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ONTOLOGY REPORT - ANNOTATIONS

Term:response to amphetamine
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Accession:GO:0001975 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.


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response to amphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO MGI:2155985 (MGI:1930839|PMID:11172060) RGD PMID:11172060 MGI:1930839 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO MGI:2148638 (MGI:2178201|PMID:11923452), (MGI:2667580|PMID:12871582) RGD PMID:11923452 PMID:12871582 MGI:2178201 MGI:2667580 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Asic1 acid sensing ion channel subunit 1 acts_upstream_of_or_within ISO (MGI:6108223|PMID:25828470) RGD PMID:25828470 MGI:6108223 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Calm1 calmodulin 1 IEP RGD PMID:10854758 RGD:6892957 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 IEP RGD PMID:10854758 RGD:6892957 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287 		JBrowse link
G Calm3 calmodulin 3 IEP RGD PMID:10854758 RGD:6892957 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Cnr2 cannabinoid receptor 2 IEP RGD PMID:20067581 RGD:2316187 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP RGD PMID:19582783 RGD:2314489 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP RGD PMID:19582783 RGD:2314489 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857556 (MGI:3574756|PMID:12370425)		 Ensembl
RGD		 PMID:12370425 GO_REF:0000107 MGI:3574756 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Dcc DCC netrin 1 receptor IEP RGD PMID:17996376 RGD:2314370 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEP RGD PMID:17105900 RGD:1599727 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 IEP RGD PMID:20058175 RGD:2316239 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IEP
IEA
ISO		 GO_REF:0000107
MGI:1857158|MGI:2159306|MGI:3527157|MGI:94924|MGI:94925|MGI:94927|MGI:95819 (MGI:1195902|PMID:9261820), (MGI:1351083|PMID:10661513), (MGI:2137377|PMID:10222120), (MGI:3610905|PMID:11823893), (MGI:3626135|PMID:12097513), (MGI:3711455|PMID:16014726), (MGI:3797707|PMID:18486343), (MGI:4947459|PMID:21368124)		 Ensembl
RGD		 PMID:9261820 PMID:10222120 PMID:10661513 PMID:11823893 PMID:12097513 More... GO_REF:0000107 MGI:1195902 MGI:1351083 MGI:2137377 MGI:3610905 MGI:3626135 MGI:3711455 MGI:3797707 MGI:4947459, RGD:2311558 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within IEP
ISO		 MGI:1857875|MGI:94925|MGI:99578 (MGI:3626135|PMID:12097513), (MGI:3797707|PMID:18486343)
MGI:2656648 (MGI:3611062|PMID:12476322)		 RGD PMID:12097513 PMID:12476322 PMID:18486343 PMID:19145071 MGI:3611062 MGI:3626135 MGI:3797707, RGD:2311558 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO MGI:94924|MGI:99578 (MGI:3626135|PMID:12097513) RGD PMID:12097513 MGI:3626135 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178631 (MGI:1097029|PMID:9323127)		 Ensembl
RGD		 PMID:9323127 GO_REF:0000107 MGI:1097029 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Drd5 dopamine receptor D5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:99578 (MGI:3610905|PMID:11823893)		 Ensembl
RGD		 PMID:11823893 GO_REF:0000107 MGI:3610905 NCBI chr14:72,489,347...72,490,774
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (MGI:6100594|PMID:24875861) RGD PMID:24875861 MGI:6100594 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:1857473 (MGI:6100594|PMID:24875861) RGD PMID:24875861 MGI:6100594 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Egr1 early growth response 1 IEP methamphetamine RGD PMID:21229349 RGD:5131852 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Gnal G protein subunit alpha L acts_upstream_of_or_within ISO MGI:2151207 (MGI:3719553|PMID:11404425) RGD PMID:11404425 MGI:3719553 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 acts_upstream_of_or_within ISO MGI:1928280|MGI:99578 (MGI:3629445|PMID:16638606), (MGI:3784348|PMID:15467708), (MGI:4947459|PMID:21368124) RGD PMID:15467708 PMID:16638606 PMID:21368124 MGI:3629445 MGI:3784348 MGI:4947459 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1928285 (MGI:3656418|PMID:15731593)		 Ensembl
RGD		 PMID:15731593 GO_REF:0000107 MGI:3656418 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP RGD PMID:20422365 RGD:4107018 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Hdac1 histone deacetylase 1 IMP RGD PMID:18632938 RGD:9586741 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 IEP RGD PMID:22470541 RGD:9590269 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac6 histone deacetylase 6 IEP RGD PMID:25452209 RGD:9681719 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Hdac9 histone deacetylase 9 IEP RGD PMID:25452209 RGD:9681719 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 acts_upstream_of_or_within ISO MGI:1857299 (MGI:50371|PMID:1777100), (MGI:65928|PMID:1432691) RGD PMID:1432691 PMID:1777100 MGI:50371 MGI:65928 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:21093552 RGD:4889145 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 IMP RGD PMID:29530712 RGD:40924655 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2429971 (MGI:3529728|PMID:12385813)		 Ensembl
RGD		 PMID:12385813 GO_REF:0000107 MGI:3529728 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nts neurotensin IEP RGD PMID:9786410 RGD:9698453 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IEP RGD PMID:17383105 RGD:2304140 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:17383105 RGD:2304140 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Pde1b phosphodiesterase 1B acts_upstream_of_or_within ISO MGI:2676625|MGI:3604470|MGI:94860 (MGI:3761427|PMID:17010100), (MGI:3769297|PMID:17559891) RGD PMID:17010100 PMID:17559891 MGI:3761427 MGI:3769297 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B acts_upstream_of_or_within ISO MGI:3799291|MGI:97523 (MGI:3761427|PMID:17010100), (MGI:3797712|PMID:18496528) RGD PMID:17010100 PMID:18496528 MGI:3761427 MGI:3797712 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IEP RGD PMID:19932152 RGD:9999394 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IEP reduced protein in brain striatum particulate fraction, unchanged in soluble fraction, of methamphetamine-treated rats RGD PMID:11954050 RGD:727362 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IEP reduced protein in brain striatum particulate fraction, unchanged in soluble fraction, of methamphetamine-treated rats RGD PMID:11954050 RGD:727362 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IEP RGD PMID:23711322 RGD:9835030 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882 		JBrowse link
G Ranbp2 RAN binding protein 2 IEP methamphetamine RGD PMID:23711322 RGD:9835030 NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEP RGD PMID:19686726 RGD:10003122 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 IEP RGD PMID:26321241 RGD:13524514 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs17 regulator of G-protein signaling 17 IEP RGD PMID:26321241 RGD:13524514 NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 IEP RGD PMID:26321241 RGD:13524514 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs20 regulator of G-protein signaling 20 IEP RGD PMID:26321241 RGD:13524514 NCBI chr 5:14,484,320...14,614,321
Ensembl chr 5:14,534,775...14,614,084 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IEP RGD PMID:26321241 RGD:13524514 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 IEP RGD PMID:26321241 RGD:13524514 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 IEP RGD PMID:26321241 RGD:13524514 NCBI chr13:65,804,703...65,848,953
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 IEP RGD PMID:26321241 RGD:13524514 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in
acts_upstream_of_or_within		 IEP
IEA
ISO		 methamphetamine
GO_REF:0000107
MGI:3620458 (MGI:1096299|PMID:9275230)		 Ensembl
RGD		 PMID:9275230 PMID:21159748 GO_REF:0000107 MGI:1096299, RGD:5130776 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:5904876|PMID:28507136) RGD PMID:28507136 MGI:5904876 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Sod1 superoxide dismutase 1 IEP RGD PMID:18452277 RGD:2302826 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase IEP RGD PMID:18632938 RGD:9586741 NCBI chr  X:14,421,028...14,434,216
Ensembl chr  X:14,421,109...14,433,982 		JBrowse link
G Th tyrosine hydroxylase IEP RGD PMID:21078367 RGD:5128808 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 IEP RGD PMID:15542706 RGD:2303196 NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    response to stimulus 10569
      response to chemical 6107
        response to nitrogen compound 1644
          response to organonitrogen compound 1569
            response to amine 89
              response to amphetamine 58
                cellular response to amphetamine 0
paths to the root