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ONTOLOGY REPORT - ANNOTATIONS


Term:chondrocyte development
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Accession:GO:0002063 term browser browse the term
Definition:The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.



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chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856465 (MGI:1270958|PMID:9664687)
Ensembl
RGD
PMID:9664687 GO_REF:0000107 MGI:1270958 NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:9442116) RGD PMID:9442116 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within ISO MGI:3806990 (MGI:3799383|PMID:18539921) RGD PMID:18539921 MGI:3799383 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within ISO MGI:5007063 (MGI:5316547|PMID:22280990) RGD PMID:22280990 MGI:5316547 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601
JBrowse link
G Col11a1 collagen type XI alpha 1 chain acts_upstream_of_or_within ISO MGI:1856399 (MGI:53676|PMID:4100752) RGD PMID:4100752 MGI:53676 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3758741|MGI:5550566 (MGI:3723532|PMID:17588960), (MGI:5550565|PMID:22006726)
Ensembl
RGD
PMID:17588960 PMID:22006726 GO_REF:0000107 MGI:3723532 MGI:5550565 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845
JBrowse link
G Ecm1 extracellular matrix protein 1 acts_upstream_of_or_within ISO (MGI:4452294|PMID:20138147) RGD PMID:20138147 MGI:4452294 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2183829 (MGI:2670283|PMID:12865332) RGD PMID:12865332 MGI:2670283 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2178751 (MGI:3703411|PMID:17014841)
Ensembl
RGD
PMID:17014841 GO_REF:0000107 MGI:3703411 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO MGI:5007248 (MGI:5008683|PMID:21606205) RGD PMID:21606205 MGI:5008683 NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972
JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1926381 (MGI:1355063|PMID:10742104)
Ensembl
RGD
PMID:10742104 GO_REF:0000107 MGI:1355063 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Rarg retinoic acid receptor, gamma involved_in ISO (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176466 (MGI:1334093|PMID:10213384)
Ensembl
RGD
PMID:10213384 GO_REF:0000107 MGI:1334093 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:3810257 (MGI:3806414|PMID:18729207) RGD PMID:18729207 MGI:3806414 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Shox2 short stature homeobox 2 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3605739 (MGI:3714677|PMID:17481601)
GO_REF:0000107
RGD
Ensembl
PMID:17481601 GO_REF:0000107 MGI:3714677 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO MGI:3575405 (MGI:3715574|PMID:17591962), (MGI:5582670|PMID:24505141) RGD PMID:17591962 PMID:24505141 MGI:3715574 MGI:5582670 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3784676|PMID:18415932) RGD PMID:18415932 MGI:3784676 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sulf1 sulfatase 1 involved_in IEA
ISO
ISS
GO_REF:0000104
(MGI:5306560|PMID:20479257)
GO_REF:0000024
UniProt
RGD
PMID:20479257 GO_REF:0000024 GO_REF:0000104 MGI:5306560 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584
JBrowse link
G Sulf2 sulfatase 2 involved_in ISO (MGI:5306560|PMID:20479257) RGD PMID:20479257 MGI:5306560 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
chondrocyte development involved in endochondral bone morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinh1 serpin family H member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176070|MGI:5505265 (MGI:5494537|PMID:22492985)
Ensembl
RGD
PMID:22492985 GO_REF:0000107 MGI:5494537 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856877 (MGI:5293259|PMID:21788370)
Ensembl
RGD
PMID:21788370 GO_REF:0000107 MGI:5293259 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:5528913|PMID:23958822) RGD PMID:23958822 MGI:5528913 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Mex3c mex-3 RNA binding family member C acts_upstream_of_or_within ISO MGI:3764947 (MGI:5446032|PMID:22357625) RGD PMID:22357625 MGI:5446032 NCBI chr18:67,167,600...67,188,595
Ensembl chr18:67,166,718...67,188,595
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:4950303|PMID:21367821)
UniProt
RGD
PMID:21367821 GO_REF:0000024 MGI:4950303 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
growth plate cartilage chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col27a1 collagen type XXVII alpha 1 chain acts_upstream_of_or_within ISO MGI:5315593 (MGI:5315238|PMID:22206015) RGD PMID:22206015 MGI:5315238 NCBI chr 5:76,647,302...76,765,987
Ensembl chr 5:76,647,429...76,765,174
JBrowse link
G Poc1a POC1 centriolar protein A acts_upstream_of_or_within ISO MGI:2135614 (MGI:5700251|PMID:26496357) RGD PMID:26496357 MGI:5700251 NCBI chr 8:106,922,058...106,991,678
Ensembl chr 8:106,922,978...106,991,089
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
growth plate cartilage chondrocyte growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst5 cystatin D involved_in ISO MGI:3629665 (MGI:3629269|PMID:16680148) RGD PMID:16680148 MGI:3629269 NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754
JBrowse link
G Rarg retinoic acid receptor, gamma involved_in ISO (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:5317468|PMID:22421045)
UniProt
RGD
PMID:22421045 GO_REF:0000024 MGI:5317468 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within ISO MGI:2384513 (MGI:4949016|PMID:21420963) RGD PMID:21420963 MGI:4949016 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
growth plate cartilage chondrocyte morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Matn1 matrilin 1 acts_upstream_of_or_within ISO MGI:2153042|MGI:3663272 (MGI:3655339|PMID:16877353) RGD PMID:16877353 MGI:3655339 NCBI chr 5:143,117,198...143,127,140
Ensembl chr 5:143,117,504...143,127,059
JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO (PMID:90087) RGD PMID:90087 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Rflna refilin A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1923816 (MGI:5570967|PMID:24436304)
RGD PMID:24436304 PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr12:31,633,361...31,642,317
Ensembl chr12:31,633,361...31,642,317
JBrowse link
G Rflnb refilin B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1920371 (MGI:5570967|PMID:24436304)
RGD PMID:24436304 PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976
JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(MGI:6377914|PMID:29503843)
Ensembl
RGD
PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3579503 (MGI:4818263|PMID:19623616)
Ensembl
RGD
PMID:19623616 GO_REF:0000107 MGI:4818263 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        cell development 2481
          chondrocyte development 34
            chondrocyte development involved in endochondral bone morphogenesis + 10
            chondrocyte hypertrophy + 7
            chondrocyte morphogenesis + 1
            negative regulation of chondrocyte development + 3
            positive regulation of chondrocyte development + 1
            regulation of chondrocyte development + 5
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            skeletal system development 572
              cartilage development 221
                chondrocyte differentiation 122
                  chondrocyte development 34
                    chondrocyte development involved in endochondral bone morphogenesis + 10
                    chondrocyte hypertrophy + 7
                    chondrocyte morphogenesis + 1
                    negative regulation of chondrocyte development + 3
                    positive regulation of chondrocyte development + 1
                    regulation of chondrocyte development + 5
paths to the root