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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of activation of membrane attack complex
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Accession:GO:0001970 term browser browse the term
Definition:Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: positive regulation of MAC assembly;   positive regulation of MAC formation;   positive regulation of activation of MAC;   positive regulation of membrane attack complex assembly;   positive regulation of membrane attack complex formation;   up regulation of activation of membrane attack complex;   upregulation of activation of membrane attack complex
 narrow_synonym: activation of activation of membrane attack complex;   positive regulation of activation of TCC;   positive regulation of activation of terminal complement complex;   positive regulation of activation of the terminal complement cascade;   stimulation of activation of membrane attack complex



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positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:41,142,116...41,261,469
Ensembl chr 5:41,142,116...41,261,438
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IMP (PMID:11981823) ARUK-UCL
ARUK-UCL
PMID:11981823 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19656
    immune system process 3246
      immune effector process 784
        complement activation 153
          positive regulation of complement activation 9
            positive regulation of activation of membrane attack complex 3
Path 2
Term Annotations click to browse term
  biological_process 19656
    biological regulation 13816
      regulation of biological process 13079
        regulation of immune system process 1729
          positive regulation of immune system process 1108
            positive regulation of immune response 687
              activation of immune response 452
                complement activation 153
                  activation of membrane attack complex 6
                    regulation of activation of membrane attack complex 5
                      positive regulation of activation of membrane attack complex 3
paths to the root