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ONTOLOGY REPORT - ANNOTATIONS

Term:glandular epithelial cell development
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Accession:GO:0002068 term browser browse the term
Definition:The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.


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glandular epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FASN fatty acid synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25565205) Ensembl
MGI		 PMID:25565205 GO_REF:0000107 NCBI chr17:76,483,108...76,503,148
Ensembl chr17:82,187,516...82,205,647 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming acts_upstream_of_or_within ISO (PMID:11872843) MGI PMID:11872843 NCBI chr11:1,106,716...1,144,489
Ensembl chr11:1,143,625...1,169,741 		JBrowse link
G RARA retinoic acid receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr17:16,932,485...16,980,958 JBrowse link
G RARB retinoic acid receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr 3:24,729,220...25,499,187
Ensembl chr 3:25,660,922...25,833,297 		JBrowse link
G RARG retinoic acid receptor gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7607067) Ensembl
MGI		 PMID:7607067 GO_REF:0000107 NCBI chr12:35,521,276...35,542,814
Ensembl chr12:36,303,359...36,325,111 		JBrowse link
G SLC9A4 solute carrier family 9 member A4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15684419) Ensembl
MGI		 PMID:15684419 GO_REF:0000107 NCBI chr2A:99,280,738...99,341,618
Ensembl chr2A:103,566,128...103,626,975 		JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19549527) Ensembl
MGI		 PMID:19549527 GO_REF:0000107 Ensembl chr 6:35,202,983...35,209,639 JBrowse link
glandular epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15024058) Ensembl
MGI		 PMID:15024058 GO_REF:0000107 NCBI chr 7:6,306,929...6,311,026
Ensembl chr 7:103,677,022...103,677,593 		JBrowse link
G FZD5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15778706) Ensembl
MGI		 PMID:15778706 GO_REF:0000107 NCBI chr2B:95,003,246...95,010,577
Ensembl chr2B:213,133,017...213,134,774 		JBrowse link
G GATA2 GATA binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16543408) Ensembl
MGI		 PMID:16543408 GO_REF:0000107 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035 		JBrowse link
G GPAT4 glycerol-3-phosphate acyltransferase 4 acts_upstream_of_or_within ISO (PMID:16449762) MGI PMID:16449762 NCBI chr 8:40,822,736...40,869,744
Ensembl chr 8:38,271,808...38,318,587 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20808783) Ensembl
MGI		 PMID:20808783 GO_REF:0000107 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G PGR progesterone receptor acts_upstream_of_or_within ISO (PMID:14765981) MGI PMID:14765981 NCBI chr11:95,997,677...96,098,866 JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (PMID:16362047) MGI PMID:16362047 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMAL1 basic helix-loop-helix ARNT like 1 involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr11:13,436,580...13,547,135
Ensembl chr11:13,163,028...13,240,376 		JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,391,310...68,509,813
Ensembl chr 4:75,018,898...75,066,726 		JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in ISO (PMID:19258434) CACAO PMID:19258434 NCBI chr 7:143,054,747...143,108,011 JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G CDH2 cadherin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:21,210,001...21,435,919
Ensembl chr18:24,812,019...25,008,325 		JBrowse link
G CDK6 cyclin dependent kinase 6 involved_in ISO (PMID:20668294) UniProt PMID:20668294 NCBI chr 7:84,603,419...84,835,082 JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (PMID:16951258) MGI PMID:16951258 NCBI chr20:20,317,060...20,320,051 JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17456846)
(PMID:17202186)		 Ensembl
MGI		 PMID:17202186 PMID:17456846 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G NKX6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:4365695|PMID:19635472) UniProt PMID:19635472 MGI:4365695 NCBI chr16:1,394,447...1,463,735 JBrowse link
G SIDT2 SID1 transmembrane family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23776622) Ensembl
MGI		 PMID:23776622 GO_REF:0000107 NCBI chr11:112,012,734...112,031,403
Ensembl chr11:115,946,725...115,963,408 		JBrowse link
G SMO smoothened, frizzled class receptor acts_upstream_of_or_within ISO (PMID:20185815) MGI PMID:20185815 NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16246260) Ensembl
MGI		 PMID:16246260 GO_REF:0000107 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16423820) Ensembl
MGI		 PMID:16423820 GO_REF:0000107 NCBI chr 7:6,306,929...6,311,026
Ensembl chr 7:103,677,022...103,677,593 		JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15548585) Ensembl
MGI		 PMID:15548585 GO_REF:0000107 NCBI chr12:33,154,530...33,168,427
Ensembl chr12:33,879,180...33,893,252 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16768
    cellular process 15760
      cellular developmental process 4436
        cell development 3161
          epithelial cell development 257
            columnar/cuboidal epithelial cell development 58
              glandular epithelial cell development 35
                glandular epithelial cell maturation + 9
                pancreatic A cell development 1
                pancreatic D cell development 0
                pancreatic E cell development 0
                pancreatic PP cell development 0
                thyroid-stimulating hormone-secreting cell development 0
                type B pancreatic cell development + 21
Path 2
Term Annotations click to browse term
  biological_process 16768
    developmental process 6615
      anatomical structure development 6217
        tissue development 2198
          epithelium development 1386
            epithelial cell differentiation 808
              columnar/cuboidal epithelial cell differentiation 148
                glandular epithelial cell differentiation 77
                  glandular epithelial cell development 35
                    glandular epithelial cell maturation + 9
                    pancreatic A cell development 1
                    pancreatic D cell development 0
                    pancreatic E cell development 0
                    pancreatic PP cell development 0
                    thyroid-stimulating hormone-secreting cell development 0
                    type B pancreatic cell development + 21
paths to the root