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ONTOLOGY REPORT - ANNOTATIONS

Term:chondrocyte development
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Accession:GO:0002063 term browser browse the term
Definition:The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.

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chondrocyte development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan IEA
ISO		 GO_REF:0000107
MGI:1856465 (MGI:1270958|PMID:9664687)		 Ensembl
RGD		 PMID:9664687 GO_REF:0000107 MGI:1270958 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO (PMID:9442116) RGD PMID:9442116 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 ISO MGI:3806990 (MGI:3799383|PMID:18539921) RGD PMID:18539921 MGI:3799383 NCBI chr17:90,191,119...90,218,013
Ensembl chr17:90,188,043...90,218,013
Ensembl chr 5:90,188,043...90,218,013 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 ISO MGI:5007063 (MGI:5316547|PMID:22280990) RGD PMID:22280990 MGI:5316547 NCBI chr 1:127,010,587...127,071,570
Ensembl chr 1:127,010,588...127,071,570 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain ISO MGI:1856399 (MGI:53676|PMID:4100752) RGD PMID:4100752 MGI:53676 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523 		JBrowse link
G Comp cartilage oligomeric matrix protein IEA
ISO		 GO_REF:0000107
MGI:3758741|MGI:5550566 (MGI:3723532|PMID:17588960), (MGI:5550565|PMID:22006726)		 Ensembl
RGD		 PMID:17588960 PMID:22006726 GO_REF:0000107 MGI:3723532 MGI:5550565 NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070 		JBrowse link
G Ecm1 extracellular matrix protein 1 ISO (MGI:4452294|PMID:20138147) RGD PMID:20138147 MGI:4452294 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO MGI:2183829 (MGI:2670283|PMID:12865332) RGD PMID:12865332 MGI:2670283 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Fgf18 fibroblast growth factor 18 IEA
ISO		 GO_REF:0000107
MGI:2178751 (MGI:3703411|PMID:17014841)		 Ensembl
RGD		 PMID:17014841 GO_REF:0000107 MGI:3703411 NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO MGI:5007248 (MGI:5008683|PMID:21606205) RGD PMID:21606205 MGI:5008683 NCBI chr13:101,727,434...101,770,127
Ensembl chr13:101,727,935...101,761,541 		JBrowse link
G Msx2 msh homeobox 2 IEA
ISO		 GO_REF:0000107
MGI:1926381 (MGI:1355063|PMID:10742104)		 Ensembl
RGD		 PMID:10742104 GO_REF:0000107 MGI:1355063 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527 		JBrowse link
G Rarg retinoic acid receptor, gamma ISO (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186 		JBrowse link
G Runx2 RUNX family transcription factor 2 ISO
IEA		 MGI:2176466 (MGI:1334093|PMID:10213384)
GO_REF:0000107		 RGD
Ensembl		 PMID:10213384 GO_REF:0000107 MGI:1334093 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO MGI:3810257 (MGI:3806414|PMID:18729207) RGD PMID:18729207 MGI:3806414 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764 		JBrowse link
G Shox2 short stature homeobox 2 ISO MGI:3605739 (MGI:3714677|PMID:17481601) RGD PMID:17481601 MGI:3714677 NCBI chr 2:164,118,175...164,126,783
Ensembl chr 2:164,118,191...164,126,783 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO MGI:3575405 (MGI:3715574|PMID:17591962), (MGI:5582670|PMID:24505141) RGD PMID:17591962 PMID:24505141 MGI:3715574 MGI:5582670 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528 		JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (MGI:3784676|PMID:18415932) RGD PMID:18415932 MGI:3784676 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
G Sulf1 sulfatase 1 ISS
ISO
IEA		 GO_REF:0000024
(MGI:5306560|PMID:20479257)
GO_REF:0000104		 UniProt
RGD		 PMID:20479257 GO_REF:0000024 GO_REF:0000104 MGI:5306560 NCBI chr 5:5,999,520...6,186,901
Ensembl chr 5:5,999,475...6,186,329 		JBrowse link
G Sulf2 sulfatase 2 ISO (MGI:5306560|PMID:20479257) RGD PMID:20479257 MGI:5306560 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831 		JBrowse link
chondrocyte development involved in endochondral bone morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinh1 serpin family H member 1 IEA
ISO		 GO_REF:0000107
MGI:2176070|MGI:5505265 (MGI:5494537|PMID:22492985)		 Ensembl
RGD		 PMID:22492985 GO_REF:0000107 MGI:5494537 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IEA
ISO		 GO_REF:0000107
MGI:1856877 (MGI:5293259|PMID:21788370)		 Ensembl
RGD		 PMID:21788370 GO_REF:0000107 MGI:5293259 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528 		JBrowse link
chondrocyte hypertrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mex3c mex-3 RNA binding family member C ISO MGI:3764947 (MGI:5446032|PMID:22357625) RGD PMID:22357625 MGI:5446032 NCBI chr18:69,549,937...69,571,736
Ensembl chr18:69,549,937...69,571,736 		JBrowse link
G Sox9 SRY-box transcription factor 9 ISS
ISO		 GO_REF:0000024
(MGI:4950303|PMID:21367821)		 UniProt
RGD		 PMID:21367821 GO_REF:0000024 MGI:4950303 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
growth plate cartilage chondrocyte development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col27a1 collagen type XXVII alpha 1 chain ISO MGI:5315593 (MGI:5315238|PMID:22206015) RGD PMID:22206015 MGI:5315238 NCBI chr 5:79,054,004...79,172,442
Ensembl chr 5:79,055,521...79,170,765 		JBrowse link
G Poc1a POC1 centriolar protein A ISO MGI:2135614 (MGI:5700251|PMID:26496357) RGD PMID:26496357 MGI:5700251 NCBI chr 8:114,982,764...115,050,844
Ensembl chr 8:114,986,326...115,050,728 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591 		JBrowse link
growth plate cartilage chondrocyte growth term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rarg retinoic acid receptor, gamma ISO (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186 		JBrowse link
G Sox9 SRY-box transcription factor 9 ISS
ISO		 GO_REF:0000024
(MGI:5317468|PMID:22421045)		 UniProt
RGD		 PMID:22421045 GO_REF:0000024 MGI:5317468 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO MGI:2384513 (MGI:4949016|PMID:21420963) RGD PMID:21420963 MGI:4949016 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
growth plate cartilage chondrocyte morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Matn1 matrilin 1 ISO MGI:2153042|MGI:3663272 (MGI:3655339|PMID:16877353) RGD PMID:16877353 MGI:3655339 NCBI chr 5:149,077,412...149,086,957
Ensembl chr 5:149,077,412...149,086,957 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone ISO (PMID:90087) RGD PMID:90087 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Rflna refilin A ISO
IBA		 MGI:1923816 (MGI:5570967|PMID:24436304)
PMID:21873635		 RGD PMID:24436304, PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr12:37,038,732...37,047,628
Ensembl chr12:37,038,733...37,047,628 		JBrowse link
G Rflnb refilin B ISO
IBA		 MGI:1920371 (MGI:5570967|PMID:24436304)
PMID:21873635		 RGD PMID:24436304, PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr10:64,196,103...64,202,380
Ensembl chr10:64,196,127...64,202,380 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 IEA
ISO		 GO_REF:0000107
(MGI:6377914|PMID:29503843)		 Ensembl
RGD		 PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157 		JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 IEA
ISO		 GO_REF:0000107
MGI:3579503 (MGI:4818263|PMID:19623616)		 Ensembl
RGD		 PMID:19623616 GO_REF:0000107 MGI:4818263 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20045
    developmental process 6824
      anatomical structure development 6290
        cell development 2447
          chondrocyte development 32
            chondrocyte development involved in endochondral bone morphogenesis + 9
            chondrocyte hypertrophy + 5
            chondrocyte morphogenesis + 1
            negative regulation of chondrocyte development + 3
            positive regulation of chondrocyte development + 1
            regulation of chondrocyte development + 5
Path 2
Term Annotations click to browse term
  biological_process 20045
    developmental process 6824
      anatomical structure development 6290
        multicellular organism development 5766
          system development 5298
            skeletal system development 555
              cartilage development 214
                chondrocyte differentiation 117
                  chondrocyte development 32
                    chondrocyte development involved in endochondral bone morphogenesis + 9
                    chondrocyte hypertrophy + 5
                    chondrocyte morphogenesis + 1
                    negative regulation of chondrocyte development + 3
                    positive regulation of chondrocyte development + 1
                    regulation of chondrocyte development + 5
paths to the root