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ONTOLOGY REPORT - ANNOTATIONS


Term:complement binding
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Accession:GO:0001848 term browser browse the term
Definition:Binding to a component or product of the complement cascade.
Comment:Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways.



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complement binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4b complement C4B (Chido blood group) enables ISO (PMID:2395880) RGD PMID:2395880 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G C4bpa complement component 4 binding protein, alpha TAS RGD PMID:12232502 RGD:1299828 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C8a complement C8 alpha chain IPI RGD PMID:3312411 RGD:1600696 NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754
JBrowse link
G C8g complement C8 gamma chain enables IPI
IBA
PMID:21873635 RGD
GO_Central
PMID:3312411 PMID:21873635 RGD:1600696, RGD:13792537 NCBI chr 3:8,320,495...8,323,495
Ensembl chr 3:8,305,920...8,323,495
JBrowse link
G Cd59 CD59 molecule enables IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:9038722 PMID:21873635 RGD:1600496, RGD:13792537 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Cr2 complement C3d receptor 2 enables ISO (PMID:11034390) RGD PMID:11034390 NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235
JBrowse link
G Serping1 serpin family G member 1 enables ISO UniProtKB:P04281 (MGI:1261381|PMID:9652403) RGD PMID:9652403 MGI:1261381 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
complement component C1q complex binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum enables IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:23544079)
Ensembl
RGD
PMID:23544079 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G C1qbp complement C1q binding protein enables IDA
IBA
ISO
human C1q
PMID:21873635
(PMID:8195709)
RGD PMID:8195709 PMID:9414106 PMID:21873635 RGD:69785, RGD:13792537 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C4a complement C4A enables ISO (PMID:2395880) RGD PMID:2395880 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080
JBrowse link
G C4b complement C4B (Chido blood group) enables ISO (PMID:2395880) RGD PMID:2395880 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G Cd93 CD93 molecule enables ISO (PMID:11781389) RGD PMID:11781389 NCBI chr 3:135,891,859...135,898,378
Ensembl chr 3:135,891,859...135,898,378
JBrowse link
G Crp C-reactive protein enables ISO
IBA
(PMID:23544079)
PMID:21873635
RGD PMID:23544079 PMID:21873635 RGD:13792537 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Megf10 multiple EGF-like domains 10 enables ISO (PMID:27170117) RGD PMID:27170117 NCBI chr18:50,605,231...50,755,441
Ensembl chr18:50,605,656...50,754,456
JBrowse link
G Mptx1 mucosal pentraxin 1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:85,728,076...85,731,469
Ensembl chr13:85,728,076...85,731,469
JBrowse link
G Ptx3 pentraxin 3 enables ISO
IBA
(PMID:23544079)
PMID:21873635
RGD PMID:23544079 PMID:21873635 RGD:13792537 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
complement component C3a binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 IDA RGD PMID:9464274 PMID:15292245 RGD:724614, RGD:2303020 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Phb1 prohibitin 1 enables ISO (PMID:17070910) RGD PMID:17070910 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
complement component C3b binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfh complement factor H enables ISO PR:P01027|UniProtKB:P01024 (MGI:3613281|PMID:16023208), (MGI:3692807|PMID:17028856) RGD PMID:16023208 PMID:17028856 MGI:3613281 MGI:3692807 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Cfhr4 complement factor H-related 4 enables ISO UniProtKB:P01024 (MGI:3692807|PMID:17028856) RGD PMID:17028856 MGI:3692807 NCBI chr13:51,422,592...51,491,476
Ensembl chr13:51,422,592...51,491,502
JBrowse link
G Itgam integrin subunit alpha M enables ISO UniProtKB:P01027 (MGI:5905548|PMID:20199584) RGD PMID:20199584 MGI:5905548 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb2 integrin subunit beta 2 enables ISO UniProtKB:P01027 (MGI:5905548|PMID:20199584) RGD PMID:20199584 MGI:5905548 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Phb1 prohibitin 1 enables ISO (PMID:17070910) RGD PMID:17070910 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 enables ISO
IBA
UniProtKB:P01024 (PMID:17051150)
PMID:21873635
RGD PMID:17051150 PMID:21873635 RGD:13792537 NCBI chr  X:61,144,926...61,170,212
Ensembl chr  X:61,144,928...61,170,212
JBrowse link
complement component C4b binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Masp2 MBL associated serine protease 2 enables ISO
IEA
(PMID:22949645)
GO_REF:0000107
RGD
Ensembl
PMID:22949645 GO_REF:0000107 NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
JBrowse link
complement component C5a binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5ar1 complement C5a receptor 1 IDA RGD PMID:15292245 RGD:2303020 NCBI chr 1:76,948,622...76,959,826 JBrowse link

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Term Annotations click to browse term
  molecular_function 19910
    binding 16997
      protein binding 14384
        complement binding 24
          complement component C1q complex binding 9
          complement component C3a binding 2
          complement component C3b binding 6
          complement component C3d binding 0
          complement component C3dg binding 0
          complement component C4b binding 1
          complement component C5a binding 1
          complement component iC3b binding 0
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