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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:G protein-coupled adenosine receptor signaling pathway
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Accession:GO:0001973 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
Synonyms:exact_synonym: P1 receptor signaling pathway;   adenosine receptor signalling pathway
 related_synonym: adenosine receptor signaling pathway

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G protein-coupled adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12223546) Ensembl
MGI		 PMID:12223546 GO_REF:0000107 NCBI chrNW_004936725:1,751,272...1,897,937
Ensembl chrNW_004936725:1,751,266...1,897,946 		JBrowse link
G Adora1 adenosine A1 receptor involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936567:1,430,128...1,508,626
Ensembl chrNW_004936567:1,429,817...1,462,532 		JBrowse link
G Adora2a adenosine A2a receptor involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:80600|PMID:8738226), (PMID:12223546)
(PMID:10845921)
(PMID:12223546)		 RGD
TreeGrafter
MGI
Ensembl
InterPro		 PMID:8738226 PMID:10845921 PMID:12223546 PMID:12590138 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 MGI:80600 RGD:1625697 NCBI chrNW_004936619:597,970...618,564
Ensembl chrNW_004936619:608,441...616,779 		JBrowse link
G Adora2b adenosine A2b receptor involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936821:583,463...608,189
Ensembl chrNW_004936821:580,675...608,245 		JBrowse link
G ADORA3 adenosine A3 receptor involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chrNW_004936690:164,794...168,614 JBrowse link
G Gnai2 G protein subunit alpha i2 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:11923410 GO_REF:0000118 RGD:625670 NCBI chrNW_004936529:1,779,582...1,801,251
Ensembl chrNW_004936529:1,779,571...1,801,255 		JBrowse link
G LOC101973578 adenosine receptor A3 acts_upstream_of_or_within ISO (PMID:12817016) MGI PMID:12817016 NCBI chrNW_004936690:152,777...168,411 JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in ISO PMID:20847060 BHF-UCL PMID:20847060 RGD:8554370 NCBI chrNW_004936519:865,756...872,466
Ensembl chrNW_004936519:866,208...872,393 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in ISO
IEA		 RGD
GOC		 PMID:12814667 GO_REF:0000108 RGD:6482299 NCBI chrNW_004936758:1,581,828...1,624,332
Ensembl chrNW_004936758:1,581,897...1,592,222 		JBrowse link
negative regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G LOC101972479 adenosine deaminase-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936530:2,034,514...2,041,099 JBrowse link
positive regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 involved_in IEA
ISS		 Ensembl
CAFA		 GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004936529:5,661,772...5,723,108
Ensembl chrNW_004936529:5,661,702...5,725,363 		JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936641:3,779,024...3,802,883
Ensembl chrNW_004936641:3,779,374...3,799,581 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    cellular process 15075
      signal transduction 5702
        G protein-coupled receptor signaling pathway 1495
          G protein-coupled purinergic receptor signaling pathway 13
            G protein-coupled adenosine receptor signaling pathway 13
              negative regulation of adenosine receptor signaling pathway 2
              positive regulation of adenosine receptor signaling pathway 2
              regulation of adenosine receptor signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 15969
    biological regulation 11154
      regulation of biological process 10818
        regulation of cellular process 10346
          signal transduction 5702
            cell surface receptor signaling pathway 2527
              purinergic nucleotide receptor signaling pathway 33
                G protein-coupled purinergic receptor signaling pathway 13
                  G protein-coupled adenosine receptor signaling pathway 13
                    negative regulation of adenosine receptor signaling pathway 2
                    positive regulation of adenosine receptor signaling pathway 2
                    regulation of adenosine receptor signaling pathway + 4
paths to the root