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ONTOLOGY REPORT - ANNOTATIONS


Term:columnar/cuboidal epithelial cell development
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Accession:GO:0002066 term browser browse the term
Definition:The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.


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columnar/cuboidal epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(MGI:80739|PMID:8675006)
UniProt
RGD
PMID:8675006 GO_REF:0000024 MGI:80739 NCBI chr20:33,100,190...33,323,544
Ensembl chr20:33,100,191...33,323,367
JBrowse link
G Shroom3 shroom family member 3 acts_upstream_of_or_within ISO (MGI:3610718|PMID:16249236) RGD PMID:16249236 MGI:3610718 NCBI chr14:16,622,767...16,903,265
Ensembl chr14:16,622,760...16,903,242
JBrowse link
columnar/cuboidal epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO (MGI:6443509|PMID:31336344) RGD PMID:31336344 MGI:6443509 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
glandular epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fasn fatty acid synthase acts_upstream_of_or_within ISO MGI:3765070 (MGI:5630041|PMID:25565205) RGD PMID:25565205 MGI:5630041 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within ISO MGI:97858 (MGI:69060|PMID:7607067) RGD PMID:7607067 MGI:69060 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO MGI:97858 (MGI:69060|PMID:7607067) RGD PMID:7607067 MGI:69060 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within ISO MGI:97856|MGI:97857 (MGI:69060|PMID:7607067) RGD PMID:7607067 MGI:69060 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
glandular epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpat4 glycerol-3-phosphate acyltransferase 4 acts_upstream_of_or_within ISO MGI:3624276 (MGI:3623167|PMID:16449762) RGD PMID:16449762 MGI:3623167 NCBI chr16:73,615,949...73,649,769
Ensembl chr16:73,615,949...73,649,767
JBrowse link
intestinal epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3714051 (MGI:5002772|PMID:21383503)
Ensembl
RGD
PMID:21383503 GO_REF:0000107 MGI:5002772 NCBI chr 4:33,890,353...33,943,219
Ensembl chr 4:33,890,349...33,943,211
JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (MGI:5449145|PMID:22766025) RGD PMID:22766025 MGI:5449145 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:108015 (MGI:4946569|PMID:21307095) RGD PMID:21307095 MGI:4946569 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in IEA
ISO
GO_REF:0000107
(MGI:5629863|PMID:25731159)
(PMID:25731159)
Ensembl
RGD
PMID:25731159 GO_REF:0000107 MGI:5629863 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Klf5 Kruppel-like factor 5 acts_upstream_of_or_within ISO MGI:3806635 (MGI:5471906|PMID:23266329) RGD PMID:23266329 MGI:5471906 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Mir3545 microRNA 3545 acts_upstream_of_or_within ISO (MGI:4946569|PMID:21307095) RGD PMID:21307095 MGI:4946569 NCBI chr 6:136,704,947...136,705,061
Ensembl chr 6:136,704,947...136,705,061
JBrowse link
G Mir7-1 microRNA 7-1 acts_upstream_of_or_within ISO (MGI:4946569|PMID:21307095) RGD PMID:21307095 MGI:4946569 NCBI chr17:6,675,016...6,675,112
Ensembl chr17:6,675,016...6,675,112
JBrowse link
G Nkx3-2 NK3 homeobox 2 acts_upstream_of_or_within ISO MGI:2177178 (MGI:4946569|PMID:21307095) RGD PMID:21307095 MGI:4946569 NCBI chr14:73,813,531...73,818,489
Ensembl chr14:73,813,528...73,815,757
JBrowse link
G Prdm1 PR/SET domain 1 acts_upstream_of_or_within ISO MGI:3605483|MGI:3605621 (MGI:5014435|PMID:21670299) RGD PMID:21670299 MGI:5014435 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Spdef SAM pointed domain containing ets transcription factor acts_upstream_of_or_within ISO MGI:4410321 (MGI:4410300|PMID:19549527) RGD PMID:19549527 MGI:4410300 NCBI chr20:7,292,823...7,308,053
Ensembl chr20:7,292,824...7,307,284
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:25731159)
(MGI:5629863|PMID:25731159)
RGD PMID:25731159 MGI:5629863 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO MGI:4391656 (MGI:5498602|PMID:23726973) RGD PMID:23726973 MGI:5498602 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in ISO (PMID:25731159)
(MGI:5629863|PMID:25731159)
RGD PMID:25731159 MGI:5629863 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Yipf6 Yip1 domain family, member 6 acts_upstream_of_or_within ISO MGI:4839074 (MGI:5437477|PMID:22802641) RGD PMID:22802641 MGI:5437477 NCBI chr  X:68,625,760...68,637,780
Ensembl chr  X:68,626,185...68,637,416
JBrowse link
intestinal epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:20466941 RGD:8662316 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2384429 (MGI:4830408|PMID:20808783)
Ensembl
RGD
PMID:20808783 GO_REF:0000107 MGI:4830408 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hoxa5 homeo box A5 acts_upstream_of_or_within ISO MGI:2150397 (MGI:1349338|PMID:10564089) RGD PMID:10564089 MGI:1349338 NCBI chr 4:82,170,383...82,174,788
Ensembl chr 4:82,170,387...82,173,207
JBrowse link
G Tyms thymidylate synthetase IEP RGD PMID:1260861 RGD:2317427 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IMP RGD PMID:23178930 RGD:11567224 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 involved_in IMP
IEA
ISO
PMID:20592023
GO_REF:0000107
(MGI:4943812|PMID:20592023)
(PMID:20592023)
Ensembl
RGD
PMID:20592023, PMID:20592023 GO_REF:0000107 MGI:4943812, RGD:8552352 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISS
ISO
GO_REF:0000024
(MGI:3778846|PMID:18223655)
UniProt
RGD
PMID:18223655 GO_REF:0000024 MGI:3778846 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (MGI:4941444|PMID:20413507) RGD PMID:20413507 MGI:4941444 NCBI chr 1:245,853,332...246,110,648
Ensembl chr 1:245,859,633...246,110,218
JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arntl aryl hydrocarbon receptor nuclear translocator-like involved_in ISS
ISO
GO_REF:0000024
(MGI:4819446|PMID:20562852)
UniProt
RGD
PMID:20562852 GO_REF:0000024 MGI:4819446 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Clock clock circadian regulator involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4819446|PMID:20562852)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20562852 GO_REF:0000024 GO_REF:0000107 MGI:4819446 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in ISO
IEA
(PMID:19258434)
GO_REF:0000107
RGD
Ensembl
PMID:19258434 GO_REF:0000107 NCBI chr 4:6,827,429...6,873,384
Ensembl chr 4:6,827,429...6,873,383
JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA
ISS
(PMID:11865031)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11865031 GO_REF:0000024 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:11865031) RGD PMID:11865031 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:11865031) RGD PMID:11865031 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Cdh2 cadherin 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:6216737|PMID:26750727)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:26750727 GO_REF:0000024 GO_REF:0000107 MGI:6216737 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:20668294) RGD PMID:20668294 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5426345|PMID:22529374)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:22529374 GO_REF:0000024 GO_REF:0000107 MGI:5426345 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Insm1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO MGI:3656035 (MGI:3655758|PMID:16951258) RGD PMID:16951258 MGI:3655758 NCBI chr 3:140,427,961...140,430,467 JBrowse link
G Mir375 microRNA 375 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) RGD PMID:17804764 MGI:3775688 NCBI chr 9:82,161,716...82,161,790
Ensembl chr 9:82,161,716...82,161,790
JBrowse link
G Mir503 microRNA 503 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) RGD PMID:17804764 MGI:3775688 NCBI chr  X:158,148,476...158,148,546
Ensembl chr  X:158,148,476...158,148,546
JBrowse link
G Mir541 microRNA 541 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) RGD PMID:17804764 MGI:3775688 NCBI chr 6:133,892,655...133,892,744
Ensembl chr 6:133,892,655...133,892,744
JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:3703458|PMID:17202186), (MGI:3761395|PMID:17456846) RGD PMID:17202186 PMID:17456846 MGI:3703458 MGI:3761395 NCBI chr 3:141,408,460...141,419,083
Ensembl chr 3:141,408,798...141,411,170
JBrowse link
G Nkx6-1 NK6 homeobox 1 IEP RGD PMID:9603781 RGD:2326025 NCBI chr14:9,555,264...9,562,197
Ensembl chr14:9,555,264...9,562,189
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (MGI:4365695|PMID:19635472) RGD PMID:19635472 MGI:4365695 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Sidt2 SID1 transmembrane family, member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5532825 (MGI:5529865|PMID:23776622)
Ensembl
RGD
PMID:23776622 GO_REF:0000107 MGI:5529865 NCBI chr 8:50,230,335...50,246,979
Ensembl chr 8:50,230,339...50,246,656
JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176256|MGI:2684317 (MGI:4833770|PMID:20185815)
Ensembl
RGD
PMID:20185815 GO_REF:0000107 MGI:4833770 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857617 (MGI:3663526|PMID:16246260)
Ensembl
RGD
PMID:16246260 GO_REF:0000107 MGI:3663526 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfx3 regulatory factor X3 involved_in ISO (MGI:4941444|PMID:20413507) RGD PMID:20413507 MGI:4941444 NCBI chr 1:245,853,332...246,110,648
Ensembl chr 1:245,859,633...246,110,218
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    developmental process 6790
      anatomical structure development 6263
        cell development 2440
          epithelial cell development 288
            columnar/cuboidal epithelial cell development 50
              columnar/cuboidal epithelial cell maturation + 7
              glandular epithelial cell development + 29
              intestinal epithelial cell development + 18
Path 2
Term Annotations click to browse term
  biological_process 19612
    developmental process 6790
      anatomical structure development 6263
        tissue development 2069
          epithelium development 1272
            epithelial cell differentiation 712
              epithelial cell development 288
                columnar/cuboidal epithelial cell development 50
                  columnar/cuboidal epithelial cell maturation + 7
                  glandular epithelial cell development + 29
                  intestinal epithelial cell development + 18
paths to the root