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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of activation of membrane attack complex
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Accession:GO:0001969 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: regulation of MAC assembly;   regulation of MAC formation;   regulation of activation of MAC;   regulation of membrane attack complex assembly;   regulation of membrane attack complex formation
 narrow_synonym: regulation of activation of TCC;   regulation of activation of terminal complement complex;   regulation of activation of the terminal complement cascade


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negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD59 CD59 molecule (CD59 blood group) involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:10946279), (PMID:11471050) RGD
TreeGrafter
MGI		 PMID:10946279 PMID:11471050 PMID:15843577 GO_REF:0000118 RGD:1600482 NCBI chr11:33,680,580...33,708,479
Ensembl chr11:33,552,164...33,590,157 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) acts_upstream_of ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 1:183,094,601...183,246,957 JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699 		JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:69,174,411...69,245,801
Ensembl chr 5:74,216,244...74,288,588 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chr 1:183,094,601...183,246,957 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    immune system process 2386
      immune effector process 638
        complement activation 54
          activation of membrane attack complex 5
            regulation of activation of membrane attack complex 4
              negative regulation of activation of membrane attack complex 2
              positive regulation of activation of membrane attack complex 3
Path 2
Term Annotations click to browse term
  biological_process 16313
    biological regulation 11327
      regulation of biological process 10982
        positive regulation of biological process 6279
          positive regulation of response to stimulus 2337
            positive regulation of immune response 704
              activation of immune response 519
                complement activation 54
                  activation of membrane attack complex 5
                    regulation of activation of membrane attack complex 4
                      negative regulation of activation of membrane attack complex 2
                      positive regulation of activation of membrane attack complex 3
paths to the root