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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of activation of membrane attack complex
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Accession:GO:0001971 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: down regulation of activation of membrane attack complex;   downregulation of activation of membrane attack complex;   negative regulation of MAC assembly;   negative regulation of MAC formation;   negative regulation of activation of MAC;   negative regulation of membrane attack complex assembly;   negative regulation of membrane attack complex formation
 narrow_synonym: inhibition of activation of membrane attack complex;   negative regulation of activation of TCC;   negative regulation of activation of terminal complement complex;   negative regulation of activation of the terminal complement cascade



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negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59a CD59a antigen involved_in
acts_upstream_of_or_within
IBA
ISO
IDA
IMP
(MGI:6201960|PMID:21873635)
(MGI:2148385|PMID:11471050)
(MGI:3828358|PMID:17237428)
GO_Central
MGI
BHF-UCL
PMID:11471050 PMID:17237428 PMID:21873635 GO_REF:0000096 MGI:2148385 MGI:3828358 MGI:4417868 MGI:6201960 NCBI chr 2:103,926,101...103,945,755
Ensembl chr 2:103,926,146...103,945,699
JBrowse link
G Cd59b CD59b antigen acts_upstream_of_or_within
involved_in
IDA
IBA
ISO
(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
RGD
PMID:10946279 PMID:11471050 PMID:15843577 PMID:21873635 GO_REF:0000096 MGI:1888643 MGI:2148385 MGI:4417868 MGI:6201960 RGD:1600482 NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,900,194...103,921,532
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28749
    immune system process 3143
      immune effector process 857
        complement activation 188
          negative regulation of complement activation 15
            negative regulation of activation of membrane attack complex 2
Path 2
Term Annotations click to browse term
  biological_process 28749
    biological regulation 13623
      regulation of biological process 12965
        regulation of immune system process 1726
          positive regulation of immune system process 1134
            positive regulation of immune response 721
              activation of immune response 459
                complement activation 188
                  activation of membrane attack complex 5
                    regulation of activation of membrane attack complex 4
                      negative regulation of activation of membrane attack complex 2
paths to the root