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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial to mesenchymal transition
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Accession:GO:0001837 term browser browse the term
Definition:A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
Synonyms:exact_synonym: EMT;   epithelial-mesenchymal transition;   mesenchymal cell differentiation from epithelial cell


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epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akna AT-hook transcription factor involved_in ISO (MGI:6294240|PMID:30787442) RGD PMID:30787442 MGI:6294240 NCBI chr 5:79,184,087...79,232,370
Ensembl chr 5:79,184,088...79,222,687
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3640731|PMID:16730346), (MGI:5299248|PMID:21983003)
(PMID:15110716), (PMID:18184661)
UniProt
RGD
PMID:15110716 PMID:16730346 PMID:18184661 PMID:21983003 GO_REF:0000024 MGI:3640731 MGI:5299248 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Cul7 cullin 7 involved_in ISO
ISS
(PMID:20139075)
GO_REF:0000024
RGD
UniProt
PMID:20139075 GO_REF:0000024 NCBI chr 9:16,629,491...16,643,527
Ensembl chr 9:16,629,401...16,643,182
JBrowse link
G Ddx17 DEAD-box helicase 17 involved_in ISO (PMID:24910439) RGD PMID:24910439 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:24910439) RGD PMID:24910439 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO (PMID:28169360) RGD PMID:28169360 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
G Eng endoglin involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 involved_in ISO MGI:3578147 (MGI:3714667|PMID:17507402), (MGI:3821807|PMID:18794329) RGD PMID:17507402 PMID:18794329 MGI:3714667 MGI:3821807 NCBI chr13:35,622,472...35,673,449
Ensembl chr13:35,580,098...35,668,968
JBrowse link
G Fam83d family with sequence similarity 83, member D involved_in ISO (PMID:24344117) RGD PMID:24344117 NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 involved_in ISO
IEA
(PMID:26451614)
GO_REF:0000107
RGD
Ensembl
PMID:26451614 GO_REF:0000107 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IDA RGD PMID:7803853 RGD:632663 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Flna filamin A acts_upstream_of_or_within ISO MGI:1923816 (MGI:5085960|PMID:21709252) RGD PMID:21709252 MGI:5085960 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO
ISS
(PMID:15448698)
GO_REF:0000024
RGD
UniProt
PMID:15448698 GO_REF:0000024 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA
ISO
GO_REF:0000107
(MGI:3772289|PMID:18037992)
Ensembl
RGD
PMID:18037992 GO_REF:0000107 MGI:3772289 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS
(PMID:18832382)
GO_REF:0000024
RGD
UniProt
PMID:18832382 GO_REF:0000024 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B involved_in ISS
ISO
GO_REF:0000024
(MGI:3698386|PMID:17273560)
HGNC
RGD
HGNC-UCL
PMID:17273560 GO_REF:0000024 MGI:3698386 NCBI chr10:34,955,713...34,961,662
Ensembl chr10:34,955,716...34,961,608
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:2683382|PMID:14691138)
Ensembl
RGD
PMID:14691138 GO_REF:0000107 MGI:2683382 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lims1 LIM zinc finger domain containing 1 NOT
NOT|involved_in
ISO (PMID:20926685) RGD PMID:20926685 NCBI chr20:27,895,981...28,004,767
Ensembl chr20:27,954,433...28,002,082
JBrowse link
G LOC103689931 heterogeneous nuclear ribonucleoprotein A/B involved_in ISS GO_REF:0000024 HGNC
HGNC-UCL
GO_REF:0000024 NCBI chr10:37,049,400...37,055,348
Ensembl chr10:37,049,677...37,055,282
Ensembl chr10:37,049,677...37,055,282
JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16096638)
Ensembl
UniProt
RGD
PMID:16096638 GO_REF:0000024 GO_REF:0000107 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234
JBrowse link
G Loxl3 lysyl oxidase-like 3 involved_in ISO (PMID:16096638) RGD PMID:16096638 NCBI chr 4:113,866,782...113,883,713
Ensembl chr 4:113,866,804...113,883,477
JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (MGI:4418636|PMID:11023873) RGD PMID:11023873 MGI:4418636 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (MGI:3053252|PMID:15339668) RGD PMID:15339668 MGI:3053252 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nog noggin involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3783944|PMID:17218603)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17218603 GO_REF:0000024 GO_REF:0000107 MGI:3783944 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within
involved_in
ISO (PMID:17984306)
MGI:1857230 (MGI:3027664|PMID:14701881)
RGD PMID:14701881 PMID:17984306 MGI:3027664 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Notch4 notch receptor 4 involved_in ISO (PMID:17984306) RGD PMID:17984306 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha acts_upstream_of_or_within ISO MGI:3044031 (MGI:3053252|PMID:15339668) RGD PMID:15339668 MGI:3053252 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:1857411 (MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:3027664 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Rflnb refilin B acts_upstream_of_or_within ISO MGI:95556 (MGI:5085960|PMID:21709252) RGD PMID:21709252 MGI:5085960 NCBI chr10:64,196,103...64,202,380
Ensembl chr10:64,196,127...64,202,380
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P70336 (MGI:3513217|PMID:15464581)
Ensembl
RGD
PMID:15464581 GO_REF:0000107 MGI:3513217 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO UniProtKB:P70335 (MGI:3513217|PMID:15464581) RGD PMID:15464581 MGI:3513217 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in TAS
ISO
(MGI:1352954|PMID:10655586), (MGI:2153695|PMID:11689706), (MGI:5294539|PMID:18832382)
(PMID:16096638)
RGD PMID:10655586 PMID:11689706 PMID:16096638 PMID:18832382, PMID:15155580 MGI:1352954 MGI:2153695 MGI:5294539, RGD:1302246 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within
involved_in
ISO (PMID:17984306), (PMID:9182671)
MGI:2447175 (MGI:3762325|PMID:17916597)
(MGI:892810|PMID:9182671)
MGI:2447175 (MGI:3762325|PMID:17916597), (MGI:892810|PMID:9182671)
RGD PMID:9182671 PMID:17916597 PMID:17984306 MGI:3762325 MGI:892810 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within
involved_in
ISS
ISO
GO_REF:0000024
MGI:2429649 (MGI:3041362|PMID:15096597)
UniProt
RGD
PMID:15096597 GO_REF:0000024 MGI:3041362 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in IDA
ISO
(PMID:25893292), (PMID:29529050) RGD PMID:25893292 PMID:29529050, PMID:10504497 RGD:1578678 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:10092230), (PMID:18223299)
AgBase
RGD
PMID:10092230 PMID:18223299 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:15761148) RGD PMID:15761148 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO
IBA
(PMID:18184661)
PMID:21873635
RGD PMID:18184661, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:2,540,494...2,545,315
Ensembl chr12:2,542,612...2,545,740
JBrowse link
G Trim28 tripartite motif-containing 28 involved_in ISS
ISO
GO_REF:0000024
(MGI:3698386|PMID:17273560)
HGNC
RGD
HGNC-UCL
PMID:17273560 GO_REF:0000024 MGI:3698386 NCBI chr 1:65,544,369...65,551,043
Ensembl chr 1:65,544,373...65,551,043
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23819628 RGD:11535143 NCBI chr 9:9,689,214...9,702,353
Ensembl chr 9:9,689,475...9,702,306
JBrowse link
G Wnt11 Wnt family member 11 acts_upstream_of_or_within ISO MGI:98958 (MGI:5634837|PMID:25813538) RGD PMID:25813538 MGI:5634837 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt4 Wnt family member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:12841867)
Ensembl
RGD
PMID:12841867 GO_REF:0000107 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:12841867) RGD PMID:12841867 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO
ISS
(PMID:17072303)
GO_REF:0000024
RGD
UniProt
PMID:17072303 GO_REF:0000024 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:17072303) RGD PMID:17072303 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 acts_upstream_of_or_within ISO (MGI:4458867|PMID:19156209) RGD PMID:19156209 MGI:4458867 NCBI chr 2:188,661,831...188,672,337
Ensembl chr 2:188,661,699...188,672,247
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA
(PMID:18184661)
GO_REF:0000107
RGD
Ensembl
PMID:18184661 GO_REF:0000107 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905
JBrowse link
G LOC103690035 TGF-beta receptor type-1-like involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:64,565,358...64,585,219
Ensembl chr 5:64,566,804...64,584,309
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Olfm1 olfactomedin 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 3:6,761,031...6,798,739
Ensembl chr 3:6,773,813...6,798,737
JBrowse link
G Rtn4 reticulon 4 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
(MGI:4458867|PMID:19156209)
Ensembl
RGD
PMID:19156209 GO_REF:0000107 MGI:4458867 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
G Tbx3 T-box transcription factor 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:22130515)
Ensembl
RGD
PMID:22130515 GO_REF:0000107 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
ISS
(PMID:10092230)
GO_REF:0000024
RGD
UniProt
PMID:10092230 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (PMID:18184661) RGD PMID:18184661 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Wnt16 Wnt family member 16 acts_upstream_of_or_within ISO (MGI:4458867|PMID:19156209) RGD PMID:19156209 MGI:4458867 NCBI chr 4:49,369,246...49,388,156
Ensembl chr 4:49,369,296...49,379,703
JBrowse link
G Wnt2 Wnt family member 2 acts_upstream_of_or_within ISO MGI:4361155 (MGI:4439199|PMID:20159597) RGD PMID:20159597 MGI:4439199 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420
JBrowse link
endocardial cushion to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 NOT
NOT|involved_in
ISO (MGI:2674189|PMID:12941632) RGD PMID:12941632 MGI:2674189 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Eng endoglin NOT
NOT|involved_in
ISO (MGI:2674189|PMID:12941632) RGD PMID:12941632 MGI:2674189 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Has2 hyaluronan synthase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:1861536|PMID:10930438)
UniProt
RGD
PMID:10930438 GO_REF:0000024 MGI:1861536 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Erg ETS transcription factor ERG acts_upstream_of_or_within ISO MGI:5443838 (MGI:5442628|PMID:22932696) RGD PMID:22932696 MGI:5442628 NCBI chr11:35,645,317...35,749,637
Ensembl chr11:35,646,116...35,749,594
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1341884 (MGI:3530185|PMID:15680351) RGD PMID:15680351 MGI:3530185 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:1341800 (MGI:3530185|PMID:15680351) RGD PMID:15680351 MGI:3530185 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd4 programmed cell death 4 involved_in IGI PMID:23441172 BHF-UCL PMID:23441172, PMID:23441172 RGD:10400865, RGD:10400865 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in IGI PMID:23441172 BHF-UCL PMID:23441172, PMID:23441172 RGD:10400865, RGD:10400865 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331
JBrowse link
epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 NOT
NOT|involved_in
ISO (MGI:3814273|PMID:18924235) RGD PMID:18924235 MGI:3814273 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Eng endoglin involved_in ISO (MGI:4368063|PMID:19703439) RGD PMID:19703439 MGI:4368063 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within
involved_in
ISO (MGI:4359139|PMID:19509466), (MGI:5002778|PMID:21364285)
(MGI:5002778|PMID:21364285)
RGD PMID:19509466 PMID:21364285 MGI:4359139 MGI:5002778 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1860511 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like acts_upstream_of_or_within ISO MGI:1341800 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905
JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:97169 (MGI:3810851|PMID:18667074) RGD PMID:18667074 MGI:3810851 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:97168 (MGI:3810851|PMID:18667074)
Ensembl
RGD
PMID:18667074 GO_REF:0000107 MGI:3810851 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:3027664 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:3027664 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:4946551|PMID:21330551)
Ensembl
RGD
PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO UniProtKB:Q3UZ96 (MGI:3808643|PMID:18663143) RGD PMID:18663143 MGI:3808643 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO MGI:2447175 (MGI:3808643|PMID:18663143) RGD PMID:18663143 MGI:3808643 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within ISO MGI:5432904 (MGI:5613881|PMID:25318679) RGD PMID:25318679 MGI:5613881 NCBI chr10:77,537,340...77,543,710
Ensembl chr10:77,537,340...77,543,192
JBrowse link
mesodermal to mesenchymal transition involved in gastrulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in ISO (MGI:3772748|PMID:18171685) RGD PMID:18171685 MGI:3772748 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
JBrowse link
G Tasor transcription activation suppressor involved_in IEA
ISO
GO_REF:0000107
(MGI:6109647|PMID:28839193)
Ensembl
RGD
PMID:28839193 GO_REF:0000107 MGI:6109647 NCBI chr16:3,050,506...3,108,168
Ensembl chr16:3,051,449...3,105,531
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:101948 (MGI:5634837|PMID:25813538)
Ensembl
RGD
PMID:25813538 GO_REF:0000107 MGI:5634837 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
negative regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 involved_in ISO (PMID:23776679) RGD PMID:23776679 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:20080667), (PMID:20154697)
UniProt
Ensembl
RGD
PMID:20080667 PMID:20154697 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 acts_upstream_of_or_within ISO MGI:5515616 (MGI:5503293|PMID:23580654) RGD PMID:23580654 MGI:5503293 NCBI chr 1:78,800,754...78,812,483
Ensembl chr 1:78,800,754...78,812,483
JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Foxa1 forkhead box A1 involved_in ISO
IEA
(PMID:20160041)
GO_REF:0000107
RGD
Ensembl
PMID:20160041 GO_REF:0000107 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxa2 forkhead box A2 involved_in ISO
IEA
(PMID:20160041)
GO_REF:0000107
RGD
Ensembl
PMID:20160041 GO_REF:0000107 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of ISO (PMID:26451614) RGD PMID:26451614 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Hpn hepsin involved_in IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:19843851)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19843851, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967
JBrowse link
G Il17rd interleukin 17 receptor D involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in ISO (PMID:24627487) RGD PMID:24627487 NCBI chr18:63,717,423...64,045,224
Ensembl chr18:63,882,610...64,044,023
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:19443654) RGD PMID:19443654 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19293183)
Ensembl
RGD
PMID:19293183 GO_REF:0000107 NCBI chr 6:77,418,096...77,423,383
Ensembl chr 6:77,418,096...77,421,286
JBrowse link
G Ovol2 ovo-like zinc finger 2 involved_in ISO (MGI:5574425|PMID:24735879), (MGI:6284898|PMID:28455959) RGD PMID:24735879 PMID:28455959 MGI:5574425 MGI:6284898 NCBI chr 3:138,433,990...138,464,511
Ensembl chr 3:138,433,990...138,462,063
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 involved_in ISO (PMID:23687415) RGD PMID:23687415 NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:20080667) RGD PMID:20080667 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:27919618) RGD PMID:27919618 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 acts_upstream_of_or_within
involved_in
ISO (PMID:23983127)
(MGI:5529200|PMID:23983127)
RGD PMID:23983127 MGI:5529200 NCBI chr 1:226,543,671...226,572,414
Ensembl chr 1:226,547,531...226,572,349
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19095296)
Ensembl
RGD
PMID:19095296 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:19095296) RGD PMID:19095296 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 3:108,795,337...108,861,650
Ensembl chr 3:108,795,235...108,857,556
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414689|PMID:25576668)
UniProt
RGD
PMID:25576668 GO_REF:0000024 MGI:6414689 NCBI chr14:104,268,362...104,290,206
Ensembl chr14:104,191,517...104,290,456
JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 1:88,101,213...88,112,719
Ensembl chr 1:88,103,719...88,112,683
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr15:90,172,769...90,177,823
Ensembl chr15:90,172,975...90,175,802
JBrowse link
G Strap serine/threonine kinase receptor associated protein involved_in ISO (PMID:23687415) RGD PMID:23687415 NCBI chr 4:171,730,629...171,744,877
Ensembl chr 4:171,730,635...171,745,377
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (MGI:3762085|PMID:17823118) RGD PMID:17823118 MGI:3762085 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Trim62 tripartite motif-containing 62 acts_upstream_of_or_within ISO MGI:5538538 (MGI:5585203|PMID:24890125) RGD PMID:24890125 MGI:5585203 NCBI chr 5:147,068,725...147,099,024
Ensembl chr 5:147,069,616...147,095,242
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:20813961 RGD:11568680 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Usf3 upstream transcription factor family member 3 involved_in ISO (PMID:28011713) RGD PMID:28011713 NCBI chr11:61,427,140...61,499,668
Ensembl chr11:61,432,064...61,499,557
JBrowse link
G Vasn vasorin involved_in ISO (PMID:21170088) RGD PMID:21170088 NCBI chr10:11,121,041...11,131,548
Ensembl chr10:11,121,041...11,131,548
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Znf750 zinc finger protein 750 involved_in ISO
IEA
(PMID:32042337)
GO_REF:0000107
RGD
Ensembl
PMID:32042337 GO_REF:0000107 NCBI chr10:110,698,581...110,701,222
Ensembl chr10:110,698,891...110,701,137
JBrowse link
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nog noggin involved_in IEA
ISO
GO_REF:0000107
(MGI:3783944|PMID:17218603)
Ensembl
RGD
PMID:17218603 GO_REF:0000107 MGI:3783944 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
negative regulation of neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fuz fuzzy planar cell polarity protein involved_in ISS
ISO
GO_REF:0000024
(MGI:5498583|PMID:23806618)
UniProt
RGD
PMID:23806618 GO_REF:0000024 MGI:5498583 NCBI chr 1:100,891,832...100,896,811
Ensembl chr 1:100,891,866...100,896,807
JBrowse link
neural crest cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:3045799 (MGI:4437369|PMID:20130188)
Ensembl
RGD
PMID:20130188 GO_REF:0000107 MGI:4437369 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsc goosecoid homeobox involved_in ISO (PMID:24290375) RGD PMID:24290375 NCBI chr 6:128,147,181...128,149,220
Ensembl chr 6:128,147,181...128,149,220
JBrowse link
neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kbtbd8 kelch repeat and BTB domain containing 8 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:26399832)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:26399832 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:127,164,728...127,177,537
Ensembl chr 4:127,164,453...127,177,477
JBrowse link
G Klhl12 kelch-like family member 12 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:27716508)
Ensembl
UniProt
RGD
PMID:27716508 GO_REF:0000024 GO_REF:0000107 NCBI chr13:51,280,933...51,314,753
Ensembl chr13:51,282,684...51,314,797
JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in ISO
IBA
(PMID:11029007)
PMID:21873635
RGD PMID:11029007, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 involved_in ISO
ISS
(PMID:26399832)
GO_REF:0000024
RGD
UniProt
PMID:26399832 GO_REF:0000024 NCBI chr 1:265,829,055...265,839,819
Ensembl chr 1:265,829,108...265,839,818
JBrowse link
G Pdcd6 programmed cell death 6 involved_in ISO
ISS
(PMID:27716508)
GO_REF:0000024
RGD
UniProt
PMID:27716508 GO_REF:0000024 NCBI chr 1:31,576,183...31,591,852
Ensembl chr 1:31,576,183...31,591,849
JBrowse link
G Pef1 penta-EF hand domain containing 1 involved_in ISO
ISS
(PMID:27716508)
GO_REF:0000024
RGD
UniProt
PMID:27716508 GO_REF:0000024 NCBI chr 5:148,320,610...148,343,876
Ensembl chr 5:148,320,438...148,343,886
JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 involved_in ISO (PMID:26399832) RGD PMID:26399832 NCBI chr18:56,081,863...56,115,719
Ensembl chr18:56,082,195...56,115,593
JBrowse link
positive regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag1 jagged canonical Notch ligand 1 involved_in IGI PMID:20951801 BHF-UCL PMID:20951801, PMID:20951801 RGD:13601997, RGD:13601997 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Notch1 notch receptor 1 involved_in IGI PMID:20951801 BHF-UCL PMID:20951801, PMID:20951801 RGD:13601997, RGD:13601997 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:21743278 RGD:7243870 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Alx1 ALX homeobox 1 involved_in ISO
ISS
(PMID:23288509)
GO_REF:0000024
RGD
UniProt
PMID:23288509 GO_REF:0000024 NCBI chr 7:44,751,865...44,771,458
Ensembl chr 7:44,751,873...44,771,458
JBrowse link
G Axin2 axin 2 involved_in ISO
IEA
(PMID:17072303)
GO_REF:0000107
RGD
Ensembl
PMID:17072303 GO_REF:0000107 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO (PMID:19328798) RGD PMID:19328798 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bcl9l BCL9 like involved_in ISO (PMID:19328798) RGD PMID:19328798 NCBI chr 8:48,805,684...48,835,794
Ensembl chr 8:48,805,684...48,834,312
JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:20890042)
MGI:3583785 (MGI:3611958|PMID:16314491)
GO_REF:0000107
RGD
Ensembl
PMID:16314491 PMID:20890042 GO_REF:0000107 MGI:3611958 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P23359 (MGI:5502250|PMID:23863481)
Ensembl
RGD
PMID:23863481 GO_REF:0000107 MGI:5502250 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO UniProtKB:P21275 (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Col1a1 collagen type I alpha 1 chain involved_in ISO (PMID:20018240) RGD PMID:20018240 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Crb2 crumbs cell polarity complex component 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5296388|PMID:22072575), (MGI:5823085|PMID:27870829)
UniProt
RGD
PMID:22072575 PMID:27870829 GO_REF:0000024 MGI:5296388 MGI:5823085 NCBI chr 3:22,037,812...22,061,247
Ensembl chr 3:22,038,357...22,058,871
JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO UniProtKB:Q9NX18 (PMID:23983127) RGD PMID:23983127 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:5442513|PMID:15734730)
Ensembl
RGD
PMID:15734730 GO_REF:0000107 MGI:5442513 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:20154697) RGD PMID:20154697 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO
IEA
(PMID:24226523)
GO_REF:0000107
RGD
Ensembl
PMID:24226523 GO_REF:0000107 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (PMID:22991501) RGD PMID:22991501 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) involved_in ISO (PMID:21750175)
(MGI:5545971|PMID:21750175)
RGD PMID:21750175 MGI:5545971 NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
JBrowse link
G Glipr2 GLI pathogenesis-related 2 involved_in ISO (PMID:23516513) RGD PMID:23516513 NCBI chr 5:59,415,415...59,446,732
Ensembl chr 5:59,416,076...59,446,647
JBrowse link
G Hdac2 histone deacetylase 2 IMP RGD PMID:19553350 RGD:9590229 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Il1b interleukin 1 beta involved_in IEA
ISO
GO_REF:0000107
(PMID:25204733)
Ensembl
RGD
PMID:25204733 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:25916550) RGD PMID:25916550 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IMP PMID:23270756 BHF-UCL PMID:23270756, PMID:23270756 RGD:13210526, RGD:13210526 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:20018240)
Ensembl
RGD
PMID:20018240 GO_REF:0000107 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:24239292)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24239292 GO_REF:0000024 GO_REF:0000107 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234
JBrowse link
G Mdk midkine involved_in ISS
ISO
GO_REF:0000024
(PMID:18469519)
UniProt
RGD
PMID:18469519 GO_REF:0000024 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:27919618) RGD PMID:27919618 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myocd myocardin involved_in IMP PMID:23270756 BHF-UCL PMID:23270756, PMID:23270756 RGD:13210526, RGD:13210526 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:4837019 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Olfm1 olfactomedin 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 3:6,761,031...6,798,739
Ensembl chr 3:6,773,813...6,798,737
JBrowse link
G Pdpn podoplanin involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17046996), (PMID:21376833)
UniProt
RGD
PMID:17046996 PMID:21376833, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19158077), (PMID:21307346) RGD PMID:19158077 PMID:21307346 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695
JBrowse link
G Sdcbp syndecan binding protein involved_in ISO
ISS
(PMID:25893292)
GO_REF:0000024
RGD
UniProt
PMID:25893292 GO_REF:0000024 NCBI chr 5:19,471,664...19,498,499
Ensembl chr 5:19,471,664...19,498,485
JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:20527027) RGD PMID:20527027 NCBI chr13:27,186,701...27,193,211
Ensembl chr13:27,187,130...27,192,592
JBrowse link
G Smad2 SMAD family member 2 involved_in ISO (MGI:2683382|PMID:14691138) RGD PMID:14691138 MGI:2683382 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (PMID:18505915), (PMID:21307346) RGD PMID:18505915 PMID:21307346 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:2683382|PMID:14691138)
Ensembl
RGD
PMID:14691138 GO_REF:0000107 MGI:2683382 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:20018240), (PMID:23288509)
(MGI:4837019|PMID:20890042), (MGI:5548026|PMID:24239292)
RGD PMID:20018240 PMID:20890042 PMID:23288509 PMID:24239292 MGI:4837019 MGI:5548026 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Tbx20 T-box transcription factor 20 involved_in IEA
ISO
GO_REF:0000107
(MGI:5299248|PMID:21983003)
Ensembl
RGD
PMID:21983003 GO_REF:0000107 MGI:5299248 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within
involved_in
ISS
ISO
GO_REF:0000024
(MGI:3821807|PMID:18794329)
(PMID:17999987), (PMID:18505915)
UniProt
RGD
PMID:17999987 PMID:18505915 PMID:18794329 GO_REF:0000024 MGI:3821807 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:199,664,039...199,670,970
Ensembl chr 1:199,664,173...199,670,961
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17999987), (PMID:18505915)
AgBase
RGD
UniProt
PMID:17999987 PMID:18505915 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:2683382|PMID:14691138)
(PMID:18505915), (PMID:18718461)
AgBase
RGD
PMID:14691138 PMID:18505915 PMID:18718461 GO_REF:0000024 MGI:2683382 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO UniProtKB:P10600 (MGI:3820811|PMID:18718461) RGD PMID:18718461 MGI:3820811 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (PMID:26459119) RGD PMID:26459119 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:18297062)
(MGI:4838344|PMID:20804746), (MGI:5284765|PMID:18297062), (MGI:5284780|PMID:17332324)
RGD PMID:17332324 PMID:18297062 PMID:20804746 MGI:4838344 MGI:5284765 MGI:5284780 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 involved_in ISO (PMID:18227151) RGD PMID:18227151 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (MGI:4940410|PMID:21317240) RGD PMID:21317240 MGI:4940410 NCBI chr16:69,237,857...69,242,028
Ensembl chr16:69,237,857...69,242,028
JBrowse link
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3610266|PMID:16140292)
Ensembl
RGD
PMID:16140292 GO_REF:0000107 MGI:3610266 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Eng endoglin involved_in ISO (MGI:4368063|PMID:19703439) RGD PMID:19703439 MGI:4368063 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (MGI:3820811|PMID:18718461) RGD PMID:18718461 MGI:3820811 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clasp1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr13:34,365,038...34,584,651
Ensembl chr13:34,365,147...34,584,651
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO
IEA
(PMID:23940118)
GO_REF:0000107
RGD
Ensembl
PMID:23940118 GO_REF:0000107 NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495
JBrowse link
G Dag1 dystroglycan 1 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5438719|PMID:22768269)
UniProt
RGD
PMID:22768269 GO_REF:0000024 MGI:5438719 NCBI chr 3:113,400,395...113,405,869
Ensembl chr 3:113,401,734...113,405,829
JBrowse link
G Epha3 Eph receptor A3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3703403|PMID:17046737)
UniProt
RGD
PMID:17046737 GO_REF:0000024 MGI:3703403 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:16816361) RGD PMID:16816361 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G LOC103690035 TGF-beta receptor type-1-like involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:64,565,358...64,585,219
Ensembl chr 5:64,566,804...64,584,309
JBrowse link
G Mcrip1 MAPK regulated co-repressor interacting protein 1 involved_in ISO
ISS
(PMID:25728771)
GO_REF:0000024
RGD
UniProt
PMID:25728771 GO_REF:0000024 NCBI chr10:109,720,144...109,727,595
Ensembl chr10:109,720,144...109,722,195
JBrowse link
G Phldb1 pleckstrin homology-like domain, family B, member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:23940118)
Ensembl
RGD
PMID:23940118 GO_REF:0000107 NCBI chr 8:48,997,189...49,045,176
Ensembl chr 8:48,997,184...49,045,154
JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr11:60,042,879...60,051,229
Ensembl chr11:57,265,732...57,481,589
JBrowse link
G Pofut2 protein O-fucosyltransferase 2 acts_upstream_of_or_within ISO MGI:3604508|MGI:4127173 (MGI:4838381|PMID:20637190) RGD PMID:20637190 MGI:4838381 NCBI chr20:12,117,811...12,128,747
Ensembl chr20:12,117,811...12,128,747
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:24887517)
GO_REF:0000107
RGD
Ensembl
PMID:24887517 GO_REF:0000107 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 involved_in ISO (PMID:20826792) RGD PMID:20826792 NCBI chr11:29,931,083...30,061,173
Ensembl chr11:29,933,163...30,051,103
JBrowse link
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 NOT
NOT|involved_in
ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb3 transforming growth factor, beta 3 NOT
NOT|involved_in
ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT
NOT|involved_in
ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    cellular process 18900
      cellular developmental process 4487
        cell differentiation 4391
          mesenchymal cell differentiation 238
            epithelial to mesenchymal transition 156
              cardiac epithelial to mesenchymal transition + 38
              clearance of cells from fusion plate by epithelial to mesenchymal transition 0
              epicardial cell to mesenchymal cell transition 0
              mesodermal to mesenchymal transition involved in gastrulation + 3
              negative regulation of epithelial to mesenchymal transition + 35
              neural crest formation + 11
              positive regulation of epithelial to mesenchymal transition + 50
              regulation of epithelial to mesenchymal transition + 98
Path 2
Term Annotations click to browse term
  biological_process 20082
    developmental process 6853
      anatomical structure development 6313
        multicellular organism development 5789
          system development 5317
            animal organ development 4068
              mesenchyme development 298
                mesenchymal cell differentiation 238
                  epithelial to mesenchymal transition 156
                    cardiac epithelial to mesenchymal transition + 38
                    clearance of cells from fusion plate by epithelial to mesenchymal transition 0
                    epicardial cell to mesenchymal cell transition 0
                    mesodermal to mesenchymal transition involved in gastrulation + 3
                    negative regulation of epithelial to mesenchymal transition + 35
                    neural crest formation + 11
                    positive regulation of epithelial to mesenchymal transition + 50
                    regulation of epithelial to mesenchymal transition + 98
paths to the root