Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of activation of membrane attack complex
go back to main search page
Accession:GO:0001971 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: down regulation of activation of membrane attack complex;   downregulation of activation of membrane attack complex;   negative regulation of MAC assembly;   negative regulation of MAC formation;   negative regulation of activation of MAC;   negative regulation of membrane attack complex assembly;   negative regulation of membrane attack complex formation
 narrow_synonym: inhibition of activation of membrane attack complex;   negative regulation of activation of TCC;   negative regulation of activation of terminal complement complex;   negative regulation of activation of the terminal complement cascade

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (PMID:10946279), (PMID:11471050) RGD
MGI		 PMID:10946279 PMID:11471050 PMID:15843577 RGD:1600482 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G LOC101964865 complement receptor type 1 acts_upstream_of ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    immune system process 2209
      immune effector process 586
        complement activation 46
          negative regulation of complement activation 13
            negative regulation of activation of membrane attack complex 2
Path 2
Term Annotations click to browse term
  biological_process 15969
    biological regulation 11154
      regulation of biological process 10818
        regulation of immune system process 1427
          positive regulation of immune system process 1006
            positive regulation of immune response 666
              activation of immune response 488
                complement activation 46
                  activation of membrane attack complex 4
                    regulation of activation of membrane attack complex 4
                      negative regulation of activation of membrane attack complex 2
paths to the root