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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled receptor internalization
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Accession:GO:0002031 term browser browse the term
Definition:The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.


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G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10882736) UniProt PMID:10882736 NCBI chrNW_004955414:25,951,473...25,953,593
Ensembl chrNW_004955414:25,951,349...25,953,645
JBrowse link
G Arrb1 arrestin beta 1 involved_in ISO (PMID:10521508), (PMID:12582207) UniProt PMID:10521508 PMID:12582207 NCBI chrNW_004955414:16,478,843...16,568,050
Ensembl chrNW_004955414:16,478,843...16,562,135
JBrowse link
G Arrb2 arrestin beta 2 involved_in ISO (PMID:12582207)
(PMID:10644702)
UniProt PMID:10644702 PMID:12582207 NCBI chrNW_004955467:10,109,985...10,118,687
Ensembl chrNW_004955467:10,110,003...10,123,022
JBrowse link
G Dnm1 dynamin 1 ISO RGD PMID:14709338 RGD:9685157 NCBI chrNW_004955570:752,335...781,770
Ensembl chrNW_004955570:752,335...781,770
JBrowse link
G Dnm2 dynamin 2 ISO RGD PMID:14709338 RGD:9685157 NCBI chrNW_004955495:1,860,644...1,934,589
Ensembl chrNW_004955495:1,860,644...1,934,818
JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:14617818 RGD:1581465 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573
JBrowse link
G Drd3 dopamine receptor D3 involved_in ISO (PMID:18424554) RGD
BHF-UCL
PMID:14617818 PMID:18424554 RGD:1581465 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 ISO RGD PMID:12519791 RGD:1304268 NCBI chrNW_004955514:1,837,141...1,895,785
Ensembl chrNW_004955514:1,837,141...1,895,785
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (MGI:4821070|PMID:17325130) UniProt PMID:17325130 MGI:4821070 NCBI chrNW_004955502:5,640,919...5,646,899
Ensembl chrNW_004955502:5,645,644...5,646,816
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISO (MGI:4821070|PMID:17325130) UniProt PMID:17325130 MGI:4821070 NCBI chrNW_004955453:4,352,278...4,367,807
Ensembl chrNW_004955453:4,351,668...4,367,807
JBrowse link
G Pld2 phospholipase D2 acts_upstream_of_or_within ISO (MGI:3042801|PMID:14718562) MGI PMID:14718562 MGI:3042801 NCBI chrNW_004955467:10,239,177...10,250,516
Ensembl chrNW_004955467:10,239,177...10,250,890
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO (PMID:17689978) UniProt PMID:17689978 NCBI chrNW_004955564:257,781...279,937
Ensembl chrNW_004955564:258,222...277,889
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) UniProt PMID:18199683 NCBI chrNW_004955475:3,260,209...3,263,586
Ensembl chrNW_004955475:3,260,503...3,262,380
JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) UniProt PMID:25639753 NCBI chrNW_004955403:40,257,467...40,266,275 JBrowse link
G Apln apelin involved_in ISO (PMID:11359874)
(MGI:5902690|PMID:11359874)
UniProt PMID:11359874 MGI:5902690 RGD:12907555 NCBI chrNW_004955473:5,346,822...5,356,359
Ensembl chrNW_004955473:5,346,747...5,356,359
JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:18723082) ARUK-UCL PMID:18723082 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:15937517 RGD:10043344 NCBI chrNW_004955423:21,096,926...21,164,435 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11938
    cellular process 11169
      signal transduction 3771
        negative regulation of signal transduction 1147
          negative adaptation of signaling pathway 27
            desensitization of G protein-coupled receptor signaling pathway 27
              G protein-coupled receptor internalization 17
                negative regulation of G protein-coupled receptor internalization 2
                positive regulation of G protein-coupled receptor internalization 3
                prostaglandin receptor internalization 1
                regulation of G protein-coupled receptor internalization + 5
Path 2
Term Annotations click to browse term
  biological_process 11938
    biological regulation 8742
      regulation of biological process 8282
        regulation of cellular process 7863
          signal transduction 3771
            regulation of signal transduction 2510
              negative regulation of signal transduction 1147
                negative adaptation of signaling pathway 27
                  desensitization of G protein-coupled receptor signaling pathway 27
                    G protein-coupled receptor internalization 17
                      negative regulation of G protein-coupled receptor internalization 2
                      positive regulation of G protein-coupled receptor internalization 3
                      prostaglandin receptor internalization 1
                      regulation of G protein-coupled receptor internalization + 5
paths to the root