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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of activation of membrane attack complex
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Accession:GO:0001969 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: regulation of MAC assembly;   regulation of MAC formation;   regulation of activation of MAC;   regulation of membrane attack complex assembly;   regulation of membrane attack complex formation
 narrow_synonym: regulation of activation of TCC;   regulation of activation of terminal complement complex;   regulation of activation of the terminal complement cascade


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negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59b CD59b molecule involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA
ISO		 GO_REF:0000118
GO_REF:0000033
(PMID:10946279), (PMID:11471050)		 TreeGrafter
GO_Central
RGD		 PMID:10946279 PMID:11471050 PMID:15843577 GO_REF:0000033 GO_REF:0000118, RGD:1600482 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G LOC134480016 urinary protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Rup2 urinary protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:35,336,764...35,340,345
Ensembl chr 8:35,336,764...35,489,103 		JBrowse link
G Rup2l2 urinary protein 2 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:35,750,482...35,754,083
Ensembl chr 8:35,750,482...35,754,071 		JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4430818|PMID:15611275)		 Ensembl
RGD		 PMID:15611275 GO_REF:0000107 MGI:4430818 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) RGD PMID:15611275 MGI:4430818 NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      immune effector process 838
        complement activation 73
          activation of membrane attack complex 7
            regulation of activation of membrane attack complex 6
              negative regulation of activation of membrane attack complex 4
              positive regulation of activation of membrane attack complex 2
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        positive regulation of biological process 6814
          positive regulation of response to stimulus 2552
            positive regulation of immune response 804
              activation of immune response 572
                complement activation 73
                  activation of membrane attack complex 7
                    regulation of activation of membrane attack complex 6
                      negative regulation of activation of membrane attack complex 4
                      positive regulation of activation of membrane attack complex 2
paths to the root