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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of leukocyte mediated cytotoxicity
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Accession:GO:0001910 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity.
Synonyms:exact_synonym: regulation of immune cell mediated cell death;   regulation of immune cell mediated cell killing;   regulation of immune cell mediated cytotoxicity;   regulation of leucocyte mediated cytotoxicity



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negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
negative regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3639805|PMID:16732273)
UniProt
RGD
PMID:16732273 GO_REF:0000024 MGI:3639805 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:18604210) RGD PMID:18604210 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Clec12b C-type lectin domain family 12, member B involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:162,827,462...162,843,821
Ensembl chr 4:162,827,462...162,838,946
JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:18835194 RGD:11568650 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:9021955 RGD:9685777 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
JBrowse link
G Igf2 insulin-like growth factor 2 IDA RGD PMID:9021955 RGD:9685777 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206), (PMID:9486650) RGD PMID:9485206 PMID:9486650 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
ISS
(PMID:9486650)
GO_REF:0000024
RGD
UniProt
PMID:9486650 GO_REF:0000024 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:78,372,138...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IMP RGD PMID:10837412 RGD:2313500 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:10190900), (PMID:12874224) RGD PMID:10190900 PMID:12874224 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:3641175 (MGI:3639618|PMID:16127454) RGD PMID:16127454 MGI:3639618 NCBI chr13:82,416,362...82,461,511
Ensembl chr13:82,437,428...82,461,509
JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:23696226)
(MGI:5512785|PMID:23696226)
GO_REF:0000024
RGD
UniProt
PMID:23696226 GO_REF:0000024 MGI:5512785 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,032,938...163,041,641
Ensembl chr 4:163,033,563...163,041,638
JBrowse link
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (MGI:893318|PMID:9215624) RGD PMID:9215624 MGI:893318 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206) RGD PMID:9485206 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
ISS
(PMID:9485206)
GO_REF:0000024
RGD
UniProt
PMID:9485206 GO_REF:0000024 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta acts_upstream_of_or_within ISO MGI:2181294 (MGI:3772519|PMID:18097009) RGD PMID:18097009 MGI:3772519 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO
GO_REF:0000024
(MGI:3654612|PMID:9725213)
UniProt
RGD
PMID:9725213 GO_REF:0000024 MGI:3654612 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,229 JBrowse link
positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
positive regulation of leukocyte mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:8103296 RGD:8549560 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgam integrin subunit alpha M involved_in ISO (MGI:3812233|PMID:18685038) RGD PMID:18685038 MGI:3812233 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6093262|PMID:28628103) RGD PMID:28628103 MGI:6093262 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in IBA
ISO
PMID:21873635
(MGI:3812233|PMID:18685038)
RGD PMID:18685038 PMID:21873635 MGI:3812233, RGD:13792537 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,666...37,831,131
Ensembl chr19:37,744,633...37,829,167
JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA
(PMID:23632890)
GO_REF:0000107
RGD
Ensembl
PMID:23632890 GO_REF:0000107 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,666...37,831,131
Ensembl chr19:37,744,633...37,829,167
JBrowse link
G Cadm1 cell adhesion molecule 1 involved_in ISO
ISS
(PMID:15811952)
(MGI:3689781|PMID:15811952)
GO_REF:0000024
RGD
HGNC
PMID:15811952 GO_REF:0000024 MGI:3689781 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:12486241), (PMID:17307798) RGD PMID:12486241 PMID:17307798 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
JBrowse link
G Cd226 CD226 molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:15811952)
(MGI:3689781|PMID:15811952)
RGD PMID:15811952 MGI:3689781 NCBI chr 8:41,340,117...41,377,343
Ensembl chr 8:41,340,837...41,377,343
JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:2204066) RGD PMID:2204066 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il18rap interleukin 18 receptor accessory protein acts_upstream_of_or_within ISO MGI:3579137 (MGI:3578455|PMID:15843532) RGD PMID:15843532 MGI:3578455 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959
JBrowse link
G Il21 interleukin 21 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:18005035)
(MGI:3028812|PMID:14764669)
PMID:21873635
RGD PMID:14764669 PMID:18005035 PMID:21873635 MGI:3028812, RGD:13792537 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Klrb1c killer cell lectin like receptor B1C acts_upstream_of_or_within ISO (MGI:1336837|PMID:10229828), (MGI:1336838|PMID:10229823) RGD PMID:10229823 PMID:10229828 MGI:1336837 MGI:1336838 NCBI chr 4:162,380,773...162,394,688
Ensembl chr 4:162,381,602...162,393,786
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:9754572) RGD PMID:9754572 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843
JBrowse link
G Klrc3 killer cell lectin like receptor C3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:163,106,024...163,112,336
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IBA
(PMID:9754572)
PMID:21873635
RGD PMID:9754572 PMID:21873635 RGD:13792537 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 involved_in ISO
IBA
(PMID:15294961)
PMID:21873635
RGD PMID:15294961 PMID:21873635 RGD:13792537 NCBI chr 4:163,032,938...163,041,641
Ensembl chr 4:163,033,563...163,041,638
JBrowse link
G Klrh1 killer cell lectin-like receptor subfamily H, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,288,228...163,301,977
Ensembl chr 4:163,288,229...163,300,535
JBrowse link
G Klri1 killer cell lectin-like receptor family I member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,183,675...163,218,903
Ensembl chr 4:163,183,669...163,218,870
JBrowse link
G Klri2 killer cell lectin-like receptor family I member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,252,844...163,261,484
Ensembl chr 4:163,252,844...163,261,484
JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
IBA
GO_REF:0000024
(MGI:3054301|PMID:15294961)
(MGI:2450811|PMID:12645935)
GO_REF:0000107
(PMID:15294961)
PMID:21873635
UniProt
RGD
Ensembl
PMID:12645935 PMID:15294961 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:2450811 MGI:3054301, RGD:13792537 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Lag3 lymphocyte activating 3 acts_upstream_of_or_within ISO MGI:2176269 (MGI:80003|PMID:8602528) RGD PMID:8602528 MGI:80003 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like acts_upstream_of_or_within ISO MGI:3701255 (MGI:3700871|PMID:16476767) RGD PMID:16476767 MGI:3700871
G Ly49s3 Ly-49 stimulatory receptor 3 IDA RGD PMID:12077224 RGD:633264 Ensembl chr 4:164,122,072...164,341,692 JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO
IEA
IBA
(PMID:16304049)
GO_REF:0000002
PMID:21873635
RGD
InterPro
PMID:16304049 PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Raet1e retinoic acid early transcript 1E involved_in ISO (PMID:18544572) RGD PMID:18544572 NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755
JBrowse link
G Raet1l retinoic acid early transcript 1L IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) RGD PMID:19933860 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Rrlt similar to retinoic acid early transcript 1L IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:23335510) RGD PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:23335510) RGD PMID:23335510 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Sh2d1a SH2 domain containing 1A acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1349420|MGI:3575311|MGI:3622649 (MGI:3639618|PMID:16127454), (MGI:4355255|PMID:19648922)
PMID:21873635
RGD PMID:16127454 PMID:19648922 PMID:21873635 MGI:3639618 MGI:4355255, RGD:13792537 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:1328352|MGI:1349420|MGI:98923 (MGI:4355255|PMID:19648922), (MGI:4839659|PMID:20962259) RGD PMID:19648922 PMID:20962259 MGI:4355255 MGI:4839659 NCBI chr13:82,416,362...82,461,511
Ensembl chr13:82,437,428...82,461,509
JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:16920955) RGD PMID:16920955 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:1857249 (MGI:3655409|PMID:9841920) RGD PMID:9841920 MGI:3655409 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181592 (MGI:3655409|PMID:9841920)
Ensembl
RGD
PMID:9841920 GO_REF:0000107 MGI:3655409 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1349420|MGI:3622649 (MGI:4839659|PMID:20962259)
GO_REF:0000107
RGD
Ensembl
PMID:20962259 GO_REF:0000107 MGI:4839659 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in IBA
ISO
PMID:21873635
(PMID:12913096)
RGD PMID:12913096 PMID:21873635 RGD:13792537 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in IBA
ISO
PMID:21873635
(MGI:3689781|PMID:15811952)
(PMID:15811952)
RGD PMID:15811952 PMID:21873635 MGI:3689781, RGD:13792537 NCBI chr 8:41,340,117...41,377,343
Ensembl chr 8:41,340,837...41,377,343
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IBA
ISO
PMID:21873635
(PMID:12913096)
RGD PMID:12913096 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Rrlt similar to retinoic acid early transcript 1L IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656
JBrowse link
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:15546957) RGD PMID:15546957 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5586806|PMID:10725737)
Ensembl
RGD
PMID:10725737 GO_REF:0000107 MGI:5586806 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Pomc proopiomelanocortin involved_in ISO (PMID:10670585) RGD PMID:10670585 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:21501162) RGD PMID:21501162 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO (MGI:3611636|PMID:16299293) RGD PMID:16299293 MGI:3611636 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Cd1d1 CD1d1 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2180705|PMID:10201995)
RGD PMID:10201995 PMID:21873635 MGI:2180705, RGD:13792537 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cyrib CYFIP related Rac1 interactor B involved_in ISO (MGI:5432330|PMID:22522492) RGD PMID:22522492 MGI:5432330 NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686
JBrowse link
G Fadd Fas associated via death domain involved_in ISS
ISO
GO_REF:0000024
(MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IDA prevention of heat shock-induced resistance to CTL-mediated killing RGD PMID:10679071 RGD:1298959 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:8871636 RGD:10059395 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:1674604), (PMID:2204066) RGD PMID:1674604 PMID:2204066 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B involved_in ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like acts_upstream_of_or_within ISO MGI:3701255 (MGI:3611636|PMID:16299293), (MGI:3700863|PMID:16461341), (MGI:3700871|PMID:16476767), (MGI:52901|PMID:8464890) RGD PMID:8464890 PMID:16299293 PMID:16461341 PMID:16476767 MGI:3611636 MGI:3700863 MGI:3700871 MGI:52901
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:3042190 (MGI:3040567|PMID:14761980) RGD PMID:14761980 MGI:3040567 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (MGI:55923|PMID:6233370) RGD PMID:6233370 MGI:55923 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 involved_in IDA
ISO
(PMID:2420472) RGD PMID:2420472 PMID:11773898 RGD:2313503 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 acts_upstream_of_or_within
involved_in
ISO (MGI:50291|PMID:1538753)
(PMID:25631937)
RGD PMID:1538753 PMID:25631937 MGI:50291 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:23851683) RGD PMID:23851683 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in
acts_upstream_of_or_within
ISO (PMID:25631937)
(MGI:50291|PMID:1538753)
RGD PMID:1538753 PMID:25631937 MGI:50291 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Stx7 syntaxin 7 involved_in ISO
IEA
(PMID:21438968)
GO_REF:0000107
RGD
Ensembl
PMID:21438968 GO_REF:0000107 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in
ISO
IEA
IDA
(MGI:3611636|PMID:16299293), (MGI:50291|PMID:1538753)
GO_REF:0000107
PMID:1758495
RGD
Ensembl
PMID:1538753 PMID:16299293 PMID:1758495 GO_REF:0000107 MGI:3611636 MGI:50291, RGD:1299069 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329
JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA
(PMID:31959982)
GO_REF:0000107
RGD
Ensembl
PMID:31959982 GO_REF:0000107 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G Slc22a13l1 solute carrier family 22 member 13-like 1 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:118,958,209...118,972,614
Ensembl chr 8:118,961,000...118,966,046
JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec2d C-type lectin domain family 2, member D acts_upstream_of_or_within ISO MGI:107539 (MGI:2682492|PMID:12858173), (MGI:3041277|PMID:14990792), (MGI:3849756|PMID:19535641) RGD PMID:12858173 PMID:14990792 PMID:19535641 MGI:2682492 MGI:3041277 MGI:3849756 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 involved_in ISO (PMID:18502829), (PMID:2784569), (PMID:8046333) RGD PMID:2784569 PMID:8046333 PMID:18502829 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572 PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572 PMID:25631937 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Serpinb3a serpin family B member 3A involved_in ISO (PMID:21857942) RGD PMID:21857942 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2a Fc gamma receptor 2A IMP RGD PMID:16482158 RGD:2293335 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klrb1 killer cell lectin like receptor B1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:162,456,294...162,474,989
Ensembl chr 4:162,456,294...162,474,989
JBrowse link
G Klrb1a killer cell lectin-like receptor subfamily B, member 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675
JBrowse link
G Klrb1b killer cell lectin-like receptor subfamily B member 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:161,949,061...161,961,505
Ensembl chr 4:161,890,577...161,961,675
JBrowse link
G Klrb1c killer cell lectin like receptor B1C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:162,380,773...162,394,688
Ensembl chr 4:162,381,602...162,393,786
JBrowse link
G Lep leptin involved_in ISS
ISO
GO_REF:0000024
(PMID:12504075)
UniProt
RGD
PMID:12504075 GO_REF:0000024 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Nkr-p1c killer cell lectin-like receptor subfamily B member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 involved_in ISO (PMID:11062502) RGD PMID:11062502 NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243
JBrowse link
regulation of neutrophil mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnase1 deoxyribonuclease 1 involved_in ISS
ISO
PMID:29191910
(MGI:6094744|PMID:29191910)
RGD PMID:29191910 PMID:29191910 MGI:6094744, RGD:13464261 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 involved_in ISS
ISO
PMID:29191910
(MGI:6094744|PMID:29191910)
RGD PMID:29191910 PMID:29191910 MGI:6094744, RGD:13464261 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317
JBrowse link
regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl6 C-X-C motif chemokine ligand 6 acts_upstream_of_or_within ISO MGI:4819800 (MGI:4819434|PMID:20643340) RGD PMID:20643340 MGI:4819434 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO (PMID:22473704) RGD PMID:22473704 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q61160 (MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadm1 cell adhesion molecule 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:3689781|PMID:15811952)
(PMID:15811952)
HGNC
RGD
PMID:15811952 PMID:21873635 GO_REF:0000024 MGI:3689781, RGD:13792537 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:12913096)
PMID:21873635
RGD PMID:12913096 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (MGI:2450811|PMID:12645935) RGD PMID:12645935 MGI:2450811 NCBI chr 1:1,694,255...1,716,160 JBrowse link
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nectin2 nectin cell adhesion molecule 2 involved_in IBA
ISO
PMID:21873635
(PMID:15039383)
RGD PMID:15039383 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:15039383) RGD PMID:15039383 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    cellular process 18695
      regulation of cellular process 12438
        regulation of cell killing 125
          regulation of leukocyte mediated cytotoxicity 98
            negative regulation of leukocyte mediated cytotoxicity + 29
            positive regulation of leukocyte mediated cytotoxicity + 67
            regulation of T cell mediated cytotoxicity + 35
            regulation of antibody-dependent cellular cytotoxicity + 3
            regulation of microglial cell mediated cytotoxicity + 5
            regulation of natural killer cell mediated cytotoxicity + 63
            regulation of neutrophil mediated cytotoxicity + 7
Path 2
Term Annotations click to browse term
  biological_process 20099
    biological regulation 13928
      regulation of biological process 13160
        regulation of immune system process 1540
          regulation of immune effector process 428
            regulation of leukocyte mediated immunity 271
              regulation of leukocyte mediated cytotoxicity 98
                negative regulation of leukocyte mediated cytotoxicity + 29
                positive regulation of leukocyte mediated cytotoxicity + 67
                regulation of T cell mediated cytotoxicity + 35
                regulation of antibody-dependent cellular cytotoxicity + 3
                regulation of microglial cell mediated cytotoxicity + 5
                regulation of natural killer cell mediated cytotoxicity + 63
                regulation of neutrophil mediated cytotoxicity + 7
paths to the root