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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of activation of membrane attack complex
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Accession:GO:0001969 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:exact_synonym: regulation of MAC assembly;   regulation of MAC formation;   regulation of activation of MAC;   regulation of membrane attack complex assembly;   regulation of membrane attack complex formation
 narrow_synonym: regulation of activation of TCC;   regulation of activation of terminal complement complex;   regulation of activation of the terminal complement cascade



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negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59 CD59 molecule involved_in
acts_upstream_of_or_within
IDA
IBA
ISO
PMID:21873635
(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050)
RGD PMID:10946279 PMID:11471050 PMID:15843577 PMID:21873635 MGI:1888643 MGI:2148385, RGD:1600482, RGD:13792537 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISO
GO_REF:0000107
(MGI:4430818|PMID:15611275)
Ensembl
RGD
PMID:15611275 GO_REF:0000107 MGI:4430818 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) RGD PMID:15611275 MGI:4430818 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    immune system process 2730
      immune effector process 678
        complement activation 94
          activation of membrane attack complex 4
            regulation of activation of membrane attack complex 3
              negative regulation of activation of membrane attack complex 1
              positive regulation of activation of membrane attack complex 2
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        positive regulation of biological process 6662
          positive regulation of response to stimulus 2330
            positive regulation of immune response 568
              activation of immune response 340
                complement activation 94
                  activation of membrane attack complex 4
                    regulation of activation of membrane attack complex 3
                      negative regulation of activation of membrane attack complex 1
                      positive regulation of activation of membrane attack complex 2
paths to the root