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ONTOLOGY REPORT - ANNOTATIONS

Term:glandular epithelial cell development
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Accession:GO:0002068 term browser browse the term
Definition:The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.


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glandular epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FASN fatty acid synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25565205) Ensembl
MGI		 PMID:25565205 GO_REF:0000107 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming acts_upstream_of_or_within ISO (PMID:11872843) MGI PMID:11872843 NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G RARA retinoic acid receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643 		JBrowse link
G RARB retinoic acid receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932 		JBrowse link
G RARG retinoic acid receptor gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr12:53,210,569...53,232,209
Ensembl chr12:53,210,567...53,232,980 		JBrowse link
G SLC9A4 solute carrier family 9 member A4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15684419) Ensembl
MGI		 PMID:15684419 GO_REF:0000107 NCBI chr 2:102,473,226...102,533,972
Ensembl chr 2:102,473,226...102,533,972 		JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19549527) Ensembl
MGI		 PMID:19549527 GO_REF:0000107 NCBI chr 6:34,537,802...34,556,329
Ensembl chr 6:34,537,802...34,556,333 		JBrowse link
glandular epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15024058) Ensembl
MGI		 PMID:15024058 GO_REF:0000107 NCBI chr 7:98,211,439...98,215,457
Ensembl chr 7:98,211,439...98,215,457 		JBrowse link
G FZD5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15778706) Ensembl
MGI		 PMID:15778706 GO_REF:0000107 NCBI chr 2:207,762,598...207,769,906
Ensembl chr 2:207,762,598...207,769,906 		JBrowse link
G GATA2 GATA binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16543408) Ensembl
MGI		 PMID:16543408 GO_REF:0000107 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G GPAT4 glycerol-3-phosphate acyltransferase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16449762) Ensembl
MGI		 PMID:16449762 GO_REF:0000107 NCBI chr 8:41,578,200...41,625,001
Ensembl chr 8:41,577,187...41,625,001 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20808783) Ensembl
MGI		 PMID:20808783 GO_REF:0000107 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G PGR progesterone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14765981) Ensembl
MGI		 PMID:14765981 GO_REF:0000107 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (PMID:16362047) MGI PMID:16362047 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in TAS (PMID:19366350) UniProt PMID:19366350 NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in TAS (PMID:19366350) UniProt PMID:19366350 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in IMP
IEA		 (PMID:20592023) BHF-UCL
Ensembl		 PMID:20592023 GO_REF:0000107 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G NKX6-1 NK6 homeobox 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA
ISS		 (PMID:20413507) Ensembl
BHF-UCL		 PMID:20413507 GO_REF:0000107 NCBI chr 9:3,218,297...3,526,001
Ensembl chr 9:3,218,297...3,526,004 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in TAS Reactome Reactome:R-HSA-211163 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G BMAL1 basic helix-loop-helix ARNT like 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266 		JBrowse link
G CLOCK clock circadian regulator involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:55,427,903...55,546,909
Ensembl chr 4:55,427,903...55,546,909 		JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in IMP (PMID:19258434) CACAO PMID:19258434 NCBI chr 7:151,466,012...151,519,895
Ensembl chr 7:151,466,012...151,520,120 		JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IDA (PMID:11865031) BHF-UCL PMID:11865031 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IDA (PMID:11865031) BHF-UCL PMID:11865031 NCBI chr 6:55,753,653...55,875,590
Ensembl chr 6:55,753,653...55,875,590 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IDA (PMID:11865031) BHF-UCL PMID:11865031 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G CDH2 cadherin 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CDK6 cyclin dependent kinase 6 involved_in IDA (PMID:20668294) UniProt PMID:20668294 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:170,282,206...170,291,078
Ensembl chr 6:170,282,206...170,306,565 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16951258) Ensembl
MGI		 PMID:16951258 GO_REF:0000107 NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949 		JBrowse link
G MIR214 microRNA 214 acts_upstream_of_or_within ISO (PMID:17804764) MGI PMID:17804764 NCBI chr 1:172,138,798...172,138,907
Ensembl chr 1:172,138,798...172,138,907 		JBrowse link
G MIR375 microRNA 375 acts_upstream_of_or_within ISO (PMID:17804764) MGI PMID:17804764 NCBI chr 2:219,001,645...219,001,708
Ensembl chr 2:219,001,645...219,001,708 		JBrowse link
G MIR503 microRNA 503 acts_upstream_of_or_within ISO (PMID:17804764) MGI PMID:17804764 NCBI chr  X:134,546,328...134,546,398
Ensembl chr  X:134,546,328...134,546,398 		JBrowse link
G MIR541 microRNA 541 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17804764) RNAcentral
MGI		 PMID:17804764 GO_REF:0000115 NCBI chr14:101,064,495...101,064,578
Ensembl chr14:101,064,495...101,064,578 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17456846)
(PMID:17202186)		 Ensembl
MGI		 PMID:17202186 PMID:17456846 GO_REF:0000107 NCBI chr20:21,511,017...21,522,689
Ensembl chr20:21,511,017...21,514,064 		JBrowse link
G NKX6-1 NK6 homeobox 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9603781 GO_REF:0000107 RGD:2326025 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,188 		JBrowse link
G SIDT2 SID1 transmembrane family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23776622) Ensembl
MGI		 PMID:23776622 GO_REF:0000107 NCBI chr11:117,178,743...117,197,442
Ensembl chr11:117,178,736...117,197,445 		JBrowse link
G SMO smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20185815) Ensembl
MGI		 PMID:20185815 GO_REF:0000107 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16246260) Ensembl
MGI		 PMID:16246260 GO_REF:0000107 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16423820) Ensembl
MGI		 PMID:16423820 GO_REF:0000107 NCBI chr 7:98,211,439...98,215,457
Ensembl chr 7:98,211,439...98,215,457 		JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15548585) Ensembl
MGI		 PMID:15548585 GO_REF:0000107 NCBI chr12:55,743,122...55,757,264
Ensembl chr12:55,743,122...55,757,264 		JBrowse link
G NKX6-1 NK6 homeobox 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,218,297...3,526,001
Ensembl chr 9:3,218,297...3,526,004 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19777
    cellular process 18349
      cellular developmental process 5187
        cell development 3452
          epithelial cell development 277
            columnar/cuboidal epithelial cell development 68
              glandular epithelial cell development 42
                glandular epithelial cell maturation + 10
                pancreatic A cell development 1
                pancreatic D cell development 0
                pancreatic E cell development 0
                pancreatic PP cell development 0
                thyroid-stimulating hormone-secreting cell development 0
                type B pancreatic cell development + 28
Path 2
Term Annotations click to browse term
  biological_process 19777
    developmental process 7627
      anatomical structure development 7040
        tissue development 2486
          epithelium development 1497
            epithelial cell differentiation 903
              columnar/cuboidal epithelial cell differentiation 164
                glandular epithelial cell differentiation 87
                  glandular epithelial cell development 42
                    glandular epithelial cell maturation + 10
                    pancreatic A cell development 1
                    pancreatic D cell development 0
                    pancreatic E cell development 0
                    pancreatic PP cell development 0
                    thyroid-stimulating hormone-secreting cell development 0
                    type B pancreatic cell development + 28
paths to the root