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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled receptor internalization
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Accession:GO:0002031 term browser browse the term
Definition:The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.


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G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:49,229,223...49,231,521
Ensembl chr 2:49,229,223...49,231,866
JBrowse link
G ARR3 arrestin 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:56,295,107...56,310,507
Ensembl chr  X:56,296,596...56,310,504
JBrowse link
G ARRB1 arrestin beta 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:9,516,944...9,597,446
Ensembl chr 9:9,513,856...9,597,959
JBrowse link
G ARRB2 arrestin beta 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:52,161,776...52,170,362
Ensembl chr12:52,161,776...52,170,344
JBrowse link
G CALCB calcitonin-related polypeptide beta involved_in ISO (PMID:10882736) UniProt PMID:10882736 NCBI chr 2:44,043,135...44,048,651 JBrowse link
G DNM1 dynamin 1 ISO RGD PMID:14709338 RGD:9685157 NCBI chr 1:268,653,045...268,702,233
Ensembl chr 1:268,653,039...268,702,223
JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:14709338 RGD:9685157 NCBI chr 2:69,474,011...69,574,427
Ensembl chr 2:69,474,031...69,574,424
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:14617818 RGD:1581465 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599
JBrowse link
G DRD3 dopamine receptor D3 involved_in IEA
ISO
Ensembl
RGD
PMID:14617818 GO_REF:0000107 RGD:1581465 NCBI chr13:145,769,294...145,817,997
Ensembl chr13:145,771,510...145,819,173
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO RGD PMID:12519791 RGD:1304268 NCBI chr 8:1,737,960...1,792,390
Ensembl chr 8:1,738,135...1,792,861
JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,597,510...88,598,682
Ensembl chr 1:88,596,215...88,601,047
JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:131,844,578...131,860,417
Ensembl chr15:131,844,928...131,860,392
JBrowse link
G PLD2 phospholipase D2 acts_upstream_of_or_within ISO (MGI:3042801|PMID:14718562) MGI PMID:14718562 MGI:3042801 NCBI chr12:52,073,913...52,087,804
Ensembl chr12:52,073,896...52,087,809
JBrowse link
G SAG S-antigen visual arrestin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:133,704,975...133,741,844
Ensembl chr15:133,691,886...133,741,798
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NECAB2 N-terminal EF-hand calcium binding protein 2 involved_in ISO (PMID:17689978) UniProt PMID:17689978 NCBI chr 6:4,598,752...4,641,450 JBrowse link
G UBQLN2 ubiquilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:48,948,062...48,951,392
Ensembl chr  X:48,948,389...48,950,263
JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APELA apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) UniProt PMID:25639753 NCBI chr 8:53,703,735...53,736,989 JBrowse link
G APLN apelin involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,748...106,246,378
JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:18723082) ARUK-UCL PMID:18723082 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,434,869...189,716,057
JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:15937517 RGD:10043344 NCBI chr 6:141,958,955...142,160,437
Ensembl chr 6:141,958,954...142,161,292
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16534
    cellular process 15812
      signal transduction 6030
        negative regulation of signal transduction 1219
          negative adaptation of signaling pathway 31
            desensitization of G protein-coupled receptor signaling pathway 31
              G protein-coupled receptor internalization 20
                negative regulation of G protein-coupled receptor internalization 2
                positive regulation of G protein-coupled receptor internalization 3
                prostaglandin receptor internalization 1
                regulation of G protein-coupled receptor internalization + 5
Path 2
Term Annotations click to browse term
  biological_process 16534
    biological regulation 12043
      regulation of biological process 11442
        regulation of cellular process 10995
          signal transduction 6030
            regulation of signal transduction 2820
              negative regulation of signal transduction 1219
                negative adaptation of signaling pathway 31
                  desensitization of G protein-coupled receptor signaling pathway 31
                    G protein-coupled receptor internalization 20
                      negative regulation of G protein-coupled receptor internalization 2
                      positive regulation of G protein-coupled receptor internalization 3
                      prostaglandin receptor internalization 1
                      regulation of G protein-coupled receptor internalization + 5
paths to the root