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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of activation of membrane attack complex
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Accession:GO:0001970 term browser browse the term
Definition:Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: positive regulation of MAC assembly;   positive regulation of MAC formation;   positive regulation of activation of MAC;   positive regulation of membrane attack complex assembly;   positive regulation of membrane attack complex formation;   up regulation of activation of membrane attack complex;   upregulation of activation of membrane attack complex
 narrow_synonym: activation of activation of membrane attack complex;   positive regulation of activation of TCC;   positive regulation of activation of terminal complement complex;   positive regulation of activation of the terminal complement cascade;   stimulation of activation of membrane attack complex


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positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chrNW_004936518:1,471,116...1,532,733 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14975
    immune system process 2162
      immune effector process 539
        complement activation 44
          positive regulation of complement activation 6
            positive regulation of activation of membrane attack complex 3
Path 2
Term Annotations click to browse term
  biological_process 14975
    biological regulation 10700
      regulation of biological process 10151
        regulation of immune system process 1285
          positive regulation of immune system process 793
            positive regulation of immune response 442
              activation of immune response 238
                complement activation 44
                  activation of membrane attack complex 4
                    regulation of activation of membrane attack complex 4
                      positive regulation of activation of membrane attack complex 3
paths to the root