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ONTOLOGY REPORT - ANNOTATIONS


Term:desensitization of G protein-coupled receptor signaling pathway by arrestin
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Accession:GO:0002032 term browser browse the term
Definition:The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins.
Synonyms:exact_synonym: arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway;   arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway;   desensitization of G-protein coupled receptor protein signaling pathway by arrestin


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desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 involved_in IEA
ISS
Ensembl
HGNC-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,032,782...150,035,591
JBrowse link
G ADRB3 adrenoceptor beta 3 NOT|involved_in ISO (PMID:15123695) HGNC-UCL PMID:15123695 NCBI chr15:48,468,803...48,478,370 JBrowse link
G ARRB2 arrestin beta 2 involved_in ISO
IEA
RGD
Ensembl
PMID:20705669 GO_REF:0000107 RGD:5509896 NCBI chr12:52,161,776...52,170,362
Ensembl chr12:52,161,776...52,170,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    cellular process 15862
      signal transduction 6028
        negative regulation of signal transduction 1224
          negative adaptation of signaling pathway 31
            desensitization of G protein-coupled receptor signaling pathway 31
              desensitization of G protein-coupled receptor signaling pathway by arrestin 3
Path 2
Term Annotations click to browse term
  biological_process 16579
    biological regulation 12075
      regulation of biological process 11450
        regulation of cellular process 10982
          signal transduction 6028
            regulation of signal transduction 2845
              negative regulation of signal transduction 1224
                negative adaptation of signaling pathway 31
                  desensitization of G protein-coupled receptor signaling pathway 31
                    desensitization of G protein-coupled receptor signaling pathway by arrestin 3
paths to the root