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ONTOLOGY REPORT - ANNOTATIONS

Term:glandular epithelial cell development
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Accession:GO:0002068 term browser browse the term
Definition:The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.

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glandular epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fasn fatty acid synthase acts_upstream_of_or_within ISO (PMID:25565205) MGI PMID:25565205 NCBI chrNW_004955506:1,063,002...1,079,939
Ensembl chrNW_004955506:1,063,002...1,079,939 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming acts_upstream_of_or_within ISO (PMID:11872843) MGI PMID:11872843 NCBI chrNW_004955476:11,108,826...11,135,697
Ensembl chrNW_004955476:11,108,826...11,135,697 		JBrowse link
G Rara retinoic acid receptor alpha acts_upstream_of_or_within ISO (PMID:7607067) MGI PMID:7607067 NCBI chrNW_004955451:14,876,663...14,917,134
Ensembl chrNW_004955451:14,897,726...14,917,134 		JBrowse link
G Rarb retinoic acid receptor beta acts_upstream_of_or_within ISO (PMID:7607067) MGI PMID:7607067 NCBI chrNW_004955430:17,067,536...17,457,558
Ensembl chrNW_004955430:17,295,174...17,460,045 		JBrowse link
G Rarg retinoic acid receptor gamma acts_upstream_of_or_within ISO (PMID:7607067) MGI PMID:7607067 NCBI chrNW_004955458:480,257...501,172
Ensembl chrNW_004955458:480,070...501,356 		JBrowse link
G Slc9a4 solute carrier family 9 member A4 acts_upstream_of_or_within ISO (PMID:15684419) MGI PMID:15684419 NCBI chrNW_004955470:7,936,677...7,989,946
Ensembl chrNW_004955470:7,936,532...7,984,777 		JBrowse link
G Spdef SAM pointed domain containing ETS transcription factor acts_upstream_of_or_within ISO (PMID:19549527) MGI PMID:19549527 NCBI chrNW_004955437:2,667,499...2,679,940
Ensembl chrNW_004955437:2,666,105...2,680,061 		JBrowse link
glandular epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlha15 basic helix-loop-helix family member a15 acts_upstream_of_or_within ISO (PMID:15024058) MGI PMID:15024058 NCBI chrNW_004955460:14,103,053...14,106,714
Ensembl chrNW_004955460:14,103,053...14,106,714 		JBrowse link
G Fzd5 frizzled class receptor 5 acts_upstream_of_or_within ISO (PMID:15778706) MGI PMID:15778706 NCBI chrNW_004955457:7,282,403...7,288,918
Ensembl chrNW_004955457:7,282,403...7,288,918 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO (PMID:16543408) MGI PMID:16543408 NCBI chrNW_004955429:15,326,551...15,334,774
Ensembl chrNW_004955429:15,327,113...15,336,460 		JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 acts_upstream_of_or_within ISO (PMID:16449762) MGI PMID:16449762 NCBI chrNW_004955536:1,266,920...1,313,765
Ensembl chrNW_004955536:1,265,409...1,313,326 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within ISO (PMID:20808783) MGI PMID:20808783 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Pgr progesterone receptor acts_upstream_of_or_within ISO (PMID:14765981) MGI PMID:14765981 NCBI chrNW_004955412:4,643,839...4,693,478 JBrowse link
G Xbp1 X-box binding protein 1 acts_upstream_of_or_within ISO (PMID:16362047) MGI PMID:16362047 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chrNW_004955432:23,179,645...23,328,347
Ensembl chrNW_004955432:23,178,866...23,328,382 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 involved_in ISO (PMID:20592023)
(MGI:4943812|PMID:20592023)		 BHF-UCL PMID:20592023 MGI:4943812 RGD:8552352 NCBI chrNW_004955476:10,058,979...10,074,668
Ensembl chrNW_004955476:10,058,961...10,074,162 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2 associated agonist of cell death involved_in ISO (MGI:3778846|PMID:18223655) UniProt PMID:18223655 MGI:3778846 NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (MGI:4941444|PMID:20413507) BHF-UCL PMID:20413507 MGI:4941444 NCBI chrNW_004955434:7,635,363...7,910,056
Ensembl chrNW_004955434:7,610,422...7,881,304 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chrNW_004955414:28,652,663...28,748,360
Ensembl chrNW_004955414:28,684,226...28,748,360 		JBrowse link
G Clock clock circadian regulator involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chrNW_004955447:15,394,496...15,537,969
Ensembl chrNW_004955447:15,454,630...15,530,906 		JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in ISO (PMID:19258434) CACAO PMID:19258434 NCBI chrNW_004955491:5,795,040...5,833,897
Ensembl chrNW_004955491:5,794,911...5,834,912 		JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:11865031) BHF-UCL PMID:11865031 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:11865031) BHF-UCL PMID:11865031 NCBI chrNW_004955411:450,674...557,213
Ensembl chrNW_004955411:450,674...558,650 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:11865031) BHF-UCL PMID:11865031 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377 		JBrowse link
G Cdh2 cadherin 2 involved_in ISO (MGI:6216737|PMID:26750727) UniProt PMID:26750727 MGI:6216737 NCBI chrNW_004955402:15,829,895...16,049,874
Ensembl chrNW_004955402:15,831,110...16,049,890 		JBrowse link
G Cdk6 cyclin dependent kinase 6 involved_in ISO (PMID:20668294) UniProt PMID:20668294 NCBI chrNW_004955432:9,521,794...9,727,772
Ensembl chrNW_004955432:9,521,794...9,726,417 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5426345|PMID:22529374) UniProt PMID:22529374 MGI:5426345 NCBI chrNW_004955411:3,478,943...3,486,541
Ensembl chrNW_004955411:3,478,033...3,486,604 		JBrowse link
G Insm1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (PMID:16951258) MGI PMID:16951258 NCBI chrNW_004955415:28,396,176...28,398,114 JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (PMID:17456846)
(PMID:17202186)		 MGI PMID:17202186 PMID:17456846 NCBI chrNW_004955415:29,263,741...29,268,259
Ensembl chrNW_004955415:29,258,434...29,268,259 		JBrowse link
G Nkx6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chrNW_004955474:5,211,281...5,214,785 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:4365695|PMID:19635472) UniProt PMID:19635472 MGI:4365695 NCBI chrNW_004955442:14,685,089...14,772,870
Ensembl chrNW_004955442:14,685,153...14,772,870 		JBrowse link
G Sidt2 SID1 transmembrane family member 2 acts_upstream_of_or_within ISO (PMID:23776622) MGI PMID:23776622 NCBI chrNW_004955412:18,505,453...18,521,667
Ensembl chrNW_004955412:18,505,453...18,522,082 		JBrowse link
G Smo smoothened, frizzled class receptor acts_upstream_of_or_within ISO (PMID:20185815) MGI PMID:20185815 NCBI chrNW_004955479:9,963,377...9,991,670
Ensembl chrNW_004955479:9,964,170...9,993,165 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO (PMID:16246260) MGI PMID:16246260 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlha15 basic helix-loop-helix family member a15 acts_upstream_of_or_within ISO (PMID:16423820) MGI PMID:16423820 NCBI chrNW_004955460:14,103,053...14,106,714
Ensembl chrNW_004955460:14,103,053...14,106,714 		JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within ISO (PMID:15548585) MGI PMID:15548585 NCBI chrNW_004955458:3,388,402...3,398,040
Ensembl chrNW_004955458:3,388,402...3,398,040 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (MGI:4941444|PMID:20413507) BHF-UCL PMID:20413507 MGI:4941444 NCBI chrNW_004955434:7,635,363...7,910,056
Ensembl chrNW_004955434:7,610,422...7,881,304 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12482
    cellular process 11573
      cellular developmental process 3901
        cell development 2854
          epithelial cell development 248
            columnar/cuboidal epithelial cell development 57
              glandular epithelial cell development 35
                glandular epithelial cell maturation + 9
                pancreatic A cell development 1
                pancreatic D cell development 0
                pancreatic E cell development 0
                pancreatic PP cell development 0
                thyroid-stimulating hormone-secreting cell development 0
                type B pancreatic cell development + 21
Path 2
Term Annotations click to browse term
  biological_process 12482
    developmental process 5885
      anatomical structure development 5569
        tissue development 1981
          epithelium development 1238
            epithelial cell differentiation 696
              columnar/cuboidal epithelial cell differentiation 143
                glandular epithelial cell differentiation 75
                  glandular epithelial cell development 35
                    glandular epithelial cell maturation + 9
                    pancreatic A cell development 1
                    pancreatic D cell development 0
                    pancreatic E cell development 0
                    pancreatic PP cell development 0
                    thyroid-stimulating hormone-secreting cell development 0
                    type B pancreatic cell development + 21
paths to the root