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ONTOLOGY REPORT - ANNOTATIONS

Term:glandular epithelial cell development
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Accession:GO:0002068 term browser browse the term
Definition:The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.


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glandular epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fasn fatty acid synthase acts_upstream_of_or_within IMP (PMID:25565205) MGI PMID:25565205 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Muc2 mucin 2 acts_upstream_of_or_within IMP (PMID:11872843) MGI PMID:11872843 NCBI chr 7:141,276,583...141,308,428
Ensembl chr 7:141,276,583...141,308,430 		JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within IGI (PMID:7607067) MGI PMID:7607067 NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within IGI (PMID:7607067) MGI PMID:7607067 NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924 		JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within IGI (PMID:7607067) MGI PMID:7607067 NCBI chr15:102,143,373...102,165,891
Ensembl chr15:102,143,373...102,165,952 		JBrowse link
G Slc9a4 solute carrier family 9 (sodium/hydrogen exchanger), member 4 acts_upstream_of_or_within IMP (PMID:15684419) MGI PMID:15684419 NCBI chr 1:40,619,146...40,670,188
Ensembl chr 1:40,619,241...40,669,885 		JBrowse link
G Spdef SAM pointed domain containing ets transcription factor acts_upstream_of_or_within IMP (PMID:19549527) MGI PMID:19549527 NCBI chr17:27,933,416...27,949,977
Ensembl chr17:27,933,326...27,947,929 		JBrowse link
glandular epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlha15 basic helix-loop-helix family, member a15 acts_upstream_of_or_within IMP (PMID:15024058) MGI PMID:15024058 NCBI chr 5:144,127,104...144,131,259
Ensembl chr 5:144,127,104...144,131,259 		JBrowse link
G Fzd5 frizzled class receptor 5 acts_upstream_of_or_within IMP (PMID:15778706) MGI PMID:15778706 NCBI chr 1:64,769,717...64,776,907
Ensembl chr 1:64,769,717...64,776,910 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within IMP (PMID:16543408) MGI PMID:16543408 NCBI chr 6:88,170,873...88,184,014
Ensembl chr 6:88,170,873...88,184,014 		JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 acts_upstream_of_or_within IMP (PMID:16449762) MGI PMID:16449762 NCBI chr 8:23,661,281...23,698,469
Ensembl chr 8:23,661,281...23,698,362 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit acts_upstream_of_or_within IMP (PMID:20808783) MGI PMID:20808783 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Pgr progesterone receptor acts_upstream_of_or_within IMP (PMID:14765981) MGI PMID:14765981 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Xbp1 X-box binding protein 1 acts_upstream_of_or_within IMP (PMID:16362047) MGI PMID:16362047 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr cystic fibrosis transmembrane conductance regulator involved_in ISO RGD
MGI		 PMID:23178930 GO_REF:0000096 MGI:4417868 RGD:11567224 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 involved_in IMP
ISO		 (MGI:4943812|PMID:20592023) BHF-UCL
MGI		 PMID:20592023 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 MGI:4943812 NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in IMP (MGI:3778846|PMID:18223655) UniProt PMID:18223655 MGI:3778846 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) involved_in IMP (MGI:4941444|PMID:20413507) BHF-UCL PMID:20413507 MGI:4941444 NCBI chr19:27,739,121...27,995,287
Ensembl chr19:27,739,121...27,988,566 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 involved_in IMP (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333 		JBrowse link
G Clock clock circadian regulator involved_in IMP (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639 		JBrowse link
G Rheb Ras homolog enriched in brain involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:25,007,821...25,047,359
Ensembl chr 5:25,007,821...25,047,622 		JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:75,682,647...75,807,598
Ensembl chr 9:75,682,646...75,807,592 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278 		JBrowse link
G Cdh2 cadherin 2 involved_in IMP (MGI:6216737|PMID:26750727) UniProt PMID:26750727 MGI:6216737 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303 		JBrowse link
G Cdk6 cyclin dependent kinase 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IMP (MGI:5426345|PMID:22529374) UniProt PMID:22529374 MGI:5426345 NCBI chr17:15,587,616...15,597,275
Ensembl chr17:15,587,616...15,597,134 		JBrowse link
G Insm1 insulinoma-associated 1 acts_upstream_of_or_within IMP (PMID:16951258) MGI PMID:16951258 NCBI chr 2:146,064,021...146,066,940
Ensembl chr 2:146,063,841...146,066,940 		JBrowse link
G Mir214 microRNA 214 acts_upstream_of_or_within IDA (PMID:17804764) MGI PMID:17804764 NCBI chr 1:162,050,937...162,051,046
Ensembl chr 1:162,050,937...162,051,046 		JBrowse link
G Mir375 microRNA 375 acts_upstream_of_or_within IDA (PMID:17804764) MGI PMID:17804764 NCBI chr 1:74,939,817...74,939,880
Ensembl chr 1:74,939,817...74,939,880 		JBrowse link
G Mir503 microRNA 503 acts_upstream_of_or_within IDA (PMID:17804764) MGI PMID:17804764 NCBI chr  X:52,142,861...52,142,931
Ensembl chr  X:52,142,861...52,142,931 		JBrowse link
G Mir541 microRNA 541 acts_upstream_of_or_within IDA (PMID:17804764) MGI PMID:17804764 NCBI chr12:109,708,843...109,708,932
Ensembl chr12:109,708,843...109,708,932 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within IDA
IMP		 (PMID:17456846)
(PMID:17202186)		 MGI PMID:17202186 PMID:17456846 NCBI chr 2:146,967,909...147,037,270
Ensembl chr 2:147,019,466...147,036,163 		JBrowse link
G Nkx6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chr 5:101,807,050...101,812,577
Ensembl chr 5:101,806,005...101,812,862 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in IMP (MGI:4365695|PMID:19635472) UniProt PMID:19635472 MGI:4365695 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 acts_upstream_of_or_within IMP (PMID:23776622) MGI PMID:23776622 NCBI chr 9:45,849,155...45,869,299
Ensembl chr 9:45,849,155...45,866,556 		JBrowse link
G Smo smoothened, frizzled class receptor acts_upstream_of_or_within IMP (PMID:20185815) MGI PMID:20185815 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364 		JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A acts_upstream_of_or_within IMP (PMID:16246260) MGI PMID:16246260 NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlha15 basic helix-loop-helix family, member a15 acts_upstream_of_or_within IMP (PMID:16423820) MGI PMID:16423820 NCBI chr 5:144,127,104...144,131,259
Ensembl chr 5:144,127,104...144,131,259 		JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within IMP (PMID:15548585) MGI PMID:15548585 NCBI chr10:128,716,393...128,727,587
Ensembl chr10:128,718,164...128,727,587 		JBrowse link
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) involved_in IMP (MGI:4941444|PMID:20413507) BHF-UCL PMID:20413507 MGI:4941444 NCBI chr19:27,739,121...27,995,287
Ensembl chr19:27,739,121...27,988,566 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28697
    cellular process 17623
      cellular developmental process 5083
        cell development 3463
          epithelial cell development 267
            columnar/cuboidal epithelial cell development 64
              glandular epithelial cell development 39
                glandular epithelial cell maturation + 9
                pancreatic A cell development 1
                pancreatic D cell development 0
                pancreatic E cell development 0
                pancreatic PP cell development 0
                thyroid-stimulating hormone-secreting cell development 0
                type B pancreatic cell development + 25
Path 2
Term Annotations click to browse term
  biological_process 28697
    developmental process 7399
      anatomical structure development 6868
        tissue development 2366
          epithelium development 1461
            epithelial cell differentiation 867
              columnar/cuboidal epithelial cell differentiation 155
                glandular epithelial cell differentiation 84
                  glandular epithelial cell development 39
                    glandular epithelial cell maturation + 9
                    pancreatic A cell development 1
                    pancreatic D cell development 0
                    pancreatic E cell development 0
                    pancreatic PP cell development 0
                    thyroid-stimulating hormone-secreting cell development 0
                    type B pancreatic cell development + 25
paths to the root