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ONTOLOGY REPORT - ANNOTATIONS


Term:glandular epithelial cell development
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Accession:GO:0002068 term browser browse the term
Definition:The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.


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glandular epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FASN fatty acid synthase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25565205) Ensembl
MGI
PMID:25565205 GO_REF:0000107 NCBI chr16:73,988,410...74,008,374
Ensembl chr16:73,982,899...74,006,551
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming acts_upstream_of_or_within ISO (PMID:11872843) MGI PMID:11872843 NCBI chr 1:893,554...926,854 JBrowse link
G RARA retinoic acid receptor alpha acts_upstream_of_or_within ISO (PMID:7607067) MGI PMID:7607067 NCBI chr16:65,817,849...65,866,862
Ensembl chr16:65,817,757...65,866,878
JBrowse link
G RARB retinoic acid receptor beta acts_upstream_of_or_within ISO (PMID:7607067) MGI PMID:7607067 NCBI chr15:69,851,447...70,266,215
Ensembl chr15:70,096,117...70,264,905
JBrowse link
G RARG retinoic acid receptor gamma acts_upstream_of_or_within ISO (PMID:7607067) MGI PMID:7607067 NCBI chr11:49,319,104...49,340,725
Ensembl chr11:49,319,839...49,328,656
JBrowse link
G SLC9A4 solute carrier family 9 member A4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15684419) Ensembl
MGI
PMID:15684419 GO_REF:0000107 NCBI chr14:6,136,179...6,197,632
Ensembl chr14:6,137,368...6,195,786
JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19549527) Ensembl
MGI
PMID:19549527 GO_REF:0000107 NCBI chr17:37,555,797...37,562,522
Ensembl chr17:37,555,820...37,562,036
JBrowse link
glandular epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15024058) Ensembl
MGI
PMID:15024058 GO_REF:0000107 NCBI chr28:14,953,483...14,957,674
Ensembl chr28:14,956,095...14,956,679
JBrowse link
G FZD5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15778706) Ensembl
MGI
PMID:15778706 GO_REF:0000107 NCBI chr10:93,545,792...93,553,092
Ensembl chr10:93,550,189...93,551,946
JBrowse link
G GATA2 GATA binding protein 2 acts_upstream_of_or_within ISO (PMID:16543408) MGI PMID:16543408 NCBI chr22:52,549,112...52,562,911
Ensembl chr22:52,555,738...52,562,909
JBrowse link
G GPAT4 glycerol-3-phosphate acyltransferase 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16449762) Ensembl
MGI
PMID:16449762 GO_REF:0000107 NCBI chr 8:39,557,262...39,598,544
Ensembl chr 8:39,557,275...39,601,567
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20808783) Ensembl
MGI
PMID:20808783 GO_REF:0000107 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288
JBrowse link
G PGR progesterone receptor acts_upstream_of_or_within ISO (PMID:14765981) MGI PMID:14765981 NCBI chr 1:92,420,970...92,519,128
Ensembl chr 1:92,430,453...92,517,296
JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (PMID:16362047) MGI PMID:16362047 NCBI chr19:11,670,605...11,677,168 JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chr21:86,154,313...86,332,436 JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in ISO (MGI:4943812|PMID:20592023)
(PMID:20592023)
BHF-UCL PMID:20592023 MGI:4943812 RGD:8552352 NCBI chr 1:33,386,165...33,414,605
Ensembl chr 1:33,392,970...33,414,587
JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in ISO (MGI:3778846|PMID:18223655) UniProt PMID:18223655 MGI:3778846 NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432
JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:76,039,729...76,344,936
Ensembl chr12:76,096,465...76,338,204
JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMAL1 basic helix-loop-helix ARNT like 1 involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr 1:51,430,670...51,540,344
Ensembl chr 1:51,431,180...51,462,674
JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:13,015,198...13,134,741
Ensembl chr 7:13,051,454...13,127,240
JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:119,652,692...119,704,833
Ensembl chr21:119,652,127...119,703,458
JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in ISO (PMID:11865031) BHF-UCL PMID:11865031 NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,696,379...15,819,454
Ensembl chr17:15,696,580...15,819,564
JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in ISO (PMID:11865031) BHF-UCL PMID:11865031 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382
JBrowse link
G CDH2 cadherin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,426,381...52,652,986
Ensembl chr18:52,426,077...52,654,828
JBrowse link
G CDK6 cyclin dependent kinase 6 involved_in ISO (PMID:20668294) UniProt PMID:20668294 NCBI chr21:56,167,731...56,403,976
Ensembl chr21:56,170,450...56,393,808
JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5426345|PMID:22529374) UniProt PMID:22529374 MGI:5426345 NCBI chr13:97,928,480...97,936,594
Ensembl chr13:97,928,634...97,936,589
JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16951258) Ensembl
MGI
PMID:16951258 GO_REF:0000107 NCBI chr 2:49,360,307...49,363,136
Ensembl chr 2:49,360,448...49,361,992
JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17456846)
(PMID:17202186)
Ensembl
MGI
PMID:17202186 PMID:17456846 GO_REF:0000107 NCBI chr 2:50,499,802...50,511,309
Ensembl chr 2:50,500,691...50,502,438
JBrowse link
G NKX6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chr 7:32,846,436...32,851,526
Ensembl chr 7:32,846,528...32,851,447
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:4365695|PMID:19635472) UniProt PMID:19635472 MGI:4365695
G SIDT2 SID1 transmembrane family member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23776622) Ensembl
MGI
PMID:23776622 GO_REF:0000107 NCBI chr 1:108,550,091...108,568,470
Ensembl chr 1:108,549,792...108,569,172
JBrowse link
G SMO smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20185815) Ensembl
MGI
PMID:20185815 GO_REF:0000107 NCBI chr21:97,788,955...97,814,549
Ensembl chr21:97,788,624...97,814,709
JBrowse link
G WNT5A Wnt family member 5A acts_upstream_of_or_within ISO (PMID:16246260) MGI PMID:16246260 NCBI chr22:16,809,454...16,836,815
Ensembl chr22:16,809,451...16,825,048
JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16423820) Ensembl
MGI
PMID:16423820 GO_REF:0000107 NCBI chr28:14,953,483...14,957,674
Ensembl chr28:14,956,095...14,956,679
JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15548585) Ensembl
MGI
PMID:15548585 GO_REF:0000107 NCBI chr11:51,693,664...51,702,781
Ensembl chr11:51,693,717...51,700,278
JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:76,039,729...76,344,936
Ensembl chr12:76,096,465...76,338,204
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17080
    cellular process 15997
      cellular developmental process 4473
        cell development 3189
          epithelial cell development 260
            columnar/cuboidal epithelial cell development 57
              glandular epithelial cell development 35
                glandular epithelial cell maturation + 9
                pancreatic A cell development 1
                pancreatic D cell development 0
                pancreatic E cell development 0
                pancreatic PP cell development 0
                thyroid-stimulating hormone-secreting cell development 0
                type B pancreatic cell development + 21
Path 2
Term Annotations click to browse term
  biological_process 17080
    developmental process 6685
      anatomical structure development 6282
        tissue development 2214
          epithelium development 1387
            epithelial cell differentiation 806
              columnar/cuboidal epithelial cell differentiation 147
                glandular epithelial cell differentiation 78
                  glandular epithelial cell development 35
                    glandular epithelial cell maturation + 9
                    pancreatic A cell development 1
                    pancreatic D cell development 0
                    pancreatic E cell development 0
                    pancreatic PP cell development 0
                    thyroid-stimulating hormone-secreting cell development 0
                    type B pancreatic cell development + 21
paths to the root