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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial to mesenchymal transition
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Accession:GO:0001837 term browser browse the term
Definition:A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
Synonyms:exact_synonym: EMT;   epithelial-mesenchymal transition;   mesenchymal cell differentiation from epithelial cell



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epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akna AT-hook transcription factor involved_in ISO
IBA
(MGI:6294240|PMID:30787442)
PMID:21873635
RGD PMID:30787442 PMID:21873635 MGI:6294240, RGD:13792537 NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:15110716)
(PMID:18184661)
(MGI:3640731|PMID:16730346), (MGI:5299248|PMID:21983003)
UniProt
RGD
PMID:15110716 PMID:16730346 PMID:18184661 PMID:21983003 GO_REF:0000024 MGI:3640731 MGI:5299248 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Cul7 cullin 7 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:20139075)
UniProt
Ensembl
RGD
PMID:20139075 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:14,319,102...14,333,035
Ensembl chr 9:14,319,108...14,332,741
JBrowse link
G Ddx17 DEAD-box helicase 17 involved_in ISO (PMID:24910439) RGD PMID:24910439 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:24910439) RGD PMID:24910439 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO (PMID:28169360) RGD PMID:28169360 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837
JBrowse link
G Eng endoglin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 involved_in ISO MGI:3578147 (MGI:3714667|PMID:17507402), (MGI:3821807|PMID:18794329) RGD PMID:17507402 PMID:18794329 MGI:3714667 MGI:3821807 NCBI chr13:30,673,052...30,770,213
Ensembl chr13:30,669,764...30,768,360
JBrowse link
G Fam83d family with sequence similarity 83, member D involved_in ISO (PMID:24344117) RGD PMID:24344117 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 involved_in ISO
IEA
(PMID:26451614)
GO_REF:0000107
RGD
Ensembl
PMID:26451614 GO_REF:0000107 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IDA RGD PMID:7803853 RGD:632663 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Flna filamin A acts_upstream_of_or_within ISO MGI:1923816 (MGI:5085960|PMID:21709252) RGD PMID:21709252 MGI:5085960 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO
IEA
ISS
(PMID:15448698)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15448698 GO_REF:0000024 GO_REF:0000107 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA
ISO
GO_REF:0000107
(MGI:3772289|PMID:18037992)
Ensembl
RGD
PMID:18037992 GO_REF:0000107 MGI:3772289 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS
(PMID:18832382)
GO_REF:0000024
RGD
UniProt
PMID:18832382 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B involved_in ISS
ISO
GO_REF:0000024
(MGI:3698386|PMID:17273560)
HGNC-UCL
RGD
PMID:17273560 GO_REF:0000024 MGI:3698386 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:2683382|PMID:14691138)
Ensembl
RGD
PMID:14691138 GO_REF:0000107 MGI:2683382 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lims1 LIM zinc finger domain containing 1 NOT|involved_in ISO (PMID:20926685) RGD PMID:20926685 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500
JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in ISO
ISS
IEA
(PMID:16096638)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:16096638 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
JBrowse link
G Loxl3 lysyl oxidase-like 3 involved_in ISO (PMID:16096638) RGD PMID:16096638 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466
JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (MGI:4418636|PMID:11023873) RGD PMID:11023873 MGI:4418636 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (MGI:3053252|PMID:15339668) RGD PMID:15339668 MGI:3053252 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nog noggin involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3783944|PMID:17218603)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17218603 GO_REF:0000024 GO_REF:0000107 MGI:3783944 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Notch1 notch receptor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:17984306)
MGI:1857230 (MGI:3027664|PMID:14701881)
RGD PMID:14701881 PMID:17984306 MGI:3027664 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notch4 notch receptor 4 involved_in ISO (PMID:17984306) RGD PMID:17984306 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha acts_upstream_of_or_within ISO MGI:3044031 (MGI:3053252|PMID:15339668) RGD PMID:15339668 MGI:3053252 NCBI chr14:91,556,743...91,606,230
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:1857411 (MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:3027664 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Rflnb refilin B acts_upstream_of_or_within ISO MGI:95556 (MGI:5085960|PMID:21709252) RGD PMID:21709252 MGI:5085960 NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P70336 (MGI:3513217|PMID:15464581)
Ensembl
RGD
PMID:15464581 GO_REF:0000107 MGI:3513217 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO UniProtKB:P70335 (MGI:3513217|PMID:15464581) RGD PMID:15464581 MGI:3513217 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in TAS
ISO
(MGI:1352954|PMID:10655586), (MGI:2153695|PMID:11689706), (MGI:5294539|PMID:18832382)
(PMID:16096638)
RGD PMID:10655586 PMID:11689706 PMID:16096638 PMID:18832382 PMID:15155580 MGI:1352954 MGI:2153695 MGI:5294539, RGD:1302246 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in
acts_upstream_of_or_within
ISO (PMID:17984306), (PMID:9182671)
MGI:2447175 (MGI:3762325|PMID:17916597)
(MGI:892810|PMID:9182671)
RGD PMID:9182671 PMID:17916597 PMID:17984306 MGI:3762325 MGI:892810 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2429649 (MGI:3041362|PMID:15096597)
UniProt
RGD
PMID:15096597 GO_REF:0000024 MGI:3041362 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within
involved_in
IDA
ISO
(PMID:29529050)
(PMID:25893292)
RGD PMID:25893292 PMID:29529050 PMID:10504497 RGD:1578678 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:10092230), (PMID:18223299)
AgBase
RGD
PMID:10092230 PMID:18223299 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:15761148) RGD PMID:15761148 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO
IBA
(PMID:18184661)
PMID:21873635
RGD PMID:18184661 PMID:21873635 RGD:13792537 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr12:2,600,934...2,604,222 JBrowse link
G Trim28 tripartite motif-containing 28 involved_in ISS
ISO
GO_REF:0000024
(MGI:3698386|PMID:17273560)
HGNC-UCL
RGD
PMID:17273560 GO_REF:0000024 MGI:3698386 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23819628 RGD:11535143 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799
JBrowse link
G Wnt11 Wnt family member 11 acts_upstream_of_or_within ISO MGI:98958 (MGI:5634837|PMID:25813538) RGD PMID:25813538 MGI:5634837 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294
JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA
(PMID:12841867)
GO_REF:0000107
RGD
Ensembl
PMID:12841867 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:12841867) RGD PMID:12841867 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS
(PMID:17072303)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17072303 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:17072303) RGD PMID:17072303 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 acts_upstream_of_or_within ISO (MGI:4458867|PMID:19156209) RGD PMID:19156209 MGI:4458867 NCBI chr 2:174,754,631...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA
(PMID:18184661)
GO_REF:0000107
RGD
Ensembl
PMID:18184661 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Olfm1 olfactomedin 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Rtn4 reticulon 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4458867|PMID:19156209)
Ensembl
RGD
PMID:19156209 GO_REF:0000107 MGI:4458867 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Tbx3 T-box transcription factor 3 involved_in ISO (PMID:22130515) RGD PMID:22130515 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:10092230)
AgBase
RGD
PMID:10092230 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (PMID:18184661) RGD PMID:18184661 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Wnt16 Wnt family member 16 acts_upstream_of_or_within ISO (MGI:4458867|PMID:19156209) RGD PMID:19156209 MGI:4458867 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380
JBrowse link
G Wnt2 Wnt family member 2 acts_upstream_of_or_within ISO MGI:4361155 (MGI:4439199|PMID:20159597) RGD PMID:20159597 MGI:4439199 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
endocardial cushion to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 NOT|involved_in ISO (MGI:2674189|PMID:12941632) RGD PMID:12941632 MGI:2674189 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Eng endoglin NOT|involved_in ISO (MGI:2674189|PMID:12941632) RGD PMID:12941632 MGI:2674189 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Has2 hyaluronan synthase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:1861536|PMID:10930438)
UniProt
RGD
PMID:10930438 GO_REF:0000024 MGI:1861536 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
JBrowse link
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Erg ETS transcription factor ERG acts_upstream_of_or_within ISO MGI:5443838 (MGI:5442628|PMID:22932696) RGD PMID:22932696 MGI:5442628 NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1341884 (MGI:3530185|PMID:15680351) RGD PMID:15680351 MGI:3530185 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:1341800 (MGI:3530185|PMID:15680351) RGD PMID:15680351 MGI:3530185 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd4 programmed cell death 4 involved_in IGI PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in IGI PMID:23441172 BHF-UCL PMID:23441172 RGD:10400865 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 NOT|involved_in ISO (MGI:3814273|PMID:18924235) RGD PMID:18924235 MGI:3814273 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Eng endoglin involved_in ISO (MGI:4368063|PMID:19703439) RGD PMID:19703439 MGI:4368063 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Fgf8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within
ISO (MGI:4359139|PMID:19509466)
(MGI:5002778|PMID:21364285)
RGD PMID:19509466 PMID:21364285 MGI:4359139 MGI:5002778 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1860511 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like acts_upstream_of_or_within ISO MGI:1341800 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152
JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:97169 (MGI:3810851|PMID:18667074) RGD PMID:18667074 MGI:3810851 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97168 (MGI:3810851|PMID:18667074)
Ensembl
RGD
PMID:18667074 GO_REF:0000107 MGI:3810851 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:3027664 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:3027664 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:4946551|PMID:21330551)
Ensembl
RGD
PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO UniProtKB:Q3UZ96 (MGI:3808643|PMID:18663143) RGD PMID:18663143 MGI:3808643 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO MGI:2447175 (MGI:3808643|PMID:18663143) RGD PMID:18663143 MGI:3808643 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within ISO MGI:5432904 (MGI:5613881|PMID:25318679) RGD PMID:25318679 MGI:5613881 NCBI chr10:74,854,779...74,861,147
Ensembl chr10:74,854,468...74,862,941
JBrowse link
mesodermal to mesenchymal transition involved in gastrulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in ISO (MGI:3772748|PMID:18171685) RGD PMID:18171685 MGI:3772748 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
JBrowse link
G Tasor transcription activation suppressor involved_in ISO (MGI:6109647|PMID:28839193) RGD PMID:28839193 MGI:6109647 NCBI chr16:2,606,807...2,669,902
Ensembl chr16:2,603,936...2,667,292
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:101948 (MGI:5634837|PMID:25813538)
Ensembl
RGD
PMID:25813538 GO_REF:0000107 MGI:5634837 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
negative regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 involved_in ISO (PMID:23776679) RGD PMID:23776679 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA
ISS
(PMID:20080667), (PMID:20154697)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20080667 PMID:20154697 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 acts_upstream_of_or_within ISO MGI:5515616 (MGI:5503293|PMID:23580654) RGD PMID:23580654 MGI:5503293 NCBI chr 1:77,546,900...77,558,631
Ensembl chr 1:77,546,900...77,558,630
JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Epha4 Eph receptor A4 involved_in ISO
IEA
(PMID:29093007)
GO_REF:0000107
RGD
Ensembl
PMID:29093007 GO_REF:0000107 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Foxa1 forkhead box A1 involved_in IEA
ISO
GO_REF:0000107
(PMID:20160041)
Ensembl
RGD
PMID:20160041 GO_REF:0000107 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa2 forkhead box A2 involved_in IEA
ISO
GO_REF:0000107
(PMID:20160041)
Ensembl
RGD
PMID:20160041 GO_REF:0000107 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of ISO (PMID:26451614) RGD PMID:26451614 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Hpn hepsin involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:19843851)
UniProt
Ensembl
RGD
PMID:19843851 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Il17rd interleukin 17 receptor D involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr16:2,228,467...2,295,126
Ensembl chr16:2,228,287...2,292,556
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in ISO (PMID:24627487) RGD PMID:24627487 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:19443654) RGD PMID:19443654 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Mark1 microtubule affinity regulating kinase 1 involved_in ISO
IEA
(PMID:31281935)
GO_REF:0000107
RGD
Ensembl
PMID:31281935 GO_REF:0000107 NCBI chr13:96,450,189...96,555,304
Ensembl chr13:96,451,487...96,555,173
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19293183)
Ensembl
RGD
PMID:19293183 GO_REF:0000107 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
JBrowse link
G Ovol2 ovo-like zinc finger 2 involved_in ISO (MGI:5574425|PMID:24735879), (MGI:6284898|PMID:28455959) RGD PMID:24735879 PMID:28455959 MGI:5574425 MGI:6284898 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:20080667) RGD PMID:20080667 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:27919618) RGD PMID:27919618 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 acts_upstream_of_or_within ISO (MGI:5529200|PMID:23983127)
(PMID:23983127)
RGD PMID:23983127 MGI:5529200 NCBI chr 1:207,139,070...207,167,830
Ensembl chr 1:207,139,112...207,168,616
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:19095296)
GO_REF:0000107
RGD
Ensembl
PMID:19095296 GO_REF:0000107 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:19095296) RGD PMID:19095296 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414689|PMID:25576668)
UniProt
RGD
PMID:25576668 GO_REF:0000024 MGI:6414689 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162
JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (MGI:3762085|PMID:17823118) RGD PMID:17823118 MGI:3762085 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Trim62 tripartite motif-containing 62 acts_upstream_of_or_within ISO MGI:5538538 (MGI:5585203|PMID:24890125) RGD PMID:24890125 MGI:5585203 NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:20813961 RGD:11568680 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Usf3 upstream transcription factor family member 3 involved_in ISO (PMID:28011713) RGD PMID:28011713 NCBI chr11:56,470,738...56,529,736
Ensembl chr11:56,476,122...56,529,884
JBrowse link
G Vasn vasorin involved_in ISO (PMID:21170088) RGD PMID:21170088 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Znf750 zinc finger protein 750 involved_in ISO (PMID:32042337) RGD PMID:32042337 NCBI chr10:106,772,162...106,781,186
Ensembl chr10:106,772,669...106,781,200
JBrowse link
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nog noggin involved_in IEA
ISO
GO_REF:0000107
(MGI:3783944|PMID:17218603)
Ensembl
RGD
PMID:17218603 GO_REF:0000107 MGI:3783944 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
negative regulation of neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fuz fuzzy planar cell polarity protein involved_in ISS
ISO
GO_REF:0000024
(MGI:5498583|PMID:23806618)
UniProt
RGD
PMID:23806618 GO_REF:0000024 MGI:5498583 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
neural crest cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 involved_in ISO MGI:1857637 (MGI:5532613|PMID:23933587) RGD PMID:23933587 MGI:5532613 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A involved_in ISO
IEA
MGI:1857473|MGI:3773698|MGI:4867385 (MGI:3700083|PMID:17294360), (MGI:5532613|PMID:23933587)
GO_REF:0000107
RGD
Ensembl
PMID:17294360 PMID:23933587 GO_REF:0000107 MGI:3700083 MGI:5532613 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3045799 (MGI:4437369|PMID:20130188)
Ensembl
RGD
PMID:20130188 GO_REF:0000107 MGI:4437369 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsc goosecoid homeobox involved_in ISO (PMID:24290375) RGD PMID:24290375 NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111
JBrowse link
neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrd chordin involved_in ISO MGI:2157350 (MGI:3721005|PMID:17685487) RGD PMID:17685487 MGI:3721005 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673
JBrowse link
G Kbtbd8 kelch repeat and BTB domain containing 8 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26399832)
UniProt
Ensembl
RGD
PMID:26399832 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:127,675,967...127,688,785
Ensembl chr 4:127,676,141...127,687,697
JBrowse link
G Klhl12 kelch-like family member 12 involved_in ISO
ISS
IEA
(PMID:27716508)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:27716508 GO_REF:0000024 GO_REF:0000107 NCBI chr13:45,899,913...45,933,648
Ensembl chr13:45,899,928...45,933,643
JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in ISO
IBA
(PMID:11029007)
PMID:21873635
RGD PMID:11029007 PMID:21873635 RGD:13792537 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 involved_in ISO
ISS
(PMID:26399832)
GO_REF:0000024
RGD
UniProt
PMID:26399832 GO_REF:0000024 NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
JBrowse link
G Pdcd6 programmed cell death 6 involved_in ISS
ISO
GO_REF:0000024
(PMID:27716508)
UniProt
RGD
PMID:27716508 GO_REF:0000024 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189
JBrowse link
G Pef1 penta-EF hand domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:27716508)
UniProt
RGD
PMID:27716508 GO_REF:0000024 NCBI chr 5:142,451,791...142,475,061
Ensembl chr 5:142,451,778...142,475,067
JBrowse link
G Polr1b RNA polymerase I subunit B involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379
JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 involved_in ISO (PMID:26399832) RGD PMID:26399832 NCBI chr18:54,267,015...54,300,324
Ensembl chr18:54,267,026...54,300,324
JBrowse link
positive regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag1 jagged canonical Notch ligand 1 involved_in IGI PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Notch1 notch receptor 1 involved_in IGI PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:5300829|PMID:22186728) RGD PMID:22186728 MGI:5300829 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:21743278 RGD:7243870 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Alx1 ALX homeobox 1 involved_in ISO
ISS
(PMID:23288509)
GO_REF:0000024
RGD
UniProt
PMID:23288509 GO_REF:0000024 NCBI chr 7:38,157,626...38,177,220
Ensembl chr 7:38,147,117...38,177,220
JBrowse link
G Axin2 axin 2 involved_in ISO
IEA
(PMID:17072303)
GO_REF:0000107
RGD
Ensembl
PMID:17072303 GO_REF:0000107 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO (PMID:19328798) RGD PMID:19328798 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bcl9l BCL9 like involved_in ISO (PMID:19328798) RGD PMID:19328798 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3583785 (MGI:3611958|PMID:16314491)
(PMID:20890042)
Ensembl
RGD
PMID:16314491 PMID:20890042 GO_REF:0000107 MGI:3611958 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P23359 (MGI:5502250|PMID:23863481)
Ensembl
RGD
PMID:23863481 GO_REF:0000107 MGI:5502250 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO UniProtKB:P21275 (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Col1a1 collagen type I alpha 1 chain involved_in ISO (PMID:20018240) RGD PMID:20018240 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Crb2 crumbs cell polarity complex component 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5296388|PMID:22072575), (MGI:5823085|PMID:27870829)
CAFA
RGD
PMID:22072575 PMID:27870829 GO_REF:0000024 MGI:5296388 MGI:5823085 NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO UniProtKB:Q9NX18 (PMID:23983127) RGD PMID:23983127 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:5442513|PMID:15734730)
Ensembl
RGD
PMID:15734730 GO_REF:0000107 MGI:5442513 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:20154697) RGD PMID:20154697 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:24226523) RGD PMID:24226523 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (PMID:22991501) RGD PMID:22991501 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) involved_in ISO (PMID:21750175)
(MGI:5545971|PMID:21750175)
RGD PMID:21750175 MGI:5545971 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
JBrowse link
G Glipr2 GLI pathogenesis-related 2 involved_in ISO (PMID:23516513) RGD PMID:23516513 NCBI chr 5:58,170,417...58,200,947
Ensembl chr 5:58,170,425...58,202,272
JBrowse link
G Hdac2 histone deacetylase 2 IMP RGD PMID:19553350 RGD:9590229 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Il1b interleukin 1 beta involved_in IEA
ISO
GO_REF:0000107
(PMID:25204733)
Ensembl
RGD
PMID:25204733 GO_REF:0000107 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:25916550) RGD PMID:25916550 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IMP PMID:23270756 BHF-UCL PMID:23270756 RGD:13210526 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in ISO
IEA
(PMID:20018240)
GO_REF:0000107
RGD
Ensembl
PMID:20018240 GO_REF:0000107 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24239292)
UniProt
Ensembl
RGD
PMID:24239292 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
JBrowse link
G Mdk midkine involved_in ISO
ISS
(PMID:18469519)
GO_REF:0000024
RGD
UniProt
PMID:18469519 GO_REF:0000024 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:27919618) RGD PMID:27919618 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myocd myocardin involved_in IMP PMID:23270756 BHF-UCL PMID:23270756 RGD:13210526 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:4837019 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Olfm1 olfactomedin 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Pdpn podoplanin involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17046996), (PMID:21376833)
UniProt
RGD
PMID:17046996 PMID:21376833 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19158077), (PMID:21307346) RGD PMID:19158077 PMID:21307346 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Sdcbp syndecan binding protein involved_in ISO
ISS
(PMID:25893292)
GO_REF:0000024
RGD
UniProt
PMID:25893292 GO_REF:0000024 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:20527027) RGD PMID:20527027 NCBI chr13:23,274,120...23,280,082
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Smad2 SMAD family member 2 involved_in ISO (MGI:2683382|PMID:14691138) RGD PMID:14691138 MGI:2683382 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (PMID:18505915), (PMID:21307346) RGD PMID:18505915 PMID:21307346 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:2683382|PMID:14691138)
Ensembl
RGD
PMID:14691138 GO_REF:0000107 MGI:2683382 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:20018240), (PMID:23288509)
(MGI:4837019|PMID:20890042), (MGI:5548026|PMID:24239292)
RGD PMID:20018240 PMID:20890042 PMID:23288509 PMID:24239292 MGI:4837019 MGI:5548026 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:5299248|PMID:21983003) RGD PMID:21983003 MGI:5299248 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:17999987), (PMID:18505915)
(MGI:3821807|PMID:18794329)
GO_REF:0000024
RGD
UniProt
PMID:17999987 PMID:18505915 PMID:18794329 GO_REF:0000024 MGI:3821807 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17999987), (PMID:18505915)
AgBase
RGD
PMID:17999987 PMID:18505915 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:2683382|PMID:14691138)
(PMID:18505915), (PMID:18718461)
AgBase
RGD
PMID:14691138 PMID:18505915 PMID:18718461 GO_REF:0000024 MGI:2683382 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO UniProtKB:P10600 (MGI:3820811|PMID:18718461) RGD PMID:18718461 MGI:3820811 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (PMID:26459119) RGD PMID:26459119 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:18297062)
(MGI:4838344|PMID:20804746), (MGI:5284765|PMID:18297062), (MGI:5284780|PMID:17332324)
RGD PMID:17332324 PMID:18297062 PMID:20804746 MGI:4838344 MGI:5284765 MGI:5284780 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 involved_in ISO (PMID:18227151) RGD PMID:18227151 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (MGI:4940410|PMID:21317240) RGD PMID:21317240 MGI:4940410 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677
JBrowse link
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3610266|PMID:16140292)
Ensembl
RGD
PMID:16140292 GO_REF:0000107 MGI:3610266 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Eng endoglin involved_in ISO (MGI:4368063|PMID:19703439) RGD PMID:19703439 MGI:4368063 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA
(MGI:3820811|PMID:18718461)
GO_REF:0000107
RGD
Ensembl
PMID:18718461 GO_REF:0000107 MGI:3820811 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clasp1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731
JBrowse link
G Dag1 dystroglycan 1 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5438719|PMID:22768269)
UniProt
RGD
PMID:22768269 GO_REF:0000024 MGI:5438719 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132
JBrowse link
G Epha3 Eph receptor A3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3703403|PMID:17046737)
UniProt
RGD
PMID:17046737 GO_REF:0000024 MGI:3703403 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:16816361) RGD PMID:16816361 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Mcrip1 MAPK regulated co-repressor interacting protein 1 involved_in ISO
ISS
(PMID:25728771)
GO_REF:0000024
RGD
UniProt
PMID:25728771 GO_REF:0000024 NCBI chr10:105,820,656...105,828,146
Ensembl chr10:105,820,656...105,828,271
JBrowse link
G Phldb1 pleckstrin homology-like domain, family B, member 1 involved_in ISO
IEA
(PMID:23940118)
GO_REF:0000107
RGD
Ensembl
PMID:23940118 GO_REF:0000107 NCBI chr 8:45,003,538...45,051,541
Ensembl chr 8:45,003,538...45,051,522
JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 involved_in ISO (PMID:23940118) RGD PMID:23940118 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467
JBrowse link
G Pofut2 protein O-fucosyltransferase 2 acts_upstream_of_or_within ISO MGI:3604508|MGI:4127173 (MGI:4838381|PMID:20637190) RGD PMID:20637190 MGI:4838381 NCBI chr20:11,367,073...11,377,788
Ensembl chr20:11,367,096...11,377,743
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:24887517)
GO_REF:0000107
RGD
Ensembl
PMID:24887517 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 involved_in ISO (PMID:20826792) RGD PMID:20826792 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901
JBrowse link
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 NOT|involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb3 transforming growth factor, beta 3 NOT|involved_in ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19812
    cellular process 18617
      cellular developmental process 4595
        cell differentiation 4499
          mesenchymal cell differentiation 242
            epithelial to mesenchymal transition 158
              cardiac epithelial to mesenchymal transition + 37
              clearance of cells from fusion plate by epithelial to mesenchymal transition 0
              epicardial cell to mesenchymal cell transition 0
              mesodermal to mesenchymal transition involved in gastrulation + 3
              negative regulation of epithelial to mesenchymal transition + 35
              neural crest formation + 15
              positive regulation of epithelial to mesenchymal transition + 50
              regulation of epithelial to mesenchymal transition + 97
Path 2
Term Annotations click to browse term
  biological_process 19812
    developmental process 6948
      anatomical structure development 6361
        multicellular organism development 5787
          system development 5427
            animal organ development 4181
              mesenchyme development 301
                mesenchymal cell differentiation 242
                  epithelial to mesenchymal transition 158
                    cardiac epithelial to mesenchymal transition + 37
                    clearance of cells from fusion plate by epithelial to mesenchymal transition 0
                    epicardial cell to mesenchymal cell transition 0
                    mesodermal to mesenchymal transition involved in gastrulation + 3
                    negative regulation of epithelial to mesenchymal transition + 35
                    neural crest formation + 15
                    positive regulation of epithelial to mesenchymal transition + 50
                    regulation of epithelial to mesenchymal transition + 97
paths to the root