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ONTOLOGY REPORT - ANNOTATIONS

Term:lens development in camera-type eye
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Accession:GO:0002088 term browser browse the term
Definition:The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
Synonyms:exact_synonym: lens development;   lens development in camera-style eye

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lens development in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07033887.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr11:42,936,028...42,944,942 JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 ISO MGI:3045749|MGI:5796183 (MGI:5766584|PMID:26218911) RGD PMID:26218911 MGI:5766584 NCBI chr 3:176,438,335...176,443,864
Ensembl chr 3:176,439,199...176,443,195 		JBrowse link
G Casp6 caspase 6 IEP RGD PMID:15161922 RGD:2301319 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967 		JBrowse link
G Cdk2 cyclin dependent kinase 2 IEP RGD PMID:10620399 RGD:724665 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 IEP RGD PMID:10620399 RGD:724665 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated involved_in IEA
ISO		 GO_REF:0000107
MGI:2653120 (MGI:4422144|PMID:19754878)		 Ensembl
RGD		 PMID:19754878 GO_REF:0000107 MGI:4422144 NCBI chr 8:36,625,757...36,712,091
Ensembl chr 8:36,625,733...36,710,949 		JBrowse link
G Cryaa crystallin, alpha A IEP
ISO		 MGI:1858025|MGI:2653028|MGI:88516 (MGI:2154010|PMID:11687536), (MGI:3617146|PMID:16439475), (MGI:85598|PMID:9023351) RGD PMID:9023351 PMID:11687536 PMID:16439475, PMID:8187157 MGI:2154010 MGI:3617146 MGI:85598, RGD:1600991 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187 		JBrowse link
G Cryab crystallin, alpha B ISO MGI:88515 (MGI:3617146|PMID:16439475) RGD PMID:16439475 MGI:3617146 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545 		JBrowse link
G Cryba1 crystallin, beta A1 IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2753045, PMID:21873635 RGD:1298814, RGD:13792537 NCBI chr10:65,160,777...65,167,504
Ensembl chr10:65,161,152...65,167,494 		JBrowse link
G Cryba2 crystallin, beta A2 involved_in ISO
IBA		 MGI:4950379 (MGI:4950336|PMID:21212184)
PMID:21873635		 RGD PMID:21212184, PMID:21873635, PMID:21873635 MGI:4950336, RGD:13792537, RGD:13792537 NCBI chr 9:82,151,056...82,154,266
Ensembl chr 9:82,151,057...82,154,266 		JBrowse link
G Cryba4 crystallin, beta A4 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:50,407,843...50,414,434
Ensembl chr12:50,407,843...50,414,432 		JBrowse link
G Crybb1 crystallin, beta B1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:50,390,939...50,404,550
Ensembl chr12:50,390,940...50,404,550 		JBrowse link
G Crybb2 crystallin, beta B2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:49,577,580...49,588,555
Ensembl chr12:49,578,633...49,588,555 		JBrowse link
G Crybb3 crystallin, beta B3 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:49,564,991...49,571,008
Ensembl chr12:49,565,992...49,571,006 		JBrowse link
G Crybg3 crystallin beta-gamma domain containing 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr11:42,895,610...43,006,568
Ensembl chr11:42,945,084...43,005,097 		JBrowse link
G Cryga crystallin, gamma A involved_in IEP
IBA
ISO		 PMID:21873635
MGI:1856493|MGI:1857595 (MGI:1333159|PMID:6510713), (MGI:65639|PMID:8034315), (MGI:69851|PMID:6877261), (MGI:71783|PMID:7088001)		 RGD PMID:6510713 PMID:6877261 PMID:7088001 PMID:8034315, PMID:2338125, PMID:21873635, PMID:21873635 MGI:1333159 MGI:65639 MGI:69851 MGI:71783, RGD:2303725, RGD:13792537, RGD:13792537 NCBI chr 9:71,828,308...71,855,900
Ensembl chr 9:71,835,883...71,852,113
Ensembl chr 9:71,835,883...71,852,113 		JBrowse link
G Crygb crystallin, gamma B involved_in IEP
IBA
ISO		 PMID:21873635
MGI:1857597|MGI:3777015 (MGI:3691890|PMID:12426373), (MGI:3776178|PMID:18172107), (MGI:81294|PMID:8626090)		 RGD PMID:8626090 PMID:12426373 PMID:18172107, PMID:2338125, PMID:21873635, PMID:21873635 MGI:3691890 MGI:3776178 MGI:81294, RGD:2303725, RGD:13792537, RGD:13792537 NCBI chr 9:71,796,204...71,798,265
Ensembl chr 9:71,796,204...71,798,265 		JBrowse link
G Crygc crystallin, gamma C involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2338125, PMID:21873635, PMID:21873635 RGD:2303725, RGD:13792537, RGD:13792537 NCBI chr 9:71,786,246...71,788,281
Ensembl chr 9:71,786,248...71,788,281 		JBrowse link
G Crygd crystallin, gamma D involved_in IEP
IBA
ISO		 PMID:21873635
MGI:1858026|MGI:3762620 (MGI:1354024|PMID:10704279), (MGI:3762268|PMID:17652744)		 RGD PMID:10704279 PMID:17652744, PMID:2338125, PMID:21873635, PMID:21873635 MGI:1354024 MGI:3762268, RGD:2303725, RGD:13792537, RGD:13792537 NCBI chr 9:71,776,568...71,778,323
Ensembl chr 9:71,764,318...71,778,323 		JBrowse link
G Cryge crystallin, gamma E involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2338125, PMID:21873635, PMID:21873635 RGD:2303725, RGD:13792537, RGD:13792537 NCBI chr 9:71,764,317...71,767,045 JBrowse link
G Crygf crystallin, gamma F involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2338125, PMID:21873635, PMID:21873635 RGD:2303725, RGD:13792537, RGD:13792537 NCBI chr 9:72,933,304...72,935,468
Ensembl chr 9:72,933,304...72,935,468 		JBrowse link
G Crygn crystallin, gamma N involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:6,900,811...6,909,167
Ensembl chr 4:6,903,198...6,909,167 		JBrowse link
G Crygs crystallin, gamma S involved_in ISO
IBA		 MGI:1861635 (MGI:65639|PMID:8034315), (MGI:69851|PMID:6877261)
PMID:21873635		 RGD PMID:6877261 PMID:8034315, PMID:21873635, PMID:21873635 MGI:65639 MGI:69851, RGD:13792537, RGD:13792537 NCBI chr11:81,796,891...81,802,172
Ensembl chr11:81,796,891...81,802,172 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter ISO MGI:2388945 (MGI:5302597|PMID:21897743) RGD PMID:21897743 MGI:5302597 NCBI chr10:59,749,250...59,772,475
Ensembl chr10:59,749,256...59,764,868 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:2680670 (MGI:2682188|PMID:14645510)		 Ensembl
RGD		 PMID:14645510 GO_REF:0000107 MGI:2682188 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895 		JBrowse link
G Fat1 FAT atypical cadherin 1 ISO MGI:2662293 (MGI:5766588|PMID:26114487) RGD PMID:26114487 MGI:5766588 NCBI chr16:50,372,150...50,501,716
Ensembl chr16:50,372,128...50,501,921 		JBrowse link
G Foxe3 forkhead box E3 involved_in ISO
ISS		 (PMID:27218149)
GO_REF:0000024
PMID:17064680
(MGI:3703484|PMID:17064680)		 RGD
UniProt		 PMID:17064680 PMID:27218149, PMID:17064680, PMID:17064680 GO_REF:0000024 MGI:3703484, RGD:10047226, RGD:10047226 NCBI chr 5:133,724,796...133,725,656
Ensembl chr 5:133,724,796...133,725,656 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 ISO MGI:3045749|MGI:3768912 (MGI:5447585|PMID:23136392) RGD PMID:23136392 MGI:5447585 NCBI chr 7:60,128,506...60,210,482
Ensembl chr 7:60,128,508...60,210,518 		JBrowse link
G Gata3 GATA binding protein 3 ISO MGI:2181200 (MGI:4354418|PMID:19623612) RGD PMID:19623612 MGI:4354418 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681 		JBrowse link
G Gja1 gap junction protein, alpha 1 ISO MGI:1857177 (MGI:1267300|PMID:9620080) RGD PMID:9620080 MGI:1267300 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089 		JBrowse link
G Gja8 gap junction protein, alpha 8 ISO MGI:1857499 (MGI:69851|PMID:6877261) RGD PMID:6877261 MGI:69851 NCBI chr 2:199,050,854...199,052,470
Ensembl chr 2:199,050,854...199,052,470 		JBrowse link
G Gje1 gap junction protein, epsilon 1 ISO MGI:3529958 (MGI:3795311|PMID:18385072) RGD PMID:18385072 MGI:3795311 NCBI chr 1:8,883,767...8,887,721
Ensembl chr 1:8,883,961...8,885,967 		JBrowse link
G Lim2 lens intrinsic membrane protein 2 ISO MGI:1862040 (MGI:1333159|PMID:6510713), (MGI:69851|PMID:6877261), (MGI:71783|PMID:7088001), (MGI:82332|PMID:8812411) RGD PMID:6510713 PMID:6877261 PMID:7088001 PMID:8812411 MGI:1333159 MGI:69851 MGI:71783 MGI:82332 NCBI chr 1:98,495,082...98,501,248
Ensembl chr 1:98,495,082...98,501,249 		JBrowse link
G Maf MAF bZIP transcription factor ISO MGI:2148635|MGI:2148636|MGI:2148637 (MGI:1340085|PMID:10383433), (MGI:1350584|PMID:10603348), (MGI:3760711|PMID:12835653) RGD PMID:10383433 PMID:10603348 PMID:12835653 MGI:1340085 MGI:1350584 MGI:3760711 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748 		JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2158098|PMID:11724781)		 UniProt
RGD		 PMID:11724781 GO_REF:0000024 MGI:2158098 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880 		JBrowse link
G Mip major intrinsic protein of lens fiber involved_in IEA
ISO		 GO_REF:0000107
MGI:1857105 (MGI:55175|PMID:7333462)		 Ensembl
RGD		 PMID:7333462 GO_REF:0000107 MGI:55175 NCBI chr 7:2,635,743...2,642,995
Ensembl chr 7:2,635,743...2,642,848 		JBrowse link
G Nhs NHS actin remodeling regulator involved_in ISO
IBA		 MGI:1861111 (MGI:64544|PMID:8282045)
PMID:21873635		 RGD PMID:8282045, PMID:21873635, PMID:21873635 MGI:64544, RGD:13792537, RGD:13792537 NCBI chr  X:34,312,102...34,675,912
Ensembl chr  X:34,623,405...34,673,742 		JBrowse link
G Pax6 paired box 6 involved_in IEA
ISO		 GO_REF:0000107
MGI:2156742 (MGI:69851|PMID:6877261)		 Ensembl
RGD		 PMID:6877261 GO_REF:0000107 MGI:69851 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624 		JBrowse link
G Pds5a PDS5 cohesin associated factor A ISO MGI:3722688 (MGI:3847057|PMID:19412548) RGD PMID:19412548 MGI:3847057 NCBI chr14:44,185,445...44,282,308
Ensembl chr14:44,185,446...44,280,079 		JBrowse link
G Pds5b PDS5 cohesin associated factor B ISO MGI:3722688 (MGI:3847057|PMID:19412548) RGD PMID:19412548 MGI:3847057 NCBI chr12:659,995...794,042
Ensembl chr12:660,011...794,042 		JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3831639|PMID:19007884), (MGI:4353482|PMID:19334279)		 UniProt
RGD		 PMID:19007884 PMID:19334279 GO_REF:0000024 MGI:3831639 MGI:4353482 NCBI chr 1:265,886,766...265,899,947
Ensembl chr 1:265,887,230...265,899,958 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:8812486) RGD PMID:8812486 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294 		JBrowse link
G Pygo2 pygopus family PHD finger 2 ISO MGI:3712856 (MGI:3712628|PMID:17425782) RGD PMID:17425782 MGI:3712628 NCBI chr 2:188,757,167...188,762,285
Ensembl chr 2:188,757,489...188,762,282 		JBrowse link
G Six3 SIX homeobox 3 ISO (MGI:1929788|PMID:11139622) RGD PMID:11139622 MGI:1929788 NCBI chr 6:8,886,730...8,891,094
Ensembl chr 6:8,886,591...8,889,925 		JBrowse link
G Six5 SIX homeobox 5 ISO MGI:2148689|MGI:2148692 (MGI:1855730|PMID:10802668), (MGI:1855731|PMID:10802667) RGD PMID:10802667 PMID:10802668 MGI:1855730 MGI:1855731 NCBI chr 1:80,000,106...80,005,303
Ensembl chr 1:80,000,165...80,003,232 		JBrowse link
G Slitrk6 SLIT and NTRK-like family, member 6 ISO MGI:4417931 (MGI:5513052|PMID:23543054) RGD PMID:23543054 MGI:5513052 NCBI chr15:95,507,632...95,514,259
Ensembl chr15:95,507,640...95,514,259 		JBrowse link
G Tbc1d20 TBC1 domain family, member 20 ISO MGI:1856684 (MGI:5551670|PMID:24239381) RGD PMID:24239381 MGI:5551670 NCBI chr 3:147,772,006...147,790,946
Ensembl chr 3:147,772,165...147,789,158 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 ISO MGI:4440463 (MGI:4439200|PMID:20159594) RGD PMID:20159594 MGI:4439200 NCBI chr20:37,463,879...37,701,268
Ensembl chr20:37,465,278...37,700,937 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO (MGI:2151112|PMID:11641223) RGD PMID:11641223 MGI:2151112 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO (MGI:2151112|PMID:11641223) RGD PMID:11641223 MGI:2151112 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
lens fiber cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfsp1 beaded filament structural protein 1 involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(MGI:2673300|PMID:15037121)		 Ensembl
RGD		 PMID:15037121, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:2673300, RGD:13792537, RGD:13792537 NCBI chr 3:137,935,345...137,992,652
Ensembl chr 3:137,935,345...137,969,658 		JBrowse link
G Bfsp2 beaded filament structural protein 2 ISO MGI:2671074 (MGI:2673300|PMID:15037121), (MGI:3717045|PMID:17065509) RGD PMID:15037121 PMID:17065509 MGI:2673300 MGI:3717045 NCBI chr 8:111,908,614...111,965,889
Ensembl chr 8:111,908,614...111,965,889 		JBrowse link
G Crygb crystallin, gamma B ISO MGI:3777015 (MGI:3776178|PMID:18172107) RGD PMID:18172107 MGI:3776178 NCBI chr 9:71,796,204...71,798,265
Ensembl chr 9:71,796,204...71,798,265 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO MGI:3044679|MGI:3045749|MGI:95524 (MGI:3796810|PMID:18455718), (MGI:5447585|PMID:23136392) RGD PMID:18455718 PMID:23136392 MGI:3796810 MGI:5447585 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO MGI:95523 (MGI:3796810|PMID:18455718) RGD PMID:18455718 MGI:3796810 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 ISO MGI:3045749|MGI:3768912|MGI:97385 (MGI:5447585|PMID:23136392) RGD PMID:23136392 MGI:5447585 NCBI chr 7:60,128,506...60,210,482
Ensembl chr 7:60,128,508...60,210,518 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO MGI:2386105 (MGI:4888440|PMID:21118511) RGD PMID:21118511 MGI:4888440 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468 		JBrowse link
G Tmod1 tropomodulin 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q6NVD9 (MGI:5475090|PMID:23144950)		 Ensembl
RGD		 PMID:23144950 GO_REF:0000107 MGI:5475090 NCBI chr 5:61,635,244...61,712,052
Ensembl chr 5:61,657,507...61,712,051 		JBrowse link
G Vim vimentin involved_in IEA
ISO		 GO_REF:0000107
(MGI:2673300|PMID:15037121)		 Ensembl
RGD		 PMID:15037121 GO_REF:0000107 MGI:2673300 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212 		JBrowse link
lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crygd crystallin, gamma D IDA
ISO		 MGI:3762620 (MGI:3762268|PMID:17652744) RGD PMID:17652744, PMID:8575616 MGI:3762268, RGD:1601018 NCBI chr 9:71,776,568...71,778,323
Ensembl chr 9:71,764,318...71,778,323 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 ISO (MGI:3720408|PMID:17215516) RGD PMID:17215516 MGI:3720408 NCBI chr 7:11,201,690...11,213,614
Ensembl chr 7:11,201,690...11,213,613 		JBrowse link
G Kdm5b lysine demethylase 5B IEP RGD PMID:24142921 RGD:9587771 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357 		JBrowse link
G Maf MAF bZIP transcription factor involved_in ISO
IEA
IBA		 MGI:2148636|MGI:2148637 (MGI:1340085|PMID:10383433), (MGI:3760711|PMID:12835653)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:10383433 PMID:12835653, PMID:21873635 GO_REF:0000107 MGI:1340085 MGI:3760711, RGD:13792537 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748 		JBrowse link
G Nf2 neurofibromin 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4457460|PMID:20181838)		 Ensembl
RGD		 PMID:20181838 GO_REF:0000107 MGI:4457460 NCBI chr14:84,996,905...85,088,547
Ensembl chr14:84,996,905...85,088,523 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO MGI:1100860 (MGI:5447585|PMID:23136392) RGD PMID:23136392 MGI:5447585 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503 		JBrowse link
G Pitx3 paired-like homeodomain 3 ISO (MGI:3831639|PMID:19007884) RGD PMID:19007884 MGI:3831639 NCBI chr 1:265,886,766...265,899,947
Ensembl chr 1:265,887,230...265,899,958 		JBrowse link
G Six3 SIX homeobox 3 ISO (MGI:2181466|PMID:12072567) RGD PMID:12072567 MGI:2181466 NCBI chr 6:8,886,730...8,891,094
Ensembl chr 6:8,886,591...8,889,925 		JBrowse link
G Skil SKI-like proto-oncogene ISO (MGI:3720408|PMID:17215516) RGD PMID:17215516 MGI:3720408 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 IEP RGD PMID:16043861 RGD:2315033 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162 		JBrowse link
G Smad3 SMAD family member 3 ISO (MGI:3720408|PMID:17215516) RGD PMID:17215516 MGI:3720408 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
G Tdrd7 tudor domain containing 7 involved_in ISO
ISS		 (PMID:21436445)
GO_REF:0000024
(MGI:4943339|PMID:21436445)		 RGD
UniProt		 PMID:21436445 GO_REF:0000024 MGI:4943339 NCBI chr 5:61,557,909...61,631,719
Ensembl chr 5:61,564,864...61,631,710 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (MGI:3720408|PMID:17215516) RGD PMID:17215516 MGI:3720408 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
lens fiber cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 ISO (MGI:3525751|PMID:15572692) RGD PMID:15572692 MGI:3525751 NCBI chr 9:67,234,612...67,284,504
Ensembl chr 9:67,234,303...67,282,600 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:1339872|PMID:10096021), (MGI:1859108|PMID:10885750), (MGI:2158533|PMID:11806972)		 UniProt
RGD		 PMID:10096021 PMID:10885750 PMID:11806972 GO_REF:0000024 MGI:1339872 MGI:1859108 MGI:2158533 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Cryaa crystallin, alpha A ISO MGI:3665275|MGI:3777403 (MGI:3655912|PMID:16799046), (MGI:3775669|PMID:18056999) RGD PMID:16799046 PMID:18056999 MGI:3655912 MGI:3775669 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187 		JBrowse link
G Crygb crystallin, gamma B ISO MGI:1857597 (MGI:3691890|PMID:12426373), (MGI:81294|PMID:8626090) RGD PMID:8626090 PMID:12426373 MGI:3691890 MGI:81294 NCBI chr 9:71,796,204...71,798,265
Ensembl chr 9:71,796,204...71,798,265 		JBrowse link
G Epha2 Eph receptor A2 ISO (MGI:3831440|PMID:18948590) RGD PMID:18948590 MGI:3831440 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:11850194)
(MGI:1332720|PMID:10080188)		 RGD PMID:10080188 PMID:11850194 MGI:1332720 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294 		JBrowse link
G Tbc1d20 TBC1 domain family, member 20 ISO MGI:1856684 (MGI:5551670|PMID:24239381) RGD PMID:24239381 MGI:5551670 NCBI chr 3:147,772,006...147,790,946
Ensembl chr 3:147,772,165...147,789,158 		JBrowse link
lens induction in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
MGI:1857137 (MGI:1316914|PMID:9851982)		 Ensembl
RGD		 PMID:9851982 GO_REF:0000107 MGI:1316914 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4818711|PMID:20579985)		 Ensembl
RGD		 PMID:20579985 GO_REF:0000107 MGI:4818711 NCBI chr 2:206,224,015...206,274,910
Ensembl chr 2:206,224,015...206,274,079 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 ISO (MGI:4818711|PMID:20579985) RGD PMID:20579985 MGI:4818711 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 ISO MGI:98364 (MGI:3701404|PMID:17140559) RGD PMID:17140559 MGI:3701404 NCBI chr13:84,075,316...84,217,368
Ensembl chr13:84,083,632...84,217,366 		JBrowse link
G Six3 SIX homeobox 3 ISO MGI:3693322 (MGI:3692850|PMID:17066077) RGD PMID:17066077 MGI:3692850 NCBI chr 6:8,886,730...8,891,094
Ensembl chr 6:8,886,591...8,889,925 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO MGI:101898 (MGI:3701404|PMID:17140559) RGD PMID:17140559 MGI:3701404 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545 		JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO MGI:1888387 (MGI:1347707|PMID:10571739) RGD PMID:10571739 MGI:1347707 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457 		JBrowse link
lens morphogenesis in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar3 BCAR3 adaptor protein, NSP family member ISO MGI:4359826 (MGI:4358852|PMID:19365570) RGD PMID:19365570 MGI:4358852 NCBI chr 2:226,563,050...226,679,449
Ensembl chr 2:226,563,050...226,679,438 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ISO MGI:3045749|MGI:3696062 (MGI:3807101|PMID:18653562) RGD PMID:18653562 MGI:3807101 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786 		JBrowse link
G Cryaa crystallin, alpha A ISO MGI:1858023|MGI:3665274|MGI:3665275 (MGI:3655912|PMID:16799046), (MGI:82388|PMID:8812430) RGD PMID:8812430 PMID:16799046 MGI:3655912 MGI:82388 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:2148567|MGI:3045749 (MGI:3603687|PMID:16102745)		 Ensembl
RGD		 PMID:16102745 GO_REF:0000107 MGI:3603687 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO (MGI:1933072|PMID:11290300) RGD PMID:11290300 MGI:1933072 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706 		JBrowse link
G Lctl lactase-like ISO (MGI:6274960|PMID:29425878) RGD PMID:29425878 MGI:6274960 NCBI chr 8:69,070,340...69,090,405
Ensembl chr 8:69,070,994...69,086,992 		JBrowse link
G Meis1 Meis homeobox 1 ISO MGI:3029063 (MGI:3028436|PMID:14713950) RGD PMID:14713950 MGI:3028436 NCBI chr14:103,182,178...103,321,809
Ensembl chr14:103,181,281...103,321,270 		JBrowse link
G Nectin1 nectin cell adhesion molecule 1 ISO MGI:3605480 (MGI:3604842|PMID:15728677) RGD PMID:15728677 MGI:3604842 NCBI chr 8:48,094,233...48,198,499
Ensembl chr 8:48,094,673...48,157,305 		JBrowse link
G Nectin3 nectin cell adhesion molecule 3 ISO MGI:3605481 (MGI:3604842|PMID:15728677) RGD PMID:15728677 MGI:3604842 NCBI chr11:57,897,879...57,995,193
Ensembl chr11:57,897,879...57,993,548 		JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4353482|PMID:19334279)		 UniProt
RGD		 PMID:19334279 GO_REF:0000024 MGI:4353482 NCBI chr 1:265,886,766...265,899,947
Ensembl chr 1:265,887,230...265,899,958 		JBrowse link
G Prox1 prospero homeobox 1 ISO (MGI:1332720|PMID:10080188) RGD PMID:10080188 MGI:1332720 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294 		JBrowse link
G Ski SKI proto-oncogene ISO MGI:2177555 (MGI:3693412|PMID:17003410) RGD PMID:17003410 MGI:3693412 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899 		JBrowse link
G Sox1 SRY-box transcription factor 1 ISO MGI:2137412 (MGI:1201714|PMID:9512512) RGD PMID:9512512 MGI:1201714
G Sox11 SRY-box transcription factor 11 ISS
ISO		 GO_REF:0000024
(MGI:3797299|PMID:18423449)		 UniProt
RGD		 PMID:18423449 GO_REF:0000024 MGI:3797299 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983 		JBrowse link
G Tdrd7 tudor domain containing 7 involved_in ISO
ISS		 (PMID:21436445)
GO_REF:0000024
(MGI:4943339|PMID:21436445)		 RGD
UniProt		 PMID:21436445 GO_REF:0000024 MGI:4943339 NCBI chr 5:61,557,909...61,631,719
Ensembl chr 5:61,564,864...61,631,710 		JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO MGI:2176682 (MGI:1329246|PMID:9918694), (MGI:3774683|PMID:18224708) RGD PMID:9918694 PMID:18224708 MGI:1329246 MGI:3774683 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457 		JBrowse link
negative regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxe3 forkhead box E3 involved_in ISS
ISO		 PMID:16199865
(MGI:1352262|PMID:10652278), (MGI:1861492|PMID:10890982), (MGI:3603877|PMID:16199865)		 RGD PMID:10652278 PMID:10890982 PMID:16199865, PMID:16199865, PMID:16199865 MGI:1352262 MGI:1861492 MGI:3603877, RGD:10047273, RGD:10047273 NCBI chr 5:133,724,796...133,725,656
Ensembl chr 5:133,724,796...133,725,656 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr 3:108,795,337...108,861,650
Ensembl chr 3:108,795,235...108,857,556 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6414698|PMID:29501879)		 UniProt
RGD		 PMID:29501879 GO_REF:0000024 MGI:6414698 NCBI chr14:104,268,362...104,290,206
Ensembl chr14:104,191,517...104,290,456 		JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr 1:88,101,213...88,112,719
Ensembl chr 1:88,103,719...88,112,683 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 ISO (MGI:6414698|PMID:29501879) RGD PMID:29501879 MGI:6414698 NCBI chr15:90,172,769...90,177,823
Ensembl chr15:90,172,975...90,175,802 		JBrowse link
positive regulation of lens epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxe3 forkhead box E3 involved_in ISO
ISS		 (PMID:22527307)
PMID:16199865
(MGI:1352262|PMID:10652278), (MGI:3603877|PMID:16199865)		 RGD PMID:10652278 PMID:16199865 PMID:22527307, PMID:16199865, PMID:22527307, PMID:16199865, PMID:22527307 MGI:1352262 MGI:3603877, RGD:10047273, RGD:10047255, RGD:10047273, RGD:10047255 NCBI chr 5:133,724,796...133,725,656
Ensembl chr 5:133,724,796...133,725,656 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3797299|PMID:18423449)		 UniProt
RGD		 PMID:18423449 GO_REF:0000024 MGI:3797299 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983 		JBrowse link
positive regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29501879)		 UniProt
RGD		 PMID:29501879 GO_REF:0000024 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 ISO (MGI:3604916|PMID:16162653) RGD PMID:16162653 MGI:3604916 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865 		JBrowse link
regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO MGI:104564 (MGI:1309707|PMID:9784491) RGD PMID:9784491 MGI:1309707 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C ISO MGI:104565 (MGI:1309707|PMID:9784491) RGD PMID:9784491 MGI:1309707 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    developmental process 6848
      anatomical structure development 6308
        lens development in camera-type eye 94
          lens epithelial cell proliferation + 2
          lens fiber cell differentiation + 38
          lens morphogenesis in camera-type eye + 27
Path 2
Term Annotations click to browse term
  biological_process 20078
    developmental process 6848
      anatomical structure development 6308
        multicellular organism development 5783
          system development 5311
            animal organ development 4062
              sensory organ development 697
                eye development 462
                  camera-type eye development 414
                    lens development in camera-type eye 94
                      lens epithelial cell proliferation + 2
                      lens fiber cell differentiation + 38
                      lens morphogenesis in camera-type eye + 27
paths to the root