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ONTOLOGY REPORT - ANNOTATIONS


Term:serotonin secretion
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Accession:GO:0001820 term browser browse the term
Definition:The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.
Synonyms:exact_synonym: 5-HT secretion;   5-hydroxytryptamine secretion
 related_synonym: serotonin release



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serotonin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO MGI:2383982 (MGI:85068|PMID:9000133), (MGI:86632|PMID:8252632) RGD PMID:8252632 PMID:9000133 MGI:85068 MGI:86632 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fcgr2a Fc gamma receptor IIa acts_upstream_of_or_within ISO (MGI:78617|PMID:8552190) RGD PMID:8552190 MGI:78617 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO MGI:2384078 (MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:85068 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
negative regulation of serotonin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule acts_upstream_of_or_within ISO (MGI:3721168|PMID:12874256) RGD PMID:12874256 MGI:3721168 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Cnr1 cannabinoid receptor 1 involved_in IMP PMID:30217553 CACAO PMID:30217553 RGD:15023474 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Hrh3 histamine receptor H3 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:15470136 PMID:21873635 RGD:1626430, RGD:13792537 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISS
ISO
GO_REF:0000024
(MGI:1098377|PMID:9349547)
UniProt
RGD
PMID:9349547 GO_REF:0000024 MGI:1098377 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:15260125 RGD:6480684 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
positive regulation of serotonin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:20655906 RGD:5130946 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Lgals3 galectin 3 IDA RGD PMID:8347574 RGD:9685207 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Slc6a4 solute carrier family 6 member 4 IMP RGD PMID:25261262 RGD:11532763 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
regulation of serotonin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA RGD PMID:21947356 RGD:5507821 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in ISS
ISO
GO_REF:0000024
(MGI:1314969|PMID:9826725)
UniProt
RGD
PMID:9826725 GO_REF:0000024 MGI:1314969 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule acts_upstream_of_or_within ISO (MGI:3721168|PMID:12874256) RGD PMID:12874256 MGI:3721168 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig involved_in ISO (MGI:87668|PMID:9171347) RGD PMID:9171347 MGI:87668 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO MGI:2181608 (MGI:2671726|PMID:12913094) RGD PMID:12913094 MGI:2671726 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:87668|PMID:9171347)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9171347 GO_REF:0000024 GO_REF:0000107 MGI:87668 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
serotonin secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xbp1 X-box binding protein 1 IDA RGD PMID:16889758 RGD:2326003 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    signaling 7512
      cell-cell signaling 1749
        signal release 625
          serotonin secretion 17
            negative regulation of serotonin secretion 6
            positive regulation of serotonin secretion 3
            regulation of serotonin secretion + 11
            serotonin secretion involved in inflammatory response + 4
            serotonin secretion, neurotransmission 1
Path 2
Term Annotations click to browse term
  biological_process 19541
    localization 6501
      establishment of localization 4895
        transport 4733
          secretion 1170
            secretion by cell 967
              signal release 625
                serotonin secretion 17
                  negative regulation of serotonin secretion 6
                  positive regulation of serotonin secretion 3
                  regulation of serotonin secretion + 11
                  serotonin secretion involved in inflammatory response + 4
                  serotonin secretion, neurotransmission 1
paths to the root