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ONTOLOGY REPORT - ANNOTATIONS

Term:epithelial to mesenchymal transition
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Accession:GO:0001837 term browser browse the term
Definition:A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
Synonyms:exact_synonym: EMT;   epithelial-mesenchymal transition;   mesenchymal cell differentiation from epithelial cell


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epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKNA AT-hook transcription factor involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:254,942,874...255,004,453
Ensembl chr 1:254,945,239...254,987,764 		JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15110716) MGI
Ensembl		 PMID:15110716 GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G CUL7 cullin 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,097,848...38,116,041
Ensembl chr 7:38,097,854...38,115,822 		JBrowse link
G DACT3 dishevelled binding antagonist of beta catenin 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23580654) Ensembl
MGI		 PMID:23580654 GO_REF:0000107 NCBI chr 6:52,543,737...52,554,258
Ensembl chr 6:52,543,580...52,553,991 		JBrowse link
G DDX17 DEAD-box helicase 17 involved_in ISO (PMID:24910439) UniProt PMID:24910439 NCBI chr 5:9,485,792...9,505,157
Ensembl chr 5:9,485,702...9,505,157 		JBrowse link
G DDX5 DEAD-box helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:14,571,712...14,580,740
Ensembl chr12:14,571,951...14,580,742 		JBrowse link
G DLG5 discs large MAGUK scaffold protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:80,249,693...80,377,496
Ensembl chr14:80,249,697...80,377,064 		JBrowse link
G ENG endoglin involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,309,400...268,343,783 		JBrowse link
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:31,159,214...31,295,891
Ensembl chr15:31,159,223...31,295,893 		JBrowse link
G FAM83D family with sequence similarity 83 member D involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:41,868,982...41,892,222
Ensembl chr17:41,868,976...41,892,220 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO RGD PMID:7803853 RGD:632663 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425 		JBrowse link
G FLNA filamin A acts_upstream_of_or_within ISO (PMID:21709252) MGI PMID:21709252 NCBI chr  X:124,889,934...124,915,000
Ensembl chr  X:124,890,162...124,914,992 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G HMGA2 high mobility group AT-hook 2 involved_in ISO (PMID:18832382) UniProt PMID:18832382 NCBI chr 5:30,188,521...30,329,635 JBrowse link
G HNRNPAB heterogeneous nuclear ribonucleoprotein A/B involved_in ISO (MGI:3698386|PMID:17273560) HGNC-UCL PMID:17273560 MGI:3698386 NCBI chr 2:80,186,998...80,194,155 JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070 		JBrowse link
G LIMS1 LIM zinc finger domain containing 1 NOT|involved_in ISO (PMID:20926685) UniProt PMID:20926685 NCBI chr 3:47,607,737...47,704,921
Ensembl chr 3:47,606,230...47,672,884 		JBrowse link
G LOC100359361 high mobility group AT-hook 2-like involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:191,094,785...191,105,394 JBrowse link
G LOXL2 lysyl oxidase like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:7,435,861...7,540,699
Ensembl chr14:7,435,867...7,540,704 		JBrowse link
G LOXL3 lysyl oxidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:68,498,114...68,516,829
Ensembl chr 3:68,498,189...68,517,445 		JBrowse link
G MIR326 microRNA mir-326 involved_in ISO (PMID:24279830) BHF-UCL PMID:24279830 NCBI chr 9:9,581,944...9,582,034
Ensembl chr 9:9,581,944...9,582,034 		JBrowse link
G MSX1 msh homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:5,628,381...5,632,375
Ensembl chr 8:5,628,380...5,632,607 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 involved_in ISO (MGI:6781126|PMID:28098160) UniProt PMID:28098160 MGI:6781126 NCBI chr 9:40,628,602...40,960,605
Ensembl chr 9:40,628,631...40,960,591 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (PMID:15339668) MGI PMID:15339668 NCBI chr 1:145,940,099...146,002,897
Ensembl chr 1:145,911,046...146,008,139 		JBrowse link
G NOG noggin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:32,891,321...32,892,206
Ensembl chr12:32,891,321...32,892,206 		JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14701881) Ensembl
MGI		 PMID:14701881 GO_REF:0000107
G NOTCH4 notch receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:24,231,293...24,256,281
Ensembl chr 7:24,231,293...24,256,281 		JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15339668) Ensembl
MGI		 PMID:15339668 GO_REF:0000107 NCBI chr 3:74,004,620...74,068,173
Ensembl chr 3:74,000,517...74,068,172 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14701881) Ensembl
MGI		 PMID:14701881 GO_REF:0000107 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,754 		JBrowse link
G RFLNB refilin B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21709252) Ensembl
MGI		 PMID:21709252 GO_REF:0000107 NCBI chr12:47,307,657...47,316,652
Ensembl chr12:47,307,637...47,314,589 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:106,163,899...106,314,998
Ensembl chr 6:106,163,989...106,314,944 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:3513217|PMID:15464581) BHF-UCL PMID:15464581 MGI:3513217 NCBI chr 3:125,353,063...125,493,368
Ensembl chr 3:125,352,920...125,493,362 		JBrowse link
G SDHAF2 succinate dehydrogenase complex assembly factor 2 acts_upstream_of ISO (PMID:23983127) MGI PMID:23983127 NCBI chr 2:10,074,965...10,088,185
Ensembl chr 2:10,072,920...10,088,117 		JBrowse link
G SLC39A10 solute carrier family 39 member 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:99,584,830...99,724,621
Ensembl chr15:99,584,872...99,724,611 		JBrowse link
G SLC39A6 solute carrier family 39 member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:119,861,853...119,885,836
Ensembl chr 6:119,861,846...119,885,378 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:51,546,446...51,552,498
Ensembl chr17:51,546,477...51,552,499 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17916597) Ensembl
MGI		 PMID:17916597 GO_REF:0000107 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,880...79,268,475 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:15096597) UniProt
MGI
Ensembl		 PMID:15096597 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
G SP6 Sp6 transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:24,100,769...24,106,828
Ensembl chr12:24,100,801...24,106,792 		JBrowse link
G TGFB1 transforming growth factor beta 1 acts_upstream_of
involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:28373289)
(PMID:29529050)		 RGD
BHF-UCL
UniProt
MGI		 PMID:10504497 PMID:28373289 PMID:29529050 GO_REF:0000024 RGD:1578678 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in ISS
IEA
IBA		 (PMID:1333192) BHF-UCL
TreeGrafter
GO_Central
Ensembl		 PMID:1333192 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,110,072...125,316,796 		JBrowse link
G TGFBR3L transforming growth factor beta receptor 3 like involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:71,294,960...71,298,172
Ensembl chr 2:71,294,968...71,297,927 		JBrowse link
G TRIM28 tripartite motif containing 28 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:63,094,382...63,101,532
Ensembl chr 6:63,094,648...63,101,531 		JBrowse link
G TRIP10 thyroid hormone receptor interactor 10 ISO RGD PMID:23819628 RGD:11535143 NCBI chr 2:72,406,500...72,416,146
Ensembl chr 2:72,406,505...72,416,138 		JBrowse link
G WNT11 Wnt family member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25813538) Ensembl
MGI		 PMID:25813538 GO_REF:0000107 NCBI chr 9:10,413,182...10,435,158
Ensembl chr 9:10,413,263...10,435,100 		JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:12841867) UniProt PMID:12841867 NCBI chr 6:80,110,238...80,138,165 JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM15 ADAM metallopeptidase domain 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19156209) Ensembl
MGI		 PMID:19156209 GO_REF:0000107 NCBI chr 4:94,736,639...94,748,093
Ensembl chr 4:94,736,646...94,748,098 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chr 4:56,859,640...56,863,807
Ensembl chr 4:56,859,663...56,863,788 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:37,219,887...37,231,321
Ensembl chr 1:37,219,883...37,231,385 		JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:95,442,655...95,459,597
Ensembl chr 6:95,442,661...95,459,575 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107
G RTN4 reticulon 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19156209) Ensembl
MGI		 PMID:19156209 GO_REF:0000107 NCBI chr 3:86,180,022...86,252,126
Ensembl chr 3:86,180,022...86,252,126 		JBrowse link
G TBX3 T-box transcription factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:37,582,704...37,596,767
Ensembl chr14:37,582,822...37,596,766 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in ISS AgBase GO_REF:0000024 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,110,072...125,316,796 		JBrowse link
G WNT16 Wnt family member 16 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19156209) Ensembl
MGI		 PMID:19156209 GO_REF:0000107 NCBI chr18:25,621,802...25,633,730
Ensembl chr18:25,621,794...25,633,731 		JBrowse link
G WNT2 Wnt family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20159597) Ensembl
MGI		 PMID:20159597 GO_REF:0000107 NCBI chr18:28,945,825...28,993,969
Ensembl chr18:28,946,326...28,993,961 		JBrowse link
endocardial cushion to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 NOT|involved_in ISO (MGI:2674189|PMID:12941632) BHF-UCL PMID:12941632 MGI:2674189 NCBI chr 5:17,267,483...17,284,155
Ensembl chr 5:17,268,130...17,286,276 		JBrowse link
G ENG endoglin NOT|involved_in ISO (MGI:2674189|PMID:12941632) BHF-UCL PMID:12941632 MGI:2674189 NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,309,400...268,343,783 		JBrowse link
G SHAS2 hyaluronan synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:17,583,154...17,613,524
Ensembl chr 4:17,596,492...17,615,480 		JBrowse link
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EFNA1 ephrin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:94,666,457...94,673,442
Ensembl chr 4:94,666,460...94,674,071 		JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO (PMID:15680351) MGI PMID:15680351 NCBI chr 4:56,859,640...56,863,807
Ensembl chr 4:56,859,663...56,863,788 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15680351) Ensembl
MGI		 PMID:15680351 GO_REF:0000107 NCBI chr 1:37,219,887...37,231,321
Ensembl chr 1:37,219,883...37,231,385 		JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR21 microRNA mir-21 involved_in ISO (PMID:23441172) BHF-UCL PMID:23441172 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358 		JBrowse link
G PDCD4 programmed cell death 4 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr14:121,271,824...121,334,767
Ensembl chr14:121,305,629...121,338,740 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in ISO PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 8:100,449,476...100,863,780
Ensembl chr 8:100,450,266...100,863,446 		JBrowse link
epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 NOT|involved_in ISO (MGI:3814273|PMID:18924235) BHF-UCL PMID:18924235 MGI:3814273 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637 		JBrowse link
G ENG endoglin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,309,400...268,343,783 		JBrowse link
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21364285) Ensembl
MGI		 PMID:21364285 GO_REF:0000107 NCBI chr14:112,808,215...112,814,225
Ensembl chr14:112,808,162...112,814,248 		JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO (PMID:17303760) MGI PMID:17303760 NCBI chr 4:56,859,640...56,863,807
Ensembl chr 4:56,859,663...56,863,788 		JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17303760) Ensembl
MGI		 PMID:17303760 GO_REF:0000107 NCBI chr 6:95,442,655...95,459,597
Ensembl chr 6:95,442,661...95,459,575 		JBrowse link
G MSX1 msh homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18667074) Ensembl
MGI		 PMID:18667074 GO_REF:0000107 NCBI chr 8:5,628,381...5,632,375
Ensembl chr 8:5,628,380...5,632,607 		JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:18667074) MGI PMID:18667074 NCBI chr16:49,765,587...49,771,745
Ensembl chr16:49,765,910...49,771,789 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,754 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:51,546,446...51,552,498
Ensembl chr17:51,546,477...51,552,499 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (PMID:18663143) MGI PMID:18663143 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,880...79,268,475 		JBrowse link
G TMEM100 transmembrane protein 100 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25318679) Ensembl
MGI		 PMID:25318679 GO_REF:0000107 NCBI chr12:32,008,007...32,014,094
Ensembl chr12:32,008,012...32,014,009 		JBrowse link
mesodermal to mesenchymal transition involved in gastrulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in ISO (MGI:3772748|PMID:18171685) UniProt PMID:18171685 MGI:3772748 NCBI chr13:14,209,590...14,216,184
Ensembl chr13:14,209,736...14,215,797 		JBrowse link
G TASOR transcription activation suppressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:38,491,048...38,557,256
Ensembl chr13:38,492,472...38,557,193 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25813538) Ensembl
MGI		 PMID:25813538 GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
negative regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR19A microRNA mir-19a acts_upstream_of ISO (PMID:27098600) BHF-UCL PMID:27098600 NCBI chr11:60,734,939...60,735,020
Ensembl chr11:60,734,939...60,735,020 		JBrowse link
G MIR19B-1 microRNA mir-19b-1 acts_upstream_of ISO (PMID:27098600) BHF-UCL PMID:27098600 NCBI chr11:60,735,238...60,735,317
Ensembl chr11:60,735,230...60,735,328 		JBrowse link
G MIR19B-2 microRNA mir-19b-2 acts_upstream_of ISO (PMID:27098600) BHF-UCL PMID:27098600 NCBI chr  X:110,113,855...110,113,934
Ensembl chr  X:110,113,855...110,113,934 		JBrowse link
G NOG noggin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,891,321...32,892,206
Ensembl chr12:32,891,321...32,892,206 		JBrowse link
negative regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOR1 adiponectin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,660...261,859,022 		JBrowse link
G DACT3 dishevelled binding antagonist of beta catenin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23580654) Ensembl
MGI		 PMID:23580654 GO_REF:0000107 NCBI chr 6:52,543,737...52,554,258
Ensembl chr 6:52,543,580...52,553,991 		JBrowse link
G EFNA1 ephrin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:94,666,457...94,673,442
Ensembl chr 4:94,666,460...94,674,071 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:123,350,867...123,501,872
Ensembl chr15:123,352,816...123,503,126 		JBrowse link
G FOXA1 forkhead box A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:62,471,233...62,479,638
Ensembl chr 7:62,471,249...62,479,220 		JBrowse link
G FOXA2 forkhead box A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,997,397...30,001,704
Ensembl chr17:29,997,401...30,001,707 		JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:26451614) BHF-UCL
Ensembl		 PMID:26451614 GO_REF:0000107 NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,663...63,388,859 		JBrowse link
G HPN hepsin involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:44,608,076...44,628,044
Ensembl chr 6:44,608,071...44,628,049 		JBrowse link
G IL17RD interleukin 17 receptor D involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:38,935,631...39,006,721
Ensembl chr13:38,939,316...39,006,690 		JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:96,401,650...96,578,162
Ensembl chr 6:96,401,654...96,577,643 		JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,773,680...71,779,192
Ensembl chr 6:71,773,682...71,779,183 		JBrowse link
G MARK1 microtubule affinity regulating kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:9,980,277...10,106,507
Ensembl chr10:9,980,383...10,104,867 		JBrowse link
G MIR130A microRNA mir-130a acts_upstream_of ISO (PMID:30741461) BHF-UCL PMID:30741461 NCBI chr 2:13,296,695...13,296,773
Ensembl chr 2:13,296,695...13,296,773 		JBrowse link
G MIR142 microRNA mir-142 involved_in ISO (PMID:26572508) BHF-UCL PMID:26572508 NCBI chr12:34,609,378...34,609,457
Ensembl chr12:34,609,364...34,609,468 		JBrowse link
G MIR144 microRNA mir-144 acts_upstream_of ISO (PMID:27785072) DIBU PMID:27785072 NCBI chr12:45,088,958...45,089,033
Ensembl chr12:45,088,959...45,089,035 		JBrowse link
G MIR145 microRNA mir-145 acts_upstream_of ISO (PMID:24384875) BHF-UCL PMID:24384875 NCBI chr 2:150,580,126...150,580,211
Ensembl chr 2:150,580,126...150,580,211 		JBrowse link
G MIR18A microRNA mir-18a involved_in ISO (PMID:28131417) BHF-UCL PMID:28131417 NCBI chr11:60,734,791...60,734,882
Ensembl chr11:60,734,791...60,734,882 		JBrowse link
G MIR204 microRNA mir-204 involved_in ISO (PMID:23221074) BHF-UCL PMID:23221074 NCBI chr 1:224,065,494...224,065,602
Ensembl chr 1:224,065,494...224,065,602 		JBrowse link
G MIR29B-1 microRNA mir-29b-1 involved_in ISO (PMID:25032858) BHF-UCL PMID:25032858 NCBI chr18:18,039,629...18,039,709
Ensembl chr18:18,039,629...18,039,709 		JBrowse link
G MIR29B-2 microRNA mir-29b-2 involved_in ISO (PMID:25032858) BHF-UCL PMID:25032858 NCBI chr 9:135,019,079...135,019,162
Ensembl chr 9:135,019,075...135,019,164 		JBrowse link
G MIR31 microRNA mir-31 ISO RGD PMID:23270756 RGD:13210526 NCBI chr 1:201,198,732...201,198,809
Ensembl chr 1:201,198,732...201,198,809 		JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:63,487,200...63,491,580
Ensembl chr 7:63,487,807...63,491,575 		JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:26,417,793...26,451,707
Ensembl chr17:26,417,795...26,451,928 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:27919618) BHF-UCL PMID:27919618 NCBI chr14:99,929,590...100,021,619 JBrowse link
G SDHAF2 succinate dehydrogenase complex assembly factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23983127) MGI
Ensembl		 PMID:23983127 GO_REF:0000107 NCBI chr 2:10,074,965...10,088,185
Ensembl chr 2:10,072,920...10,088,117 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,144...75,345,921 		JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:132,903,103...133,016,725
Ensembl chr 1:132,902,304...133,015,742 		JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr 3:76,527,646...76,649,652
Ensembl chr 3:76,523,589...76,649,651 		JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr 6:47,302,211...47,312,034
Ensembl chr 6:47,298,634...47,310,181 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:100,449,476...100,863,780
Ensembl chr 8:100,450,266...100,863,446 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,153,695...52,158,766
Ensembl chr11:52,153,704...52,159,156 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (PMID:17823118) MGI PMID:17823118 NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,110,072...125,316,796 		JBrowse link
G TRIM62 tripartite motif containing 62 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24890125) Ensembl
MGI		 PMID:24890125 GO_REF:0000107 NCBI chr 6:89,406,470...89,442,794
Ensembl chr 6:89,406,478...89,442,746 		JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:20813961 RGD:11568680 NCBI chr 3:39,898,924...39,935,579
Ensembl chr 3:39,898,925...39,937,371 		JBrowse link
G USF3 upstream transcription factor family member 3 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:146,230,165...146,286,862
Ensembl chr13:146,230,180...146,282,335 		JBrowse link
G VASN vasorin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:37,961,425...37,972,477
Ensembl chr 3:37,961,432...37,972,114 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
G ZNF750 zinc finger protein 750 involved_in ISO (PMID:32042337) ARUK-UCL PMID:32042337 NCBI chr12:398,498...407,812 JBrowse link
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
negative regulation of neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FUZ fuzzy planar cell polarity protein involved_in ISO (MGI:5498583|PMID:23806618) UniProt PMID:23806618 MGI:5498583 NCBI chr 6:54,823,680...54,830,425
Ensembl chr 6:54,823,668...54,829,506 		JBrowse link
neural crest cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:81,210,750...81,279,053
Ensembl chr 8:81,209,327...81,276,853 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20130188) Ensembl
MGI		 PMID:20130188 GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSC goosecoid homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:116,099,053...116,101,153
Ensembl chr 7:116,098,327...116,101,338 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISS UniProt GO_REF:0000024 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRD chordin involved_in ISO (PMID:17685487) MGI PMID:17685487 NCBI chr13:122,266,632...122,277,513
Ensembl chr13:122,266,626...122,277,645 		JBrowse link
G KBTBD8 kelch repeat and BTB domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:48,486,919...48,499,992
Ensembl chr13:48,486,978...48,501,345 		JBrowse link
G LRP6 LDL receptor related protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:60,149,041...60,318,719
Ensembl chr 5:60,149,028...60,314,662 		JBrowse link
G NOLC1 nucleolar and coiled-body phosphoprotein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:113,154,619...113,166,922
Ensembl chr14:113,154,819...113,166,906 		JBrowse link
G PDCD6 programmed cell death 6 involved_in ISO (PMID:27716508) UniProt PMID:27716508 NCBI chr16:79,818,960...79,832,272
Ensembl chr16:79,818,958...79,835,746 		JBrowse link
G PEF1 penta-EF-hand domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:88,152,232...88,170,327
Ensembl chr 6:88,152,235...88,170,251 		JBrowse link
G RABIF RAB interacting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,869,816...24,902,981
Ensembl chr10:24,869,829...24,900,266 		JBrowse link
G RABIF RAB interacting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,859,382...24,867,141
Ensembl chr10:24,859,385...24,867,141 		JBrowse link
G TCOF1 treacle ribosome biogenesis factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:151,368,264...151,401,029
Ensembl chr 2:151,368,289...151,401,027 		JBrowse link
positive regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,749,478...64,891,653
Ensembl chr15:64,750,796...64,891,544 		JBrowse link
G EMP2 epithelial membrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:32,449,496...32,493,245
Ensembl chr 3:32,450,604...32,492,721 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in ISO PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr17:19,591,248...19,629,659
Ensembl chr17:19,591,259...19,629,641 		JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:5300829|PMID:22186728) UniProt PMID:22186728 MGI:5300829 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TWIST1 twist family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:88,286,911...88,290,131
Ensembl chr 9:88,289,407...88,290,015 		JBrowse link
positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:141,221,177...141,233,728
Ensembl chr14:141,221,198...141,232,306 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:21743278 RGD:7243870 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,120...24,221,162 		JBrowse link
G AGT angiotensinogen involved_in ISO (MGI:7444872|PMID:34615811) UniProt PMID:34615811 MGI:7444872 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G ALX1 ALX homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:96,761,683...96,785,125
Ensembl chr 5:96,763,685...96,785,165 		JBrowse link
G AXIN2 axin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,311,293...12,343,207
Ensembl chr12:12,311,298...12,343,200 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:40,053,368...40,058,590
Ensembl chr10:40,053,355...40,060,319 		JBrowse link
G BCL9L BCL9 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:46,146,519...46,175,052
Ensembl chr 9:46,146,525...46,174,589 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16314491) Ensembl
MGI		 PMID:16314491 GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637 		JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:57,567,770...57,676,516
Ensembl chr17:57,584,956...57,675,986 		JBrowse link
G COL1A1 collagen type I alpha 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G CRB2 crumbs cell polarity complex component 2 involved_in ISS
IEA		 CAFA
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:264,277,549...264,301,731
Ensembl chr 1:264,276,987...264,301,713 		JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23983127) MGI
Ensembl		 PMID:23983127 GO_REF:0000107 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,385,015...109,450,941 		JBrowse link
G FERMT2 FERM domain containing kindlin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:182,519,681...182,606,890
Ensembl chr 1:182,519,684...182,606,869 		JBrowse link
G FOXC1 forkhead box C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:837,088...840,593
Ensembl chr 7:837,171...838,805 		JBrowse link
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:7,328,839...7,330,657 JBrowse link
G GLIPR2 GLI pathogenesis related 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:236,919,821...236,943,828
Ensembl chr 1:236,919,879...236,943,823 		JBrowse link
G HDAC2 histone deacetylase 2 ISO RGD PMID:19553350 RGD:9590229 NCBI chr 1:79,867,713...79,901,597
Ensembl chr 1:79,863,094...79,901,585 		JBrowse link
G IL6 interleukin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in ISO PMID:23270756 BHF-UCL
RGD		 PMID:23270756 RGD:13210526 NCBI chr16:30,962,994...30,974,201
Ensembl chr16:30,963,000...30,973,907 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070 		JBrowse link
G LOC100152566 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase involved_in ISO (PMID:21750175)
(MGI:5545971|PMID:21750175)		 UniProt PMID:21750175 MGI:5545971 NCBI chr 7:7,382,731...7,422,199
Ensembl chr 7:7,328,214...7,422,197 		JBrowse link
G LOC110258578 interleukin-1 beta-like involved_in ISO (PMID:25204733) BHF-UCL PMID:25204733
G LOXL2 lysyl oxidase like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:7,435,861...7,540,699
Ensembl chr14:7,435,867...7,540,704 		JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 involved_in ISO (PMID:32887674) BHF-UCL PMID:32887674 NCBI chr 2:74,300,598...74,303,117
Ensembl chr 2:74,300,619...74,314,315 		JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 ISO TGFb1 RGD PMID:27488450 RGD:152995505 NCBI chr 6:71,773,680...71,779,192
Ensembl chr 6:71,773,682...71,779,183 		JBrowse link
G MDK midkine involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:16,130,787...16,133,791
Ensembl chr 2:16,130,788...16,133,510 		JBrowse link
G MIR21 microRNA mir-21 involved_in ISO (PMID:24887517) BHF-UCL PMID:24887517 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358 		JBrowse link
G MIR221 microRNA mir-221 involved_in ISO (PMID:21673316) BHF-UCL PMID:21673316 NCBI chr  X:40,571,068...40,571,137
Ensembl chr  X:40,571,068...40,571,137 		JBrowse link
G MIR222 microRNA mir-222 involved_in ISO (PMID:21673316) BHF-UCL PMID:21673316 NCBI chr  X:40,571,808...40,571,887
Ensembl chr  X:40,571,808...40,571,887 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G MYOCD myocardin involved_in ISO PMID:23270756 BHF-UCL PMID:23270756 RGD:13210526 NCBI chr12:56,931,628...57,029,258
Ensembl chr12:56,931,317...57,029,258 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107
G PDPN podoplanin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:73,019,063...73,050,000
Ensembl chr 6:73,019,057...73,049,996 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISO (PMID:26944318) BHF-UCL PMID:26944318 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054 		JBrowse link
G RGCC regulator of cell cycle involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:25,481,845...25,496,548
Ensembl chr11:25,478,879...25,496,519 		JBrowse link
G SDCBP syndecan binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:74,295,941...74,357,720
Ensembl chr 4:74,295,922...74,341,085 		JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:97,415,360...97,511,388
Ensembl chr 1:97,415,716...97,511,357 		JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:51,546,446...51,552,498
Ensembl chr17:51,546,477...51,552,499 		JBrowse link
G TBX20 T-box transcription factor 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:38,635,603...38,681,690
Ensembl chr18:38,635,617...38,678,133 		JBrowse link
G TCF7L2 transcription factor 7 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,412...123,546,417 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:18794329) UniProt
MGI		 PMID:18794329 GO_REF:0000024 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,093,275...17,099,204
Ensembl chr 3:17,090,116...17,099,020 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
G TGFB3 transforming growth factor beta 3 involved_in IEA
ISS		 Ensembl
AgBase		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:99,133,873...99,162,239
Ensembl chr 7:99,133,879...99,162,232 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:88,286,911...88,290,131
Ensembl chr 9:88,289,407...88,290,015 		JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:89,742,980...89,889,547
Ensembl chr13:89,742,886...89,889,187 		JBrowse link
G ZNF703 zinc finger protein 703 involved_in ISO (MGI:4940410|PMID:21317240) UniProt PMID:21317240 MGI:4940410 NCBI chr15:48,692,316...48,696,639
Ensembl chr15:48,692,320...48,696,644 		JBrowse link
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENG endoglin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,309,400...268,343,783 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160 		JBrowse link
regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLF aprataxin and PNKP like factor involved_in ISO (MGI:6780835|PMID:33277378) UniProt PMID:33277378 MGI:6780835 NCBI chr 3:73,752,115...73,831,158
Ensembl chr 3:73,752,118...73,831,035 		JBrowse link
G CLASP1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:23940118) UniProt PMID:23940118 NCBI chr15:29,782,613...30,042,727
Ensembl chr15:29,782,746...30,042,734 		JBrowse link
G CLASP2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:23940118) UniProt PMID:23940118 NCBI chr13:19,305,430...19,510,589
Ensembl chr13:19,305,181...19,510,585 		JBrowse link
G DAG1 dystroglycan 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:32,028,019...32,092,450
Ensembl chr13:32,029,522...32,092,450 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:127,781,357...127,784,803
Ensembl chr 1:127,781,403...127,784,843 		JBrowse link
G EPHA3 EPH receptor A3 involved_in ISO (MGI:3703403|PMID:17046737) UniProt PMID:17046737 MGI:3703403 NCBI chr13:166,592,492...166,942,791
Ensembl chr13:166,592,493...166,942,767 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:136,617,041...136,629,293
Ensembl chr 1:136,617,105...136,629,292 		JBrowse link
G MCRIP1 MAPK regulated corepressor interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,137,797...1,144,556
Ensembl chr12:1,137,816...1,144,555 		JBrowse link
G PHLDB1 pleckstrin homology like domain family B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:45,902,099...45,949,415
Ensembl chr 9:45,902,155...45,949,415 		JBrowse link
G PHLDB2 pleckstrin homology like domain family B member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:147,778,420...148,025,943
Ensembl chr13:147,778,370...147,879,794 		JBrowse link
G PHLDB2 pleckstrin homology like domain family B member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:148,033,712...148,087,766
Ensembl chr13:148,033,704...148,087,744 		JBrowse link
G POFUT2 protein O-fucosyltransferase 2 acts_upstream_of_or_within ISO (PMID:20637190) MGI PMID:20637190 NCBI chr13:207,801,101...207,818,138 JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:4,732,575...4,883,386
Ensembl chr 1:4,735,514...4,883,392 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,514,267...98,542,382 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in ISS AgBase GO_REF:0000024 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:194,774,495...195,235,750
Ensembl chr13:194,774,497...195,005,089 		JBrowse link
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB1 transforming growth factor beta 1 NOT|involved_in ISO (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TGFB3 transforming growth factor beta 3 NOT|involved_in ISO (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr 7:99,133,873...99,162,239
Ensembl chr 7:99,133,879...99,162,232 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr14:87,743,270...87,891,790
Ensembl chr14:87,742,459...87,891,790 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17813
    cellular process 16883
      cellular developmental process 4526
        cell differentiation 4525
          mesenchymal cell differentiation 276
            epithelial to mesenchymal transition 185
              cardiac epithelial to mesenchymal transition + 40
              clearance of cells from fusion plate by epithelial to mesenchymal transition 0
              epicardial cell to mesenchymal cell transition 0
              mesodermal to mesenchymal transition involved in gastrulation + 3
              negative regulation of epithelial to mesenchymal transition + 47
              neural crest formation + 16
              positive regulation of epithelial to mesenchymal transition + 58
              regulation of epithelial to mesenchymal transition + 119
Path 2
Term Annotations click to browse term
  biological_process 17813
    developmental process 6722
      anatomical structure development 6316
        tissue development 2231
          mesenchyme development 339
            mesenchymal cell differentiation 276
              epithelial to mesenchymal transition 185
                cardiac epithelial to mesenchymal transition + 40
                clearance of cells from fusion plate by epithelial to mesenchymal transition 0
                epicardial cell to mesenchymal cell transition 0
                mesodermal to mesenchymal transition involved in gastrulation + 3
                negative regulation of epithelial to mesenchymal transition + 47
                neural crest formation + 16
                positive regulation of epithelial to mesenchymal transition + 58
                regulation of epithelial to mesenchymal transition + 119
paths to the root