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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of activation of membrane attack complex
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Accession:GO:0001971 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: down regulation of activation of membrane attack complex;   downregulation of activation of membrane attack complex;   negative regulation of MAC assembly;   negative regulation of MAC formation;   negative regulation of activation of MAC;   negative regulation of membrane attack complex assembly;   negative regulation of membrane attack complex formation
 narrow_synonym: inhibition of activation of membrane attack complex;   negative regulation of activation of TCC;   negative regulation of activation of terminal complement complex;   negative regulation of activation of the terminal complement cascade



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negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59 CD59 molecule involved_in
acts_upstream_of_or_within
IDA
IBA
ISO
PMID:21873635
(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050)
RGD PMID:10946279 PMID:11471050 PMID:15843577 PMID:21873635 MGI:1888643 MGI:2148385, RGD:1600482, RGD:13792537 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    immune system process 2885
      immune effector process 729
        complement activation 166
          negative regulation of complement activation 14
            negative regulation of activation of membrane attack complex 1
Path 2
Term Annotations click to browse term
  biological_process 19834
    biological regulation 13775
      regulation of biological process 13033
        regulation of immune system process 1543
          positive regulation of immune system process 1020
            positive regulation of immune response 640
              activation of immune response 413
                complement activation 166
                  activation of membrane attack complex 4
                    regulation of activation of membrane attack complex 3
                      negative regulation of activation of membrane attack complex 1
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