1340085 MGI:1350584 MGI:3760711 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2158098|PMID:11724781)		 UniProt
RGD		 PMID:11724781 GO_REF:0000024 MGI:2158098 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mip major intrinsic protein of lens fiber involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857105 (MGI:55175|PMID:7333462)		 Ensembl
RGD		 PMID:7333462 GO_REF:0000107 MGI:55175 NCBI chr 7:643,502...654,573
Ensembl chr 7:647,315...654,400 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO MGI:2676199 (MGI:3575380|PMID:15716406) RGD PMID:15716406 MGI:3575380 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nhs NHS actin remodeling regulator involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1861111 (MGI:64544|PMID:8282045)		 RGD PMID:8282045 PMID:21873635 MGI:64544, RGD:13792537 NCBI chr  X:32,551,974...32,892,961
Ensembl chr  X:32,552,026...32,889,992 		JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2156742 (MGI:69851|PMID:6877261)		 Ensembl
RGD		 PMID:6877261 GO_REF:0000107 MGI:69851 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pds5a PDS5 cohesin associated factor A acts_upstream_of_or_within ISO MGI:3722688 (MGI:3847057|PMID:19412548) RGD PMID:19412548 MGI:3847057 NCBI chr14:42,551,653...42,651,074
Ensembl chr14:42,552,647...42,648,669 		JBrowse link
G Pds5b PDS5 cohesin associated factor B acts_upstream_of_or_within ISO MGI:3722688 (MGI:3847057|PMID:19412548) RGD PMID:19412548 MGI:3847057 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596 		JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3831639|PMID:19007884), (MGI:4353482|PMID:19334279)		 UniProt
RGD		 PMID:19007884 PMID:19334279 GO_REF:0000024 MGI:3831639 MGI:4353482 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:8812486) RGD PMID:8812486 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Pygo2 pygopus family PHD finger 2 acts_upstream_of_or_within ISO MGI:3712856 (MGI:3712628|PMID:17425782) RGD PMID:17425782 MGI:3712628 NCBI chr 2:174,849,670...174,854,758
Ensembl chr 2:174,849,936...174,854,758 		JBrowse link
G Six3 SIX homeobox 3 involved_in ISO (MGI:1929788|PMID:11139622) RGD PMID:11139622 MGI:1929788 NCBI chr 6:9,040,123...9,043,336
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Six5 SIX homeobox 5 acts_upstream_of_or_within ISO MGI:2148689|MGI:2148692 (MGI:1855730|PMID:10802668), (MGI:1855731|PMID:10802667) RGD PMID:10802667 PMID:10802668 MGI:1855730 MGI:1855731 NCBI chr 1:78,740,812...78,745,890
Ensembl chr 1:78,741,367...78,745,890 		JBrowse link
G Slitrk6 SLIT and NTRK-like family, member 6 acts_upstream_of_or_within ISO MGI:4417931 (MGI:5513052|PMID:23543054) RGD PMID:23543054 MGI:5513052 NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393 		JBrowse link
G Tbc1d20 TBC1 domain family, member 20 acts_upstream_of_or_within ISO MGI:1856684 (MGI:5551670|PMID:24239381) RGD PMID:24239381 MGI:5551670 NCBI chr 3:140,768,537...140,787,010
Ensembl chr 3:140,768,537...140,785,121 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO MGI:4440463 (MGI:4439200|PMID:20159594) RGD PMID:20159594 MGI:4439200 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 acts_upstream_of_or_within ISO (MGI:2151112|PMID:11641223) RGD PMID:11641223 MGI:2151112 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within ISO (MGI:2151112|PMID:11641223) RGD PMID:11641223 MGI:2151112 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
lens fiber cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfsp1 beaded filament structural protein 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(MGI:2673300|PMID:15037121)		 Ensembl
RGD		 PMID:15037121 PMID:21873635 GO_REF:0000107 MGI:2673300, RGD:13792537 NCBI chr 3:131,195,087...131,252,668
Ensembl chr 3:131,195,087...131,229,337 		JBrowse link
G Bfsp2 beaded filament structural protein 2 acts_upstream_of_or_within ISO MGI:2671074 (MGI:2673300|PMID:15037121), (MGI:3717045|PMID:17065509) RGD PMID:15037121 PMID:17065509 MGI:2673300 MGI:3717045 NCBI chr 8:104,006,226...104,063,399
Ensembl chr 8:104,006,226...104,063,399 		JBrowse link
G Crygb crystallin, gamma B acts_upstream_of_or_within ISO MGI:3777015 (MGI:3776178|PMID:18172107) RGD PMID:18172107 MGI:3776178 NCBI chr 9:66,461,460...66,463,520
Ensembl chr 9:66,461,460...66,463,520 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:3044679|MGI:3045749|MGI:95524 (MGI:3796810|PMID:18455718), (MGI:5447585|PMID:23136392) RGD PMID:18455718 PMID:23136392 MGI:3796810 MGI:5447585 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:95523 (MGI:3796810|PMID:18455718) RGD PMID:18455718 MGI:3796810 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO MGI:3045749|MGI:3768912|MGI:97385 (MGI:5447585|PMID:23136392) RGD PMID:23136392 MGI:5447585 NCBI chr 7:52,711,255...52,792,758
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO MGI:2386105 (MGI:4888440|PMID:21118511) RGD PMID:21118511 MGI:4888440 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Tmod1 tropomodulin 1 involved_in ISO UniProtKB:Q6NVD9 (MGI:5475090|PMID:23144950) RGD PMID:23144950 MGI:5475090 NCBI chr 5:60,316,445...60,393,957
Ensembl chr 5:60,338,512...60,393,956 		JBrowse link
G Vim vimentin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2673300|PMID:15037121)		 Ensembl
RGD		 PMID:15037121 GO_REF:0000107 MGI:2673300 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crygd crystallin, gamma D acts_upstream_of_or_within IDA
ISO		 MGI:3762620 (MGI:3762268|PMID:17652744) RGD PMID:17652744 PMID:8575616 MGI:3762268, RGD:1601018 NCBI chr 9:66,442,054...66,443,668
Ensembl chr 9:66,442,054...66,444,067 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 acts_upstream_of_or_within ISO (MGI:3720408|PMID:17215516) RGD PMID:17215516 MGI:3720408 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952 		JBrowse link
G Kdm5b lysine demethylase 5B IEP RGD PMID:24142921 RGD:9587771 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Maf MAF bZIP transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:2148636|MGI:2148637 (MGI:1340085|PMID:10383433), (MGI:3760711|PMID:12835653)
PMID:21873635		 Ensembl
RGD		 PMID:10383433 PMID:12835653 PMID:21873635 GO_REF:0000107 MGI:1340085 MGI:3760711, RGD:13792537 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in ISO (MGI:4457460|PMID:20181838) RGD PMID:20181838 MGI:4457460 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:1100860 (MGI:5447585|PMID:23136392) RGD PMID:23136392 MGI:5447585 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in ISO (MGI:3831639|PMID:19007884) RGD PMID:19007884 MGI:3831639 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892 		JBrowse link
G Plaat1 phospholipase A and acyltransferase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:71,517,492...71,537,142
Ensembl chr11:71,517,493...71,527,020 		JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6710184|PMID:33854238)		 UniProt
RGD		 PMID:33854238 GO_REF:0000024 MGI:6710184 NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667 		JBrowse link
G Six3 SIX homeobox 3 involved_in ISO (MGI:2181466|PMID:12072567) RGD PMID:12072567 MGI:2181466 NCBI chr 6:9,040,123...9,043,336
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO (MGI:3720408|PMID:17215516) RGD PMID:17215516 MGI:3720408 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 IEP RGD PMID:16043861 RGD:2315033 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO (MGI:3720408|PMID:17215516) RGD PMID:17215516 MGI:3720408 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tdrd7 tudor domain containing 7 involved_in ISO
ISS
IBA		 (PMID:21436445)
GO_REF:0000024
PMID:21873635
(MGI:4943339|PMID:21436445)		 RGD
UniProt		 PMID:21436445 PMID:21873635 GO_REF:0000024 MGI:4943339, RGD:13792537 NCBI chr 5:60,238,742...60,312,548
Ensembl chr 5:60,238,678...60,312,544 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO (MGI:3720408|PMID:17215516) RGD PMID:17215516 MGI:3720408 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
lens fiber cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (MGI:3525751|PMID:15572692) RGD PMID:15572692 MGI:3525751 NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:1339872|PMID:10096021), (MGI:1859108|PMID:10885750), (MGI:2158533|PMID:11806972)		 UniProt
RGD		 PMID:10096021 PMID:10885750 PMID:11806972 GO_REF:0000024 MGI:1339872 MGI:1859108 MGI:2158533 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Cryaa crystallin, alpha A acts_upstream_of_or_within ISO MGI:3665275|MGI:3777403 (MGI:3655912|PMID:16799046), (MGI:3775669|PMID:18056999) RGD PMID:16799046 PMID:18056999 MGI:3655912 MGI:3775669 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349 		JBrowse link
G Crygb crystallin, gamma B acts_upstream_of_or_within ISO MGI:1857597 (MGI:3691890|PMID:12426373), (MGI:81294|PMID:8626090) RGD PMID:8626090 PMID:12426373 MGI:3691890 MGI:81294 NCBI chr 9:66,461,460...66,463,520
Ensembl chr 9:66,461,460...66,463,520 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (MGI:3831440|PMID:18948590) RGD PMID:18948590 MGI:3831440 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:11850194)
(MGI:1332720|PMID:10080188)		 RGD PMID:10080188 PMID:11850194 MGI:1332720 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Tbc1d20 TBC1 domain family, member 20 acts_upstream_of_or_within ISO MGI:1856684 (MGI:5551670|PMID:24239381) RGD PMID:24239381 MGI:5551670 NCBI chr 3:140,768,537...140,787,010
Ensembl chr 3:140,768,537...140,785,121 		JBrowse link
lens induction in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857137 (MGI:1316914|PMID:9851982)		 Ensembl
RGD		 PMID:9851982 GO_REF:0000107 MGI:1316914 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4818711|PMID:20579985)		 Ensembl
RGD		 PMID:20579985 GO_REF:0000107 MGI:4818711 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (MGI:4818711|PMID:20579985) RGD PMID:20579985 MGI:4818711 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 acts_upstream_of_or_within ISO MGI:98364 (MGI:3701404|PMID:17140559) RGD PMID:17140559 MGI:3701404 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363 		JBrowse link
G Six3 SIX homeobox 3 acts_upstream_of_or_within ISO MGI:3693322 (MGI:3692850|PMID:17066077) RGD PMID:17066077 MGI:3692850 NCBI chr 6:9,040,123...9,043,336
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO MGI:101898 (MGI:3701404|PMID:17140559) RGD PMID:17140559 MGI:3701404 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:1888387 (MGI:1347707|PMID:10571739) RGD PMID:10571739 MGI:1347707 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
lens morphogenesis in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar3 BCAR3 adaptor protein, NSP family member acts_upstream_of_or_within ISO MGI:4359826 (MGI:4358852|PMID:19365570) RGD PMID:19365570 MGI:4358852 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:3045749|MGI:3696062 (MGI:3807101|PMID:18653562) RGD PMID:18653562 MGI:3807101 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cryaa crystallin, alpha A acts_upstream_of_or_within ISO MGI:1858023|MGI:3665274|MGI:3665275 (MGI:3655912|PMID:16799046), (MGI:82388|PMID:8812430) RGD PMID:8812430 PMID:16799046 MGI:3655912 MGI:82388 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2148567|MGI:3045749 (MGI:3603687|PMID:16102745)
GO_REF:0000107		 RGD
Ensembl		 PMID:16102745 GO_REF:0000107 MGI:3603687 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (MGI:1933072|PMID:11290300) RGD PMID:11290300 MGI:1933072 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Lctl lactase-like involved_in ISO (MGI:6274960|PMID:29425878) RGD PMID:29425878 MGI:6274960 NCBI chr 8:64,618,356...64,654,851
Ensembl chr 8:64,618,350...64,639,357 		JBrowse link
G Meis1 Meis homeobox 1 acts_upstream_of_or_within ISO MGI:3029063 (MGI:3028436|PMID:14713950) RGD PMID:14713950 MGI:3028436 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265 		JBrowse link
G Nectin1 nectin cell adhesion molecule 1 acts_upstream_of_or_within ISO MGI:3605480 (MGI:3604842|PMID:15728677) RGD PMID:15728677 MGI:3604842 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787 		JBrowse link
G Nectin3 nectin cell adhesion molecule 3 acts_upstream_of_or_within ISO MGI:3605481 (MGI:3604842|PMID:15728677) RGD PMID:15728677 MGI:3604842 NCBI chr11:54,362,712...54,461,316
Ensembl chr11:54,364,487...54,462,519 		JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4353482|PMID:19334279)		 UniProt
RGD		 PMID:19334279 GO_REF:0000024 MGI:4353482 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:1332720|PMID:10080188) RGD PMID:10080188 MGI:1332720 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Ski Ski proto-oncogene acts_upstream_of_or_within ISO MGI:2177555 (MGI:3693412|PMID:17003410) RGD PMID:17003410 MGI:3693412 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733 		JBrowse link
G Sox1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO MGI:2137412 (MGI:1201714|PMID:9512512) RGD PMID:9512512 MGI:1201714 NCBI chr16:77,134,795...77,139,628
Ensembl chr16:77,137,584...77,138,762 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3797299|PMID:18423449)		 UniProt
RGD		 PMID:18423449 GO_REF:0000024 MGI:3797299 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Tdrd7 tudor domain containing 7 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:4943339|PMID:21436445)
(PMID:21436445)		 UniProt
RGD		 PMID:21436445 PMID:21873635 GO_REF:0000024 MGI:4943339, RGD:13792537 NCBI chr 5:60,238,742...60,312,548
Ensembl chr 5:60,238,678...60,312,544 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:2176682 (MGI:1329246|PMID:9918694), (MGI:3774683|PMID:18224708) RGD PMID:9918694 PMID:18224708 MGI:1329246 MGI:3774683 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
negative regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxe3 forkhead box E3 involved_in ISS
ISO		 PMID:16199865
(MGI:1352262|PMID:10652278), (MGI:1861492|PMID:10890982), (MGI:3603877|PMID:16199865)		 RGD PMID:10652278 PMID:10890982 PMID:16199865 PMID:16199865 MGI:1352262 MGI:1861492 MGI:3603877, RGD:10047273 NCBI chr 5:128,445,594...128,446,454
Ensembl chr 5:128,445,594...128,446,454 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6414698|PMID:29501879)		 UniProt
RGD		 PMID:29501879 GO_REF:0000024 MGI:6414698 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
positive regulation of lens epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxe3 forkhead box E3 involved_in ISS
ISO		 PMID:16199865
(PMID:22527307)
(MGI:1352262|PMID:10652278), (MGI:3603877|PMID:16199865)		 RGD PMID:10652278 PMID:16199865 PMID:22527307 PMID:16199865 PMID:22527307 MGI:1352262 MGI:3603877, RGD:10047273, RGD:10047255 NCBI chr 5:128,445,594...128,446,454
Ensembl chr 5:128,445,594...128,446,454 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3797299|PMID:18423449)		 UniProt
RGD		 PMID:18423449 GO_REF:0000024 MGI:3797299 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
positive regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29501879)		 UniProt
RGD		 PMID:29501879 GO_REF:0000024 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in ISO (MGI:3604916|PMID:16162653) RGD PMID:16162653 MGI:3604916 NCBI chr 3:29,219,765...29,342,094
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B acts_upstream_of_or_within ISO MGI:104564 (MGI:1309707|PMID:9784491) RGD PMID:9784491 MGI:1309707 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C acts_upstream_of_or_within ISO MGI:104565 (MGI:1309707|PMID:9784491) RGD PMID:9784491 MGI:1309707 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    developmental process 7023
      anatomical structure development 6456
        lens development in camera-type eye 96
          lens epithelial cell proliferation + 2
          lens fiber cell differentiation + 40
          lens morphogenesis in camera-type eye + 27
Path 2
Term Annotations click to browse term
  biological_process 19903
    developmental process 7023
      anatomical structure development 6456
        multicellular organism development 5242
          system development 4503
            sensory system development 488
              visual system development 483
                eye development 480
                  camera-type eye development 430
                    lens development in camera-type eye 96
                      lens epithelial cell proliferation + 2
                      lens fiber cell differentiation + 40
                      lens morphogenesis in camera-type eye + 27
paths to the root