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ONTOLOGY REPORT - ANNOTATIONS


Term:desensitization of G protein-coupled receptor signaling pathway by arrestin
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Accession:GO:0002032 term browser browse the term
Definition:The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins.
Synonyms:exact_synonym: arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway;   arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway;   desensitization of G-protein coupled receptor protein signaling pathway by arrestin


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desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 involved_in ISO (PMID:15123695) HGNC-UCL PMID:15123695 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G ADRB3 adrenoceptor beta 3 NOT|involved_in ISO (PMID:15123695) HGNC-UCL PMID:15123695 NCBI chr 8:37,263,730...37,267,475 JBrowse link
G ARRB2 arrestin beta 2 involved_in ISO (PMID:12582207) RGD
UniProt
PMID:12582207 PMID:20705669 RGD:5509896 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12657
    cellular process 11790
      signal transduction 3927
        negative regulation of signal transduction 1182
          negative adaptation of signaling pathway 28
            desensitization of G protein-coupled receptor signaling pathway 28
              desensitization of G protein-coupled receptor signaling pathway by arrestin 3
Path 2
Term Annotations click to browse term
  biological_process 12657
    biological regulation 9218
      regulation of biological process 8712
        regulation of cellular process 8230
          signal transduction 3927
            regulation of signal transduction 2618
              negative regulation of signal transduction 1182
                negative adaptation of signaling pathway 28
                  desensitization of G protein-coupled receptor signaling pathway 28
                    desensitization of G protein-coupled receptor signaling pathway by arrestin 3
paths to the root