ONTOLOGY REPORT - ANNOTATIONS
Term: desensitization of G protein-coupled receptor signaling pathway
Accession: GO:0002029
browse the term
Definition: The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway.
Synonyms: exact_synonym: desensitisation of G-protein coupled receptor protein signalling pathway; desensitization of G-protein coupled receptor protein signaling pathway
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Arrb2
arrestin beta 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520
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Gipr
gastric inhibitory polypeptide receptor
ISO
RGD
PMID:8928774
RGD:2312614
NCBI chrNW_004936706:2,052,069...2,062,722
Ensembl chrNW_004936706:2,053,433...2,061,241
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Grk2
G protein-coupled receptor kinase 2
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:7761854) (PMID:10338466)
MGI Ensembl TreeGrafter RGD
PMID:7761854 PMID:10338466 PMID:17908240 PMID:30075183
GO_REF:0000107 GO_REF:0000118 RGD:13792694 RGD:7242040
NCBI chrNW_004936599:2,437,061...2,456,141
Ensembl chrNW_004936599:2,437,032...2,456,147
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Grk3
G protein-coupled receptor kinase 3
involved_in
ISO IEA
RGD TreeGrafter
PMID:8381966 PMID:20837135
GO_REF:0000118 RGD:5685022 RGD:5685621
NCBI chrNW_004936657:425,902...522,331
Ensembl chrNW_004936657:426,787...521,198
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Grk5
G protein-coupled receptor kinase 5
ISO
RGD
PMID:8626574 PMID:30075183
RGD:13792694 RGD:61618
NCBI chrNW_004936486:8,720,036...8,830,472
Ensembl chrNW_004936486:8,720,036...8,831,075
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Grk6
G protein-coupled receptor kinase 6
ISO
RGD
PMID:12810562 PMID:17908240
RGD:1299124 RGD:7242040
NCBI chrNW_004936597:1,706,671...1,722,370
Ensembl chrNW_004936597:1,706,665...1,722,370
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Grm5
glutamate metabotropic receptor 5
involved_in
ISO
PMID:12514208
UniProt
PMID:12514208
RGD:728711
NCBI chrNW_004936736:623,118...1,060,273
Ensembl chrNW_004936736:623,013...1,064,054
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LOC101977693
lymphocyte antigen 6G6e-like
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936727:1,819,792...1,821,533
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Ptger3
prostaglandin E receptor 3
ISO
RGD
PMID:9350980
RGD:9850278
NCBI chrNW_004936591:1,174,364...1,250,233
Ensembl chrNW_004936591:1,174,069...1,249,410
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Adm
adrenomedullin
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936528:8,005,223...8,007,586
Ensembl chrNW_004936528:8,005,189...8,007,643
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Arr3
arrestin 3
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936762:1,194,251...1,207,914
Ensembl chrNW_004936762:1,194,166...1,208,844
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Arrb1
arrestin beta 1
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936498:4,089,621...4,172,749
Ensembl chrNW_004936498:4,094,893...4,172,755
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Arrb2
arrestin beta 2
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520
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Calca
calcitonin related polypeptide alpha
involved_in
ISO
(PMID:10882736)
UniProt
PMID:10882736
NCBI chrNW_004936528:3,800,801...3,806,000
Ensembl chrNW_004936528:3,800,577...3,805,004
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Dnm1
dynamin 1
ISO
RGD
PMID:14709338
RGD:9685157
NCBI chrNW_004936487:15,767,897...15,797,722
Ensembl chrNW_004936487:15,767,897...15,801,211
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Dnm2
dynamin 2
ISO
RGD
PMID:14709338
RGD:9685157
NCBI chrNW_004936659:957,408...1,046,393
Ensembl chrNW_004936659:957,392...1,049,188
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Drd2
dopamine receptor D2
ISO
RGD
PMID:14617818
RGD:1581465
NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798
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Drd3
dopamine receptor D3
involved_in
ISO IEA
RGD Ensembl
PMID:14617818
GO_REF:0000107 RGD:1581465
NCBI chrNW_004936536:1,580,732...1,616,726
Ensembl chrNW_004936536:1,580,732...1,616,725
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LOC101957203
general transcription factor IIH subunit 2
involved_in
ISO
(PMID:15775968)
UniProt
PMID:15775968
NCBI chrNW_004936480:72,730...92,868
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Pld2
phospholipase D2
acts_upstream_of_or_within
ISO
(PMID:14718562)
MGI
PMID:14718562
NCBI chrNW_004936677:2,870,664...2,883,545
Ensembl chrNW_004936677:2,870,660...2,883,567
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Sag
S-antigen visual arrestin
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936525:3,932,118...3,965,651
Ensembl chrNW_004936525:3,931,933...3,964,834
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Camk2b
calcium/calmodulin dependent protein kinase II beta
acts_upstream_of_or_within
ISO
(PMID:19332541)
MGI
PMID:19332541
NCBI chrNW_004936478:19,183,493...19,278,457
Ensembl chrNW_004936478:19,180,726...19,278,920
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Necab2
N-terminal EF-hand calcium binding protein 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936641:3,779,024...3,802,883
Ensembl chrNW_004936641:3,779,374...3,799,581
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Ubqln2
ubiquilin 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936819:530,833...534,185
Ensembl chrNW_004936819:532,037...533,920
G
Apela
apelin receptor early endogenous ligand
involved_in
ISO
(PMID:25639753)
UniProt
PMID:25639753
NCBI chrNW_004936555:969,902...978,736
G
Apln
apelin
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936479:1,889,930...1,899,811
Ensembl chrNW_004936479:1,890,229...1,899,730
G
Aplnr
apelin receptor
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936581:5,230,836...5,234,562
Ensembl chrNW_004936581:5,231,242...5,232,384
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App
amyloid beta precursor protein
involved_in
ISO
(PMID:18723082)
ARUK-UCL
PMID:18723082
NCBI chrNW_004936640:1,549,977...1,787,436
Ensembl chrNW_004936640:1,550,167...1,787,286
G
Ptger3
prostaglandin E receptor 3
ISO
RGD
PMID:15937517
RGD:10043344
NCBI chrNW_004936591:1,174,364...1,250,233
Ensembl chrNW_004936591:1,174,069...1,249,410
G
Ptger3
prostaglandin E receptor 3
ISO
RGD
PMID:15937517
RGD:10043344
NCBI chrNW_004936591:1,174,364...1,250,233
Ensembl chrNW_004936591:1,174,069...1,249,410
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