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ONTOLOGY REPORT - ANNOTATIONS


Term:desensitization of G protein-coupled receptor signaling pathway by arrestin
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Accession:GO:0002032 term browser browse the term
Definition:The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins.
Synonyms:exact_synonym: arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway;   arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway;   desensitization of G-protein coupled receptor protein signaling pathway by arrestin


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desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO
ISS
(PMID:15123695)
GO_REF:0000024
RGD
HGNC-UCL
PMID:15123695 GO_REF:0000024 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 NOT|involved_in ISO (PMID:15123695) RGD PMID:15123695 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP
ISO
(PMID:12582207) RGD PMID:12582207 PMID:20705669 RGD:5509896 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      signal transduction 6882
        negative regulation of signal transduction 1264
          negative adaptation of signaling pathway 31
            desensitization of G protein-coupled receptor signaling pathway 31
              desensitization of G protein-coupled receptor signaling pathway by arrestin 3
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12228
          signal transduction 6882
            regulation of signal transduction 2959
              negative regulation of signal transduction 1264
                negative adaptation of signaling pathway 31
                  desensitization of G protein-coupled receptor signaling pathway 31
                    desensitization of G protein-coupled receptor signaling pathway by arrestin 3
paths to the root