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ONTOLOGY REPORT - ANNOTATIONS


Term:liver development
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Accession:GO:0001889 term browser browse the term
Definition:The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.


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liver development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase ISO RGD PMID:10513626 RGD:2301023 NCBI chr12:122,660,621...122,737,421
Ensembl chr12:126,942,340...127,019,372
JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain acts_upstream_of_or_within ISO (MGI:3692159|PMID:16121256) MGI PMID:16121256 MGI:3692159 NCBI chr 1:74,939,477...74,978,815
Ensembl chr 1:76,911,763...76,950,840
JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 ISO RGD PMID:5166591 RGD:2326169 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787
JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 ISO RGD PMID:5166591 RGD:2326169 NCBI chr 6:157,644,894...157,661,965
Ensembl chr 6:162,656,497...162,673,606
JBrowse link
G ACO1 aconitase 1 ISO RGD PMID:755797 RGD:11552585 NCBI chr 9:32,157,763...32,225,116
Ensembl chr 9:32,967,993...33,035,177
JBrowse link
G ACO2 aconitase 2 ISO RGD PMID:755797 RGD:11552585 NCBI chr22:22,363,178...22,423,041
Ensembl chr22:40,450,276...40,510,200
JBrowse link
G ADA adenosine deaminase acts_upstream_of_or_within ISO (MGI:74163|PMID:7670465)
(MGI:72798|PMID:7731963)
MGI PMID:7670465 PMID:7731963 MGI:72798 MGI:74163 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:8408243 RGD:8548535 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G AFP alpha fetoprotein ISO RGD PMID:16822301 RGD:2292045 NCBI chr 4:50,739,197...50,758,459
Ensembl chr 4:56,571,519...56,590,391
JBrowse link
G AHR aryl hydrocarbon receptor involved_in ISO (MGI:1889403|PMID:10973493), (MGI:3794480|PMID:16443691), (MGI:72762|PMID:7732381), (MGI:81320|PMID:8692887) DFLAT PMID:7732381 PMID:8692887 PMID:10973493 PMID:16443691 MGI:1889403 MGI:3794480 MGI:72762 MGI:81320 NCBI chr 7:17,949,254...17,998,737 JBrowse link
G AK2 adenylate kinase 2 ISO RGD PMID:5123889 RGD:5490208 NCBI chr 1:32,295,668...32,323,681
Ensembl chr 1:33,480,947...33,508,621
JBrowse link
G AK3 adenylate kinase 3 ISO RGD PMID:5123889 RGD:5490208 NCBI chr 9:4,541,984...4,576,341
Ensembl chr 9:4,732,847...4,762,900
JBrowse link
G AK4 adenylate kinase 4 ISO RGD PMID:9813319 RGD:632174 NCBI chr 1:64,394,898...64,479,536
Ensembl chr 1:66,283,102...66,361,230
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 ISO RGD PMID:14729401 RGD:1643117 NCBI chr 9:51,737,305...51,916,648
Ensembl chr 9:71,680,890...71,814,085
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 ISO RGD PMID:14729401 RGD:1643117 NCBI chr15:36,925,443...37,038,288
Ensembl chr15:55,237,101...55,557,168
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO RGD PMID:16291827 RGD:2300311 NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471
JBrowse link
G ALDH9A1 aldehyde dehydrogenase 9 family member A1 ISO RGD PMID:19150623 RGD:2313411 NCBI chr 1:141,094,261...141,130,613
Ensembl chr 1:144,883,839...144,919,670
JBrowse link
G ALDOB aldolase, fructose-bisphosphate B ISO RGD PMID:8641049 RGD:2313428 NCBI chr 9:72,630,064...72,650,918
Ensembl chr 9:100,624,151...100,638,597
JBrowse link
G ANG angiogenin ISO RGD PMID:2440105 RGD:2325721 NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393
JBrowse link
G ARF6 ADP ribosylation factor 6 acts_upstream_of_or_within ISO (MGI:3653957|PMID:16880525) MGI PMID:16880525 MGI:3653957 NCBI chr14:30,482,191...30,486,741
Ensembl chr14:48,789,329...48,789,856
JBrowse link
G ARG1 arginase 1 ISO RGD PMID:8690412 RGD:4144072 NCBI chr 6:129,372,747...129,383,880
Ensembl chr 6:133,479,966...133,491,162
JBrowse link
G ASL argininosuccinate lyase ISO DNA:increased methylation:5' utr RGD PMID:9535537 PMID:10473900 RGD:1599266 RGD:1599268 NCBI chr 7:59,971,529...59,988,722
Ensembl chr 7:73,142,842...73,157,472
JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) ISO RGD PMID:237754 RGD:2316008 NCBI chr 7:89,811,363...89,831,733
Ensembl chr 7:103,392,540...103,413,046
JBrowse link
G ASS1 argininosuccinate synthase 1 ISO RGD PMID:9395312 PMID:10473900 RGD:1599266 RGD:4139912 NCBI chr 9:101,569,442...101,625,899
Ensembl chr 9:130,219,993...130,276,036
JBrowse link
G ATF2 activating transcription factor 2 involved_in ISO (MGI:3719954|PMID:17699753) MGI PMID:17699753 MGI:3719954 NCBI chr2B:62,348,245...62,444,428
Ensembl chr2B:179,799,365...179,895,007
JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (MGI:3587473|PMID:15866887) MGI PMID:15866887 MGI:3587473 NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta ISO RGD PMID:8420961 RGD:13792579 NCBI chr12:32,264,570...32,272,419
Ensembl chr12:32,519,749...32,527,753
JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:25349135 RGD:11341669 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756
JBrowse link
G BAAT bile acid-CoA:amino acid N-acyltransferase ISO RGD PMID:7575455 RGD:69770 NCBI chr 9:72,568,002...72,593,179
Ensembl chr 9:100,563,040...100,586,189
JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 ISO RGD PMID:2806552 RGD:4105456 NCBI chr 3:194,917,904...194,979,451
Ensembl chr 3:204,797,757...204,863,889
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:14160653 RGD:2303538 NCBI chr2A:27,218,699...27,245,156
Ensembl chr2A:27,306,527...27,332,804
JBrowse link
G CADM1 cell adhesion molecule 1 ISO RGD PMID:17326163 RGD:2289097 NCBI chr11:110,008,314...110,347,876
Ensembl chr11:113,950,291...114,280,324
JBrowse link
G CAST calpastatin ISO RGD PMID:16871587 RGD:5683869 NCBI chr 5:91,972,572...92,084,657
Ensembl chr 5:97,527,071...97,636,650
JBrowse link
G CCND1 cyclin D1 ISO RGD PMID:15809057 RGD:1582338 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CCND2 cyclin D2 ISO RGD PMID:15809057 RGD:1582338 NCBI chr12:4,385,957...4,417,602
Ensembl chr12:4,309,272...4,335,551
JBrowse link
G CCNE1 cyclin E1 ISO RGD PMID:15809057 RGD:1582338 NCBI chr19:26,739,285...26,751,630
Ensembl chr19:35,496,700...35,510,295
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (MGI:6284072|PMID:30635284) UniProt PMID:30635284 MGI:6284072 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO RGD PMID:11042273 RGD:7248763 NCBI chr 9:21,838,902...21,845,355
Ensembl chr 9:22,455,662...22,462,156
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha acts_upstream_of_or_within
involved_in
ISO (MGI:3688957|PMID:17021047)
(MGI:83240|PMID:8798745)
RGD
MGI
UniProt
PMID:8798745 PMID:16172914 PMID:17021047 MGI:3688957 MGI:83240 RGD:1625368 NCBI chr19:30,223,567...30,226,204 JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO RGD PMID:1377818 RGD:69946 NCBI chr20:46,533,163...46,535,282 JBrowse link
G CEBPG CCAAT enhancer binding protein gamma involved_in ISO PMID:1377818 UniProt PMID:1377818 RGD:69946 NCBI chr19:30,295,603...30,304,984
Ensembl chr19:39,046,219...39,046,671
JBrowse link
G CFC1B cripto, FRL-1, cryptic family 1B acts_upstream_of_or_within ISO (MGI:1346729|PMID:10521397) MGI PMID:10521397 MGI:1346729 NCBI chr2B:29,354,004...29,362,161 JBrowse link
G CIT citron rho-interacting serine/threonine kinase ISO RGD PMID:12411428 RGD:628497 NCBI chr12:117,264,627...117,456,069
Ensembl chr12:120,641,747...120,832,511
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 acts_upstream_of_or_within
involved_in
ISO (MGI:3847632|PMID:17644732)
(MGI:3813432|PMID:17932483)
MGI
BHF-UCL
PMID:17644732 PMID:17932483 MGI:3813432 MGI:3847632 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G COBL cordon-bleu WH2 repeat protein acts_upstream_of_or_within ISO (PMID:7586755) BHF-UCL PMID:7586755 NCBI chr 7:51,652,318...51,952,256
Ensembl chr 7:51,895,807...52,097,841
JBrowse link
G CP ceruloplasmin ISO RGD PMID:2332446 RGD:728241 NCBI chr 3:146,180,527...146,239,833
Ensembl chr 3:153,764,830...153,817,544
JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO RGD PMID:8690412 RGD:4144072 NCBI chr2B:97,735,486...97,936,623
Ensembl chr2B:216,136,857...216,337,728
JBrowse link
G CTNNB1 catenin beta 1 ISO RGD PMID:17236583 RGD:1599633 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:12162855 RGD:727721 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636
JBrowse link
G DBP D-box binding PAR bZIP transcription factor ISO RGD PMID:2331750 RGD:727680 NCBI chr19:45,631,939...45,638,962 JBrowse link
G DDX39B DExD-box helicase 39B ISO RGD PMID:1618789 RGD:632224 NCBI chr 6:31,191,333...31,203,246
Ensembl chr 6:32,081,210...32,092,569
JBrowse link
G DUT deoxyuridine triphosphatase ISO RGD PMID:11121581 RGD:5133681 NCBI chr15:27,280,025...27,292,003
Ensembl chr15:45,603,807...45,616,022
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:12454858 RGD:2289959 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G ELK1 ETS transcription factor ELK1 acts_upstream_of_or_within ISO (MGI:6472092|PMID:31877385) MGI PMID:31877385 MGI:6472092 NCBI chr  X:40,071,433...40,086,518
Ensembl chr  X:47,967,492...47,982,579
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:10231554 RGD:13204733 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
JBrowse link
G EPHX1 epoxide hydrolase 1 ISO RGD PMID:2469391 RGD:4889418 NCBI chr 1:201,271,366...201,306,635
Ensembl chr 1:206,272,866...206,307,581
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:12454858 RGD:2289959 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862
JBrowse link
G FOXM1 forkhead box M1 acts_upstream_of_or_within ISO (MGI:3522012|PMID:15531365) MGI PMID:15531365 MGI:3522012 NCBI chr12:2,978,400...2,999,077
Ensembl chr12:2,910,028...2,930,503
JBrowse link
G FPGS folylpolyglutamate synthase ISO RGD PMID:1435744 RGD:2315102 NCBI chr 9:98,921,986...98,933,542
Ensembl chr 9:127,593,592...127,604,200
JBrowse link
G FSCN1 fascin actin-bundling protein 1 ISO RGD PMID:18855019 RGD:2317768 NCBI chr 7:5,848,902...5,862,756 JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (MGI:3575862|PMID:15767668) MGI PMID:15767668 MGI:3575862 NCBI chr18:15,411,764...15,444,402 JBrowse link
G GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 ISO RGD PMID:3996734 RGD:2302171 NCBI chr14:33,371,603...33,388,098
Ensembl chr14:51,655,182...51,671,619
JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:3525024|PMID:15578515) MGI PMID:15578515 MGI:3525024 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257
JBrowse link
G HGF hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:3653957|PMID:16880525) MGI PMID:16880525 MGI:3653957 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:1855906|PMID:10804184), (MGI:3703395|PMID:16364283)
(MGI:3487182|PMID:15459110)
(MGI:1891782|PMID:11027604)
MGI PMID:10804184 PMID:11027604 PMID:15459110 PMID:16364283 MGI:1855906 MGI:1891782 MGI:3487182 MGI:3703395 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992
JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within ISO (MGI:79044|PMID:8557196) MGI PMID:8557196 MGI:79044 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222
JBrowse link
G HMBS hydroxymethylbilane synthase ISO RGD PMID:971328 RGD:25394583 NCBI chr11:113,923,004...113,931,732
Ensembl chr11:117,852,295...117,860,757
JBrowse link
G HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase ISO RGD PMID:13990 RGD:2326149 NCBI chr 1:22,993,489...23,017,307
Ensembl chr 1:23,977,723...24,001,150
JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO RGD PMID:5166591 RGD:2326169 NCBI chr 5:67,067,001...67,091,786
Ensembl chr 5:72,116,228...72,141,050
JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO RGD PMID:8620869 RGD:2326125 NCBI chr 1:82,778,489...82,798,987
Ensembl chr 1:117,775,770...117,796,679
JBrowse link
G HNF1A HNF1 homeobox A acts_upstream_of_or_within ISO (MGI:1202489|PMID:9566924) MGI PMID:9566924 MGI:1202489 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911
JBrowse link
G HNF1B HNF1 homeobox B acts_upstream_of_or_within ISO (MGI:3807614|PMID:18635606) MGI PMID:18635606 MGI:3807614 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D ISO RGD PMID:20102719 RGD:10042969 NCBI chr 4:41,825,518...41,846,166
Ensembl chr 4:47,676,599...47,696,894
JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:16488668 RGD:10002779 NCBI chr 9:40,898,593...40,911,159
Ensembl chr 9:83,324,238...83,336,756
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO RGD PMID:2581126 RGD:14694813 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G ICMT isoprenylcysteine carboxyl methyltransferase acts_upstream_of_or_within ISO (MGI:2182507|PMID:12105862) MGI PMID:12105862 MGI:2182507 NCBI chr 1:4,987,384...5,002,213
Ensembl chr 1:6,246,570...6,258,746
JBrowse link
G IFT88 intraflagellar transport 88 acts_upstream_of_or_within ISO (MGI:2155922|PMID:11773599), (MGI:892192|PMID:9176412) MGI PMID:9176412 PMID:11773599 MGI:2155922 MGI:892192 NCBI chr13:1,893,102...2,017,771
Ensembl chr13:20,206,471...20,331,204
JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO RGD PMID:12127995 RGD:2311626 NCBI chr 6:157,852,565...157,990,049
Ensembl chr 6:162,878,661...162,997,762
JBrowse link
G INSR insulin receptor ISO RGD PMID:6364984 RGD:14701029 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 acts_upstream_of_or_within ISO (MGI:1096257|PMID:9376320) MGI PMID:9376320 MGI:1096257 NCBI chr 6:15,100,415...15,376,505
Ensembl chr 6:15,466,050...15,739,170
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (MGI:1338596|PMID:10352021) MGI PMID:10352021 MGI:1338596 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G KLF1 Kruppel like factor 1 acts_upstream_of_or_within ISO (MGI:73364|PMID:7753194) MGI PMID:7753194 MGI:73364 NCBI chr19:12,446,130...12,449,238
Ensembl chr19:13,188,652...13,191,425
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:1526114 RGD:11060153 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335
JBrowse link
G LBP lipopolysaccharide binding protein ISO RGD PMID:20978830 RGD:9685195 NCBI chr20:34,670,128...34,703,046
Ensembl chr20:35,780,768...35,813,188
JBrowse link
G LIPC lipase C, hepatic type ISO RGD PMID:11004003 RGD:2307448 NCBI chr15:37,363,507...37,537,723
Ensembl chr15:55,814,017...55,847,005
JBrowse link
G LOC100972297 polycystin-1 acts_upstream_of_or_within ISO (MGI:5441703|PMID:21685914) MGI PMID:21685914 MGI:5441703 NCBI chr16:604,927...1,697,831 JBrowse link
G LOC100981854 cyclic AMP-dependent transcription factor ATF-7 involved_in ISO (MGI:3719954|PMID:17699753) MGI PMID:17699753 MGI:3719954 NCBI chr12:35,128,031...35,245,505
Ensembl chr12:35,914,378...36,021,141
JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B ISO RGD PMID:17565389 RGD:2291935 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463
JBrowse link
G LSR lipolysis stimulated lipoprotein receptor involved_in ISO (MGI:3052428|PMID:15265030) HGNC-UCL PMID:15265030 MGI:3052428 NCBI chr19:32,195,036...32,214,300
Ensembl chr19:40,932,180...40,951,448
JBrowse link
G MAN2A1 mannosidase alpha class 2A member 1 acts_upstream_of_or_within ISO (MGI:3652665|PMID:16754854) MGI PMID:16754854 MGI:3652665 NCBI chr 5:105,034,104...105,219,011
Ensembl chr 5:110,841,349...111,025,187
JBrowse link
G MED1 mediator complex subunit 1 acts_upstream_of_or_within ISO (MGI:2682174|PMID:14500757) MGI PMID:14500757 MGI:2682174 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:76093|PMID:7651534) RGD
MGI
PMID:7651534 PMID:8506951 MGI:76093 RGD:2317549 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159
JBrowse link
G MPST mercaptopyruvate sulfurtransferase ISO RGD PMID:6573924 RGD:9685558 NCBI chr22:17,933,995...17,944,196
Ensembl chr22:35,770,209...35,780,250
JBrowse link
G MRTFB myocardin related transcription factor B acts_upstream_of_or_within ISO (MGI:3695837|PMID:17183527) MGI PMID:17183527 MGI:3695837 NCBI chr16:12,999,165...13,195,012
Ensembl chr16:14,493,351...14,613,860
JBrowse link
G NAT1 N-acetyltransferase 1 ISO RGD PMID:18799802 RGD:2303764 NCBI chr 8:17,425,852...17,439,684
Ensembl chr 8:14,386,481...14,392,462
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:66069|PMID:7926784) MGI PMID:7926784 MGI:66069 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295
JBrowse link
G NODAL nodal growth differentiation factor acts_upstream_of_or_within ISO (MGI:2155575|PMID:11311163) MGI PMID:11311163 MGI:2155575 NCBI chr10:66,906,866...66,916,938
Ensembl chr10:69,433,959...69,443,972
JBrowse link
G NOTCH1 notch receptor 1 acts_upstream_of_or_within ISO (MGI:3045664|PMID:15226394) MGI PMID:15226394 MGI:3045664 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740
JBrowse link
G NOTCH2 notch receptor 2 acts_upstream_of_or_within ISO (MGI:5616947|PMID:25446530) MGI PMID:25446530 MGI:5616947 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840
JBrowse link
G NTS neurotensin ISO RGD PMID:8342998 RGD:9743870 NCBI chr12:83,402,313...83,410,356
Ensembl chr12:86,640,720...86,648,745
JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within ISO (MGI:3763866|PMID:17936262) MGI PMID:17936262 MGI:3763866 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062
JBrowse link
G ONECUT2 one cut homeobox 2 acts_upstream_of_or_within ISO (MGI:3763866|PMID:17936262) MGI PMID:17936262 MGI:3763866 NCBI chr18:50,826,110...50,882,127 JBrowse link
G OTC ornithine transcarbamylase ISO RGD PMID:8690412 RGD:4144072 NCBI chr  X:30,796,828...30,868,144
Ensembl chr  X:38,505,232...38,575,819
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in
acts_upstream_of_or_within
ISO PMID:12552133
(PMID:12552133)
HGNC-UCL PMID:12552133 RGD:629554 NCBI chr 1:54,323,036...54,355,397
Ensembl chr 1:55,911,016...55,936,456
JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO (MGI:4355651|PMID:19619492) MGI PMID:19619492 MGI:4355651 NCBI chr13:9,199,572...9,206,202 JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha acts_upstream_of_or_within ISO (MGI:5582991|PMID:24691033) MGI PMID:24691033 MGI:5582991 NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in
acts_upstream_of_or_within
ISO (PMID:11891195)
(MGI:5441703|PMID:21685914)
UniProt
MGI
PMID:11891195 PMID:21685914 MGI:5441703 NCBI chr 4:80,295,243...80,365,271
Ensembl chr 4:91,019,734...91,086,775
JBrowse link
G PKM pyruvate kinase M1/2 ISO RGD PMID:7327170 RGD:2303137 NCBI chr15:51,149,584...51,182,193
Ensembl chr15:69,913,455...69,945,832
JBrowse link
G PRKCSH protein kinase C substrate 80K-H acts_upstream_of_or_within ISO (MGI:5441703|PMID:21685914) MGI PMID:21685914 MGI:5441703 NCBI chr19:10,981,398...10,997,062
Ensembl chr19:11,693,620...11,707,728
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa acts_upstream_of_or_within ISO (MGI:1306904|PMID:9788960) RGD
MGI
PMID:7660357 PMID:9788960 MGI:1306904 RGD:1299299 NCBI chr2B:32,846,899...32,859,060
Ensembl chr2B:128,083,794...128,094,625
JBrowse link
G PROS1 protein S ISO RGD PMID:7660357 RGD:1299299 NCBI chr 3:90,934,641...91,039,059
Ensembl chr 3:97,615,734...97,718,756
JBrowse link
G PROX1 prospero homeobox 1 involved_in ISO (PMID:11789987) RGD
BHF-UCL
PMID:11789987 PMID:16770575 RGD:5133274 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 ISO RGD PMID:24707720 RGD:9854625 NCBI chr 6:32,423,614...32,429,062
Ensembl chr 6:33,539,060...33,564,402
JBrowse link
G PTCD2 pentatricopeptide repeat domain 2 acts_upstream_of_or_within ISO (MGI:3829520|PMID:18729827) MGI PMID:18729827 MGI:3829520 NCBI chr 5:42,953,639...42,992,301
Ensembl chr 5:43,552,528...43,591,162
JBrowse link
G PTN pleiotrophin ISO RGD PMID:12057922 RGD:727382 NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
JBrowse link
G QDPR quinoid dihydropteridine reductase ISO RGD PMID:710385 RGD:5128606 NCBI chr 4:11,906,439...11,932,311
Ensembl chr 4:17,199,772...17,225,667
JBrowse link
G RARA retinoic acid receptor alpha ISO RGD PMID:15388488 RGD:2314298 NCBI chr17:16,932,485...16,980,958 JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 acts_upstream_of_or_within ISO (MGI:3689241|PMID:17015619) MGI PMID:17015619 MGI:3689241 NCBI chr 8:49,046,830...49,138,795
Ensembl chr 8:46,430,131...46,521,722
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in ISO (MGI:76008|PMID:7603567) UniProt PMID:7603567 MGI:76008 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G RGN regucalcin ISO RGD PMID:8794449 PMID:9546611 RGD:9590173 RGD:9590212 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
G RHBDD3 rhomboid domain containing 3 acts_upstream_of_or_within ISO (MGI:5492204|PMID:23610400) MGI PMID:23610400 MGI:5492204 NCBI chr22:10,315,438...10,323,803
Ensembl chr22:28,123,115...28,131,090
JBrowse link
G RPGRIP1L RPGRIP1 like acts_upstream_of_or_within ISO (MGI:3716248|PMID:17558409) MGI PMID:17558409 MGI:3716248 NCBI chr16:33,836,361...33,939,265
Ensembl chr16:52,920,796...53,023,174
JBrowse link
G RXRA retinoid X receptor alpha ISO RGD PMID:14729401 RGD:1643117 NCBI chr 9:105,424,046...105,539,241
Ensembl chr 9:134,082,865...134,144,704
JBrowse link
G SEC63 SEC63 homolog, protein translocation regulator acts_upstream_of_or_within ISO (MGI:5441703|PMID:21685914) MGI PMID:21685914 MGI:5441703 NCBI chr 6:105,673,265...105,757,422
Ensembl chr 6:109,538,184...109,595,518
JBrowse link
G SLC25A4 solute carrier family 25 member 4 ISO RGD PMID:9468308 RGD:9681468 NCBI chr 4:177,310,982...177,315,016
Ensembl chr 4:189,531,914...189,534,549
JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 ISO RGD PMID:15288467 RGD:2303131 NCBI chr12:65,386,042...65,492,240 JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 ISO RGD PMID:15345472 RGD:2316987 NCBI chr11:70,211,124...70,266,513
Ensembl chr11:73,515,433...73,570,410
JBrowse link
G SMAD3 SMAD family member 3 acts_upstream_of_or_within ISO (MGI:3618021|PMID:15183723) MGI PMID:15183723 MGI:3618021 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (MGI:3610843|PMID:16287714) MGI PMID:16287714 MGI:3610843 NCBI chr19:10,515,216...10,616,155
Ensembl chr19:11,250,006...11,334,952
JBrowse link
G SOD2 superoxide dismutase 2 acts_upstream_of_or_within ISO (MGI:3718142|PMID:17367743) MGI PMID:17367743 MGI:3718142 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
G SP1 Sp1 transcription factor acts_upstream_of_or_within ISO (MGI:3717030|PMID:17584888) MGI PMID:17584888 MGI:3717030 NCBI chr12:35,338,492...35,374,462
Ensembl chr12:36,127,681...36,158,356
JBrowse link
G SP3 Sp3 transcription factor acts_upstream_of_or_within ISO (MGI:3717030|PMID:17584888) MGI PMID:17584888 MGI:3717030 NCBI chr2B:61,185,975...61,243,155
Ensembl chr2B:178,639,677...178,692,848
JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO RGD PMID:8770891 RGD:4892048 NCBI chr 5:6,953,795...6,996,010
Ensembl chr 5:6,629,093...6,664,264
JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 ISO RGD PMID:9199345 RGD:11039429 NCBI chr14:50,320,820...50,365,650
Ensembl chr14:69,230,730...69,236,596
JBrowse link
G TAF10 TATA-box binding protein associated factor 10 acts_upstream_of_or_within ISO (MGI:3806427|PMID:18722179) MGI PMID:18722179 MGI:3806427 NCBI chr11:6,742,862...6,744,260 JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in ISO (MGI:2663364|PMID:12773577) BHF-UCL PMID:12773577 MGI:2663364 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G THRA thyroid hormone receptor alpha ISO RGD PMID:17496154 RGD:2314319 NCBI chr17:17,196,459...17,226,263 JBrowse link
G TK1 thymidine kinase 1 ISO RGD PMID:995499 RGD:2317236 NCBI chr17:72,251,416...72,265,308
Ensembl chr17:77,803,749...77,816,747
JBrowse link
G UPB1 beta-ureidopropionase 1 ISO RGD PMID:6870258 RGD:2317093 NCBI chr22:5,300,686...5,332,735
Ensembl chr22:22,166,370...22,197,360
JBrowse link
G UPF2 UPF2 regulator of nonsense mediated mRNA decay acts_upstream_of_or_within ISO (MGI:4821037|PMID:20657840) MGI PMID:20657840 MGI:4821037 NCBI chr10:11,924,483...12,047,617
Ensembl chr10:11,916,893...12,020,760
JBrowse link
G UROD uroporphyrinogen decarboxylase ISO RGD PMID:6219675 RGD:4145103 NCBI chr 1:44,315,912...44,319,356
Ensembl chr 1:45,679,744...45,683,185
JBrowse link
G VWF von Willebrand factor acts_upstream_of_or_within ISO (MGI:70957|PMID:7854452) MGI PMID:7854452 MGI:70957 NCBI chr12:6,073,836...6,249,806
Ensembl chr12:5,990,612...6,165,153
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:15312687) UniProt PMID:15312687 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:1352298|PMID:10652269) UniProt PMID:10652269 MGI:1352298 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (MGI:5609934|PMID:23117660) MGI PMID:23117660 MGI:5609934 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link
determination of liver left/right asymmetry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC39 coiled-coil domain containing 39 involved_in ISO (PMID:22693285) BHF-UCL PMID:22693285 NCBI chr 3:177,640,127...177,705,885
Ensembl chr 3:185,813,245...185,878,362
JBrowse link
G CCDC40 coiled-coil domain containing 40 involved_in ISO (PMID:22693285) BHF-UCL PMID:22693285 NCBI chr17:74,120,483...74,187,323
Ensembl chr17:79,656,287...79,722,565
JBrowse link
G DNAAF1 dynein axonemal assembly factor 1 involved_in ISO (PMID:19944405) BHF-UCL PMID:19944405 NCBI chr16:64,810,498...64,843,705
Ensembl chr16:84,154,130...84,184,914
JBrowse link
G NPHP3 nephrocystin 3 involved_in ISO (PMID:20007846) BHF-UCL PMID:20007846 NCBI chr 3:129,753,399...129,795,300 JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:21719175) BHF-UCL PMID:21719175 NCBI chr 4:80,295,243...80,365,271
Ensembl chr 4:91,019,734...91,086,775
JBrowse link
G ZIC3 Zic family member 3 involved_in ISO (PMID:9354794) BHF-UCL PMID:9354794 NCBI chr  X:126,691,534...126,705,788
Ensembl chr  X:136,954,024...136,967,819
JBrowse link
hepatoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GGT1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chr22:5,424,334...5,469,705 JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:3720549|PMID:17580084) MGI PMID:17580084 MGI:3720549 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992
JBrowse link
G HNF1B HNF1 homeobox B acts_upstream_of_or_within ISO (MGI:3807614|PMID:18635606) MGI PMID:18635606 MGI:3807614 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863
JBrowse link
hepatocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 ISO RGD PMID:11668598 RGD:2306909 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO RGD PMID:12939595 RGD:4144098 NCBI chr2B:97,735,486...97,936,623
Ensembl chr2B:216,136,857...216,337,728
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:17574236 RGD:2306655 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636
JBrowse link
G E2F7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chr12:74,540,049...74,582,561
Ensembl chr12:77,388,950...77,433,262
JBrowse link
G E2F8 E2F transcription factor 8 involved_in ISO (MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264) UniProt PMID:23064264 PMID:23064266 MGI:5449497 MGI:5449498 NCBI chr11:19,250,045...19,267,629
Ensembl chr11:19,162,837...19,179,744
JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chr22:5,424,334...5,469,705 JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:1891782|PMID:11027604) MGI PMID:11027604 MGI:1891782 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992
JBrowse link
G HNF1B HNF1 homeobox B ISO RGD PMID:18286537 RGD:2312718 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:19621519 RGD:12904750 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536
JBrowse link
G ITGA2 integrin subunit alpha 2 ISO RGD PMID:16458388 RGD:2307397 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720
JBrowse link
G KRT18 keratin 18 ISO RGD PMID:24340101 PMID:28941653 RGD:27226712 RGD:27226713 NCBI chr12:35,807,660...35,811,691
Ensembl chr12:36,587,149...36,591,196
JBrowse link
G PROX1 prospero homeobox 1 involved_in
acts_upstream_of_or_within
ISO (PMID:15232737) BHF-UCL PMID:15232737 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763
JBrowse link
G TAF10 TATA-box binding protein associated factor 10 acts_upstream_of_or_within ISO (MGI:3806427|PMID:18722179) MGI PMID:18722179 MGI:3806427 NCBI chr11:6,742,862...6,744,260 JBrowse link
G WNT1 Wnt family member 1 ISO RGD PMID:20413689 RGD:2326223 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583
JBrowse link
hepatocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPB CCAAT enhancer binding protein beta involved_in ISO PMID:10635333
(MGI:3778721|PMID:10635333)
UniProt PMID:10635333 MGI:3778721 RGD:10047310 NCBI chr20:46,533,163...46,535,282 JBrowse link
G FGL1 fibrinogen like 1 involved_in ISO (PMID:19880967) UniProt PMID:19880967 NCBI chr 8:17,083,524...17,128,152
Ensembl chr 8:14,035,855...14,066,956
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:84432|PMID:8910279) UniProt PMID:8910279 MGI:84432 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G MKI67 marker of proliferation Ki-67 acts_upstream_of_or_within ISO (MGI:5616947|PMID:25446530) MGI PMID:25446530 MGI:5616947 NCBI chr10:124,684,336...124,714,143
Ensembl chr10:128,936,037...128,962,555
JBrowse link
G NOTCH2 notch receptor 2 acts_upstream_of_or_within ISO (MGI:5616947|PMID:25446530) MGI PMID:25446530 MGI:5616947 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29138817 RGD:15042871 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058
JBrowse link
G PROX1 prospero homeobox 1 acts_upstream_of_or_within ISO (MGI:1860507|PMID:10888866) MGI PMID:10888866 MGI:1860507 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763
JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 involved_in ISO (MGI:3778721|PMID:10635333) UniProt PMID:10635333 MGI:3778721 NCBI chr 1:25,792,428...25,837,950
Ensembl chr 1:26,856,057...26,900,532
JBrowse link
G TGFA transforming growth factor alpha involved_in ISO PMID:10635333
(MGI:3778721|PMID:10635333)
UniProt PMID:10635333 MGI:3778721 RGD:10047310 NCBI chr2A:70,510,727...70,617,628
Ensembl chr2A:71,625,196...71,731,461
JBrowse link
intrahepatic bile duct development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAK cyclin G associated kinase acts_upstream_of_or_within ISO (MGI:5305417|PMID:18434600) MGI PMID:18434600 MGI:5305417 NCBI chr 4:952,474...1,049,612
Ensembl chr 4:883,096...967,473
JBrowse link
G NOTCH2 notch receptor 2 acts_upstream_of_or_within ISO (MGI:5616947|PMID:25446530) MGI PMID:25446530 MGI:5616947 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840
JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3852603|PMID:19403103) MGI PMID:19403103 MGI:3852603 NCBI chr17:66,028,737...66,034,122 JBrowse link
liver morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUL3 cullin 3 acts_upstream_of_or_within ISO (MGI:3713609|PMID:17339333) MGI PMID:17339333 MGI:3713609 NCBI chr2B:111,714,533...111,827,080
Ensembl chr2B:230,289,195...230,378,991
JBrowse link
G NOTCH2 notch receptor 2 acts_upstream_of_or_within ISO (MGI:5616947|PMID:25446530) MGI PMID:25446530 MGI:5616947 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 acts_upstream_of_or_within ISO (MGI:5298314|PMID:21803851) MGI PMID:21803851 MGI:5298314 NCBI chr 4:97,612,439...97,745,544
Ensembl chr 4:108,269,082...108,358,400
JBrowse link
liver regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:8855951 RGD:8548508 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G AFP alpha fetoprotein ISO RGD PMID:2460696 RGD:126848734 NCBI chr 4:50,739,197...50,758,459
Ensembl chr 4:56,571,519...56,590,391
JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 ISO RGD PMID:6895999 RGD:11035238 NCBI chr  X:47,219,588...47,241,592
Ensembl chr  X:55,451,794...55,473,680
JBrowse link
G ANGPT1 angiopoietin 1 ISO RGD PMID:11549276 RGD:704403 NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO RGD PMID:11032760 RGD:13782137 NCBI chr17:3,992,088...4,013,998
Ensembl chr17:3,965,925...3,998,382
JBrowse link
G AURKA aurora kinase A acts_upstream_of_or_within ISO (PMID:19435814) MGI PMID:19435814 NCBI chr20:52,707,757...52,730,579
Ensembl chr20:53,994,881...54,017,339
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO RGD PMID:21503946 RGD:11531107 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G CCND1 cyclin D1 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CEBPB CCAAT enhancer binding protein beta involved_in ISO (MGI:1277818|PMID:9727068) UniProt PMID:9727068 MGI:1277818 NCBI chr20:46,533,163...46,535,282 JBrowse link
G CFTR CF transmembrane conductance regulator ISO RGD PMID:1378998 RGD:11567227 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864
JBrowse link
G CLDN1 claudin 1 ISO RGD PMID:15826721 RGD:11344894 NCBI chr 3:187,328,629...187,345,360
Ensembl chr 3:195,882,239...195,899,248
JBrowse link
G CPB2 carboxypeptidase B2 ISO RGD PMID:19386599 RGD:7243112 NCBI chr13:26,926,788...26,979,767 JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO RGD PMID:31953200 RGD:25823179 NCBI chr11:63,841,028...63,928,242
Ensembl chr11:67,144,736...67,205,481
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO RGD PMID:8573159 RGD:11565141 NCBI chr20:689,494...752,092
Ensembl chr20:456,629...521,126
JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 ISO RGD PMID:8573159 RGD:11565141 NCBI chr16:38,426,399...38,466,575
Ensembl chr16:57,557,270...57,596,218
JBrowse link
G CSNK2B casein kinase 2 beta ISO RGD PMID:8573159 RGD:11565141 NCBI chr 6:31,327,250...31,331,250 JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:2401457 PMID:20395437 RGD:10395295 RGD:38599218 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (MGI:5637451|PMID:25477280) MGI PMID:25477280 MGI:5637451 NCBI chr17:14,572,868...14,618,012
Ensembl chr17:14,814,054...14,842,295
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (MGI:5637451|PMID:25477280) MGI PMID:25477280 MGI:5637451 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726
JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:10632538 RGD:8662889 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FGA fibrinogen alpha chain ISO RGD PMID:3817019 RGD:728788 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:16162160 RGD:10402121 NCBI chr13:9,584,850...9,779,542 JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO RGD PMID:24880092 RGD:9685725 NCBI chr16:716,640...720,196
Ensembl chr16:2,073,064...2,076,592
JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chr22:5,424,334...5,469,705 JBrowse link
G GLI1 GLI family zinc finger 1 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) RGD
MGI
PMID:22024090 PMID:22790641 PMID:23740243 MGI:5515698 RGD:12832760 RGD:12911223 NCBI chr12:31,453,759...31,466,194
Ensembl chr12:31,710,057...31,722,473
JBrowse link
G GLI3 GLI family zinc finger 3 ISO RGD PMID:22024090 RGD:12911223 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865
JBrowse link
G HAMP hepcidin antimicrobial peptide ISO RGD PMID:22364558 RGD:8694419 NCBI chr19:32,228,701...32,231,494
Ensembl chr19:40,964,445...40,968,861
JBrowse link
G HFE homeostatic iron regulator ISO RGD PMID:22364558 RGD:8694419 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591
JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:24815159 RGD:10755743 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 ISO RGD PMID:16081591 RGD:1599972 NCBI chr16:23,979,487...23,984,225
Ensembl chr16:31,352,322...31,356,803
JBrowse link
G IHH Indian hedgehog signaling molecule ISO RGD PMID:22024090 RGD:12911223 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506
JBrowse link
G IL10 interleukin 10 ISO RGD PMID:11813605 RGD:11049526 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:24412291 RGD:14696652 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:84432|PMID:8910279) UniProt PMID:8910279 MGI:84432 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G INSR insulin receptor ISO RGD PMID:23633480 RGD:9685423 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:24814243 RGD:13793384 NCBI chr 3:4,448,574...4,802,545
Ensembl chr 3:4,572,921...4,904,811
JBrowse link
G KLKB1 kallikrein B1 ISO RGD PMID:9869390 RGD:7297052 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:3335218 RGD:10059623 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NCL nucleolin ISO RGD PMID:7490256 RGD:9686389 NCBI chr2B:118,703,148...118,712,893
Ensembl chr2B:237,490,378...237,500,193
JBrowse link
G NFKBIA NFKB inhibitor alpha ISO RGD PMID:24512945 RGD:10413865 NCBI chr14:16,155,331...16,158,588 JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:14635188 RGD:11534994 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29138817 RGD:15042871 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058
JBrowse link
G PCNA proliferating cell nuclear antigen ISO RGD PMID:7906221 RGD:10448980 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 ISO RGD PMID:191106 RGD:11554175 NCBI chr2A:55,792,412...55,848,242
Ensembl chr2A:56,931,365...56,986,326
JBrowse link
G POU2F1 POU class 2 homeobox 1 ISO RGD PMID:1841628 RGD:9743904 NCBI chr 1:142,653,296...142,860,572
Ensembl chr 1:146,439,581...146,633,921
JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO RGD PMID:15837430 RGD:2299961 NCBI chr19:46,691,795...46,705,179
Ensembl chr19:55,610,938...55,623,135
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:15837430 RGD:2299961 NCBI chr14:3,737,741...3,746,646
Ensembl chr14:21,836,984...21,846,018
JBrowse link
G PTCH1 patched 1 ISO RGD PMID:22024090 RGD:12911223 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453
JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 ISO RGD PMID:7591957 RGD:1599982 NCBI chr 9:80,528,896...80,651,629
Ensembl chr 9:108,699,761...108,787,464
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:9015365 RGD:10003155 NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:22227930 RGD:9850085 NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252
JBrowse link
G RGN regucalcin ISO RGD PMID:7759556 RGD:9590197 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
G RPL10 ribosomal protein L10 ISO RGD PMID:6121318 RGD:11038709 NCBI chr  X:143,839,739...143,844,026 JBrowse link
G RPL13 ribosomal protein L13 ISO RGD PMID:6121318 RGD:11038709 NCBI chr16:70,312,241...70,314,956 JBrowse link
G RPL18 ribosomal protein L18 ISO RGD PMID:6121318 RGD:11038709 NCBI chr19:45,617,033...45,620,954
Ensembl chr19:54,209,173...54,213,293
JBrowse link
G RPL19 ribosomal protein L19 ISO RGD PMID:6121318 RGD:11038709 NCBI chr17:18,066,656...18,071,158
Ensembl chr17:18,342,003...18,346,399
JBrowse link
G RPL30 ribosomal protein L30 ISO RGD PMID:6121318 RGD:11038709 NCBI chr 8:94,678,823...94,682,726
Ensembl chr 8:96,863,944...96,867,526
JBrowse link
G RPL32 ribosomal protein L32 ISO RGD PMID:6121318 RGD:11038709 NCBI chr 3:12,759,205...12,764,800
Ensembl chr 3:13,103,471...13,109,044
JBrowse link
G RPL7 ribosomal protein L7 ISO RGD PMID:6121318 RGD:11038709 NCBI chr 8:69,829,356...69,833,184
Ensembl chr 8:71,476,492...71,480,279
JBrowse link
G RPS15 ribosomal protein S15 ISO RGD PMID:2829897 RGD:11040696
G RPS16 ribosomal protein S16 ISO RGD PMID:6121318 RGD:11038709 NCBI chr19:36,531,284...36,534,156
Ensembl chr19:45,079,106...45,085,351
JBrowse link
G RPS24 ribosomal protein S24 ISO RGD PMID:7612009 RGD:11041663 NCBI chr10:74,554,301...74,561,240
Ensembl chr10:77,217,228...77,238,519
JBrowse link
G SERPINA10 serpin family A member 10 ISO RGD PMID:8670294 RGD:729731 NCBI chr14:74,914,680...74,927,325
Ensembl chr14:94,248,362...94,257,835
JBrowse link
G SHH sonic hedgehog signaling molecule ISO RGD PMID:22790641 RGD:12832760 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651
JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 ISO RGD PMID:23633480 RGD:9685423 NCBI chr17:52,083,676...52,087,454
Ensembl chr17:56,937,295...56,944,425
JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 ISO RGD PMID:7686911 RGD:729792 NCBI chr14:50,320,820...50,365,650
Ensembl chr14:69,230,730...69,236,596
JBrowse link
G SULF2 sulfatase 2 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr20:43,992,927...44,122,598
Ensembl chr20:45,074,069...45,173,893
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD PMID:25862490 RGD:11073669 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:9178702 RGD:14995465 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TYMS thymidylate synthetase ISO RGD PMID:2707640 RGD:2317422 NCBI chr18:13,653,085...13,668,478
Ensembl chr18:17,295,182...17,310,320
JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:19104935 RGD:7204431 NCBI chr11:69,047,397...69,056,056
Ensembl chr11:72,354,529...72,363,185
JBrowse link
G VTN vitronectin ISO RGD PMID:10988248 RGD:10003090 NCBI chr17:28,403,813...28,407,202
Ensembl chr17:28,906,508...28,909,583
JBrowse link
G VWF von Willebrand factor ISO RGD PMID:12217600 RGD:727737 NCBI chr12:6,073,836...6,249,806
Ensembl chr12:5,990,612...6,165,153
JBrowse link
G WDR35 WD repeat domain 35 ISO RGD PMID:18472094 RGD:11553927 NCBI chr2A:19,896,498...19,977,295
Ensembl chr2A:20,014,127...20,093,810
JBrowse link
negative regulation of hepatocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FRZB frizzled related protein acts_upstream_of_or_within ISO (MGI:4356222|PMID:19562671) MGI PMID:19562671 MGI:4356222 NCBI chr2B:70,106,378...70,139,333
Ensembl chr2B:187,915,579...187,948,855
JBrowse link
negative regulation of hepatocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A ISO RGD PMID:24190239 RGD:11252157 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO PMID:15467833
(MGI:3057041|PMID:15467833)
UniProt PMID:15467833 MGI:3057041 RGD:11059592 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739
JBrowse link
G CPB2 carboxypeptidase B2 ISO RGD PMID:19386599 RGD:7243112 NCBI chr13:26,926,788...26,979,767 JBrowse link
G LIMS1 LIM zinc finger domain containing 1 acts_upstream_of_or_within ISO (MGI:5559100|PMID:24058607) MGI PMID:24058607 MGI:5559100 NCBI chr2A:94,739,338...94,928,835 JBrowse link
G LIMS2 LIM zinc finger domain containing 2 acts_upstream_of_or_within ISO (MGI:5559100|PMID:24058607) MGI PMID:24058607 MGI:5559100 NCBI chr2B:32,594,330...32,637,697
Ensembl chr2B:128,304,799...128,347,951
JBrowse link
positive regulation of hepatocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISO RGD PMID:19229878 RGD:8885195 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G FOXA3 forkhead box A3 ISO RGD PMID:9878541 RGD:2315086 NCBI chr19:42,873,933...42,883,479
Ensembl chr19:51,410,473...51,418,744
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) BHF-UCL PMID:18593560 MGI:4441249 NCBI chr15:68,440,626...68,441,935
Ensembl chr15:87,645,768...87,647,210
JBrowse link
positive regulation of hepatocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:16033771 RGD:11341689 NCBI chr2B:88,373,057...88,429,959
Ensembl chr2B:206,528,943...206,577,045
JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISO PMID:16756958 UniProt PMID:16756958 RGD:10047366 NCBI chr 5:137,949,100...138,054,553
Ensembl chr 5:144,056,387...144,078,001
JBrowse link
G FGF18 fibroblast growth factor 18 involved_in ISO PMID:16756958 UniProt PMID:16756958 RGD:10047366 NCBI chr 5:166,765,061...166,802,277 JBrowse link
G HPN hepsin involved_in ISO (PMID:15614436) UniProt PMID:15614436 NCBI chr19:31,985,761...32,012,841
Ensembl chr19:40,725,319...40,750,628
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:24412291 RGD:14696652 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:24814243 RGD:13793384 NCBI chr 3:4,448,574...4,802,545
Ensembl chr 3:4,572,921...4,904,811
JBrowse link
G MDK midkine involved_in ISO (MGI:3606557|PMID:15482347) UniProt PMID:15482347 MGI:3606557 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254
JBrowse link
G MED1 mediator complex subunit 1 acts_upstream_of_or_within ISO (MGI:3719773|PMID:17438330) MGI PMID:17438330 MGI:3719773 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G PTN pleiotrophin involved_in ISO (MGI:3606557|PMID:15482347) RGD
UniProt
PMID:15482347 PMID:16226713 MGI:3606557 RGD:9834996 NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
JBrowse link
G RTN4 reticulon 4 involved_in ISO (MGI:6282933|PMID:23299899) UniProt PMID:23299899 MGI:6282933 NCBI chr2A:55,129,272...55,207,031 JBrowse link
G TNF tumor necrosis factor ISO with PCB 126 or TCDD RGD PMID:9111198 PMID:17557910 RGD:14995469 RGD:14995481 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in ISO (MGI:4943408|PMID:15962316) BHF-UCL PMID:15962316 MGI:4943408 NCBI chr 6:135,617,465...135,634,085
Ensembl chr 6:139,705,255...139,720,819
JBrowse link
G WNT3A Wnt family member 3A acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:1352298|PMID:10652269) UniProt PMID:10652269 MGI:1352298 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
regulation of hepatocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI1 GLI family zinc finger 1 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr12:31,453,759...31,466,194
Ensembl chr12:31,710,057...31,722,473
JBrowse link
G IFNG interferon gamma ISO RGD PMID:15799032 RGD:8142374 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G PLAU plasminogen activator, urokinase ISO RGD PMID:17587687 RGD:6484147 NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136
JBrowse link
G SULF2 sulfatase 2 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) MGI PMID:23740243 MGI:5515698 NCBI chr20:43,992,927...44,122,598
Ensembl chr20:45,074,069...45,173,893
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12657
    developmental process 5905
      anatomical structure development 5509
        animal organ development 3658
          gland development 597
            liver development 248
              determination of liver left/right asymmetry 6
              hepatoblast differentiation 3
              hepatocyte differentiation + 18
              intrahepatic bile duct development 3
              liver morphogenesis + 34
              liver regeneration 74
              liver trabecula formation 0
Path 2
Term Annotations click to browse term
  biological_process 12657
    developmental process 5905
      anatomical structure development 5509
        multicellular organism development 5038
          system development 4740
            animal organ development 3658
              gland development 597
                liver development 248
                  determination of liver left/right asymmetry 6
                  hepatoblast differentiation 3
                  hepatocyte differentiation + 18
                  intrahepatic bile duct development 3
                  liver morphogenesis + 34
                  liver regeneration 74
                  liver trabecula formation 0
paths to the root