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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of activation of membrane attack complex
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Accession:GO:0001970 term browser browse the term
Definition:Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: positive regulation of MAC assembly;   positive regulation of MAC formation;   positive regulation of activation of MAC;   positive regulation of membrane attack complex assembly;   positive regulation of membrane attack complex formation;   up regulation of activation of membrane attack complex;   upregulation of activation of membrane attack complex
 narrow_synonym: activation of activation of membrane attack complex;   positive regulation of activation of TCC;   positive regulation of activation of terminal complement complex;   positive regulation of activation of the terminal complement cascade;   stimulation of activation of membrane attack complex



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positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:69,174,411...69,245,801
Ensembl chr 5:74,216,244...74,288,588
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chr 1:183,094,601...183,246,957 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15332
    immune system process 2278
      immune effector process 586
        complement activation 48
          positive regulation of complement activation 7
            positive regulation of activation of membrane attack complex 3
Path 2
Term Annotations click to browse term
  biological_process 15332
    biological regulation 10946
      regulation of biological process 10347
        regulation of immune system process 1341
          positive regulation of immune system process 840
            positive regulation of immune response 475
              activation of immune response 259
                complement activation 48
                  activation of membrane attack complex 5
                    regulation of activation of membrane attack complex 4
                      positive regulation of activation of membrane attack complex 3
paths to the root