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ONTOLOGY REPORT - ANNOTATIONS

Term:release of cytochrome c from mitochondria
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Accession:GO:0001836 term browser browse the term
Definition:The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.
Comment:The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that are directly involved in this process. An example is Drp1 (DNM1L, UniProt symbol O00429) in PMID:20850011.


show annotations for term's descendants           Sort by:
 
release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (MGI:3760368|PMID:11311799) RGD PMID:11311799 MGI:3760368 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3029528 (MGI:3029504|PMID:12431371)		 RGD PMID:12431371 PMID:21873635 MGI:3029504, RGD:13792537 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in IMP
ISO		 positive regulation
(MGI:5009197|PMID:10950869)
UniProtKB:O08734 (PMID:16199525), (PMID:21041309), (PMID:9843949)		 RGD PMID:9843949 PMID:10950869 PMID:16199525 PMID:21041309 PMID:18252800 MGI:5009197, RGD:2313987 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA		 MGI:108093|MGI:98834 (MGI:1203837|PMID:9560217), (MGI:2677915|PMID:12925707), (MGI:2681362|PMID:14623868), (MGI:3028818|PMID:14614769), (MGI:3042308|PMID:14963330), (MGI:3688960|PMID:17052454)
(PMID:16199525), (PMID:17052454), (PMID:25609812), (PMID:9843949)
PMID:21873635		 RGD PMID:9560217 PMID:9843949 PMID:12925707 PMID:14614769 PMID:14623868 More... MGI:1203837 MGI:2677915 MGI:2681362 MGI:3028818 MGI:3042308 MGI:3688960, RGD:14394498, RGD:13792537 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IBA
ISO		 PMID:21873635
(PMID:11463392)		 RGD PMID:11463392 PMID:21873635 RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISS
ISO		 PMID:9843949
(MGI:3700463|PMID:9843949)		 RGD PMID:9843949 PMID:9843949 MGI:3700463, RGD:8554139 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:9843949)
MGI:99702 (MGI:3688960|PMID:17052454)		 RGD PMID:9843949 PMID:17052454 MGI:3688960 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within
involved_in		 IDA
ISO		 (MGI:4940333|PMID:9873064)
MGI:2158671 (MGI:2137769|PMID:11369777)
(MGI:5619478|PMID:18084238)
(PMID:17052454)		 RGD PMID:9873064 PMID:11369777 PMID:17052454 PMID:18084238 PMID:18252800 MGI:2137769 MGI:4940333 MGI:5619478, RGD:2313987 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (PMID:27505430) RGD PMID:27505430 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp2 caspase 2 involved_in ISO (PMID:12065594) RGD PMID:12065594 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (PMID:20850011) RGD PMID:20850011 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:19864424) RGD PMID:19864424 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase involved_in ISO (PMID:16765912) RGD PMID:16765912 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IMP induces release following removal of NGF from sympathetic neurons RGD PMID:11301023 RGD:2290592 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:15504737 RGD:2298783 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mff mitochondrial fission factor involved_in ISO
IEA		 (PMID:18353969)
GO_REF:0000107		 RGD
Ensembl		 PMID:18353969 GO_REF:0000107 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within
involved_in		 ISO MGI:2678372 (MGI:2675761|PMID:12952892)
(MGI:5009174|PMID:14699081)		 RGD PMID:12952892 PMID:14699081 MGI:2675761 MGI:5009174 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Sfn stratifin involved_in ISO (PMID:11574543) RGD PMID:11574543 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857344|MGI:1857480 (MGI:3654558|PMID:10212301), (MGI:3691744|PMID:15642323) RGD PMID:10212301 PMID:15642323 MGI:3654558 MGI:3691744 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Timm50 translocase of inner mitochondrial membrane 50 acts_upstream_of_or_within ISO (PMID:15044455) RGD PMID:15044455 NCBI chr 1:83,574,872...83,582,769
Ensembl chr 1:83,556,757...83,582,793 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:99702 (MGI:3042308|PMID:14963330), (MGI:3574697|PMID:15483136) RGD PMID:14963330 PMID:15483136 MGI:3042308 MGI:3574697 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO (MGI:3574697|PMID:15483136) RGD PMID:15483136 MGI:3574697 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
negative regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5294538|PMID:18977203)		 UniProt
RGD		 PMID:18977203 GO_REF:0000024 MGI:5294538 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Avp arginine vasopressin involved_in ISO (PMID:18402937) RGD PMID:18402937 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:9393856)
(PMID:15901672), (PMID:9393856)		 RGD PMID:9393856 PMID:15901672 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l2 Bcl2-like 2 IDA RGD PMID:10724126 RGD:14394498 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Fxn frataxin involved_in IEA
ISO		 GO_REF:0000107
(PMID:16608849)		 Ensembl
RGD		 PMID:16608849 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,841
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein involved_in ISO (PMID:18417609) RGD PMID:18417609 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA		 (PMID:12221075)
GO_REF:0000107		 RGD
Ensembl		 PMID:12221075 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hgf hepatocyte growth factor involved_in ISO (PMID:20655899) RGD PMID:20655899 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within ISO (MGI:5306879|PMID:21856340) RGD PMID:21856340 MGI:5306879 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5294538|PMID:18977203)		 UniProt
RGD		 PMID:18977203 GO_REF:0000024 MGI:5294538 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4879057|PMID:21151901)		 Ensembl
RGD		 PMID:21151901 GO_REF:0000107 MGI:4879057 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:18006463 RGD:12738362 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
ISO
IBA
IEA		 PMID:10590251
(PMID:15004034)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:15004034 PMID:10590251 PMID:21873635 GO_REF:0000107, RGD:10047155, RGD:13792537 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO		 GO_REF:0000024
(PMID:21149567)
(MGI:3692706|PMID:16839884)		 ParkinsonsUK-UCL
RGD		 PMID:16839884 PMID:21149567 GO_REF:0000024 MGI:3692706 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO		 GO_REF:0000024
(MGI:3692706|PMID:16839884)		 ParkinsonsUK-UCL
RGD		 PMID:16839884 GO_REF:0000024 MGI:3692706 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO		 GO_REF:0000024
(PMID:19228691)		 UniProt
RGD		 PMID:19228691 GO_REF:0000024 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Prelid1 PRELI domain containing 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr17:9,305,349...9,308,389
Ensembl chr17:9,305,361...9,308,407 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS		 (PMID:19880420), (PMID:23453807)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:19880420 PMID:23453807 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
ISS		 (PMID:19729910)
GO_REF:0000024		 RGD
UniProt		 PMID:19729910 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,126
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
positive regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:17289999) RGD PMID:17289999 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 IMP RGD PMID:12485416 RGD:2317097 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
ISS		 (PMID:14963330), (PMID:21262771)
GO_REF:0000024		 RGD
UniProt		 PMID:14963330 PMID:21262771 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO
IEA
IBA		 UniProtKB:P70444 (PMID:21041309)
GO_REF:0000002
PMID:21873635		 RGD
InterPro		 PMID:21041309 PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2l11 Bcl2-like 11 involved_in ISO UniProtKB:P70444 (PMID:17289999), (PMID:21041309) RGD PMID:17289999 PMID:21041309 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
UniProtKB:P70444 (PMID:17289999), (PMID:21041309), (PMID:21262771), (PMID:32029622)
UniProtKB:O08734|UniProtKB:P70444 (MGI:5009197|PMID:10950869), (MGI:5009775|PMID:21041309)		 UniProt
RGD		 PMID:10950869 PMID:17289999 PMID:21041309 PMID:21262771 PMID:32029622 More... GO_REF:0000024 MGI:5009197 MGI:5009775, RGD:13792537 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bik BCL2-interacting killer involved_in ISO (PMID:21041309) RGD PMID:21041309 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Bmf Bcl2 modifying factor involved_in ISO UniProtKB:P70444 (MGI:5009775|PMID:21041309) RGD PMID:21041309 MGI:5009775 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Casp1 caspase 1 involved_in ISO (MGI:3029677|PMID:14663141) RGD PMID:14663141 MGI:3029677 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cideb cell death-inducing DFFA-like effector b involved_in ISO (PMID:12595532) RGD PMID:12595532 NCBI chr15:29,252,203...29,256,759
Ensembl chr15:29,252,213...29,256,605 		JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (PMID:21149567) RGD PMID:21149567 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Fam162a family with sequence similarity 162, member A involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5319617|PMID:15082785)
(PMID:15082785)
PMID:21873635		 UniProt
RGD		 PMID:15082785 PMID:21873635 GO_REF:0000024 MGI:5319617, RGD:13792537 NCBI chr11:64,680,937...64,711,239
Ensembl chr11:64,680,323...64,711,239 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Hrk harakiri, BCL2 interacting protein involved_in ISO (PMID:21041309) RGD PMID:21041309 NCBI chr12:38,387,484...38,409,652 JBrowse link
G LOC120095320 protein FAM162A-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:36,389,447...36,391,357
Ensembl chr10:36,390,113...36,390,613 		JBrowse link
G Mff mitochondrial fission factor involved_in ISO
IEA		 (PMID:21149567)
GO_REF:0000107		 RGD
Ensembl		 PMID:21149567 GO_REF:0000107 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:18852119)
PMID:21873635		 UniProt
RGD		 PMID:18852119 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in ISO
IEA		 (PMID:22984561)
GO_REF:0000107		 RGD
Ensembl		 PMID:22984561 GO_REF:0000107 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643 		JBrowse link
G Pdcd5 programmed cell death 5 involved_in ISO (PMID:16374546) RGD PMID:16374546 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19880420) RGD PMID:19880420 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Pla2g6 phospholipase A2 group VI IDA RGD PMID:18936091 RGD:6482750 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) RGD PMID:22984561 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14500711), (PMID:14699081), (PMID:15705586), (PMID:17289999) RGD PMID:14500711 PMID:14699081 PMID:15705586 PMID:17289999 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO		 GO_REF:0000024
(MGI:3575990|PMID:15800627)		 UniProt
RGD		 PMID:15800627 GO_REF:0000024 MGI:3575990 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in ISO (PMID:22266862) RGD PMID:22266862 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:14963330) RGD PMID:14963330 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Wdr35 WD repeat domain 35 IMP RGD PMID:23289926 RGD:11553920 NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029 		JBrowse link
regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plscr3 phospholipid scramblase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:14573790), (PMID:18358005)		 UniProt
RGD		 PMID:14573790 PMID:18358005 GO_REF:0000024 NCBI chr10:54,566,556...54,573,240
Ensembl chr10:54,566,873...54,578,709 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    signaling 7674
      signal transduction 7105
        apoptotic signaling pathway 638
          release of cytochrome c from mitochondria 65
            negative regulation of release of cytochrome c from mitochondria 23
            positive regulation of release of cytochrome c from mitochondria 30
            regulation of release of cytochrome c from mitochondria + 52
Path 2
Term Annotations click to browse term
  biological_process 20094
    cellular process 18691
      cellular component organization or biogenesis 6758
        cellular component organization 6506
          organelle organization 3660
            mitochondrion organization 600
              apoptotic mitochondrial changes 124
                release of cytochrome c from mitochondria 65
                  negative regulation of release of cytochrome c from mitochondria 23
                  positive regulation of release of cytochrome c from mitochondria 30
                  regulation of release of cytochrome c from mitochondria + 52
paths to the root