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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled receptor internalization
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Accession:GO:0002031 term browser browse the term
Definition:The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.


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G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10882736) UniProt PMID:10882736 NCBI chrNW_004936528:8,005,223...8,007,586 JBrowse link
G Arrb1 arrestin beta 1 involved_in ISO (PMID:10521508), (PMID:12582207) UniProt PMID:10521508 PMID:12582207 NCBI chrNW_004936498:4,089,621...4,172,749 JBrowse link
G Arrb2 arrestin beta 2 involved_in ISO (PMID:10644702)
(PMID:12582207)
UniProt PMID:10644702 PMID:12582207 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Calca calcitonin related polypeptide alpha involved_in ISO (PMID:10882736) UniProt PMID:10882736 NCBI chrNW_004936528:3,800,801...3,806,000 JBrowse link
G Dnm1 dynamin 1 ISO RGD PMID:14709338 RGD:9685157 NCBI chrNW_004936487:15,767,897...15,797,722 JBrowse link
G Dnm2 dynamin 2 ISO RGD PMID:14709338 RGD:9685157 NCBI chrNW_004936659:957,408...1,046,393 JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:14617818 RGD:1581465 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Drd3 dopamine receptor D3 involved_in ISO (PMID:18424554) RGD
BHF-UCL
PMID:14617818 PMID:18424554 RGD:1581465 NCBI chrNW_004936536:1,580,732...1,616,726 JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (MGI:4821070|PMID:17325130) UniProt PMID:17325130 MGI:4821070 NCBI chrNW_004936890:154,252...157,044 JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISO (MGI:4821070|PMID:17325130) UniProt PMID:17325130 MGI:4821070 NCBI chrNW_004936525:5,711,894...5,729,074 JBrowse link
G Pld2 phospholipase D2 acts_upstream_of_or_within ISO (MGI:3042801|PMID:14718562) MGI PMID:14718562 MGI:3042801 NCBI chrNW_004936677:2,870,664...2,883,545 JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO (PMID:17689978) UniProt PMID:17689978 NCBI chrNW_004936641:3,779,024...3,802,883 JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) UniProt PMID:18199683 NCBI chrNW_004936819:530,833...534,185 JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) UniProt PMID:25639753 NCBI chrNW_004936555:969,902...978,736 JBrowse link
G Apln apelin involved_in ISO (PMID:11359874)
(MGI:5902690|PMID:11359874)
UniProt PMID:11359874 MGI:5902690 RGD:12907555 NCBI chrNW_004936479:1,889,930...1,899,811 JBrowse link
G LOC101959175 amyloid beta precursor protein involved_in ISO (PMID:18723082) ARUK-UCL PMID:18723082 NCBI chrNW_004936640:1,549,977...1,787,436 JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:15937517 RGD:10043344 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12130
    cellular process 11321
      signal transduction 3817
        negative regulation of signal transduction 1154
          negative adaptation of signaling pathway 27
            desensitization of G protein-coupled receptor signaling pathway 27
              G protein-coupled receptor internalization 17
                negative regulation of G protein-coupled receptor internalization 2
                positive regulation of G protein-coupled receptor internalization 3
                prostaglandin receptor internalization 1
                regulation of G protein-coupled receptor internalization + 5
Path 2
Term Annotations click to browse term
  biological_process 12130
    biological regulation 8863
      regulation of biological process 8396
        regulation of cellular process 7968
          signal transduction 3817
            regulation of signal transduction 2527
              negative regulation of signal transduction 1154
                negative adaptation of signaling pathway 27
                  desensitization of G protein-coupled receptor signaling pathway 27
                    G protein-coupled receptor internalization 17
                      negative regulation of G protein-coupled receptor internalization 2
                      positive regulation of G protein-coupled receptor internalization 3
                      prostaglandin receptor internalization 1
                      regulation of G protein-coupled receptor internalization + 5
paths to the root