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ONTOLOGY REPORT - ANNOTATIONS


Term:liver development
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Accession:GO:0001889 term browser browse the term
Definition:The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.


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liver development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase ISO RGD PMID:10513626 RGD:2301023 NCBI chr26:4,852,582...4,903,329
Ensembl chr26:4,452,371...4,961,436
JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain acts_upstream_of_or_within ISO (MGI:3692159|PMID:16121256) MGI PMID:16121256 MGI:3692159 NCBI chr 6:70,852,223...70,881,979
Ensembl chr 6:70,853,061...70,878,668
JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 ISO RGD PMID:5166591 RGD:2326169 NCBI chr 5:24,361,301...24,379,807
Ensembl chr 5:24,361,301...24,379,812
JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 ISO RGD PMID:5166591 RGD:2326169 NCBI chr 1:49,011,665...49,029,368
Ensembl chr 1:49,011,706...49,029,327
JBrowse link
G ACO1 aconitase 1 ISO RGD PMID:755797 RGD:11552585 NCBI chr11:49,699,072...49,758,783
Ensembl chr11:49,699,109...49,923,257
JBrowse link
G ACO2 aconitase 2 ISO RGD PMID:755797 RGD:11552585 NCBI chr10:23,742,284...23,798,580
Ensembl chr10:23,742,333...23,798,498
JBrowse link
G ADA adenosine deaminase acts_upstream_of_or_within ISO (MGI:72798|PMID:7731963)
(MGI:74163|PMID:7670465)
MGI PMID:7670465 PMID:7731963 MGI:72798 MGI:74163 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:8408243 RGD:8548535 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G AFP alpha fetoprotein ISO RGD PMID:16822301 RGD:2292045 NCBI chr13:62,182,876...62,203,414
Ensembl chr13:62,053,814...62,294,709
JBrowse link
G AHR aryl hydrocarbon receptor involved_in ISO (MGI:1889403|PMID:10973493), (MGI:3794480|PMID:16443691), (MGI:72762|PMID:7732381), (MGI:81320|PMID:8692887) DFLAT PMID:7732381 PMID:8692887 PMID:10973493 PMID:16443691 MGI:1889403 MGI:3794480 MGI:72762 MGI:81320 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444
JBrowse link
G AK2 adenylate kinase 2 ISO RGD PMID:5123889 RGD:5490208 NCBI chr 2:68,342,769...68,371,769
Ensembl chr 2:68,350,057...68,371,090
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 ISO RGD PMID:14729401 RGD:1643117 NCBI chr 1:84,940,411...84,994,789
Ensembl chr 1:84,940,411...84,994,789
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 ISO RGD PMID:14729401 RGD:1643117 NCBI chr30:23,074,432...23,170,374
Ensembl chr30:23,074,432...23,340,030
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO RGD PMID:16291827 RGD:2300311 NCBI chr26:9,319,109...9,361,021 JBrowse link
G ALDH9A1 aldehyde dehydrogenase 9 family member A1 ISO RGD PMID:19150623 RGD:2313411 NCBI chr38:17,644,464...17,664,462
Ensembl chr38:17,644,459...17,663,886
JBrowse link
G ALDOB aldolase, fructose-bisphosphate B ISO RGD PMID:8641049 RGD:2313428 NCBI chr11:58,150,621...58,166,266
Ensembl chr11:58,150,967...58,176,319
JBrowse link
G ARF6 ADP ribosylation factor 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3653957|PMID:16880525) Ensembl
MGI
PMID:16880525 GO_REF:0000107 MGI:3653957 NCBI chr 8:26,445,407...26,449,430
Ensembl chr 8:26,445,647...26,525,530
JBrowse link
G ARG1 arginase 1 ISO RGD PMID:8690412 RGD:4144072 NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305
JBrowse link
G ASL argininosuccinate lyase ISO DNA:increased methylation:5' utr RGD PMID:9535537 PMID:10473900 RGD:1599266 RGD:1599268 NCBI chr 6:768,522...779,144
Ensembl chr 6:730,358...779,424
JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) ISO RGD PMID:237754 RGD:2316008 NCBI chr14:22,718,020...22,734,109
Ensembl chr14:22,718,042...22,734,054
JBrowse link
G ASS1 argininosuccinate synthase 1 ISO RGD PMID:9395312 PMID:10473900 RGD:1599266 RGD:4139912 NCBI chr 9:53,425,228...53,478,007
Ensembl chr 9:53,425,448...53,477,904
JBrowse link
G ATF2 activating transcription factor 2 involved_in ISO (MGI:3719954|PMID:17699753) MGI PMID:17699753 MGI:3719954 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292
JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (MGI:3587473|PMID:15866887) MGI PMID:15866887 MGI:3587473 NCBI chr20:6,916,354...7,154,849
Ensembl chr20:6,916,515...7,154,800
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta ISO RGD PMID:8420961 RGD:13792579 NCBI chr10:870,405...876,937
Ensembl chr10:870,392...909,161
JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:25349135 RGD:11341669 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G BAAT bile acid-CoA:amino acid N-acyltransferase ISO RGD PMID:7575455 RGD:69770 NCBI chr11:58,102,057...58,116,750
Ensembl chr11:58,102,592...58,109,389
JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 ISO RGD PMID:2806552 RGD:4105456 NCBI chr33:30,407,021...30,422,735
Ensembl chr33:30,406,338...30,436,366
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:14160653 RGD:2303538 NCBI chr17:21,198,839...21,221,897
Ensembl chr17:21,197,826...21,221,635
JBrowse link
G CADM1 cell adhesion molecule 1 ISO RGD PMID:17326163 RGD:2289097 NCBI chr 5:17,865,317...18,190,855
Ensembl chr 5:17,864,453...18,194,694
JBrowse link
G CAST calpastatin ISO RGD PMID:16871587 RGD:5683869 NCBI chr 3:12,920,514...13,031,974
Ensembl chr 3:12,922,453...13,031,959
JBrowse link
G CCND1 cyclin D1 ISO RGD PMID:15809057 RGD:1582338 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005
JBrowse link
G CCND2 cyclin D2 ISO RGD PMID:15809057 RGD:1582338 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255
JBrowse link
G CCNE1 cyclin E1 ISO RGD PMID:15809057 RGD:1582338 NCBI chr 1:121,688,622...121,697,533
Ensembl chr 1:121,688,796...121,697,649
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (MGI:6284072|PMID:30635284) UniProt PMID:30635284 MGI:6284072 NCBI chr 9:24,276,660...24,286,273
Ensembl chr 9:24,276,768...24,286,272
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO RGD PMID:11042273 RGD:7248763 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CEBPA CCAAT enhancer binding protein alpha acts_upstream_of_or_within
involved_in
ISO (MGI:3688957|PMID:17021047)
(MGI:83240|PMID:8798745)
RGD
MGI
UniProt
PMID:8798745 PMID:16172914 PMID:17021047 MGI:3688957 MGI:83240 RGD:1625368 NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO RGD PMID:1377818 RGD:69946 NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656
JBrowse link
G CEBPG CCAAT enhancer binding protein gamma involved_in ISO PMID:1377818 UniProt PMID:1377818 RGD:69946 NCBI chr 1:118,777,110...118,784,397
Ensembl chr 1:118,778,224...118,778,667
JBrowse link
G CIT citron rho-interacting serine/threonine kinase ISO RGD PMID:12411428 RGD:628497 NCBI chr26:15,721,500...15,885,133
Ensembl chr26:15,723,690...15,884,343
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3847632|PMID:17644732) Ensembl
MGI
PMID:17644732 GO_REF:0000107 MGI:3847632 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995
JBrowse link
G COBL cordon-bleu WH2 repeat protein acts_upstream_of_or_within ISO (PMID:7586755) BHF-UCL PMID:7586755 NCBI chr18:2,206,957...2,386,333
Ensembl chr18:2,208,260...2,459,206
JBrowse link
G CP ceruloplasmin ISO RGD PMID:2332446 RGD:728241 NCBI chr23:43,969,297...44,033,226
Ensembl chr23:43,969,435...44,030,369
JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO RGD PMID:8690412 RGD:4144072 NCBI chr37:18,308,164...18,428,487
Ensembl chr37:18,143,986...18,427,697
JBrowse link
G CTNNB1 catenin beta 1 ISO RGD PMID:17236583 RGD:1599633 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:12162855 RGD:727721 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
JBrowse link
G DBP D-box binding PAR bZIP transcription factor ISO RGD PMID:2331750 RGD:727680 NCBI chr 1:107,675,138...107,681,246
Ensembl chr 1:107,675,477...107,681,204
JBrowse link
G DDX39B DExD-box helicase 39B ISO RGD PMID:1618789 RGD:632224 NCBI chr12:1,032,377...1,044,465
Ensembl chr12:1,032,368...1,044,492
JBrowse link
G DUT deoxyuridine triphosphatase ISO RGD PMID:11121581 RGD:5133681 NCBI chr30:14,572,766...14,585,621
Ensembl chr30:14,572,602...14,585,530
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:12454858 RGD:2289959 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G ELK1 ETS transcription factor ELK1 acts_upstream_of_or_within ISO (MGI:6472092|PMID:31877385) MGI PMID:31877385 MGI:6472092 NCBI chr  X:41,256,205...41,270,656
Ensembl chr  X:41,257,482...41,270,776
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:10231554 RGD:13204733 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718
JBrowse link
G EPHX1 epoxide hydrolase 1 ISO RGD PMID:2469391 RGD:4889418 NCBI chr 7:38,964,319...39,004,902
Ensembl chr 7:38,964,338...38,999,238
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:12454858 RGD:2289959 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294
JBrowse link
G FOXM1 forkhead box M1 acts_upstream_of_or_within ISO (MGI:3522012|PMID:15531365) MGI PMID:15531365 MGI:3522012 NCBI chr27:41,894,605...41,905,656
Ensembl chr27:41,894,672...41,905,663
JBrowse link
G FPGS folylpolyglutamate synthase ISO RGD PMID:1435744 RGD:2315102 NCBI chr 9:55,590,092...55,612,639
Ensembl chr 9:55,585,970...55,599,028
JBrowse link
G FSCN1 fascin actin-bundling protein 1 ISO RGD PMID:18855019 RGD:2317768 NCBI chr 6:12,360,849...12,370,906
Ensembl chr 6:12,354,599...12,370,808
JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (MGI:3575862|PMID:15767668) MGI PMID:15767668 MGI:3575862 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 ISO RGD PMID:3996734 RGD:2302171 NCBI chr 8:28,992,173...29,005,511
Ensembl chr 8:28,993,227...29,005,435
JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:3525024|PMID:15578515) MGI PMID:15578515 MGI:3525024
G HGF hepatocyte growth factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3653957|PMID:16880525) Ensembl
MGI
PMID:16880525 GO_REF:0000107 MGI:3653957 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263
JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:1855906|PMID:10804184), (MGI:3703395|PMID:16364283)
(MGI:1891782|PMID:11027604)
(MGI:3487182|PMID:15459110)
MGI PMID:10804184 PMID:11027604 PMID:15459110 PMID:16364283 MGI:1855906 MGI:1891782 MGI:3487182 MGI:3703395 NCBI chr28:7,057,379...7,063,326
Ensembl chr28:7,057,283...7,063,330
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within ISO (MGI:79044|PMID:8557196) MGI PMID:8557196 MGI:79044 NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152
JBrowse link
G HMBS hydroxymethylbilane synthase ISO RGD PMID:971328 RGD:25394583 NCBI chr 5:14,767,306...14,775,205
Ensembl chr 5:14,767,666...14,775,082
JBrowse link
G HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase ISO RGD PMID:13990 RGD:2326149 NCBI chr 2:75,688,736...75,703,095
Ensembl chr 2:75,688,827...75,702,965
JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO RGD PMID:5166591 RGD:2326169 NCBI chr 4:66,633,706...66,654,005
Ensembl chr 4:66,633,572...66,652,196
JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO RGD PMID:8620869 RGD:2326125 NCBI chr17:56,679,942...56,698,521
Ensembl chr17:56,680,301...56,698,419
JBrowse link
G HNF1A HNF1 homeobox A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1202489|PMID:9566924) Ensembl
MGI
PMID:9566924 GO_REF:0000107 MGI:1202489 NCBI chr26:16,805,690...16,826,065
Ensembl chr26:16,805,690...16,824,790
JBrowse link
G HNF1B HNF1 homeobox B acts_upstream_of_or_within ISO (MGI:3807614|PMID:18635606) MGI PMID:18635606 MGI:3807614 NCBI chr 9:37,437,992...37,493,200
Ensembl chr 9:37,438,583...37,492,993
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D ISO RGD PMID:20102719 RGD:10042969 NCBI chr32:6,323,444...6,341,238
Ensembl chr32:6,323,469...6,341,166
JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:16488668 RGD:10002779 NCBI chr 1:75,499,334...75,511,525
Ensembl chr 1:75,499,393...75,511,425
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO RGD PMID:2581126 RGD:14694813 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717
JBrowse link
G IFT88 intraflagellar transport 88 acts_upstream_of_or_within ISO (MGI:2155922|PMID:11773599), (MGI:892192|PMID:9176412) MGI PMID:9176412 PMID:11773599 MGI:2155922 MGI:892192 NCBI chr25:17,414,965...17,551,405
Ensembl chr25:17,414,965...17,551,266
JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO RGD PMID:12127995 RGD:2311626 NCBI chr 1:49,161,551...49,262,260
Ensembl chr 1:49,161,444...49,262,277
JBrowse link
G INSR insulin receptor ISO RGD PMID:6364984 RGD:14701029 NCBI chr20:52,017,261...52,136,061
Ensembl chr20:52,021,887...52,136,046
JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1096257|PMID:9376320) MGI
Ensembl
PMID:9376320 GO_REF:0000107 MGI:1096257 NCBI chr35:14,476,656...14,737,535
Ensembl chr35:14,445,914...14,736,158
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (MGI:1338596|PMID:10352021) MGI PMID:10352021 MGI:1338596 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G KLF1 Kruppel like factor 1 acts_upstream_of_or_within ISO (MGI:73364|PMID:7753194) MGI PMID:7753194 MGI:73364 NCBI chr20:49,295,097...49,298,668
Ensembl chr20:49,295,195...49,298,602
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:1526114 RGD:11060153 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LIPC lipase C, hepatic type ISO RGD PMID:11004003 RGD:2307448 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037
JBrowse link
G LOC480491 GTP:AMP phosphotransferase AK3, mitochondrial ISO RGD PMID:5123889 RGD:5490208 NCBI chr 9:10,282,452...10,283,479 JBrowse link
G LOC485869 lipopolysaccharide binding protein ISO RGD PMID:20978830 RGD:9685195 NCBI chr24:26,810,369...26,833,515
Ensembl chr24:26,809,843...26,833,434
JBrowse link
G LOC607149 cyclic AMP-dependent transcription factor ATF-7 involved_in ISO (MGI:3719954|PMID:17699753) MGI PMID:17699753 MGI:3719954 NCBI chr27:1,617,466...1,711,356
Ensembl chr27:1,617,289...1,706,637
JBrowse link
G LOC609557 cryptic protein acts_upstream_of_or_within ISO (MGI:1346729|PMID:10521397) MGI PMID:10521397 MGI:1346729 NCBI chr19:20,318,937...20,384,369 JBrowse link
G LSR lipolysis stimulated lipoprotein receptor involved_in ISO (MGI:3052428|PMID:15265030) HGNC-UCL PMID:15265030 MGI:3052428 NCBI chr 1:117,319,672...117,333,426
Ensembl chr 1:117,319,658...117,333,419
JBrowse link
G MAN2A1 mannosidase alpha class 2A member 1 acts_upstream_of_or_within ISO (MGI:3652665|PMID:16754854) MGI PMID:16754854 MGI:3652665 NCBI chr 3:2,340,392...2,477,458
Ensembl chr 3:2,330,959...2,488,393
JBrowse link
G MED1 mediator complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2682174|PMID:14500757) Ensembl
MGI
PMID:14500757 GO_REF:0000107 MGI:2682174 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:76093|PMID:7651534)
GO_Central
MGI
RGD
PMID:7651534 PMID:8506951 PMID:21873635 MGI:76093 RGD:2317549 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027
JBrowse link
G MPST mercaptopyruvate sulfurtransferase ISO RGD PMID:6573924 RGD:9685558 NCBI chr10:27,465,007...27,469,788
Ensembl chr10:27,443,865...27,469,554
JBrowse link
G MRTFB myocardin related transcription factor B acts_upstream_of_or_within ISO (MGI:3695837|PMID:17183527) MGI PMID:17183527 MGI:3695837 NCBI chr 6:28,902,749...29,113,448
Ensembl chr 6:28,918,350...29,098,220
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:66069|PMID:7926784) MGI PMID:7926784 MGI:66069 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382
JBrowse link
G NODAL nodal growth differentiation factor acts_upstream_of_or_within ISO (MGI:2155575|PMID:11311163) MGI PMID:11311163 MGI:2155575 NCBI chr 4:21,366,828...21,374,623
Ensembl chr 4:21,367,583...21,375,151
JBrowse link
G NOTCH1 notch receptor 1 acts_upstream_of_or_within ISO (MGI:3045664|PMID:15226394) MGI PMID:15226394 MGI:3045664 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G NOTCH2 notch receptor 2 acts_upstream_of_or_within ISO (MGI:5616947|PMID:25446530) MGI PMID:25446530 MGI:5616947 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857
JBrowse link
G NTS neurotensin ISO RGD PMID:8342998 RGD:9743870 NCBI chr15:27,361,002...27,372,232
Ensembl chr15:27,361,002...27,372,232
JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3763866|PMID:17936262) Ensembl
MGI
PMID:17936262 GO_REF:0000107 MGI:3763866 NCBI chr30:18,384,533...18,425,940
Ensembl chr30:18,387,130...18,425,497
JBrowse link
G ONECUT2 one cut homeobox 2 acts_upstream_of_or_within ISO (MGI:3763866|PMID:17936262) MGI PMID:17936262 MGI:3763866 NCBI chr 1:18,428,112...18,486,047
Ensembl chr 1:18,440,172...18,486,048
JBrowse link
G OTC ornithine transcarbamylase ISO RGD PMID:8690412 RGD:4144072 NCBI chr  X:33,130,921...33,200,441
Ensembl chr  X:33,131,040...33,199,595
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in
acts_upstream_of_or_within
ISO PMID:12552133
(PMID:12552133)
HGNC-UCL PMID:12552133 RGD:629554 NCBI chr 5:54,197,211...54,210,724 JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4355651|PMID:19619492) Ensembl
MGI
PMID:19619492 GO_REF:0000107 MGI:4355651 NCBI chr25:11,741,863...11,746,885
Ensembl chr25:11,741,863...11,746,885
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5582991|PMID:24691033) Ensembl
MGI
PMID:24691033 GO_REF:0000107 MGI:5582991 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting acts_upstream_of_or_within ISO (MGI:5441703|PMID:21685914) MGI PMID:21685914 MGI:5441703 NCBI chr 6:38,811,051...38,865,503
Ensembl chr 6:38,837,964...38,865,503
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in
acts_upstream_of_or_within
ISO (PMID:11891195)
(MGI:5441703|PMID:21685914)
UniProt
MGI
PMID:11891195 PMID:21685914 MGI:5441703 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438
JBrowse link
G PKM pyruvate kinase M1/2 ISO RGD PMID:7327170 RGD:2303137 NCBI chr30:35,712,853...35,737,643 JBrowse link
G PRKCSH protein kinase C substrate 80K-H involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5441703|PMID:21685914)
GO_Central
MGI
PMID:21685914 PMID:21873635 MGI:5441703 NCBI chr20:49,905,246...49,916,551
Ensembl chr20:49,905,248...49,916,463
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa acts_upstream_of_or_within ISO (MGI:1306904|PMID:9788960) RGD
MGI
PMID:7660357 PMID:9788960 MGI:1306904 RGD:1299299 NCBI chr19:23,173,626...23,183,634
Ensembl chr19:23,173,635...23,183,563
JBrowse link
G PROS1 protein S ISO RGD PMID:7660357 RGD:1299299 NCBI chr33:1,628,074...1,691,441
Ensembl chr33:1,628,105...1,692,058
JBrowse link
G PROX1 prospero homeobox 1 involved_in ISO (PMID:11789987) RGD
BHF-UCL
PMID:11789987 PMID:16770575 RGD:5133274 NCBI chr 7:11,996,282...12,047,693
Ensembl chr 7:11,996,703...12,044,036
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 ISO RGD PMID:24707720 RGD:9854625 NCBI chr12:2,432,287...2,438,920
Ensembl chr12:2,432,505...2,438,069
JBrowse link
G PTCD2 pentatricopeptide repeat domain 2 acts_upstream_of_or_within ISO (MGI:3829520|PMID:18729827) MGI PMID:18729827 MGI:3829520 NCBI chr 2:55,351,678...55,382,881
Ensembl chr 2:55,351,558...55,382,746
JBrowse link
G PTN pleiotrophin ISO RGD PMID:12057922 RGD:727382 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814
JBrowse link
G QDPR quinoid dihydropteridine reductase ISO RGD PMID:710385 RGD:5128606 NCBI chr 3:62,970,850...62,987,512
Ensembl chr 3:62,970,121...63,028,395
JBrowse link
G RARA retinoic acid receptor alpha ISO RGD PMID:15388488 RGD:2314298 NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459
JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3689241|PMID:17015619) Ensembl
MGI
PMID:17015619 GO_REF:0000107 MGI:3689241 NCBI chr29:4,445,668...4,544,223
Ensembl chr29:4,375,785...4,517,168
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875
JBrowse link
G RGN regucalcin ISO RGD PMID:8794449 PMID:9546611 RGD:9590173 RGD:9590212 NCBI chr  X:40,697,292...40,715,491
Ensembl chr  X:40,698,768...40,715,490
JBrowse link
G RHBDD3 rhomboid domain containing 3 acts_upstream_of_or_within ISO (MGI:5492204|PMID:23610400) MGI PMID:23610400 MGI:5492204 NCBI chr26:22,573,260...22,578,921
Ensembl chr26:22,573,316...22,577,683
JBrowse link
G RPGRIP1L RPGRIP1 like involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3716248|PMID:17558409) Ensembl
MGI
PMID:17558409 GO_REF:0000107 MGI:3716248 NCBI chr 2:62,080,159...62,179,694
Ensembl chr 2:62,080,080...62,178,284
JBrowse link
G RUNX1 RUNX family transcription factor 1 acts_upstream_of_or_within ISO (MGI:3759935|PMID:16174759) MGI PMID:16174759 MGI:3759935 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839
JBrowse link
G RXRA retinoid X receptor alpha ISO RGD PMID:14729401 RGD:1643117 NCBI chr 9:50,525,195...50,575,720
Ensembl chr 9:50,484,567...50,573,119
JBrowse link
G SEC63 SEC63 homolog, protein translocation regulator acts_upstream_of_or_within ISO (MGI:5441703|PMID:21685914) MGI PMID:21685914 MGI:5441703 NCBI chr12:64,983,442...65,028,573 JBrowse link
G SLC25A4 solute carrier family 25 member 4 ISO RGD PMID:9468308 RGD:9681468 NCBI chr16:45,454,660...45,458,606
Ensembl chr16:45,411,810...45,542,162
JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 ISO RGD PMID:15288467 RGD:2303131 NCBI chr27:26,411,008...26,496,174
Ensembl chr27:26,411,010...26,470,989
JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 ISO RGD PMID:15345472 RGD:2316987 NCBI chr21:23,347,593...23,393,480
Ensembl chr21:23,346,070...23,473,831
JBrowse link
G SMAD3 SMAD family member 3 acts_upstream_of_or_within ISO (MGI:3618021|PMID:15183723) MGI PMID:15183723 MGI:3618021 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337
JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (MGI:3610843|PMID:16287714) MGI PMID:16287714 MGI:3610843 NCBI chr20:50,175,489...50,268,865
Ensembl chr20:50,175,687...50,268,836
JBrowse link
G SOD2 superoxide dismutase 2 acts_upstream_of_or_within ISO (MGI:3718142|PMID:17367743) MGI PMID:17367743 MGI:3718142 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G SP1 Sp1 transcription factor acts_upstream_of_or_within ISO (MGI:3717030|PMID:17584888) MGI PMID:17584888 MGI:3717030 NCBI chr27:1,802,587...1,861,187
Ensembl chr27:1,805,184...1,847,226
JBrowse link
G SP3 Sp3 transcription factor acts_upstream_of_or_within ISO (MGI:3717030|PMID:17584888) MGI PMID:17584888 MGI:3717030 NCBI chr36:18,023,750...18,086,995
Ensembl chr36:18,024,627...18,077,587
JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO RGD PMID:8770891 RGD:4892048 NCBI chr34:7,118,814...7,144,828
Ensembl chr34:7,118,814...7,144,828
JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 ISO RGD PMID:9199345 RGD:11039429 NCBI chr 8:43,514,048...43,519,019
Ensembl chr 8:43,514,076...43,518,481
JBrowse link
G STAT5B signal transducer and activator of transcription 5B ISO RGD PMID:17565389 RGD:2291935 NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485
JBrowse link
G TAF10 TATA-box binding protein associated factor 10 acts_upstream_of_or_within ISO (MGI:3806427|PMID:18722179) MGI PMID:18722179 MGI:3806427 NCBI chr21:29,917,941...29,919,347
Ensembl chr21:29,917,947...29,919,330
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in ISO (MGI:2663364|PMID:12773577) BHF-UCL PMID:12773577 MGI:2663364 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121
JBrowse link
G THRA thyroid hormone receptor alpha ISO RGD PMID:17496154 RGD:2314319 NCBI chr 9:22,469,466...22,493,445
Ensembl chr 9:22,468,594...22,493,445
JBrowse link
G TK1 thymidine kinase 1 ISO RGD PMID:995499 RGD:2317236 NCBI chr 9:2,959,450...2,970,908
Ensembl chr 9:2,959,488...2,971,064
JBrowse link
G UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 ISO RGD PMID:18938141 RGD:2317023 NCBI chr25:45,081,655...45,161,584
Ensembl chr25:45,032,130...45,160,941
JBrowse link
G UPB1 beta-ureidopropionase 1 ISO RGD PMID:6870258 RGD:2317093 NCBI chr26:28,194,968...28,225,977
Ensembl chr26:28,195,081...28,225,567
JBrowse link
G UPF2 UPF2 regulator of nonsense mediated mRNA decay acts_upstream_of_or_within ISO (MGI:4821037|PMID:20657840) MGI PMID:20657840 MGI:4821037 NCBI chr 2:24,370,961...24,473,437
Ensembl chr 2:24,371,058...24,472,140
JBrowse link
G UROD uroporphyrinogen decarboxylase ISO RGD PMID:6219675 RGD:4145103 NCBI chr15:15,313,808...15,317,130
Ensembl chr15:15,312,674...15,320,010
JBrowse link
G VWF von Willebrand factor acts_upstream_of_or_within ISO (MGI:70957|PMID:7854452) MGI PMID:7854452 MGI:70957 NCBI chr27:38,834,812...38,972,614
Ensembl chr27:38,833,837...39,320,142
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:15312687) UniProt PMID:15312687 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:1352298|PMID:10652269) UniProt PMID:10652269 MGI:1352298 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5609934|PMID:23117660) Ensembl
MGI
PMID:23117660 GO_REF:0000107 MGI:5609934 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160
JBrowse link
determination of liver left/right asymmetry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC39 coiled-coil domain containing 39 involved_in ISO (PMID:22693285) BHF-UCL PMID:22693285 NCBI chr34:13,915,763...13,959,574
Ensembl chr34:13,905,434...13,959,340
JBrowse link
G CCDC40 coiled-coil domain containing 40 involved_in ISO (PMID:22693285) BHF-UCL PMID:22693285 NCBI chr 9:1,616,029...1,656,043
Ensembl chr 9:1,601,121...1,656,597
JBrowse link
G DNAAF1 dynein axonemal assembly factor 1 involved_in ISO (PMID:19944405) BHF-UCL PMID:19944405 NCBI chr 5:68,184,532...68,205,651
Ensembl chr 5:68,184,532...68,205,656
JBrowse link
G NPHP3 nephrocystin 3 involved_in ISO (PMID:20007846) BHF-UCL PMID:20007846 NCBI chr23:29,662,486...29,703,629
Ensembl chr23:29,645,641...29,703,805
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:21719175) BHF-UCL PMID:21719175 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438
JBrowse link
G ZIC3 Zic family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:107,822,002...107,833,582
Ensembl chr  X:107,821,948...107,833,597
JBrowse link
hepatoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GGT1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chr26:28,301,455...28,315,029 JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:3720549|PMID:17580084) MGI PMID:17580084 MGI:3720549 NCBI chr28:7,057,379...7,063,326
Ensembl chr28:7,057,283...7,063,330
JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3807614|PMID:18635606) Ensembl
MGI
PMID:18635606 GO_REF:0000107 MGI:3807614 NCBI chr 9:37,437,992...37,493,200
Ensembl chr 9:37,438,583...37,492,993
JBrowse link
hepatocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:11668598 PMID:21873635 RGD:2306909 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011
JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO RGD PMID:12939595 RGD:4144098 NCBI chr37:18,308,164...18,428,487
Ensembl chr37:18,143,986...18,427,697
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:17574236 RGD:2306655 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
JBrowse link
G E2F7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chr15:19,856,093...19,895,657
Ensembl chr15:19,857,227...19,895,225
JBrowse link
G E2F8 E2F transcription factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:41,340,410...41,358,261
Ensembl chr21:41,340,969...41,357,206
JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chr26:28,301,455...28,315,029 JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:1891782|PMID:11027604) MGI PMID:11027604 MGI:1891782 NCBI chr28:7,057,379...7,063,326
Ensembl chr28:7,057,283...7,063,330
JBrowse link
G HNF1B HNF1 homeobox B ISO RGD PMID:18286537 RGD:2312718 NCBI chr 9:37,437,992...37,493,200
Ensembl chr 9:37,438,583...37,492,993
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha involved_in IEA
ISO
InterPro
RGD
PMID:19621519 GO_REF:0000002 RGD:12904750 NCBI chr24:31,847,864...31,908,337
Ensembl chr24:31,847,961...31,905,916
JBrowse link
G ITGA2 integrin subunit alpha 2 ISO RGD PMID:16458388 RGD:2307397 NCBI chr 4:62,170,137...62,268,962
Ensembl chr 4:62,170,452...62,268,983
JBrowse link
G KRT18 keratin 18 ISO RGD PMID:24340101 PMID:28941653 RGD:27226712 RGD:27226713 NCBI chr27:2,189,269...2,193,368
Ensembl chr27:2,189,269...2,193,368
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:42,538,858...42,544,200
Ensembl chr24:42,538,882...42,544,198
JBrowse link
G PROX1 prospero homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15232737) Ensembl
BHF-UCL
PMID:15232737 GO_REF:0000107 NCBI chr 7:11,996,282...12,047,693
Ensembl chr 7:11,996,703...12,044,036
JBrowse link
G TAF10 TATA-box binding protein associated factor 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3806427|PMID:18722179) Ensembl
MGI
PMID:18722179 GO_REF:0000107 MGI:3806427 NCBI chr21:29,917,941...29,919,347
Ensembl chr21:29,917,947...29,919,330
JBrowse link
G WNT1 Wnt family member 1 ISO RGD PMID:20413689 RGD:2326223 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060
JBrowse link
hepatocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPB CCAAT enhancer binding protein beta involved_in ISO (MGI:3778721|PMID:10635333) UniProt PMID:10635333 MGI:3778721 RGD:10047310 NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656
JBrowse link
G FGL1 fibrinogen like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:41,161,314...41,191,282
Ensembl chr16:41,161,394...41,179,791
JBrowse link
G IL6 interleukin 6 involved_in ISS UniProt GO_REF:0000024 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G MKI67 marker of proliferation Ki-67 acts_upstream_of_or_within ISO (MGI:5616947|PMID:25446530) MGI PMID:25446530 MGI:5616947 NCBI chr28:36,920,679...36,939,336
Ensembl chr28:36,913,023...36,939,486
JBrowse link
G NOTCH2 notch receptor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5616947|PMID:25446530) Ensembl
MGI
PMID:25446530 GO_REF:0000107 MGI:5616947 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29138817 RGD:15042871 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116
JBrowse link
G PROX1 prospero homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1860507|PMID:10888866) Ensembl
MGI
PMID:10888866 GO_REF:0000107 MGI:1860507 NCBI chr 7:11,996,282...12,047,693
Ensembl chr 7:11,996,703...12,044,036
JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 involved_in ISO (MGI:3778721|PMID:10635333) UniProt PMID:10635333 MGI:3778721 NCBI chr 2:73,497,128...73,533,853
Ensembl chr 2:73,497,473...73,534,378
JBrowse link
G TGFA transforming growth factor alpha involved_in ISO PMID:10635333
(MGI:3778721|PMID:10635333)
UniProt PMID:10635333 MGI:3778721 RGD:10047310 NCBI chr10:68,915,671...68,957,027 JBrowse link
intrahepatic bile duct development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAK cyclin G associated kinase acts_upstream_of_or_within ISO (MGI:5305417|PMID:18434600) MGI PMID:18434600 MGI:5305417 NCBI chr 3:91,575,537...91,630,715
Ensembl chr 3:91,574,751...91,630,663
JBrowse link
G NOTCH2 notch receptor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5616947|PMID:25446530) Ensembl
MGI
PMID:25446530 GO_REF:0000107 MGI:5616947 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857
JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3852603|PMID:19403103) MGI PMID:19403103 MGI:3852603 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
liver morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUL3 cullin 3 acts_upstream_of_or_within ISO (MGI:3713609|PMID:17339333) MGI PMID:17339333 MGI:3713609 NCBI chr25:37,730,903...37,819,851
Ensembl chr25:37,733,229...37,800,886
JBrowse link
G NOTCH2 notch receptor 2 acts_upstream_of_or_within ISO (MGI:5616947|PMID:25446530) MGI PMID:25446530 MGI:5616947 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 acts_upstream_of_or_within ISO (MGI:5298314|PMID:21803851) MGI PMID:21803851 MGI:5298314 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536
JBrowse link
liver regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:8855951 RGD:8548508 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G AFP alpha fetoprotein ISO RGD PMID:2460696 RGD:126848734 NCBI chr13:62,182,876...62,203,414
Ensembl chr13:62,053,814...62,294,709
JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 ISO RGD PMID:6895999 RGD:11035238 NCBI chr  X:46,703,477...46,731,767
Ensembl chr  X:46,703,477...46,723,529
JBrowse link
G ANGPT1 angiopoietin 1 ISO RGD PMID:11549276 RGD:704403 NCBI chr13:8,068,920...8,312,090
Ensembl chr13:8,048,205...8,311,618
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO RGD PMID:11032760 RGD:13782137 NCBI chr 9:47,694,494...47,727,017
Ensembl chr 9:47,695,809...47,727,778
JBrowse link
G AURKA aurora kinase A acts_upstream_of_or_within ISO (PMID:19435814) MGI PMID:19435814 NCBI chr24:41,585,483...41,604,875
Ensembl chr24:41,585,518...41,604,791
JBrowse link
G B9D2 B9 domain containing 2 ISO RGD PMID:25862490 RGD:11073669 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO RGD PMID:21503946 RGD:11531107 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G CCND1 cyclin D1 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005
JBrowse link
G CEBPB CCAAT enhancer binding protein beta involved_in ISO (MGI:1277818|PMID:9727068) UniProt PMID:9727068 MGI:1277818 NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656
JBrowse link
G CFTR CF transmembrane conductance regulator ISO RGD PMID:1378998 RGD:11567227 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977
JBrowse link
G CLDN1 claudin 1 ISO RGD PMID:15826721 RGD:11344894 NCBI chr34:22,303,058...22,319,101
Ensembl chr34:22,303,850...22,319,033
JBrowse link
G CPB2 carboxypeptidase B2 ISO RGD PMID:19386599 RGD:7243112 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO RGD PMID:31953200 RGD:25823179 NCBI chr18:49,136,691...49,190,117
Ensembl chr18:49,136,691...49,190,117
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO RGD PMID:8573159 RGD:11565141 NCBI chr24:20,333,593...20,390,341 JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 ISO RGD PMID:8573159 RGD:11565141 NCBI chr 2:58,361,328...58,441,701
Ensembl chr 2:58,360,838...58,432,371
JBrowse link
G CSNK2B casein kinase 2 beta ISO RGD PMID:8573159 RGD:11565141 NCBI chr12:1,149,467...1,154,417
Ensembl chr12:1,149,548...1,154,418
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:2401457 PMID:20395437 RGD:10395295 RGD:38599218 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (MGI:5637451|PMID:25477280) MGI PMID:25477280 MGI:5637451 NCBI chr 9:20,271,729...20,292,918
Ensembl chr 9:20,264,552...20,290,712
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (MGI:5637451|PMID:25477280) MGI PMID:25477280 MGI:5637451 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:10632538 RGD:8662889 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FGA fibrinogen alpha chain ISO RGD PMID:3817019 RGD:728788 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:16162160 RGD:10402121 NCBI chr25:11,231,958...11,410,379
Ensembl chr25:11,231,737...11,407,621
JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO RGD PMID:24880092 RGD:9685725 NCBI chr 6:38,948,927...38,951,300
Ensembl chr 6:38,949,484...38,951,703
JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chr26:28,301,455...28,315,029 JBrowse link
G GLI1 GLI family zinc finger 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5515698|PMID:23740243) Ensembl
MGI
RGD
PMID:22024090 PMID:22790641 PMID:23740243 GO_REF:0000107 MGI:5515698 RGD:12832760 RGD:12911223 NCBI chr10:1,565,306...1,575,971
Ensembl chr10:1,565,244...1,575,982
JBrowse link
G GLI3 GLI family zinc finger 3 ISO RGD PMID:22024090 RGD:12911223 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132
JBrowse link
G HAMP hepcidin antimicrobial peptide ISO RGD PMID:22364558 RGD:8694419 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619
JBrowse link
G HFE homeostatic iron regulator ISO RGD PMID:22364558 RGD:8694419 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413
JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:24815159 RGD:10755743 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773
JBrowse link
G HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 ISO RGD PMID:16081591 RGD:1599972 NCBI chr 6:17,220,006...17,223,985
Ensembl chr 6:17,219,574...17,223,114
JBrowse link
G IHH Indian hedgehog signaling molecule ISO RGD PMID:22024090 RGD:12911223 NCBI chr37:25,616,942...25,622,989 JBrowse link
G IL10 interleukin 10 ISO RGD PMID:11813605 RGD:11049526 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:24412291 RGD:14696652 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL6 interleukin 6 involved_in ISS UniProt GO_REF:0000024 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G INSR insulin receptor ISO RGD PMID:23633480 RGD:9685423 NCBI chr20:52,017,261...52,136,061
Ensembl chr20:52,021,887...52,136,046
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:24814243 RGD:13793384 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198
JBrowse link
G KLKB1 kallikrein B1 ISO RGD PMID:9869390 RGD:7297052 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:3335218 RGD:10059623 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
G NCL nucleolin ISO RGD PMID:7490256 RGD:9686389 NCBI chr25:43,330,524...43,384,909
Ensembl chr25:43,330,799...43,384,258
JBrowse link
G NFKBIA NFKB inhibitor alpha ISO RGD PMID:24512945 RGD:10413865 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:14635188 RGD:11534994 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29138817 RGD:15042871 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116
JBrowse link
G PCNA proliferating cell nuclear antigen ISO RGD PMID:7906221 RGD:10448980 NCBI chr24:16,478,774...16,485,992
Ensembl chr24:16,478,769...16,484,992
JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 ISO RGD PMID:191106 RGD:11554175 NCBI chr10:56,478,771...56,520,992
Ensembl chr10:56,478,680...56,520,967
JBrowse link
G POU2F1 POU class 2 homeobox 1 ISO RGD PMID:1841628 RGD:9743904 NCBI chr 7:30,975,303...31,162,288
Ensembl chr 7:30,986,181...31,162,246
JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO RGD PMID:15837430 RGD:2299961 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:15837430 RGD:2299961 NCBI chr 8:3,248,349...3,257,567
Ensembl chr 8:3,248,404...3,257,456
JBrowse link
G PTCH1 patched 1 ISO RGD PMID:22024090 RGD:12911223 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662
JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 ISO RGD PMID:7591957 RGD:1599982 NCBI chr11:64,486,293...64,595,416
Ensembl chr11:64,489,446...64,630,004
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:9015365 RGD:10003155 NCBI chr17:63,725,812...63,795,359
Ensembl chr17:63,726,248...63,746,881
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:22227930 RGD:9850085 NCBI chr27:6,993,452...7,030,372
Ensembl chr27:6,993,452...7,017,316
JBrowse link
G RGN regucalcin ISO RGD PMID:7759556 RGD:9590197 NCBI chr  X:40,697,292...40,715,491
Ensembl chr  X:40,698,768...40,715,490
JBrowse link
G RPL10 ribosomal protein L10 ISO RGD PMID:6121318 RGD:11038709 NCBI chr  X:122,098,020...122,100,719
Ensembl chr  X:122,098,020...122,100,719
JBrowse link
G RPL13 ribosomal protein L13 ISO RGD PMID:6121318 RGD:11038709 NCBI chr 5:63,978,424...63,980,698
Ensembl chr 5:63,978,424...63,980,603
JBrowse link
G RPL18 ribosomal protein L18 ISO RGD PMID:6121318 RGD:11038709 NCBI chr 1:107,690,021...107,694,586
Ensembl chr 1:107,688,074...107,694,596
JBrowse link
G RPL19 ribosomal protein L19 ISO RGD PMID:6121318 RGD:11038709 NCBI chr 9:23,171,508...23,175,656
Ensembl chr 9:23,171,508...23,175,656
JBrowse link
G RPL30 ribosomal protein L30 ISO RGD PMID:6121318 RGD:11038709 NCBI chr13:301,263...304,854 JBrowse link
G RPL7 ribosomal protein L7 ISO RGD PMID:6121318 RGD:11038709 NCBI chr29:21,881,048...21,884,401
Ensembl chr29:21,881,044...21,884,731
JBrowse link
G RPS15 ribosomal protein S15 ISO RGD PMID:2829897 RGD:11040696 NCBI chr20:57,406,544...57,407,015
Ensembl chr20:57,406,545...57,413,421
JBrowse link
G RPS16 ribosomal protein S16 ISO RGD PMID:6121318 RGD:11038709 NCBI chr 1:113,795,239...113,798,380
Ensembl chr 1:113,644,100...113,828,488
JBrowse link
G RPS24 ribosomal protein S24 ISO RGD PMID:7612009 RGD:11041663 NCBI chr 4:27,886,872...27,893,145
Ensembl chr 4:27,877,075...27,908,806
JBrowse link
G SHH sonic hedgehog signaling molecule ISO RGD PMID:22790641 RGD:12832760 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903
JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 ISO RGD PMID:23633480 RGD:9685423 NCBI chr 9:32,692,517...32,696,325
Ensembl chr 9:32,694,073...32,696,285
JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 ISO RGD PMID:7686911 RGD:729792 NCBI chr 8:43,514,048...43,519,019
Ensembl chr 8:43,514,076...43,518,481
JBrowse link
G SULF2 sulfatase 2 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr24:34,732,000...34,850,347
Ensembl chr24:34,732,037...34,828,569
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:9178702 RGD:14995465 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TYMS thymidylate synthetase ISO RGD PMID:2707640 RGD:2317422 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747
JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:19104935 RGD:7204431 NCBI chr21:24,304,410...24,311,392
Ensembl chr21:24,304,457...24,311,128
JBrowse link
G VTN vitronectin ISO RGD PMID:10988248 RGD:10003090 NCBI chr 9:42,617,860...42,620,825
Ensembl chr 9:42,614,941...42,630,864
JBrowse link
G VWF von Willebrand factor ISO RGD PMID:12217600 RGD:727737 NCBI chr27:38,834,812...38,972,614
Ensembl chr27:38,833,837...39,320,142
JBrowse link
G WDR35 WD repeat domain 35 ISO RGD PMID:18472094 RGD:11553927 NCBI chr17:14,976,662...15,034,918
Ensembl chr17:14,977,457...15,034,748
JBrowse link
negative regulation of hepatocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FRZB frizzled related protein acts_upstream_of_or_within ISO (MGI:4356222|PMID:19562671) MGI PMID:19562671 MGI:4356222 NCBI chr36:25,884,557...25,907,436
Ensembl chr36:25,884,557...25,907,369
JBrowse link
negative regulation of hepatocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO PMID:15467833
(MGI:3057041|PMID:15467833)
UniProt PMID:15467833 MGI:3057041 RGD:11059592 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830
JBrowse link
G CPB2 carboxypeptidase B2 ISO RGD PMID:19386599 RGD:7243112 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170
JBrowse link
G LIMS1 LIM zinc finger domain containing 1 acts_upstream_of_or_within ISO (MGI:5559100|PMID:24058607) MGI PMID:24058607 MGI:5559100 NCBI chr10:35,192,582...35,339,100 JBrowse link
G LIMS2 LIM zinc finger domain containing 2 acts_upstream_of_or_within ISO (MGI:5559100|PMID:24058607) MGI PMID:24058607 MGI:5559100 NCBI chr19:22,932,251...22,978,437
Ensembl chr19:22,931,779...22,982,765
JBrowse link
positive regulation of hepatocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISO RGD PMID:19229878 RGD:8885195 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G FOXA3 forkhead box A3 ISO RGD PMID:9878541 RGD:2315086 NCBI chr 1:109,749,142...109,757,149
Ensembl chr 1:109,748,926...109,757,006
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,738,333...52,739,962
Ensembl chr 3:52,738,366...52,739,755
JBrowse link
positive regulation of hepatocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:16033771 RGD:11341689 NCBI chr37:10,268,407...10,307,803
Ensembl chr37:10,268,582...10,345,095
JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISO PMID:16756958 UniProt PMID:16756958 RGD:10047366 NCBI chr 2:37,467,431...37,554,770
Ensembl chr 2:37,470,985...37,554,619
JBrowse link
G FGF18 fibroblast growth factor 18 involved_in ISO PMID:16756958 UniProt PMID:16756958 RGD:10047366 NCBI chr 4:40,714,891...40,748,892
Ensembl chr 4:40,715,060...40,748,518
JBrowse link
G HPN hepsin involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:117,486,308...117,503,127
Ensembl chr 1:117,486,340...117,502,583
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:24412291 RGD:14696652 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:24814243 RGD:13793384 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198
JBrowse link
G LOC491316 midkine involved_in ISO (MGI:3606557|PMID:15482347) UniProt PMID:15482347 MGI:3606557 NCBI chr 9:55,100,491...55,101,081 JBrowse link
G MED1 mediator complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3719773|PMID:17438330) Ensembl
MGI
PMID:17438330 GO_REF:0000107 MGI:3719773 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349
JBrowse link
G PTN pleiotrophin involved_in ISO (MGI:3606557|PMID:15482347) RGD
UniProt
PMID:15482347 PMID:16226713 MGI:3606557 RGD:9834996 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814
JBrowse link
G RTN4 reticulon 4 involved_in ISO (MGI:6282933|PMID:23299899) UniProt PMID:23299899 MGI:6282933 NCBI chr10:55,884,452...55,954,476
Ensembl chr10:55,885,125...55,936,574
JBrowse link
G TNF tumor necrosis factor ISO with PCB 126 or TCDD RGD PMID:9111198 PMID:17557910 RGD:14995469 RGD:14995481 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,247,432...30,262,992
Ensembl chr 1:30,251,059...30,261,001
JBrowse link
G WNT3A Wnt family member 3A acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:1352298|PMID:10652269) UniProt PMID:10652269 MGI:1352298 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105
JBrowse link
regulation of hepatocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI1 GLI family zinc finger 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5515698|PMID:23740243) Ensembl
MGI
PMID:23740243 GO_REF:0000107 MGI:5515698 NCBI chr10:1,565,306...1,575,971
Ensembl chr10:1,565,244...1,575,982
JBrowse link
G IFNG interferon gamma ISO RGD PMID:15799032 RGD:8142374 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G PLAU plasminogen activator, urokinase ISO RGD PMID:17587687 RGD:6484147 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851
JBrowse link
G SULF2 sulfatase 2 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr24:34,732,000...34,850,347
Ensembl chr24:34,732,037...34,828,569
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13863
    developmental process 6133
      anatomical structure development 5707
        animal organ development 3764
          gland development 606
            liver development 244
              determination of liver left/right asymmetry 6
              hepatoblast differentiation 3
              hepatocyte differentiation + 19
              intrahepatic bile duct development 3
              liver morphogenesis + 33
              liver regeneration 72
              liver trabecula formation 0
Path 2
Term Annotations click to browse term
  biological_process 13863
    developmental process 6133
      anatomical structure development 5707
        multicellular organism development 5206
          system development 4895
            animal organ development 3764
              gland development 606
                liver development 244
                  determination of liver left/right asymmetry 6
                  hepatoblast differentiation 3
                  hepatocyte differentiation + 19
                  intrahepatic bile duct development 3
                  liver morphogenesis + 33
                  liver regeneration 72
                  liver trabecula formation 0
paths to the root