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ONTOLOGY REPORT - ANNOTATIONS

Term:glandular epithelial cell development
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Accession:GO:0002068 term browser browse the term
Definition:The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.


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glandular epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FASN fatty acid synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25565205) Ensembl
MGI		 PMID:25565205 GO_REF:0000107 NCBI chr 9:233,105...249,573
Ensembl chr 9:232,963...249,092 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming acts_upstream_of_or_within ISO (PMID:11872843) MGI PMID:11872843 NCBI chr18:45,416,347...45,438,226 JBrowse link
G RARA retinoic acid receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459 		JBrowse link
G RARB retinoic acid receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr23:18,207,253...18,931,128
Ensembl chr23:18,207,760...18,482,652 		JBrowse link
G RARG retinoic acid receptor gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr27:1,958,432...1,978,471
Ensembl chr27:1,958,204...1,978,476 		JBrowse link
G SLC9A4 solute carrier family 9 member A4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15684419) Ensembl
MGI		 PMID:15684419 GO_REF:0000107 NCBI chr10:40,492,031...40,560,423
Ensembl chr10:40,492,613...40,560,472 		JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19549527) Ensembl
MGI		 PMID:19549527 GO_REF:0000107 NCBI chr12:3,814,806...3,831,724
Ensembl chr12:3,815,300...3,831,477 		JBrowse link
glandular epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 acts_upstream_of_or_within ISO (PMID:15024058) MGI PMID:15024058 NCBI chr 6:11,112,233...11,115,776
Ensembl chr 6:11,114,694...11,115,257 		JBrowse link
G FZD5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15778706) Ensembl
MGI		 PMID:15778706 GO_REF:0000107 NCBI chr37:16,123,788...16,126,634
Ensembl chr37:16,123,798...16,125,567 		JBrowse link
G GATA2 GATA binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16543408) Ensembl
MGI		 PMID:16543408 GO_REF:0000107 NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991 		JBrowse link
G GPAT4 glycerol-3-phosphate acyltransferase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16449762) Ensembl
MGI		 PMID:16449762 GO_REF:0000107 NCBI chr16:23,990,142...24,022,822
Ensembl chr16:23,911,972...24,010,152 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20808783) Ensembl
MGI		 PMID:20808783 GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G PGR progesterone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14765981) Ensembl
MGI		 PMID:14765981 GO_REF:0000107 NCBI chr21:447,197...552,511
Ensembl chr21:447,319...552,511 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (PMID:16362047) MGI PMID:16362047 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in IEA Ensembl GO_REF:0000107
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:91,773,492...92,060,895
Ensembl chr 1:91,778,481...92,059,792 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARNTL aryl hydrocarbon receptor nuclear translocator like involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr21:36,254,235...36,323,915
Ensembl chr21:36,290,070...36,323,622 		JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:47,684,409...47,825,733
Ensembl chr13:47,691,709...47,758,784 		JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:15,439,910...15,483,489
Ensembl chr16:15,434,111...15,483,419 		JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G CDH2 cadherin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,736,760...60,950,477
Ensembl chr 7:60,736,760...60,951,034 		JBrowse link
G CDK6 cyclin dependent kinase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5426345|PMID:22529374) UniProt PMID:22529374 MGI:5426345 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348 		JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (PMID:16951258) MGI PMID:16951258 NCBI chr24:3,008,387...3,011,186 JBrowse link
G MIR214 microRNA mir-214 acts_upstream_of_or_within ISO (PMID:17804764) MGI PMID:17804764 NCBI chr 7:26,818,559...26,818,668
Ensembl chr 7:26,818,559...26,818,670 		JBrowse link
G MIR375 microRNA mir-375 acts_upstream_of_or_within ISO (PMID:17804764) MGI PMID:17804764 NCBI chr37:25,568,052...25,568,121
Ensembl chr37:25,568,052...25,568,127 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17456846)
(PMID:17202186)		 Ensembl
MGI		 PMID:17202186 PMID:17456846 GO_REF:0000107 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874 		JBrowse link
G NKX6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chr32:8,256,513...8,263,238
Ensembl chr32:8,256,254...8,262,004 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G SIDT2 SID1 transmembrane family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23776622) Ensembl
MGI		 PMID:23776622 GO_REF:0000107 NCBI chr 5:16,397,532...16,410,827
Ensembl chr 5:16,398,815...16,411,268 		JBrowse link
G SMO smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20185815) Ensembl
MGI		 PMID:20185815 GO_REF:0000107 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16246260) Ensembl
MGI		 PMID:16246260 GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 acts_upstream_of_or_within ISO (PMID:16423820) MGI PMID:16423820 NCBI chr 6:11,112,233...11,115,776
Ensembl chr 6:11,114,694...11,115,257 		JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15548585) Ensembl
MGI		 PMID:15548585 GO_REF:0000107 NCBI chr10:142,039...152,537
Ensembl chr10:145,036...148,373 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:91,773,492...92,060,895
Ensembl chr 1:91,778,481...92,059,792 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17068
    cellular process 15927
      cellular developmental process 4357
        cell development 3123
          epithelial cell development 265
            columnar/cuboidal epithelial cell development 62
              glandular epithelial cell development 37
                glandular epithelial cell maturation + 9
                pancreatic A cell development 1
                pancreatic D cell development 0
                pancreatic E cell development 0
                pancreatic PP cell development 0
                thyroid-stimulating hormone-secreting cell development 0
                type B pancreatic cell development + 23
Path 2
Term Annotations click to browse term
  biological_process 17068
    developmental process 6529
      anatomical structure development 6154
        tissue development 2177
          epithelium development 1356
            epithelial cell differentiation 772
              columnar/cuboidal epithelial cell differentiation 153
                glandular epithelial cell differentiation 80
                  glandular epithelial cell development 37
                    glandular epithelial cell maturation + 9
                    pancreatic A cell development 1
                    pancreatic D cell development 0
                    pancreatic E cell development 0
                    pancreatic PP cell development 0
                    thyroid-stimulating hormone-secreting cell development 0
                    type B pancreatic cell development + 23
paths to the root